The Binding of Isaac: Repentance

Repentance is out! - Spoiler warning! Every single Repentance item and trinket effect is listed below.

Repentance Items (168)

  • Clear Rune

    ItemID: 263

    "Rune mimic"

    Quality: 2

    When used, copies the effect of the Rune or Soul stone you are holding (like the Blank Card)

    Drops a random rune on the floor when picked up

    The recharge time of this item depends on the Rune/Soul Stone held:

    1 room: Soul of Lazarus

    2 rooms: Rune of Ansuz, Rune of Berkano, Rune of Hagalaz, Soul of Cain

    3 rooms: Rune of Algiz, Blank Rune, Soul of Magdalene, Soul of Judas, Soul of ???, Soul of the Lost

    4 rooms: Rune of Ehwaz, Rune of Perthro, Black Rune, Soul of Isaac, Soul of Eve, Soul of Eden, Soul of the Forgotten, Soul of Jacob and Esau

    6 rooms: Rune of Dagaz, Soul of Samson, Soul of Azazel, Soul of Apollyon, Soul of Bethany

    12 rooms: Rune of Jera, Soul of Lilith, Soul of the Keeper

      Type: Active

      Recharge time: Varies

      Item Pool: Secret Room, Crane Game

    * Secret Room

  • Mucormycosis

    ItemID: 553

    "Spore shot"

    Quality: 3

    Tears have a chance to fire a fungus tear that sticks to enemies. It grows rapidly in size then explodes into a gas cloud that damages nearby enemies

    When the explosion happens, more homing fungus tears fire out in random directions. Those tears will cause the same effect if they happen to hit other enemies

    Effects that replace your tears such as Brimstone simply have a chance to apply this effect

      Type: Passive

      Item Pool: Item Room

    *,

  • 2Spooky

    ItemID: 554

    "4me"

    Quality: 2

    Any enemies that come within close range of Isaac will become feared, which causes them to flee

      Type: Passive

      Item Pool: Devil Room

    *,

  • Golden Razor

    ItemID: 555

    "Pain from gain"

    Quality: 2

    +5 coins when picked up

    When used, this item takes away 5 of your coins and gives a +1.2 Damage Up that lasts for the current room

    Can stack as many times as you want. Using it with less than 5 coins does nothing

    UNLOCK: Unlock this item by collecting 99 coins then spending all of them in the same run

      Type: Active

      Recharge time: Instant

      Item Pool: Item Room, Greed Mode Item Room

    *,

  • Sulfur

    ItemID: 556

    "Temporary demon form"

    Quality: 2

    Upon use, grants use of Brimstone for the current room

    If used twice in the same room, the brimstone laser becomes massive and deals +1.8 more damage

    Using it more than twice in the same room will give a damage increase each time

      Type: Active

      Recharge time: 3 rooms

      Item Pool: Devil Room

    *,

  • Fortune Cookie

    ItemID: 557

    "Reusable fortunes"

    Quality: 2

    Upon use, displays a random fortune and has a chance to drop either a soul heart, a card (including dice shards), rune/soul stone or a trinket

    Soul hearts and tarot cards are much more common than trinkets

      Type: Active

      Recharge time: 2 rooms

      Item Pool: Item Room

    *,

  • Eye Sore

    ItemID: 558

    "More eyes"

    Quality: 2

    With each tear fired, you have a chance to fire 1-3 extra tears in random directions

    The extra tears scale with your other damage increasing items

    Synergises with other items that replace your tears, like Brimstone or Technology

    The chance to fire extra tears is not affected by luck

      Type: Passive

      Item Pool: Item Room

    *,

  • 120 Volt

    ItemID: 559

    "Zap!"

    Quality: 3

    This item will fire electricity at nearby enemies, dealing roughly x0.75 of your tear damage rapidly

    The electricity can chain up to 4 enemies if they are close enough

    On floors with water on the ground (Downpour, Flooded Caves, Dross) this effect chain onto enemies further away than it normally would

      Type: Passive

      Item Pool: Item Room

    *,

  • It Hurts

    ItemID: 560

    "No it doesn't..."

    Quality: 1

    Taking damage causes Isaac to fire a circle of 10 tears around him, each dealing 10 damage

    After taking damage, you also gain a +1.2 Tears Up for the rest of the current room. Any subsequent hits give +0.4 Tears Up and will ignore the normal fire rate cap

      Type: Passive

      Item Pool: Item Room

    *,

  • Almond Milk

    ItemID: 561

    "DMG down + tears up + you feel nutty"

    Quality: 1

    Greatly increases tears (x4 fire rate)

    Greatly decreases damage (x0.33 damage multiplier)

    Individual tears gain random worm effects (e.g. Hook Worm, Wiggle Worm etc.)

      Type: Passive

      Item Pool: Item Room

    *,

  • Rock Bottom

    ItemID: 562

    "It's only up from there"

    Quality: 2

    Prevents your stats from being reduced any more for the rest of the run

    e.g. Stat Down pills do nothing, and items like Experimental Treatment increase stats but don't reduce any

    This effect works on items that apply negative stat modifiers, such as Soy Milk

    This effect works for anything that gives temporary buffs, like Devil/Strength cards, or kill bonuses like Bloody Lust

    If you somehow lose Rock Bottom, your stats will go back to normal

    UNLOCK: Unlock this item by defeating the Boss Rush as Jacob & Esau

      Type: Passive

      Item Pool: Secret Room

    *,

  • Nancy Bombs

    ItemID: 563

    "Random blast +5 bombs"

    Quality: 1

    +5 Bombs

    Bombs now explode with a random effect (e.g. Poison, Homing, Prize Bombs)

    In Antibirth this was called Enigma Bombs

      Type: Passive

      Item Pool: Item Room

    *,

  • A Bar of Soap

    ItemID: 564

    "Tears + shot speed up"

    Quality: 3

    +0.5 Tears Up

    +0.2 Shot Speed Up

      Type: Passive

      Item Pool: Boss Room

    *,

  • Blood Puppy

    ItemID: 565

    "What a cute little thing!"

    Quality: 2

    Spawns a red worm familiar that chases enemies nearby around the room and deals 2 contact damage per tick

    After killing a 15 enemies, Blood Puppy transforms into an aggressive version that will also attack Isaac by charging at him. Damaging the aggressive Blood Puppy will eventually return it to its normal state.

    While aggressive, Blood Puppy deals 7.5 damage and drops half a red heart for every 10 enemies it kills.

    After killing a 25 more enemies, it transforms again dealing 15 damage and destroying obstacles it charges into. Isaac takes a full heart if hurt by Blood Puppy and it drops a full red heart for every 10 enemies it kills.

    UNLOCK: Unlock this item by defeating Mother in the Corpse II as Lilith

      Type: Passive, Familiar

      Item Pool: Item Room, Red Chest, Curse Room

    *,

  • Dream Catcher

    ItemID: 566

    "Sweet dreams"

    Quality: 2

    During the transition between floors, this item shows you a preview of the item that will spawn in the item room, and the boss that will appear

    Gives +1 Soul Heart when starting each new floor after picking this up

    Hidden question mark items will be revealed, even if you have Curse of the Blind

    On XL floors both items are shown

      Type: Passive

      Item Pool: Shop

    *,

  • Paschal Candle

    ItemID: 567

    "Keep the flame burning"

    Quality: 3

    Gives +0.4 Tears Up for each room completed without taking damage, up to a maximum of +2.0 Tears Up

    When you take damage, the tears bonus is reset

    Picking this item up counts and gives you a temporary +0.4 Tears Up as well

      Type: Passive

      Item Pool: Angel Room

    *,

  • Divine Intervention

    ItemID: 568

    "Double tap shield"

    Quality: 2

    Allows you to double-tap the shoot button to create a holy shield for 1 second that pushes enemies back and deals 10 damage to them if they touch it

    The shield also reflects enemy shots and beams back at them for some extra damage

    Can only be activated every 3 seconds (Shown by a white glow and a ticking noise)

    UNLOCK: Unlock this item by defeating Hush as Bethany

      Type: Passive

      Item Pool: Angel Room

    *,

  • Blood Oath

    ItemID: 569

    "Bleed me dry"

    Quality: 2

    At the beginning of each new floor, this item will stab Isaac and reduce your red health down as much as it can without killing you. In exchange it gives you +0.05 Speed Up and Damage Up for every half a heart this item removes

    The amount of Damage Up is (0.15 * FullHeartsRemoved ^ 2)

    If Isaac is already at half a red heart when stabbed, no damage or speed increases are given

    The damage from being stabbed can be avoided with invincibility, however no damage or speed stat increases are gained if you do

      Type: Passive

      Item Pool: Devil Room, Curse Room

    *,

  • Playdough Cookie

    ItemID: 570

    "Tasty rainbow"

    Quality: 3

    Your individual tears each gain a random effect from either: Poison, Fear, Slow, Freeze, Charm, Burning, Homing, Bleeding, x2 Damage or Reduced damage

      Type: Passive

      Item Pool: Item Room

    *,

  • Orphan Socks

    ItemID: 571

    "Speed up + your feet feel stronger"

    Quality: 1

    +2 Soul Hearts

    +0.3 Speed Up

    Allows you to walk on harmful floor effects without taking damage (e.g. spikes, creep). Doesn't include Curse Room doors or spiked rocks

      Type: Passive

      Item Pool: Secret Room

    *,

  • Eye of the Occult

    ItemID: 572

    "DMG up + range up + controlled tears"

    Quality: 3

    Tears can be controlled mid-flight using the directional keys

    +1 Damage Up

    +2.0 Range Up

    -0.16 Shot Speed Down

      Type: Passive

      Item Pool: Devil Room

    *,

  • Immaculate Heart

    ItemID: 573

    "Halo of tears"

    Quality: 3

    In addition to regular tears, Isaac will sometimes fire extra spectral tears that orbit around him

    +1 HP Up

    +20% damage multiplier (x1.2)

    Fully heals all your red heart containers

      Type: Passive

      Item Pool: Angel Room

    *,

  • Monstrance

    ItemID: 574

    "Purifying light"

    Quality: 2

    Isaac now emits a large light aura that damages nearby enemies 5 times per second while touching it

    The visual effect is similar to the effect given to tears by the GodHead item

    The aura deals more damage towards the center, ranging from 0.75 at max range to 4 damage when touching Isaac

      Type: Passive

      Item Pool: Angel Room

    *,

  • The Intruder

    ItemID: 575

    "Invasive friend"

    Quality: 3

    In addition to normal tears, Isaac now also fires a set of 4 quadshot tears with a slowing effect

    The quadshot tears deal 1.5 damage each and do not scale with your damage upgrades

    Upon taking damage, you have a chance to dislodge the spider from your face. It leaps at enemies, dealing contact damage and firing quad shots at them for the rest of the room

    Counts as 1 of 3 spider items needed towards the Spider Baby transformation.

      Type: Passive

      Item Pool: Item Room

    *, ew gross face spider in face

  • Dirty Mind

    ItemID: 576

    "Filthy friends"

    Quality: 2

    Each time you destroy a poop, this item will spawn 1-4 friendly Dip familiars that follow you, block shots and attack nearby enemies

    Different poop types will spawn different types of Dip, each with their own effect

    Golden poop dips can petrify enemies, turning them to gold for a few seconds. If the enemy dies while in this state they will drop 1-4 coins

    Corn poop dips spawn 1 blue fly on death

    Rainbow poop Dips charm enemies and have a chance to spawn 1/2 a red heart on death

    Black poop Dips leave a trail of creep

    White poop Dips have a small Hallowed Ground aura effect, increasing your damage and fire rate while standing in it.

    All enemy dips become friendly.

    UNLOCK: Unlock this item by defeating challenge #36 (Scat Man)

      Type: Passive

      Item Pool: Item Room

    *,

  • Damocles

    ItemID: 577

    "A king's fortune... but at what cost?"

    Quality: 2

    When used, places a sword directly above Isaac's head and while active, will spawn an extra item for every item pedestal spawned

    After getting hit once with the item activated, at any time without warning, the sword may fall, instantly killing Isaac regardless of his health

    After being hit the sword has a 1/10000 chance every 4 frames to fall. This chance doesnt change if you take further damage

    You effectively have a 4.4% chance for every minute that passes after taking damage to die

    Self-inflicted damage i.e. Curse Rooms and Blood Donation Machines don't trigger this effect

    Items with a price will spawn the extra item free of charge (i.e. in shops or devil rooms)

    The only way to survive the falling sword is either through extra lives, by using items that would make you invincible, such as Gnawed Leaf or playing as The Lost. After the sword falls, extra items will no longer spawn

    UNLOCK: Unlock this item by defeating The Lamb as Jacob & Esau

      Type: Active

      Recharge time: One time use

      Item Pool: Devil Room, Secret Room

    *,

  • Free Lemonade

    ItemID: 578

    "Party time!"

    Quality: 2

    Upon use, spawns a giant puddle of lemonade that deals 6 damage per tick to any enemies which come in contact with it

    A similar effect to the Lemon Party pill

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Item Room

    *,

  • Spirit Sword

    ItemID: 579

    "Divine blade"

    Quality: 3

    Your tears are replaced with a sword which can be swung to deal damage (Damage * 3 + Base Damage)

    Holding the fire button charges a spin attack (Damage * 8 + 10). The charge time is based on your tears stat.

    While at full red health you also shoot a projectile across the room with each swing, dealing your current Damage + 2 (similar to the Master Sword in Zelda)

    UNLOCK: Unlock this item by defeating challenge #39 (Isaac's Awakening)

      Type: Passive

      Item Pool: Angel Room

    *,

  • Red Key

    ItemID: 580

    "Explore the other side"

    Quality: 3

    While held, a red outline of a door will appear on certain walls. Using the Red Key near it will spawn a red room

    This room will randomly choose from many types, including (but not limited to) any regular room from that floor, treasure rooms, curse rooms, devil rooms, angel rooms, I AM ERROR rooms and more

    In rooms with multiple door outlines, the closest one will be opened

    Attempting to create a room outside the maximum boundary (13 x 13 rooms) of the map will take you to an I AM ERROR room. You can't use the Red Key to leave this room

    The Red Key can be used to open the secret room in the Home floor, which is the method for unlocking alternative 'Tainted' characters

    UNLOCK: Unlock this item by opening Mom's Box in the Home floor

      Type: Active

      Recharge time: 3 rooms

      Item Pool: Secret Room, Red Chest, Curse Room, Key Beggar, Mom's Chest

    *,

  • Psy Fly

    ItemID: 581

    "Flamboyant protector"

    Quality: 3

    Gives Isaac an orbital fly, that will rapidly charge around and deflect any incoming tears that would hit Isaac.

    It isn't 100% effective but the effect is very strong and will deflect most shots under a bullet hell situation.

    Deflected tears turn into homing tears and fire back at enemies, dealing 2 damage.

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation.

      Type: Passive, Familiar

      Item Pool: Item Room, Key Beggar

    *,

  • Wavy Cap

    ItemID: 582

    "Tears up. A mind changing experience!"

    Quality: 1

    Every time you use Wavy Cap, it gives +0.75 Tears Up and -0.03 Speed Down

    Also when used, this item will distort the screen and sound slightly, stacking every time you use it

    All of these effects stack for the rest of the floor, meaning if used too many times the screen will be distorted so much it becomes unplayable

    Each room you clear removes one use worth of effect - reducing the screen distortion slightly and giving +0.06 Speed Up and -0.3 Tears Down

    This item was called Black Mushroom in Antibirth

    Counts as 1 of 3 mushroom items needed towards the Fun Guy transformation.

      Type: Active

      Recharge time: Starts at 1 second, increasing by every time you use it. After 10 uses it stops auto recharging.

      Item Pool: Secret Room

    *,

  • Rocket in a Jar

    ItemID: 583

    "Rocket propulsion +5 bombs"

    Quality: 2

    +5 Bombs

    Placing a bomb while moving will fire an explosive rocket in the direction you're facing.

    Placing a bomb while standing still will place a regular bomb.

      Type: Passive

      Item Pool: Item Room, Bomb Beggar

    *,

  • Book of Virtues

    ItemID: 584

    "Spiritual companionship"

    Quality: 3

    Upon use, spawns a flame familiar that fires spectral tears and deals contact damage to enemies. After taking two hits, the fire will be extinguished

    The Book can be held at the same time as another active item. When used, this will combine with your other active item, creating a unique flame and possibly giving special effects

    The recharge time of this item is based on your 2nd active item, otherwise it's 4 rooms

    While held, guarantees the first Devil/Angel Room encountered to be an Angel Room, and increases the overall chance of getting one

    A maximum of 16 flames can be active at one time around Isaac

    Counts as 1 of 3 book items needed towards the Bookworm transformation

    UNLOCK: Unlock this item by defeating Isaac as Bethany

      Type: Active/Passive Item

      Recharge time: Varies

      Item Pool: Angel Room, Library

    *,

  • Alabaster Box

    ItemID: 585

    "A sacred offering"

    Quality: 2

    A single use active item that will spawn 3 soul hearts and 2 items from the Angel Room pool

    Starts fully uncharged and gains charges only through picking up soul and black. (6 full hearts to fully charge)

    Unless fully charged, hearts picked up are consumed by the Alabaster Box, instead of being added to your life total

    If a devil deal was already taken this run, it spawns 2 soul hearts and 1 Angel Room item instead.

    UNLOCK: Unlock this item by defeating The Lamb as Bethany

      Type: Active

      Recharge time: 12 charges (one time use)

      Item Pool: Shop

    *,

  • The Stairway

    ItemID: 586

    "Stairway to heaven"

    Quality: 3

    Spawns a ladder in the starting room of all future floors, which leads to an Angel Room

    Angel rooms accessed by The Stairway are different - They sell angel room items and soul hearts for money, similar to the Shop

    Pedestal items cost 15c, all other items (eternal/soul hearts, keys and holy cards) cost 5c. Sales can be randomly applied just like regular shops

    The ladder disappears after leaving the starting room, even if you haven't used it yet

    In Antibirth this was called Jacob's Ladder, which had to be renamed as Afterbirth+ already had an item with this name

    UNLOCK: Unlock this item by defeating Isaac as Jacob & Esau

      Type: Passive

      Item Pool: Angel Room

    *,

  • Sol

    ItemID: 588

    "Radiant victory"

    Quality: 2

    Permanently shows the location of the boss room on the map

    After defeating the shown boss fight, this item will activate a use of the Sun card (full heal and map reveal), fully recharge your active item, remove curses from the floor, gives +3 Damage Up and +1 Luck up for the rest of the floor

    Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped)

    In The Void floor it shows a random boss room, which isn't necessarily Delirium's room

      Type: Passive

      Item Pool: Planetarium

    *,

  • Luna

    ItemID: 589

    "More secrets"

    Quality: 2

    Adds one extra secret room and one extra super secret room to each floor

    Each secret room contains a beam of light, that gives half a soul heart, and a Tears Up for the rest of the floor. These stack with multiple secret rooms - The first one gives +1.00 Tears Up, then all future ones give +0.5 and half a soul heart each.

    Reveals the location of one secret room on the minimap.

    Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped)

      Type: Passive

      Item Pool: Planetarium

    *,

  • Mercurius

    ItemID: 590

    "Speed up + you feel elusive"

    Quality: 3

    +0.40 Speed Up

    Doors remain open when entering a room with enemies in it. This means you can leave rooms before defeating the enemies inside

    Doesn't open locked doors, or the door that leads to the Boss Room

    Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped)

      Type: Passive

      Item Pool: Planetarium

    *,

  • Venus

    ItemID: 591

    "HP up + you feel pretty"

    Quality: 1

    +1 HP Up

    This item causes nearby enemies to be affected by the charm effect, causing them to attack other nearby enemies

    The charm effect will wear off very quicky when enemies move away from Isaac

    Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped)

      Type: Passive

      Item Pool: Planetarium

    *,

  • Terra

    ItemID: 592

    "Born to rock"

    Quality: 3

    This item causes your tears to become rocks, which have increased knockback and can break other rocks and objects

    +1.0 Damage Up, but each tear has a random damage modifier that can go up or down

    Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped)

      Type: Passive

      Item Pool: Planetarium

    *,

  • Mars

    ItemID: 593

    "Double tap dash"

    Quality: 2

    Allows Isaac to charge by double tapping the same direction, dealing damage to any enemies caught

    You are invincible while charging

    Can be used multiple times per room

    The dash deals x4 your current tear damage

    Doesn't have to be in a straight line, you can hold another button to curve it

    Has a 3 second cooldown before it can be used again

    Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped)

      Type: Passive

      Item Pool: Planetarium

    *,

  • Jupiter

    ItemID: 594

    "You're a gas giant!"

    Quality: 3

    Gives +0.2 Speed Up, but every time you move your speed rapidly goes down by -0.5. While your speed is decreasing, Isaac will fart around the room, spawning poison gas clouds

    The farts stop spawning once you reach the minimum movement speed caused by this item

    Poison deals damage equal to half your tears

    Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped)

      Type: Passive

      Item Pool: Planetarium

    *,

  • Saturnus

    ItemID: 595

    "Ring of tears"

    Quality: 1

    Gives you a wide aura which grants 7 orbital tears upon entering a new room

    The tears orbit for 13 seconds before dropping off

    Has a chance to absorb any enemy tears and add them to the orbiting tears. They can be used to damage enemies

    Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped)

      Type: Passive

      Item Pool: Planetarium

    *,

  • Uranus

    ItemID: 596

    "Ice tears"

    Quality: 3

    Isaac now shoots ice tears that slow enemies. Enemies that are killed by the ice tears will become frozen

    Frozen enemies never unfreeze and are considered dead by the game. Kicking a frozen enemy will push it into the wall, where it shatters and fires ice shards everywhere (these can then freeze other enemies)

    Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped)

      Type: Passive

      Item Pool: Planetarium

    *,

  • Neptunus

    ItemID: 597

    "Open the floodgates"

    Quality: 3

    Isaac will now automatically charge up tears, allowing you to store them up and fire them rapidly for a short time

    Any time you aren't firing tears, the charge bar will start filling up, for up to 3 seconds. Holding down the fire button again will quickly release all stored teared

    Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped)

      Type: Passive

      Item Pool: Planetarium

    *,

  • Pluto

    ItemID: 598

    "Size down"

    Quality: 3

    +0.72 Tears Up

    Greatly reduce Isaac's size, to an extent where enemy tears will now travel straight over him without dealing damage if you're standing close enough. Tears can still hit Isaac if gravity applies for too long

    Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped)

      Type: Passive

      Item Pool: Planetarium

    *,

  • Voodoo Head

    ItemID: 599

    "Extra curse rooms"

    Quality: 1

    This item has a chance to spawn additional curse rooms on each future floor

      Type: Passive

      Item Pool: Shop, Crane Game

    *,

  • Eye Drops

    ItemID: 600

    "Tears up"

    Quality: 3

    +0.55 Tears Up

    Each of Isaac's eyes now fires at differing rates, giving an overall increase to rate of fire

      Type: Passive

      Item Pool: Boss Room

    *, bottle container dropper medicine

  • Act of Contrition

    ItemID: 601

    "Tears up, you feel forgiven"

    Quality: 3

    +1 Eternal Heart

    +0.7 Tears Up

    Allows Angel Rooms even if a Devil deal has been taken before

      Type: Passive

      Item Pool: Angel Room

    *,

  • Member Card

    ItemID: 602

    "Exclusive access!"

    Quality: 1

    All shops now contain a trapdoor with a ladder, which leads down to a special shop

    The special shop contains various consumables and items at a higher price which are not necessarily from the normal Shop item pool

    Items cost 20c, trinkets cost 15c, consumables cost 7c

    UNLOCK: Unlock this item by spending 40+ coins in the same shop

      Type: Passive

      Item Pool: Shop

    *, gold

  • Battery Pack

    ItemID: 603

    "Instant energy!"

    Quality: 1

    When picked up, this item fully recharges your currently held active item and drops between 2-4 battery pickups. These can be smaller or big batteries

      Type: Passive

      Item Pool: Shop, Battery Beggar

    *,

  • Mom's Bracelet

    ItemID: 604

    "Mother's strength"

    Quality: 2

    Upon use, Mom's Bracelet allows you to grab objects in the room and throw them, damaging any enemies which are hit

    Objects include pots, rocks etc

    Allows you to remove the skull on top of Host enemies, turning them into the red version

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Active

      Recharge time: 1 second

      Item Pool: Shop, Crane Game, Mom's Chest

    *,

  • The Scooper

    ItemID: 605

    "Plop!"

    Quality: 0

    When used, this item spawns a Peeper familiar for the current room, which deals 12 contact damage per tick to enemies and leaves red creep in its path

    Using this item removes Isaac's right eye, causing tears from this eye to deal x1.5 your normal tear damage

      Type: Active

      Recharge time: 3 rooms

      Item Pool: Item Room

    *,

  • Ocular Rift

    ItemID: 606

    "Stare into the abyss"

    Quality: 3

    Fired tears now have a chance to summon a rift when they land on the ground

    The spawned rift sucks in enemies, projectiles and pickups and deals damage to enemies caught inside

    The size of the rift scales with your tear damage

    In Antibirth this item was called Oculus Rift

      Type: Passive

      Item Pool: Devil Room

    *,

  • Boiled Baby

    ItemID: 607

    "Messy friend"

    Quality: 1

    A familiar boil that randomly fires bursts of tears, similar to the Boil enemy

      Type: Passive, Familiar

      Item Pool: Item Room/p>

    *,

  • Freezer Baby

    ItemID: 608

    "Iced iced baby"

    Quality: 2

    A familiar baby that fires tears which have a chance to freeze or petrify enemies

    Frozen enemies never unfreeze and are considered dead by the game. Kicking a frozen enemy will push it into the wall, where it shatters and fires ice shards everywhere (these can then freeze other enemies)

    Counts as 1 of 3 familiar items needed towards the Conjoined transformation

      Type: Passive, Familiar

      Item Pool: Item Room

    *,

  • Eternal D6

    ItemID: 609

    "???"

    Quality: 2

    Upon use this item acts identical to the D6 item, however the item also has a 50% chance to disappear

    In the game files this item is called 'Florians Dice', which is a reference to the Eternal update for the original Binding of Isaac game, which changed the D6 to act as this item does

    UNLOCK: Unlock this item by defeating Mother in the Corpse II as ???

      Type: Active

      Recharge time: 2 rooms

      Item Pool: Item Room, Secret Room, Crane Game

    *,

  • Bird Cage

    ItemID: 610

    "Fat buddy"

    Quality: 1

    Taking damage for the first time in a room spawns a familiar which targets an enemy and jumps on them, releasing a rock wave outwards

    For the remainder of the room the familiar then continues to attack enemies similar to the Dead Bird item

    UNLOCK: Unlock this item by defeating Mother in the Corpse II as Eve

      Type: Passive

      Item Pool: Item Room

    *,

  • Larynx

    ItemID: 611

    "Hear my pain"

    Quality: 2

    When used, this item does a shout-type attack, with its effect increasing in damage and size the more charges you have

    Larynx can be used with any number of charges. At 1 charge it deals 48 damage to any enemies close to Isaac. At the full 12 charges Isaac does a massive shout, dealing 356 damage to all enemies on the screen

    UNLOCK: Unlock this item by defeating The Beast as Tainted Samson

      Type: Active

      Recharge time: 12 rooms (Can be used with partial charges)

      Item Pool: Item Room, Greed Mode Item Room

    *,

  • Lost Soul

    ItemID: 612

    "Protect him"

    Quality: 2

    This item gives you a familiar version of The Lost character which dies instantly upon hit

    If the familiar survives an entire floor you get one of: 3 soul hearts, 2 eternal hearts or a random item/angel room item

    Regenerates at the start of each floor if dead

    UNLOCK: Unlock this item by defeating Mother in the Corpse II as The Lost

      Type: Passive, Familiar

      Item Pool: Item Room, Secret Room

    *,

  • Blood Bombs

    ItemID: 614

    "Bloody blast + HP up"

    Quality: 1

    +1 HP Up

    Restores 5 empty red heart containers

    Bombs now spawn a puddle of red creep upon explosion

    While at 0 bombs, you can also place further bombs now at the cost of 1/2 of a heart. This will kill The Lost if used

      Type: Passive

      Item Pool: Item Room

    *,

  • Lil Dumpy

    ItemID: 615

    "Puffy buddy"

    Quality: 0

    A familiar that floats around and farts when touched by an enemy, which deals damage to nearby enemies and confuses them for a few seconds

      Type: Passive

      Item Pool: Item Room

    *,

  • Bird's Eye

    ItemID: 616

    "It burns"

    Quality: 2

    You have a chance alongside each tear to shoot a red flame, which deals damage to enemies that come in contact with it

    Damage starts at x4 your current tear damage, and scales down each time an enemy touches the fire

    The chance to create a fire scales with your Luck stat, at +11 Luck you shoot one with every tear

      Type: Passive

      Item Pool: Item Room

    *,

  • Lodestone

    ItemID: 617

    "Magnetizing tears"

    Quality: 3

    Tears now have a chance to cause enemies to be magnetized,

    Magnetized enemies attract other enemies, tears (including Isaac's) and enemy projectiles,

      Type: Passive

      Item Pool: Item Room, Crane Game

    *,

  • Rotten Tomato

    ItemID: 618

    "Delicious!"

    Quality: 1

    You have a chance to fire a tear that marks enemies red

    Marked enemies will be attacked by other enemies either until it is killed or it kills all the other enemies attacking it

    Chance to fire a marking tear scales with your luck stat

      Type: Passive

      Item Pool: Item Room, Rotten Beggar

    *,

  • Birthright

    ItemID: 619

    "???"

    Quality: 2

    This item has a different effect for each character. See next icon for Tainted character effects

    Isaac - All items cycle through two options

    Maggy - Not yet implemented

    Cain - Not yet implemented

    Judas - Not yet implemented

    ??? - Every HP upgrade is now worth 2 soul hearts

    Eve - Whore of Babylon and Dead Birds effects are always active

    Samson - Bloody Lust can gain 4 more damage boosts, for a new max total of +14 Damage

    Azazel - His beam becomes much wider, no effect on damage

    Lazarus - When Lazarus dies for the first time, gives +21.6 Damage Up, slowly fading over time.

    Eden - Spawns 3 items from any pools, you can only pick 1

    The Lost - Useless items like HP upgrades, spectral tears or flight are removed from the item pools

    Lilith - Not yet implemented

    Keeper - Not yet implemented

    Apollyon - Not yet implemented

    The Forgotten - Your Soul is now unchained and free to move.

    Bethany - Activating an item using soul charges is sometimes free

    Jacob & Esau - The character who picks up the item gains copies of three of the other charcter's passive items

    UNLOCK: Unlock this item by defeating ??? as Jacob & Esau

      Type: Passive

      Item Pool: Shop

    *,

  • Birthright

    ItemID: 619

    "???"

    Quality: 2

    This item has a different effect for each character. See previous icon for normal character effects

    Tainted Isaac - Adds 4 more spaces for items

    Tainted Maggy - Adds 1 extra real heart container that doesn't deplete

    Tainted Cain - Doubles picks dropped when touching an item

    Tainted Judas - Not yet implemented

    Tainted ??? - Allows you to hold up to 29 poops

    Tainted Eve - Not yet implemented

    Tainted Samson - Chaining kills adds 3 seconds to the Berserk timer instead of 1

    Tainted Azazel - Doubles his sneeze size

    Tainted Lazarus - Not yet implemented

    Tainted Eden - Items taken before Birthright no longer get rerolled when taking damage

    Tainted Lost - Grants an extra life. Deals 200 damage to nearby enemies when reviving

    Tainted Lilith - Not yet implemented

    Tainted Keeper - Nearby coins dropped by enemies move towards you quickly

    Tainted Apollyon - Not yet implemented

    Tainted Forgotten - Grants the Recall ability. When used it sends the Forgotten skull back to you

    Tainted Bethany - Not yet implemented

    Tainted Jacob - Unknown

    UNLOCK: Unlock this item by defeating ??? as Jacob & Esau

      Type: Passive

      Item Pool: Shop

    *,

  • Red Stew

    ItemID: 621

    "Full HP + temporary DMG up"

    Quality: 0

    Fully heals all red heart containers

    Significantly increases damage (around +21), however the damage boost wears off slowly over time at a rate of roughly -0.04 per second

    Every enemy you kill adds +0.02 Damage to the timed effect of Red Stew

    UNLOCK: Unlock this item by defeating Satan as Jacob & Esau

      Type: Passive

      Item Pool: Shop

    *,

  • Genesis

    ItemID: 622

    "In the beginning"

    Quality: 2

    When used, removes all your passive items and teleports you to Isaac's Bedroom

    For every passive item removed, you are given a choice of 3 random pedestal items from any item pool. Essentially you are rerolling all your items, but each new item you get to choose between 3 random options

    The bedroom also contains a random trinket, 2 chests, 2 sacks and Isaac's bed, which can be used to full heal your red heart health

    The only way to exit Isaac's bedroom is teleporting out or via the trapdoor, which takes you to the next floor. This will deviate you from the alt path if you are currently on it

    UNLOCK: Unlock this item by defeating Greedier Mode as Jacob & Esau

      Type: Active

      Recharge time: One time use

      Item Pool: Devil Room, Greed Mode Angel Room

    *,

  • Sharp Key

    ItemID: 623

    "Open your enemies"

    Quality: 1

    +5 Keys

    Upon use, allows you to consume 1 key and fire it at an enemy, dealing significant damage

    The damage done by the key projectile pierces through enemies and scales with your damage upgrades

    Keys fired by this item can open doors, secret rooms and destroy objects in the room, such as rocks

    Cannot be used if you don't have any keys

      Type: Active

      Recharge time: Instant

      Item Pool: Shop

    *,

  • Booster Pack

    ItemID: 624

    "Collect them all!"

    Quality: 1

    Spawns 5 random tarot cards

      Type: Passive

      Item Pool: Boss Room, Shop

    *,

  • Mega Mush

    ItemID: 625

    "I'm a big boy now!"

    Quality: 4

    When used, this item causes Isaac to become humongous for 30 seconds

    While huge, Isaac is invincible and can crush objects, doors and enemies

    For the duration of the effect this gives you a x4 Damage Multiplier and +2.0 Range Up, but your rate of fire goes way down

    UNLOCK: Unlock this item by beating everything as every character on Hard Mode

      Type: Active

      Recharge time: 12 rooms

      Item Pool: Item Room

    *,

  • Knife Piece 1

    ItemID: 626

    "???"

    Quality: 0

    Combine with Knife Piece 2 to create a Knife which can be fired across the room, dealing 25 damage to any enemies it comes into contact with

    In the Downpour/Dross II, you will find a white flame somewhere, and a room with a mirror in it. Touching the white flame temporarily turns you into The Lost, but allows you to walk through the mirror into a mirrored version of this floor. You have the Holy Mantle effect to prevent one hit per room, but taking another hit will kill you. The Knife Piece 1 is located in the Item Room in the mirrored area. Returning back through the mirror door returns you back to normal again

    If you haven't unlocked Holy Mantle for The Lost yet, you won't gain the effect after touching a white fire so be careful!

    The mirrored floor rooms have respawned enemies, and allows you to optionally fight the Boss a second time for an extra item

    When combined with Knife Piece 2, can be used to stab the fleshy door in the Mausoleum II, which then leads to the Corpse floor and the Mother boss

      Type: Passive

      Item Pool: None (see above)

    *,

  • Knife Piece 2

    ItemID: 627

    "???"

    Quality: 0

    Combine with Knife Piece 1 to create a Knife which can be fired across the room, dealing 25 damage to any enemies it comes into contact with

    In the Mines/Ashpit II, there's a room with a minecart and a broken track. Pressing 3 yellow buttons on the floor causes the minecart to be rideable. Following the path takes you to an abandoned mineshaft, which leads you to a pedestal with the Knife Piece. Taking it will cause Mom's Shadow to spawn and chase you. You must make it back through the path solving a few bomb puzzles while avoiding her, to get back to the regular floor. All your items and consumables are temporarily removed while in the abandoned mine

    The room to access Knife Piece 2 only appears if you have Knife Piece 1 already

    You can skip pressing the 3 yellow buttons if you have the ability to fly and have 2 bombs to force open the door

    When combined with Knife Piece 1, can be used to stab the fleshy door in the Mausoleum II, which then leads to the Corpse floor and the Mother boss

      Type: Passive

      Item Pool: None (see above)

    *,

  • Death Certificate

    ItemID: 628

    "Where am I?"

    Quality: 4

    This is a one time use item that teleports you to an alternate floor, which contains every single item in the game

    The items are spread between several different rooms all on pedestals. You may take only one of the items, before being teleported back to where you were

    You may take only one of the items, before being teleported back to where you were

    It's literally every item, that includes items not in item pools life Knife Pieces

    UNLOCK: Unlock this item by completing every post-it note for every character, including the Tainted characters

      Type: Active

      Recharge time: 1 time use

      Item Pool: Secret Room

    *,

  • Bot Fly

    ItemID: 629

    "Defense drone"

    Quality: 3

    Gives you a robot fly familar that orbits around Isaac and fires shielded tears at incoming projectiles

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive, Familiar

      Item Pool: Item Room, Key Beggar, Crane Game

    *,

  • Meat Cleaver

    ItemID: 631

    "Slice but no dice"

    Quality: 1

    When used, the Meat Cleaver will split all enemies in the room into 2 smaller versions with ~40% health each

    For enemies that have multiple parts to them (e.g. Larry Jr.) it will split them into 2 smaller enemies with half the number of sections they used to have

    If the enemy normally has a mechanic that splits it (e.g. Teratoma, Envy) then Meat Cleaver will deal a lot of damage and trigger the splitting effect

    If the split enemy has low enough health, it will just die instead of splitting

    UNLOCK: Unlock this item by defeating Mother in the Corpse II as Isaac

      Type: Active

      Recharge time: 2 rooms

      Item Pool: Item Room

    *,

  • Evil Charm

    ItemID: 632

    "Luck up + you feel protected"

    Quality: 1

    +2 Luck Up

      Type: Passive

      Item Pool: Secret Room

    *,

  • Dogma

    ItemID: 633

    "Ascended"

    Quality: 0

    +0.1 Speed Up

    +2.0 Damage Up

    Grants you the ability to fly

    This item isn't available in any item pools - you are automatically given it after defeating Dogma, just before The Beast sequence

      Type: Passive

      Item Pool: None

    *, godma

  • Purgatory

    ItemID: 634

    "Help from beyond"

    Quality: 2

    While in a room with enemies, red cracks will appear on the floor in random locations

    Walking over the crack spawns a white soul familiar, that launches itself into the nearest enemy, exploding and dealing double your tear damage to everything near it

    Cracks will keep appearing but only one can exist in the room at a time

    UNLOCK: Unlock this item by defeating challenge #38 (Baptism by Fire)

      Type: Passive

      Item Pool: Devil Room, Angel Room

    *,

  • Stitches

    ItemID: 635

    "Bait and switch"

    Quality: 1

    While held, this item spawns a familiar that can be moved around using the arrow keys and deals 1.5 damage per tick to any enemies it touches

    When activated, you teleport, swapping places with wherever Stitches was positioned

    If used while stitches is on top of an enemy, it an be used to telefrag enemies, dealing a lot of damage

      Type: Active, Familiar

      Recharge time: 3 seconds

      Item Pool: Item Room

    *,

  • R Key

    ItemID: 636

    "Time to start over"

    Quality: 4

    When used, this item restarts the game and places you back on the first floor with all your currently collected items, similar to doing a Victory Lap

    The game timer does not reset

    Allows angel rooms to be found in the new run if a devil deal was taken in the first run

    In Greed Mode this item costs 99 coins

    Donation machines remain jammed if they were before using the R Key

      Type: Active

      Recharge time: Single use

      Item Pool: Secret Room

    *,

  • Knockout Drops

    ItemID: 637

    "They pack a punch!"

    Quality: 3

    Isaac now has a chance to fire a fist instead of normal tears, which have a much higher knockback effect and confuse enemies for a few seconds

    Enemies that are knocked back will damage and knock back any enemy they are knocked into

      Type: Passive

      Item Pool: Item Room

    *,

  • Eraser

    ItemID: 638

    "Erase thy enemy"

    Quality: 2

    An active item that allows you to throw an eraser at any enemy, which will kill it and prevent it from appearing for the rest of the run

    Enemies that are erased create a puff of smoke instead of spawning

    Works on bosses, except it doesn't kill them it just deals 15 damage

    Can only be used once per floor - batteries also cannot be used to recharge it to bypass this restriction

    The first use will raise it above your head, then by pressing the fire button it will be thrown in that direction

      Type: Active

      Recharge time: 1 room (Can only be used once per floor)

      Item Pool: Shop, Crane Game

    *,

  • Yuck Heart

    ItemID: 639

    "Gross!"

    Quality: 3

    When used, this item will give you +1 Rotten Heart

    Rotten Hearts act as red hearts and each one you currently have spawns 2 blue flies upon successfully clearing a room

    UNLOCK: Unlock this item by defeating Mother in the Corpse II as Maggy

      Type: Active

      Recharge time: 6 rooms

      Item Pool: Item Room, Rotten Beggar

    *,

  • Urn of Souls

    ItemID: 640

    "Unleash their sorrow"

    Quality: 3

    Enemies now create a soul upon death, which is automatically sucked into the Urn giving it +1 charge. Mini-bosses and bosses create 2-3 souls

    When activated, the urn can be fired as a high damage flamethrower in any direction

    A charge is consumed roughly every 0.5 seconds of use

    Multi-part enemies such as Envy or Teratoma create a soul per each part killed

    A maximum of 20 souls can be held in the urn at one time

    UNLOCK: Unlock this item by beating Satan as Bethany

      Type: Active

      Recharge time: None (see above)

      Item Pool: Angel Room

    *,

  • Akeldama

    ItemID: 641

    "Spill your guts"

    Quality: 2

    With each shot fired, another bloody tear will spawn behind Isaac

    Spawning multiple tears will form a trail of tears that follow Isaac as he moves, bursting and dealing damage upon contact with enemies

    The effect from this item will only work while in a hostile room that contains at least 1 enemy

    UNLOCK: Unlock this item by defeating Mother in the Corpse II as Judas

      Type: Passive

      Item Pool: Item Room

    *,

  • Magic Skin

    ItemID: 642

    "All your desires fulfilled"

    Quality: 2

    Upon use, this item consumes 1 heart container or 2 soul hearts and spawns one item pedestal from the current room's pool

    Every use gives a broken heart, meaning that slot is permanently broken and the maximum health limit is reduced by 1 for the rest of the run

    After 12 uses, Isaac dies instantly (this also applies to The Lost despite having no health)

    Magic Skin will continue to appear after finding it once if you are not still holding it - the chance for it to replace an item is 1 ÷ (12 - number of times used) up to a maximum of 50%

    UNLOCK: Unlock this item by defeating Mother in the Corpse II as Jacob & Esau

      Type: Active

      Recharge time: 6 rooms

      Item Pool: Shop, Red Chest, Curse Room

    *,

  • Revelation

    ItemID: 643

    "Awaken your faith"

    Quality: 4

    +2 Soul Hearts

    Grants you the ability to fly

    Holding the fire button charges up a light beam attack similar to Brimstone

    The light beam deals damage equal to your current tear damage per tick to any enemies touching it

    UNLOCK: Unlock this item by defeating Mother in the Corpse II as Bethany

      Type: Passive

      Item Pool: Angel Room

    *,

  • Consolation Prize

    ItemID: 644

    "+1 to lowest stat"

    Quality: 1

    When picked up, this item raises your lowest stat or gives you some of whichever consumable item is the lowest (+3 coins or +1 bomb or +1 key)

    Drops either a bomb, a key or 3 coins on the ground. This is decided by whatever you have the least of. Keys and bombs are equal to 3 coins for deciding which to give

      Type: Passive

      Item Pool: Boss Room, Golden Chest, Crane Game

    *,

  • Tinytoma

    ItemID: 645

    "Itching for revenge"

    Quality: 1

    Grants a large orbital that rotates around Isaac

    When the orbital takes a few hits, they split into two smaller ones

    After the smaller orbitals take another hit, they explode into 2 blue spiders

    This item will respawn after a period of time

    UNLOCK: Unlock this item by defeating Mother in the Corpse II as Lazarus

      Type: Passive, Familiar

      Item Pool: Item Room

    *,

  • Brimstone Bombs

    ItemID: 646

    "Demon blast +5 bombs"

    Quality: 3

    +5 Bombs

    Your bombs now explode and fire 4 Brimstone lasers in all cardinal directions

    Each brimstone laser deals 8 damage per tick for 13 total hits

    UNLOCK: Unlock this item by killing Hornfel before he can escape after breaking his minecart

      Type: Passive

      Item Pool: Devil Room, Bomb Beggar, Greed Mode Devil Room

    *,

  • 4.5 Volt

    ItemID: 647

    "Beat the juice out of them!"

    Quality: 2

    Active items no longer charge up as normal from clearing rooms

    Enemies taking damage now charges your item instead. This includes damage you deal, and environmental damage they take e.g. from Fireplaces

      Type: Passive

      Item Pool: Shop, Battery Beggar

    *,

  • Fruity Plum

    ItemID: 649

    "Bouncy friend"

    Quality: 1

    Gives you a familiar which is a smaller version of the Plum boss, which sprays tears and propels itself around the room

    Deals contact damage to any enemies it runs into

    UNLOCK: Unlock this item by beating Baby Plum 10 times

      Type: Passive, Familiar

      Item Pool: Item Room, Key Beggar

    *, extremely cute omg :plumsmug:

  • Plum Flute

    ItemID: 650

    "Play time!"

    Quality: 2

    When used, this item calls a friendly version of the Plum boss to fight for you for 10 seconds

    It will jump to the nearest enemy, slam on the ground and fire tears around it, then propel itself around the room, dealing contact damage to any enemies it touches before disappearing

    UNLOCK: Unlock this item by allowing Baby Plum to escape instead of killing her

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Item Room

    *, extremely cute omg :plumsmug:

  • Star of Bethlehem

    ItemID: 651

    "Follow the light"

    Quality: 2

    Spawns a star with a white aura around it, that floats very slowly through each room, making its way towards the boss

    While standing inside the aura, you gain a big Tears Up and Damage Up

    The star continues to make its way through the floor, even if you aren't in the same room as it

    Counts as 1 or 3 astrology related items for unlocking Planetariums

    UNLOCK: Unlock this item by defeating Delirium as Bethany

      Type: Passive, Familiar

      Item Pool: Angel Room

    *,

  • Cube Baby

    ItemID: 652

    "Kick it!"

    Quality: 1

    Gives you a baby in an ice cube, which can be kicked around the room by walking into it

    Enemies take damage from Cube Baby depending on how fast it was travelling when it hit them. Having a higher movement speed allows you to kick it harder

    Enemies hit by the cube while moving have a high chance to become frozen. Frozen enemies never unfreeze and are considered dead by the game. Kicking a frozen enemy will push it into the wall, where it shatters and fires ice shards everywhere (these can then freeze other enemies)

    Enemies touching the cube while it's not moving or moving slowly will become slowed for a few seconds, and take a small amount of damage

    Cube Baby and enemies frozen will block enemy shots

      Type: Passive, Familiar

      Item Pool: Item Room

    *,

  • Vade Retro

    ItemID: 653

    "Begone!"

    Quality: 3

    Enemies that die now spawn a red ghost, that floats in place of where the enemy died

    Activating the item causes all red ghosts in the room to explode, dealing damage to any enemies near them

    The explosion doesn't deal damage to Isaac

    The red ghosts can be moved around slightly by firing tears through them

    UNLOCK: Unlock this item by defeating Greedier mode as Bethany

      Type: Active

      Recharge time: Instant

      Item Pool: Angel Room

    *,

  • False PHD

    ItemID: 654

    "Worse pills + evil up"

    Quality: 2

    +1 Black Heart

    Identified all pills on pickup, and converts them to their worse counterparts (e.g. Stat Up becomes Stat Down)

    Any 'Stat down' pills you take give you a permanent +0.6 Damage Up

    Most other negative pills spawn a black heart when used, including R U A Wizard?, Amnesia, Bad Trip, ???, Paralysis, Retro Vision, I'm Excited

      Type: Passive

      Item Pool: Devil Room

    *, p.h.d ph.d p.hd paper blood

  • Spin to Win

    ItemID: 655

    "Let it rip!"

    Quality: 1

    While held, gives you an orbital that blocks enemy shots and deals contact damage equal to 3.5 per tick

    When activated, the orbital will spin way faster and deal 11.3 damage per tick. Isaac will also gain +0.5 Speed Up while active

      Type: Active & Passive, Familiar

      Item Pool: Item Room

    *,

  • Vasculitis

    ItemID: 657

    "Clogged enemies"

    Quality: 2

    On death enemies now fire tears in random directions, which can damage other enemies

    Isaac doesn't take damage from the tears from this item

    Amount of tears generated appears to scale with enemy health

      Type: Passive

      Item Pool: Item Room

    *,

  • Giant Cell

    ItemID: 658

    "Micro friends"

    Quality: 1

    Every time you take damage, a tiny Isaac familiar will spawn, which follows you and shoots tears at nearby enemies that deal 1.3 Damage

    The mini-Isaacs stay with you between floors, but can die if they take too much damage

    Maximum number of mini-Isaacs is 16 at one time

    Mini-Isaac's keep some of the abilities and appearance that Isaac has - e.g. the ability to fly

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *,

  • Tropicamide

    ItemID: 659

    "Tear size + range up"

    Quality: 1

    +5.25 Range Up

    Tear Size Up

      Type: Passive

      Item Pool: Boss Room

    *,

  • Card Reading

    ItemID: 660

    "A link to your future"

    Quality: 3

    At the beginning of all future floors, two portals will appear, that can take you to either the Boss room (Red portal), Item room (Yellow portal) or Secret room (Blue portal)

      Type: Passive

      Item Pool: Shop

    *,

  • Quints

    ItemID: 661

    "They lurk inside"

    Quality: 1

    Every time an enemy dies, a random familiar spawns where it was killed for the rest of the room

    The familiar cannot move, but continues to do its usual abilities

    Some of the possible familiars include: Brother Bobby, Sister Maggy, Little Steven, Demon Baby, Multidimensional Baby, Freezing Baby, Rotten Baby, Harlequin Baby and many more

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *,

  • Tooth and Nail

    ItemID: 663

    "You feel prickly"

    Quality: 2

    Every 5 seconds you become spiky for a brief moment, and deal contact damage to enemies

    While in this state you have invincibility to damage

      Type: Passive

      Item Pool: Item Room

    *,

  • Binge Eater

    ItemID: 664

    "All you can eat"

    Quality: 3

    Causes all pedestal items to show up as rotating items, that swap between the spawned item and a HP up item every second. This allows you to choose between the item that originally spawned and a HP upgrade every time

    When you pick up an item that increases your maximum HP, you gain a temporary damage boost that slowly goes down over time. Starts at +3.6 damage and goes to 0 after 30 seconds

    This effect applies to all items, including those in the shop and devil room

      Type: Passive

      Item Pool: Secret Room

    *,

  • Guppy's Eye

    ItemID: 665

    "An eye for secrets"

    Quality: 2

    Shows you to see the contents of chests, and items that will drop from fires and poops before you destroy them

    Counts as 1 of 3 cat items needed towards the Guppy transformation

    UNLOCK: Unlock this item by defeating Mother in the Corpse II as Cain

      Type: Passive

      Item Pool: Devil Room, Red Chest

    *, guppys eye, guppy eye

  • Strawman

    ItemID: 667

    "A helping hand"

    Quality: 2

    Spawns a Keeper familiar, that shoots triple tears and follows your exact movements as you walk

    The keeper has 3 health coins and can die if it takes enough damage. He can pick up coins to restore health

    Similar to other familiars of this kind, you can hold the drop key to cause him to stand still

    If he dies, his corpse turns into a few blue spiders. He won't respawn even if you move to a new floor

    UNLOCK: Unlock this item by defeating The Beast as Tainted Keeper

      Type: Passive, Familiar

      Item Pool: Secret Room

    *,

  • Dad's Note

    ItemID: 668

    "..."

    Quality: 0

    Only found in the Mausoleum/Gehenna II boss room

    The item itself has no effect, but triggers to backwards path towards the Home floor

    Once you've beaten Mother once, a door will appear at the starting room in Depths II, which leads to the Mausoleum/Gehenna floors. The door can only be opened if you have The Polaroid, The Negative or Faded Polaroid (the item/trinket is taken away when it opens). This means you need a way to teleport out of the Mom's Foot boss fight. If you didn't find one before this point, there will be a tinted Skull somewhere on Depths II, which contains a Fool card when blown up.

      Type: Passive

      Item Pool: None (see above)

    *, dads note, dad note

  • Sausage

    ItemID: 669

    "All stats up"

    Quality: 3

    +1 HP

    +0.2 Speed Up

    +0.5 Tears Up

    +0.5 Damage Up

    +1.5 Range Up

    +0.16 Shot Speed Up

    +1 Luck Up

      Type: Passive

      Item Pool: Secret Room

    *, sosig

  • Options?

    ItemID: 670

    "There might be options"

    Quality: 2

    Clearing a room will spawn an extra reward, however only one can be picked up - the other one will disappear

    UNLOCK: Unlock this item by defeating the The Beast as Isaac

      Type: Passive

      Item Pool: Shop

    *,

  • Candy Heart

    ItemID: 671

    "Power of love"

    Quality: 2

    Every red heart you pick up gives a small but permanent stat increase

    Randomly picks between +0.05 Tears Up, +0.15 or +0.3 Range Up, +0.02 or +0.04 Speed Up, +0.1 Luck Up, +0.04 Shot Speed Up

    UNLOCK: Unlock this item by defeating The Beast as Magdalene

      Type: Passive

      Item Pool: Item Room

    *,

  • A Pound of Flesh

    ItemID: 672

    "Blood money"

    Quality: 1

    This item causes Devil deals to cost money instead of hearts, and shop items to cost hearts instead of money

    Shop items cost heart containers, and pickups have spikes around them

    The Devil deal conversion rate is 1 heart container to 15 coins

    Devil deal items can be on discount similar to the shop, making it 1 heart container = 7 coins instead

    UNLOCK: Unlock this item by defeating The Beast as Cain

      Type: Passive

      Item Pool: Devil Room, Demon Beggar

    *,

  • Redemption

    ItemID: 673

    "Deliver me from evil"

    Quality: 2

    Every time you enter a devil room and choose not to take an item, you get +1 Damage Up upon entering the next floor

    The effect is shown via a cross above Isaac's head. Taking a Devil deal breaks the cross and prevents the damage up next floor

    Taking free pickups such as Black hearts in the Devil room also count

    UNLOCK: Unlock this item by defeating The Beast as Judas

      Type: Passive

      Item Pool: None

    *,

  • Spirit Shackles

    ItemID: 674

    "Unfinished business"

    Quality: 3

    When you die, you turn into a ghost with 1/2 a red heart, flying and spectral tears, that is chained to your body for 10 seconds. This allows you to stay alive as long as you don't get hit during this 10 second period.

    The effect cannot activate again until you pick up a soul heart (won't be added to your health total when this happens).

    UNLOCK: Unlock this item by defeating The Beast as The Forgotten

      Type: Passive

      Item Pool: Secret Room

    *,

  • Cracked Orb

    ItemID: 675

    "Shards of knowledge"

    Quality: 1

    Taking damage reveals a random room on the minimap, and automatically opens certain doors in the current room. Possible doors include any needing a key to open (Item Room, Shop, Alt Path doors), secret rooms and crawl spaces

    Cracked Orb can also reveal the location of the red room that contains a pedestal item. The Red Key item is required to access it, but it shows the direction to get there

    UNLOCK: Unlock this item by defeating The Beast as Eve

      Type: Passive

      Item Pool: Item Room, Secret Room

    *,

  • Empty Heart

    ItemID: 676

    "It multiplies"

    Quality: 2

    Adds an empty heart container at the start of each floor

    UNLOCK: Unlock this item by defeating The Beast as Samson

      Type: Passive

      Item Pool: Item Room, Demon Beggar

    *,

  • Astral Projection

    ItemID: 677

    "The true out-of-body experience!"

    Quality: 2

    The first time you get hit in each room, instead of taking damage Isaac will now temporarily die and become The Lost

    During this effect, time stops for 3 seconds allowing you to escape and get a few extra shots in

    Isaac returns to his body if you either clear the room or take damage while as The Lost

    Only happens once per room - taking damage a second time removes hearts as normal

    UNLOCK: Unlock this item by defeating The Beast as Lazarus

      Type: Passive

      Item Pool: Item Room, Secret Room

    *,

  • C Section

    ItemID: 678

    "Fetus shots"

    Quality: 4

    Instead of tears, you have a baby that shoots out of Lilith and deals x3 your tear damage to enemies it hits

    The baby is attached via a cord, and returns to you while not pressing the fire button

    Holding the fire button causes the baby to shoot tears of its own. Alternatively you can spam press the fire button to whip the baby at enemies and deal more damage

    Tainted Lilith starts with this item

    UNLOCK: Unlock this item by defeating The Beast as Lilith

      Type: Passive

      Item Pool: None (Tainted Lilith only)

    *,

  • Lil Abaddon

    ItemID: 679

    "Abyssal friend"

    Quality: 3

    Gives you a familiar that can be charged up to release a black ring, that damages any enemies that touch it with rapid hits (similar to Maw of the Void / Athame effects)

    The effect does a decent amount of damage, but doesn't scale with your damage upgrades

    UNLOCK: Unlock this item by defeating The Beast as Azazel

      Type: Passive, Familiar

      Item Pool: Devil Room

    *,

  • Montezuma's Revenge

    ItemID: 680

    "Oh no..."

    Quality: 3

    While firing tears, you now charges up a poop attack for 3 seconds that when released, fires from Isaac's behind

    The poop attack deals your current tear damage to any enemies caught in the blast

    Counts as 1 of 3 poop items needed towards the Oh Crap transformation

    UNLOCK: Unlock this item by defeating The Beast as ???

      Type: Passive

      Item Pool: Item Room

    *, Montezumas revenge

  • Lil Portal

    ItemID: 681

    "It hungers"

    Quality: 1

    Gives Isaac a little portal familiar, that moves across the screen as you're firing

    The portal will suck up any consumables and trinkets it travels over, causing it to become larger and deal more contact damage

    When the portal sucks up 4 pickups, it turns into a portal that can be used to teleport to unexplored rooms around the floor. It can take take you to rooms that require bombs/keys, e.g. the Secret Room or the Shop

    Every time the portal sucks up an item, it spawns a blue attack fly for you

    Once every room has been explored, the portal does nothing

    Cannot take you to rooms that aren't a part of the floor structure e.g. Devil Rooms / I AM ERROR rooms

    UNLOCK: Unlock this item by defeating Mother as Apollyon

      Type: Passive, Familiar

      Item Pool: Item Room

    *,

  • Worm Friend

    ItemID: 682

    "Clingy buddy"

    Quality: 2

    You gain a familiar that lives under the floor. Every so often it will come up and attempt to grab onto a random enemy in the room, holding them in place and dealing damage

    The Worm Friend deals 4 damage for 8 ticks total

    If the enemy moves quickly enough it can miss its attack

    UNLOCK: Unlock this item by defeating The Beast as Apollyon

      Type: Passive, Familiar

      Item Pool: Item Room

    *,

  • Bone Spurs

    ItemID: 683

    "Break your enemies"

    Quality: 2

    Enemies that die will leave behind 1-2 floating bone shards where they die, until you leave the room

    Other enemies that touch the bone shards will take 3.5 damage, with a chance to either bounce off them or cause it to break and disappear

    UNLOCK: Unlock this item by defeating Mother as The Forgotten

      Type: Passive

      Item Pool: Item Room

    *,

  • Hungry Soul

    ItemID: 684

    "Out for blood"

    Quality: 3

    Each time an enemy dies, a friendly red soul appears. It will hunt down other enemies, dealing contact damage which scales with your tear damage

    After 5 seconds the red soul explodes (Isaac doesn't take damage from this effect)

    UNLOCK: Unlock this item by defeating The Beast as The Lost

      Type: Passive

      Item Pool: Devil Room

    *, this item is irrelevant 99.94% of you wont kill the beast as the lost me included :(

  • Jar of Wisps

    ItemID: 685

    "Your faith grows"

    Quality: 2

    When used, gives you number of blue flame orbitals based on the number shown over this item

    It starts at 1, and increments each activation, giving you more familiars each time you use it

    The flames fire tears at the same time Isaac does, that deal a flat 3 damage

    If a flame touches an enemy, it deals contact damage equal to double your current tear damage and then disappears

    You can have a maximum of 24 flame orbitals at once

    Each flame has a chance to spawn as one of many variants, such as green flames that poison enemies, or a crucifix flame that spawns a random horseman familiar + Locusts when it is extinguished

    UNLOCK: Unlock this item by defeating The Beast as Bethany

      Type: Active

      Recharge time: 12 rooms

      Item Pool: Angel Room

    *,

  • Soul Locket

    ItemID: 686

    "Power of faith"

    Quality: 2

    +1 Soul Heart

    Soul hearts give you small permanent stat increases when picked up

    Possible stats include +0.3 Range Up, +0.2 Luck Up, +0.2 Damage Up, +0.1 Tears Up, +0.04 Speed Up

    UNLOCK: Unlock this item by defeating Greed Mode as Bethany

      Type: Passive

      Item Pool: Angel Room

    *,

  • Friend Finder

    ItemID: 687

    "Best friends forever!"

    Quality: 3

    Spawns a random charmed enemy which fights by your side and copies your exact movements, similar to how Jacob & Esau work

    The familiars fire tears at the same time as Isaac, and have a visible health bar showing how much damage they can take before dying

    UNLOCK: Unlock this item by defeating The Beast as Jacob & Esau

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Item Room, Crane Game

    *,

  • Inner Child

    ItemID: 688

    "Let him free"

    Quality: 3

    Gives you an extra life

    You respawn as a tiny version of Isaac, with a greatly reduced hitbox

    UNLOCK: Unlock this item by defeating Greed Mode as Jacob & Esau

      Type: Passive

      Item Pool: Secret Room

    *,

  • Glitched Crown

    ItemID: 689

    "?????"

    Quality: 4

    Item pedestals now cycle between 5 random items

    UNLOCK: Unlock this item by defeating The Beast as Tainted Isaac

      Type: Passive

      Item Pool: Secret Room

    *,

  • Belly Jelly

    ItemID: 690

    "Bounce away!"

    Quality: 2

    Enemies that touch Isaac will now bounce off him and fly off in the opposite direction

    Bounced enemies will take 10 damage if they slam into the wall

    This item also gives a random chance for enemy shots to bounce off you without taking damage

    UNLOCK: Unlock this item by defeating The Beast as Tainted Magdalene

      Type: Passive

      Item Pool: Item Room

    *,

  • Sacred Orb

    ItemID: 691

    "Destined for greatness"

    Quality: 4

    Increases the quality of generated items

    Rerolls items with a quality of 0 or 1

    33% chance to reroll items with a quality of 2

    Quality is a hidden mechanic in Repetance for all items and ranges from 0-4. Certain items consider Quality for picking what item to spawn, allowing better items to spawn under certain conditions

    UNLOCK: Unlock this item by defeating The Beast as Tainted Lost

      Type: Passive

      Item Pool: Angel Room, Secret Room

    *,

  • Sanguine Bond

    ItemID: 692

    "He awaits your offering"

    Quality: 1

    Spawns a special set of spikes in the Devil Room

    Taking damage from the spikes has a chance to spawn a reward

    6 Pennies - 35% chance

    +0.5 Damage Up - 15% chance

    2 Black Hearts - 5% chance

    Random Item - 2% chance

    Leviathan trasformation - 1% chance

    UNLOCK: Unlock this item by defeating The Beast as Tainted Judas

      Type: Passive

      Item Pool: Devil Room, Curse Room

    *,

  • The Swarm

    ItemID: 693

    "Infest"

    Quality: 2

    When picked up, this gives you 9 orbital flies

    Each time a fly blocks an enemy shot, it will turn into a blue fly and attack nearby enemies, leaving you with one less orbital

    Every room clear gives you +1 orbital fly, up to a maximum of 9

    UNLOCK: Unlock this item by defeating The Beast as Tainted Blue Baby

      Type: Passive

      Item Pool: Item Room, Key Beggar

    *,

  • Heartbreak

    ItemID: 694

    "Eternal sorrow"

    Quality: 3

    +0.75 Damage Up, and adds 3 'broken' heart containers

    The 'broken' heart containers mean the maximum health limit is reduced by 3 for the rest of the run, leaving you with a max total of 9 instead of the usual 12

    UNLOCK: Unlock this item by defeating The Beast as Tainted Eve

      Type: Passive

      Item Pool: Devil Room, Curse Room

    *,

  • Bloody Gust

    ItemID: 695

    "May your rage bring haste"

    Quality: 3

    Every time you take damage, you gain a Speed Up and a Tears Up

    The stat increases start small, and scale up each time you take damage (+0.25 Tears Up for the first hit, +0.75 Tears Up for the 6th hit)

    The effect maxes out at +3 Tears Up and +1 Speed Up after taking damage 6 times. This brings you to the maximum possible speed

    The effect lasts for the rest of the current floor

    UNLOCK: Unlock this item by defeating Mother as Samson

      Type: Passive

      Item Pool: Item Room, Devil Room

    *,

  • Salvation

    ItemID: 696

    "Divine protection"

    Quality: 2

    Isaac gains a halo of light around him. When an enemy touches the halo for couple of seconds, a beam of light will come down and deal a burst of damage to it

    The triggered beam also fires in all 4 cardinal directions, dealing damage to anything it touches

    Every time an enemy is killed with this effect, the halo grows slightly bigger

    UNLOCK: Unlock this item by defeating The Beast as Tainted Lazarus

      Type: Passive

      Item Pool: Angel Room

    *,

  • Vanishing Twin

    ItemID: 697

    "He wants revenge"

    Quality: 3

    A fetus familiar follows Isaac, and upon entering the Boss room on each floor, it will transform into a copy of the boss

    This makes bosses a lot harder, however you now get 2 boss item drops

    UNLOCK: Unlock this item by defeating Hush as Jacob & Esau

      Type: Passive, Familiar

      Item Pool: Secret Room, Curse Room

    *,

  • Twisted Pair

    ItemID: 698

    "Double trouble!"

    Quality: 4

    You gain two familiar demons, that stay by Isaac's side and fire shots in the same direction as you

    The familiars deal roughly 40% of Isaac's damage, scaling with damage upgrades you get

    They sit near and rotate around Isaac depending on which way you're firing tears. They do not block enemy shots

    UNLOCK: Unlock this item by defeating The Beast as Tainted Lilith

      Type: Passive, Familiar

      Item Pool: Devil Room

    *,

  • Azazel's Rage

    ItemID: 699

    "Ancient power"

    Quality: 3

    Isaac builds rage each time you clear a new room. This is shown by the Azazel skin spreading on Isaac's face

    After 4 rooms, Isaac's face will flash red. The next room you enter he will automatically fire a massive red brimstone laser for 4 seconds, dealing huge damage

    The rage resets back to zero, and the cycle continues every 5 rooms cleared

    UNLOCK: Unlock this item by defeating The Beast as Tainted Azazel

      Type: Passive

      Item Pool: Devil Room

    *, azazels rage, azazel rage

  • Echo Chamber

    ItemID: 700

    "I can see see the future future future"

    Quality: 2

    When using a pill or card, Echo Chamber activates one of every pill type and card type that has been previously used since obtaining Echo Chamber

    UNLOCK: Unlock this item by defeating The Beast as Tainted Apollyon

      Type: Passive

      Item Pool: Secret Room

    *,

  • Isaac's Tomb

    ItemID: 701

    "Buried memories"

    Quality: 3

    Spawns a wooden chest at the start of all future floors

    The wooden chest can contain: 3 trinkets, 1-3 soul hearts, a random item from the Wooden Chest pool

    UNLOCK: Unlock this item by defeating The Beast as Tainted Forgotten

      Type: Passive

      Item Pool: Secret Room

    *, isaacs tomb, isaac tomb

  • Vengeful Spirit

    ItemID: 702

    "Hot blooded"

    Quality: 2

    Each time you take damage, a red flame orbital will appear around Isaac for the remainder of the floor, up to a maximum of 6

    The flames deal contact damage which scales with your tear damage

    Upon reaching 6 flames, they will also start to fire tears along with Isaac, dealing a flat 3.2 damage per tear

    When entering a new floor, all the flames disappear

    UNLOCK: Unlock this item by defeating The Beast as Tainted Bethany

      Type: Passive

      Item Pool: Devil Room, Curse Room

    *,

  • Esau Jr

    ItemID: 703

    "Lost brother"

    Quality: 2

    Using this item swaps you between the character you started as, and Esau, which has 3 black hearts, +2 base damage and the ability to fly

    This character keeps its own separate health and items. Items picked up are not shared between the two characters

    If either character dies it's game over

    UNLOCK: Unlock this item by defeating The Beast as Tainted Jacob

      Type: Active

      Recharge time: 1 room

      Item Pool: Item Room, Secret Room

    *,

  • Berserk!

    ItemID: 704

    "Rip and tear"

    Quality: 3

    When activated, Isaac gets a bone sword and goes on a killing rampage, gaining +0.4 Speed, +3 Flat Damage Up

    The sword deals x4 damage if used at close range, or x2 damage if charged up and thrown

    Clearing rooms doesn't charge this item - charge is added equal to damage taken by enemies. This includes all sources of damage, including environmental damage to enemies

    The bone sword from this item is similar to Donkey Jawbone from Antibirth

    Tainted Samson starts with a passive version of this item

    UNLOCK: Unlock this item by defeating Delirium as Tainted Samson

      Type: Active

      Recharge time: Enemy damage taken = charge

      Item Pool: Devil Room

    *, berzerk, bamson

  • Dark Arts

    ItemID: 705

    "One with the shadows"

    Quality: 2

    When used, Isaac turns into a ghost for 1 second and his speed goes up to maximum (2.0). During this time he can walk over enemies to mark them for death. When the effect wears off, Isaac quickly runs between each marked enemy, dealing high damage to each one rapidly (roughly x2.5 your tear damage)

    The damage caused by this effect scales up with every target it hits in a row

    Tainted Judas starts with this item

    UNLOCK: Unlock this item by defeating Delirium as Tainted Judas

      Type: Active

      Recharge time: 7 seconds

      Item Pool: Devil Room

    *, budas, jubas

  • Abyss

    ItemID: 706

    "Come forth from the depths"

    Quality: 4

    When used, Abyss consumes all pedestal items in the current room and converts them into Red attack flies

    Red attack flies will charge across the room in the same direction Isaac is shooting, dealing contact damage to enemies equal to Isaac's tear damage

    The flies don't block enemy shots, but this also means they never die and stay with Isaac forever

    Tainted Apollyon starts with this item

    UNLOCK: Unlock this item by defeating Delirium as Tainted Apollyon

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Devil Room

    *,

  • Supper

    ItemID: 707

    "HP up"

    Quality: 1

    +1 HP Up

      Type: Passive

      Item Pool: Boss Room

    *,

  • Stapler

    ItemID: 708

    "DMG up"

    Quality: 3

    +1.0 Damage Up

    Staples one of Isaac's eyes shut, meaning he only shoots tears from one eye. This means some effects such as R U A WIZARD pills only fire tears in one direction

      Type: Passive

      Item Pool: Boss Room

    *,

  • Suplex!

    ItemID: 709

    "Angel breaker"

    Quality: 3

    When used, you charge forwards for a second. If you touch an enemy in that time, Isaac will pick it up and slam it on the ground, killing it and sending a shockwave around the impact

    In the brief period while holding the enemy you can move a target to decide where it lands

    Actually does work on bosses! However after the attack you end up near the boss, which puts you in danger of taking damage too

    UNLOCK: Unlock this item by defeating Delirium as Jacob & Esau

      Type: Active

      Recharge time: 8 seconds

      Item Pool: Item Room, Crane Game

    *,

  • Bag of Crafting

    ItemID: 710

    "Make your destiny"

    Quality: 3

    Can be used to store up to 8 consumables in, such as hearts, coins, keys, bombs, cards etc

    When the bag has 8 items you can hold down the activate button for 2 seconds to craft yourself a brand new item

    Each combination of pickups you hold in the bag will create a specific item. Check out the Mechanics > Bag of Crafting page to see combinations (Coming soon!)

    Has other uses - Will deal 3 damage to enemies it hits, and can be used to quickly push bombs and objects across rooms

    Tainted Cain starts with this item

    UNLOCK: Unlock this item by defeating Delirium as Tainted Cain

      Type: Active

      Recharge time: Instant

      Item Pool: None

    *, Bain

  • Flip

    ItemID: 711

    "Life and death"

    Quality: 3

    Tainted Lazarus starts with this item - it doesn't appear in any item pools

    When used, this allows you to switch characters between Lazarus and Dead Lazarus. Each character keeps its own items and health

    Tainted Lazarus automatically swaps between these characters after clearing each room, but this item allows you to choose to manually swap if needed

    UNLOCK: This item comes along with Tainted Lazarus. The achievement 'Flip' is unlocked by defeating Delirium as Tainted Lazarus

      Type: Active

      Recharge time: 6 rooms

      Item Pool: None

    *, Bazarus

  • Lemegeton

    ItemID: 712

    "Item summoner"

    Quality: 3

    When used, gives you an orbital flame which represents another passive item in the game. While you have this flame you also have that item's effect

    The flame deals double your tear damage to any enemies that touch it, but if it takes too much damage the flame will disappear and you lose the item's effect

    Tainted Bethany starts with this item

    UNLOCK: Unlock this item by defeating Delirium as Tainted Bethany

      Type: Active

      Recharge time: 6 rooms

      Item Pool: Devil Room, Library

    *,

  • Sumptorium

    ItemID: 713

    "Return"

    Quality: 3

    Tainted Eve will passively spawn blood clot familiars while shooting tears, which consume 1/2 a red heart each time one is spawned. This can only take you down to a minimum of 0.5 total red hearts

    Sumptorium allows you to suck up all the blood clot familiars and convert them all back into red health

    Tainted Eve starts with this item

    UNLOCK: This item comes along with Tainted Eve. The achievement 'Sumptorium' is unlocked by defeating Delirium as Tainted Eve

      Type: Active

      Recharge time: 3 seconds

      Item Pool: None (Tainted Eve only)

    *,

  • Recall

    ItemID: 714

    "Come back"

    Quality: 0

    Tainted Forgotten's Birthright effect. Cannot be obtained and has no use for any other character

    Birthright is a Shop item that has unique effects depending on what character you're playing as

    When used, this will send the Forgotten's skeleton head back to its owner's hands

      Type: Active

      Recharge time: 3 seconds

      Item Pool: None

    *,

  • Hold

    ItemID: 715

    "Saved for later"

    Quality: 0

    This is the item Tainted Blue Baby (???) uses as his main mechanic

    Killing or damaging enemies spawns various poops, which add to his collection. Pressing the bomb button will put the next poop into the 'Hold' jar. Pressing it again allows you to throw it at enemies. Each poop has random effects like Butt Bombs, Fire Poops etc

    Tainted Blue Baby starts with this item, and is the only one who can use it

      Type: Active

      Recharge time: Instant

      Item Pool: None

    *,

  • Keeper's Sack

    ItemID: 716

    "Spending power"

    Quality: 3

    Spawns 3 random coins and a key when picked up

    Buying items from the shop gives you random stat upgrades. The more you spend the higher the stat increase

    Possible stats include Speed, Damage and Range

    15c items give all 3 stats: +1 Damage Up, +0.03 or +0.06 Speed Up, +0.25 or +0.5 Range Up

    5c items give 1 or 2 stats: +0.5 Damage Up **OR** +0.25 Range and +0.03 Speed Up

    UNLOCK: Unlock this item by defeating Mother as The Keeper

      Type: Passive

      Item Pool: Shop, Secret Room

    *, keepers sack, keeper sack

  • Keeper's Kin

    ItemID: 717

    "Under a rock"

    Quality: 2

    Rocks and pots spawn 2 blue spiders when they are broken

    UNLOCK: Unlock this item by defeating Delirium as Tainted Keeper

      Type: Passive

      Item Pool: Item Room, Secret Room

    *, keepers kin, keeper kin

  • Keeper's Box

    ItemID: 719

    "Portable shop"

    Quality: 3

    When used, spawns a random shop item or consumable, however you have to pay the relevant cost to pick it up

    Can include anything that would appear in the shop

    UNLOCK: Unlock this item by defeating The Beast as Keeper

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Shop, Secret Room, Wooden Chest

    *, keepers box, keeper box

  • Everything Jar

    ItemID: 720

    "Anything is possible"

    Quality: 2

    With every bar of charge this item has, a different item is shown inside the Jar. Items start as poops/coins at low charge, moving up to cards, pills and golden

    At the full 12 charges, a completely random effect will happen. It can be anything including spawning a bunch of consumables, spawning a glitched pedestal item, creating a bunch of light beams, spawning troll bombs or nothing at all

    UNLOCK: Unlock this item by defeating The Beast as Eden

      Type: Active

      Recharge time: 12 rooms

      Item Pool: Item Room, Crane Game

    *,

  • TMTRAINER

    ItemID: 721

    "Isaac and his mother lived alone in a small house on a hill"

    Quality: 2

    When picked up, all future items become 'glitched', causing them to become random combinations of 2-3 effects based on other items

    Glitched items can be passive or active and are completely randomly generated with infinite possibilities (similar to other 'Randomizer' games)

    Random effects combine effects that exist on other items, and assign them to a random event (e.g. on enemy death, on room clear, on damage taken etc.)

    UNLOCK: Unlock this item by defeating The Beast as Tainted Eden

      Type: Passive

      Item Pool: Secret Room

    *,

  • Anima Sola

    ItemID: 722

    "Repent"

    Quality: 2

    When used, it puts the closes enemy in chains for 5 seconds, preventing it from moving

    Tainted Jacob starts with this item

    UNLOCK: Unlock this item by defeating Delirium as Tainted Jacob

      Type: Active

      Recharge time: 15 seconds

      Item Pool: Item Room

    *, Bacob

  • Spindown Dice

    ItemID: 723

    "-1"

    Quality: 4

    Rerolls all pedestal items, lowering all their internal item IDs by 1

    For example: Brimstone's ID = 118, so it would be rerolled into Dead Bird (ID = 117)

    Sad Onion (ID = 1) will reroll into nothing

    There are some gaps in item IDs which are skipped if no item exists, or will reroll into unexpected items if hidden items are present at that ID. For example rerolling Plan C (ID = 475) changes it into the Broken Glass Cannon, which is a hidden item with ID = 474

    Items that are yet to be unlocked will also be skipped over, preventing you from getting items you don't have access to yet

    UNLOCK: Unlock this item by defeating Delirium as Tainted Isaac

      Type: Active

      Recharge time: 6 rooms

      Item Pool: Item Room, Secret Room, Crane Game

    *,

  • Hypercoagulation

    ItemID: 724

    "Thick blooded"

    Quality: 3

    Upon taking damage you have a chance to drop the heart that you just lost. It gives you 2 seconds to pick it up again to re-heal, before it disappears

    UNLOCK: Unlock this item by defeating Delirium as Tainted Magdalene

      Type: Passive

      Item Pool: Item Room

    *,

  • IBS

    ItemID: 725

    "Your stomach rumbles"

    Quality: 2

    Causes Isaac to throw a random type of poop, at random intervals

    An addition chance for Explosive Diarrhea to happen, which spawns 5 troll bombs where Isaac is standing

    UNLOCK: Unlock this item by defeating Delirium as Tainted Blue Baby

      Type: Passive

      Item Pool: Item Room

    *,

  • Hemoptysis

    ItemID: 726

    "Double tap sneeze"

    Quality: 3

    Allows you to quickly double tap a shoot button to sneeze on nearby enemies, dealing x1.5 your tear damage

    UNLOCK: Unlock this item by defeating Delirium as Tainted Azazel

      Type: Passive

      Item Pool: Item Room

    *,

  • Ghost Bombs

    ItemID: 727

    "Spooky blast +5 bombs"

    Quality: 2

    +5 Bombs

    Bombs spawn a friendly white soul, which will hunt down other enemies, dealing contact damage which scales with your tear damage

    After 10 seconds the red soul explodes (Isaac doesn't take damage from this effect)

    UNLOCK: Unlock this item by defeating Delirium as Tainted Lost

      Type: Passive

      Item Pool: Item Room, Bomb Beggar

    *,

  • Gello

    ItemID: 728

    "Demonic gestation"

    Quality: 2

    When used, allows you to throw a familiar, which deals x3 your tear damage to any enemies it touches

    The familiar is attached via an Umbilical Cord, but will move and shoot in the same direction Isaac is shooting

    Can be used multiple times per room to spawn more familiars, however they only last for the current room

    UNLOCK: Unlock this item by defeating Delirium as Tainted Lilith

      Type: Active

      Recharge time: 2 rooms

      Item Pool: Item Room, Devil Room

    *,

  • Decap Attack

    ItemID: 729

    "Chuck away!"

    Quality: 2

    When used, this item allows you to throw your head where it will sit as a stationary sentry firing bullets until you walk over and pick it up again

    Throwing Isaac's head deals 24 damage to anything it hits

    Your hitbox remains with the body. Enemies touching the head don't hurt Isaac

    UNLOCK: Unlock this item by defeating Delirium as Tainted Forgotten

      Type: Active

      Recharge time: 4 seconds

      Item Pool: Item Room,

    *,

  • Repentance Trinkets (61)

  • Jawbreaker

    TrinketID: 129

    "Don't chew on it"

    Tears have a chance to become a tooth, dealing more than triple damage

    *,

  • Chewed Pen

    TrinketID: 130

    "It's leaking"

    Tears have a chance to slow enemies

    *,

  • Blessed Penny

    TrinketID: 131

    "Wealth of purity"

    Chance to spawn half a soul heart when picking up a coin

    The chance scales up based on the coin's worth: Penny = 16.66%, Double Penny = 30.5%, Nickel = 59.7%, Dime = 83.3%

    UNLOCK: Unlock this trinket by defeating ??? as Bethany

    *,

  • Broken Syringe

    TrinketID: 132

    "Mystery medicine"

    Gives you a random syringe effect every room

    The effect can be The Virus, Roid Rage, Speed Ball, Experimental Treatment, Synthoil, Euthanasia or Growth Hormones

    *,

  • Short Fuse

    TrinketID: 133

    "Short fuse"

    Placed bombs explode almost instantly

    This was called Exploded Firecracker in Antibirth

    *,

  • Gigante Bean

    TrinketID: 134

    "Mega farts"

    Farts produced by Isaac or familiars will be twice as large

    *,

  • A Lighter

    TrinketID: 135

    "Watch the world burn"

    Chance for enemies to burn when entering a room

    The chance for this effect to activate is effected by your Luck stat

    *,

  • Broken Padlock

    TrinketID: 136

    "Bombs are key"

    Explosions can open locked doors

    This includes key blocks and golden chests

    *,

  • Myosotis

    TrinketID: 137

    "Forget me not..."

    Pickups left on current floor will appear in the starting room of the next floor, up to a maximum of 4 pickups

    *,

  • 'M

    TrinketID: 138

    "t's broken9Reroll your dest "

    Active items will be rerolled upon using them

    Breath of Life is not rerolled by this trinket

    UNLOCK: Unlock this trinket by defeating Mother as Eden

    *,

  • Teardrop Charm

    TrinketID: 139

    "It feels lucky"

    Random luck-based tear effects have an extra chance of occurring

    The additional chance is effectively +3 Luck Up

    *,

  • Apple of Sodom

    TrinketID: 140

    "It feels empty"

    Picking up red hearts now has a high chance to spawn 1-4 blue attack spiders, instead of giving you health back

    This effect also works while fully healed, giving a guaranteed chance of getting spiders

    While missing any red health the chance for spiders is less

    Works for characters that don't use red health, which always gives you spiders

    *,

  • Forgotten Lullaby

    TrinketID: 141

    "Sing for your friends"

    Gives your familiars improved rate of fire while held

    In Antibirth this trinket was called Song of the Siren

    UNLOCK: Unlock this trinket by bombing the skull left by The Siren boss after her death

    *,

  • Beth's Faith

    TrinketID: 142

    "My faith protects me"

    While held at the start of each floor, this trinket spawns four wisp familiar orbitals around Isaac

    These wisps are the same as the ones created by the Book of Virtues item

    UNLOCK: Unlock this trinket by beating the Boss Rush as Bethany

    *, beths faith

  • Old Capacitor

    TrinketID: 143

    "Voltage starving"

    Your active item no longer gains charges, but battery drops become much more common

    UNLOCK: Unlock this trinket by blowing up 10 Battery Beggars

    *,

  • Brain Worm

    TrinketID: 144

    "Ding!"

    Tears that miss enemies will redirect themselves and travel 90 degrees towards enemies

    Tears must be roughly 2 tiles or closer to activate this effect

    *,

  • Perfection

    TrinketID: 145

    "Luck way up. Don't lose it!"

    +10 Luck while held, but the trinket is destroyed when damage is taken

    Blood donation machines, Curse Rooms and Sacrifice Rooms wont destroy it

    Taking a hit and activating Holy Mantle won't destroy it

    Can be dropped in order to avoid breaking it

    This trinket is automatically given to you after clearing 3 bosses without taking damage

    *,

  • Devil's Crown

    TrinketID: 146

    "His special customer"

    Treasure Rooms are replaced with Red Treasure Rooms, which contain a deal with the devil in place of a regular item pedestal

    If an item room as not yet been entered, it can be transformed to either a regular or Red Treasure Room by picking up or dropping this trinket before entering

    UNLOCK: Unlock this trinket by defeating Mother as Azazel

    *, devils crown

  • Charged Penny

    TrinketID: 147

    "Wealth of power"

    Every time you pick up a coin, you have a small chance to gain 1 bar of charge on your active item

    In Antibirth this trinket was called Electric Penny

    UNLOCK: Unlock this trinket by donating to a battery beggar until he rewards 4.5 Volt

    *,

  • Friendship Necklace

    TrinketID: 148

    "Gather round"

    While held, your familiars will now orbit around Isaac instead of following behind him

    *,

  • Panic Button

    TrinketID: 149

    "Push in case of emergency"

    If your active item is fully charged, when you take damage it will automatically activate

    It doesn't activate for free - the charges are used up as normal if this effect activates

    *,

  • Blue Key

    TrinketID: 150

    "Look between the rooms"

    Doors can be opened without using up a key

    However, when entering the door you are taken to a blue womb room with enemies to defeat. This room will always drop a reward at the end, then allow you to exit back to the real floor

    UNLOCK: Unlock this trinket by defeating The Beast as Tainted Cain

    *,

  • Flat File

    TrinketID: 151

    "No more spikes"

    While held this trinket causes spikes to retract into the floor

    Works for curse rooms - you no longer take damage entering or leaving

    *,

  • Telescope Lens

    TrinketID: 152

    "Seek the stars"

    +9% chance for a Planetarium to spawn

    Allows Planetariums to spawn in the Womb/Utero floors

    Planetarium have a base 1% chance to appear, which increases by +20% whenever you skip an Item Room (Must not enter to count as skipped)

    After entering a Planetariumm the chance goes back to 1%. Holding this trinket increase that chance by +15%

    UNLOCK: Unlock this trinket by collecting three of the following in the same run: Magic 8 Ball, Tiny Planet, Crystal Ball, Star of Bethlehem or any of the Astrology-related items (e.g. Aries, Cancer, Capricorn, Leo etc.). The item called Zodiac does not count.

    *,

  • Mom's Lock

    TrinketID: 153

    "A piece of her love"

    Has a high chance to give you the effect of a random Mom item every room

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Isaac

    *, moms lock

  • Dice Bag

    TrinketID: 154

    "Bonus roll"

    Every time you enter a brand new room, you have a chance to get a random one-time use Dice (e.g. D6, D6, D20 etc.)

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Isaac

    *,

  • Holy Crown

    TrinketID: 155

    "Walk the path of the saint"

    Causes Item rooms to appear in the Cathedral

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Magdalene

    *,

  • Mother's Kiss

    TrinketID: 156

    "HP up"

    While held you get +1 HP Up

    The first time you pick this trinket up, the heart container will be filled. This effect can't be abused - next time it will be empty if dropped

    *, mothers kiss

  • Torn Card

    TrinketID: 157

    "Death awaits"

    Every 15 shots you will shoot an Ipecac + My Reflection shot

    The tear will fly in the air for about 3 seconds and follows Isaac until it falls and explodes. You need to move out of the way or it will hurt Isaac, but can be used to open anything requiring a bomb e.g. Secret Rooms

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Lazarus

    *,

  • Torn Pocket

    TrinketID: 158

    "A hole in your pocket"

    Every time you take damage, you drop up to 2 different types of consumables on the ground

    Dropped consumables can be any variant of its kind - e.g. a bomb can become a troll bomb, or a dropped coin can become a dime

    Does nothing if you have no consumables

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Lazarus

    *,

  • Gilded Key

    TrinketID: 159

    "Less is more"

    All new chests become locked Golden chests

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Cain

    *,

  • Lucky Sack

    TrinketID: 160

    "Free goodies!"

    Spawns a sack at the start of each new floor

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Cain

    *,

  • Wicked Crown

    TrinketID: 161

    "Walk the path of the wicked"

    Causes Item rooms to appear in Sheol

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Azazel

    *,

  • Azazel's Stump

    TrinketID: 162

    "Unleash your inner demon"

    When entering a new room, gives a small chance to gain Azazel's short-range Brimstone laser for the current room and the ability to fly

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Azazel

    *, azazels stump

  • Dingle Berry

    TrinketID: 163

    "Oops!"

    Spawns 2 friendly Dips upon clearing a room

    Dips that spawn after killing a Squirt turn friendly

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Blue Baby

    *,

  • Ring Cap

    TrinketID: 164

    "Twice the bang!"

    Drops 2 bombs at once (only 1 bomb is removed from your total)

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Blue Baby

    *,

  • Nuh Uh!

    TrinketID: 165

    "Don't want!"

    Beyond the womb floor, all pickups are replaced with a random pickup as follows:

    Bomb - 26.6% chance. Heart - 26.6% chance

    Pill - 16.6% chance. Card - 16.6% chance

    Trinket - 6.6% chance. Battery - 6.6% chance

    Essentially just removes keys from the drop table

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Eden

    *,

  • Modeling Clay

    TrinketID: 166

    "???"

    Each brand new room, this trinket has a chance to transform into a copy of a random passive item, which gives you the effect for the duration of this room

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Eden

    *,

  • Polished Bone

    TrinketID: 167

    "Friends from beyond"

    Gives a small chance to spawn a friendly Bony when clearing a room, which will throw bones at enemies until it takes enough damage to die. Max 3 Bonys at once

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Forgotten

    *,

  • Hollow Heart

    TrinketID: 168

    "A brittle blessing"

    Gives you +1 Bone Heart every time you enter a new floor

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Forgotten

    *,

  • Kid's Drawing

    TrinketID: 169

    "Looks familiar..."

    Counts as 1 of 3 cat items needed towards the Guppy transformation

    Dropping this trinket again removes the transformation if you dont have 3 other Guppy items

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Lost

    *, kids drawing

  • Crystal Key

    TrinketID: 170

    "Call to the other side"

    Each time you clear a room there is a chance a Red Room will spawn at one of the walls.

    The chance for a Red Room to unlock increases as you pick up more Crystal Keys.

    While in a regular room, the chances to spawn a Red Room are: 1 Key = 33.33% chance. 2 keys = 50% chance. 3 or more keys = 100% chance.

    While in a Red room, the chances to spawn a Red Room are: 1 Key = 12.5% chance. 2 keys = 16.6% chance. 3 keys = 25% chance. 4 keys = 50% chance. 5 keys = 100% chance.

    Passive rooms with no enemies don't have a chance to spawn Red Rooms.

    It's possible to hold more than one trinket by taking Mom's Purse, Belly Button or using the Smelter to convert them into passive items.

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Lost

    *,

  • Keeper's Bargain

    TrinketID: 171

    "Money talks"

    Has a decent chance for Devil Deals to cost money instead of Health

    The conversion rate is 1 heart container to 15 coins

    Items can be on discount similar to the shop, making it 1 heart container = 7 coins instead

    Can be dropped to disable this effect while in the room

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Keeper

    *, keepers bargain, keeper bargain

  • Cursed Penny

    TrinketID: 172

    "Wealth of misery"

    While held, you will be teleported to a random room everytime you pick up a coin

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Keeper

    *,

  • Your Soul

    TrinketID: 173

    "Give it to me"

    Allows you to pay for a devil deal with this trinket

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Judas

    *,

  • Number Magnet

    TrinketID: 174

    "6"

    +10% devil room chance while held

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Judas

    *,

  • Strange Key

    TrinketID: 175

    "What could it open?"

    Opens the door to the Blue Womb, regardless of whether you meet the 30 minute speed timer

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Eve

    *,

  • Lil Clot

    TrinketID: 176

    "Mini friend"

    A small clot friend will hug Isaac, following his exact movements (similar to how Jacob & Esau work) and shooting tears when he does

    The clot can be moved around by collision with an object/wall, allowing you to re-position it

    The clot's damage is roughly 1/3 of your tear damage

    If it takes a few hits it will die, and respawn in the next room

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Samson

    *, mini clot

  • Temporary Tattoo

    TrinketID: 177

    "You feel braver"

    Spawns a random chest after completing a regular Challenge Room

    Spawns a pedestal item after completing a boss Challenge Room

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Samson

    *,

  • Swallowed M80

    TrinketID: 178

    "Bang!"

    When taking damage you have a chance to explode and deal 185 damage to all enemies around you (Same damage as a Mr. Mega bomb)

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Samson

    *,

  • RC Remote

    TrinketID: 179

    "Controllable buddies!"

    Familiars follow Isaac's exact movements, (similar to how Jacob & Esau work) instead of following loosely like they usually do

    Holding the drop button (Ctrl on Steam version) causes them to stop moving

    Doesn't affect some familiars with specific movement patterns, e.g. Abel

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Jacob

    *,

  • Found Soul

    TrinketID: 180

    "Finally!"

    Gives you a familiar that follows Isaac's exact movements (similar to how Jacob & Esau work) and shoots spectral tears

    Similar to Jacob and Esau, positions can be altered by running it into objects, or holding the drop button (Ctrl on Steam version)

    When you place a bomb, the Found Soul will drop one too

    If it takes any damage, it will die and not respawn until the next floor

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Jacob

    *,

  • Expansion Pack

    TrinketID: 181

    "Fun extras"

    Everytime you use your active item, you have a chance to activate another random active item

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Bethany

    *,

  • Beth's Essence

    TrinketID: 182

    "Virtue's reward"

    Taking damage gives you a chance to spawn a flame orbital, similar to the ones created by Book of Virtues

    Entering an Angel Room gives you +5 flame orbitals. The angel room spawned by The Stairway item also counts

    Giving money to a beggar gives a flame orbital

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Bethany

    *, beths essence

  • The Twins

    TrinketID: 183

    "I'm seeing double..."

    Chance to spawn either Brother Bobby or Sister Maggy when entering each new room

    Only lasts for the current room

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Lilith

    *,

  • Adoption Papers

    TrinketID: 184

    "Give them a home"

    All shops only sell familiars while holding this trinket

    If you enter a shop while holding this trinket, the effect won't undo by dropping it until you move to a new floor

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Lilith

    *,

  • Cricket Leg

    TrinketID: 185

    "Infested"

    Every time an enemy dies you have a chance to gain a random Locust

    Different color Locusts correspond to the horsemen. Each of them deal double your tear damage, similar to how standard blue flies work

    War (Red) - Explodes when touching the enemy. The actual explosion deals flat 60 damage

    Pestilence (Green) - Poisons the enemy it attacks

    Famine (Brown) - Applies a slowing effect

    Death (Black) - Deals x4 damage instead of x2

    Conquest (White) - Spawns 2-5 at once

    UNLOCK: Unlock this trinket by defeating Isaac, ???, Satan and The Lamb as Tainted Apollyon

    *,

  • Apollyon's Best Friend

    TrinketID: 186

    "Attack buddy"

    Gives you a red attack fly, that will charge at enemies in the same direction you are shooting

    Deals damage equal to your current tear damage

    Stops charging once it hits an enemy and returns to Isaac's side

    UNLOCK: Unlock this trinket by defeating Mother as Tainted Apollyon

    *, apollyons best friend

  • Broken Glasses

    TrinketID: 187

    "Double vision?"

    Gives a 33% chance to spawn an extra blind pedestal item in all future item rooms. This one will be a hidden question mark

    Allows you to see what both items are on alternative path floors (Downpour/Dross, Mines/Ashpit, Gehenna/Mausoleum)

    UNLOCK: Unlock this trinket by defeating challenge #40 (Seeing Double)

    *,

  • Ice Cube

    TrinketID: 188

    "Stay frosty"

    Gives a small chance for your tears to freeze enemies in place

    Frozen enemies can be pushed into obstacles where they shatter on contact and fire ice shards around them. Any other enemies hit by these shards will become frozen too

    Frozen enemies are considered dead by the game, and won't unfreeze or move again. The room doors will open if only frozen enemies remain

    UNLOCK: Unlock this trinket by defeating challenge #41 (Pica Run)

    *,

  • Sigil of Baphomet

    TrinketID: 189

    "Revel in death"

    Every time you kill an enemy you get an invincibility shield for 2 seconds

    UNLOCK: Unlock this trinket by defeating challenge #37 (Bloody Mary)

    *,

  • Rebirth Items (341)

  • The Sad Onion

    ItemID: 1

    "Tears up"

    Quality: 3

    +0.7 Tears Up

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, green, cry, plant

  • The Inner Eye

    ItemID: 2

    "Triple shot"

    Quality: 2

    Tears now shoot three at a time (Triple Shot)

    Tears Down significantly

    REPENTANCE - The Inner Eye now causes less of a decrease in rate of fire than previously, and now has a tighter spread.

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, round, circle, white

  • Spoon Bender

    ItemID: 3

    "Homing shots"

    Quality: 3

    Gives Isaac's tears a homing effect

    REPENTANCE - Homing tears now target enemies much more reliably

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, grey, gray, bent

  • Cricket's Head

    ItemID: 4

    "DMG up"

    Quality: 4

    +0.5 Damage Up

    x1.5 times Damage Multiplier (Does not stack with the Magic Mushroom multiplier)

    Can be found in golden chests

    Cricket's Head used to be known as Max's Head in the original game and was renamed for Rebirth

      Type: Passive

      Item Pool: Item Room

    * crickets head, cricket head, item room, treasure room, item room pool, golden chest pool, gold chest pool, cat, dead, brown, pink

  • My Reflection

    ItemID: 5

    "Boomerang tears"

    Quality: 0

    Gives tears a boomerang effect

    +1.5 Range Up

    +0.6 Shot Speed Up

    +1 Tear Height

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, broken, mirror, cracked, grey, gray, silver

  • Number One

    ItemID: 6

    "Tears up"

    Quality: 2

    Gives you a very high tear rate in exchange for a big range down

    +1.5 Tears Up

    -17.62 Range Down

    +0.76 Tear Height

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, mm sweet lemonade, urine, yellow, tear, drop

  • Blood of the Martyr

    ItemID: 7

    "DMG up"

    Quality: 3

    +1.0 Damage Up

    x1.5 times Damage Multiplier if you also have Book of Belial (Does not stack with Magic Mushroom or Cricket's Head multipliers)

      Type: Passive

      Item Pool: Item Room, Angel Room

    * item room, treasure room, item room pool, crown, thorns, brown, hat

  • Brother Bobby

    ItemID: 8

    "Friends 'till the end"

    Quality: 0

    A familiar which follows Isaac and shoots normal tears which do 3.5 damage

    Counts as 1 of 3 familiar items needed towards the Conjoined transformation

    REPENTANCE - Brother Bobby now has an increased rate of fire

      Type: Passive, Familiar

      Item Pool: Item Room, Devil Room

    * item room, treasure room, item room pool, devil pool, devil room pool, devil deal, purple, blue, dead, baby

  • Skatole

    ItemID: 9

    "Fly love"

    Quality: 0

    A lot of fly enemies are no longer aggressive towards Isaac

    Attack Fly, Dart Fly, Eternal Fly, and Ring Fly are transformed into a neutral black fly

    Boom Fly, Red Boom Fly, Drowned Boom Fly move slower, but still deal contact damage

    Moter, Level 2 Fly, Full Fly, Pooter, and Super Pooter move slower and deal no contact damage

    Can only be obtained from the shell game in the arcade

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

    REPENTANCE - Skatole now prevents damage from eternal flies and Hush flies.

      Type: Passive

      Item Pool: None (Arcade shell game only)

    * arcade, skull game, black, heart, pink, love

  • Halo of Flies

    ItemID: 10

    "Projectile protection"

    Quality: 3

    Gives Isaac 2 orbital flies which block enemy shots

    Picking up this item as well as 2 other fly-type items will allow you to transform into Lord of the Flies

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive, Orbital

      Item Pool: Item Room, Key Beggar

    * item room, treasure room, item room pool, key master pool, key beggar pool, key judgement pool, two, flies, black

  • 1UP

    ItemID: 11

    "Extra life"

    Quality: 2

    Gives the player an extra life

    When revived, the green mushroom that follows Isaac will disappear and he will respawn with the same amount of red heart containers at full health

    Resurrection takes place before all other items which give you an extra life

      Type: Passive

      Item Pool: Secret Room

    * secret room pool, mario, green mushroom, extra life, spots, spotted

  • Magic Mushroom

    ItemID: 12

    "All stats up!"

    Quality: 4

    +1 HP Up

    +0.3 Damage Up

    x1.5 times Damage Multiplier (Does not stack with the multipliers from Cricket's Head / Blood of The Martyr + Book of Belial)

    +5.25 Range Up

    +0.3 Speed Up

    +0.5 Tear Height

    Increases the size of your player sprite, but doesn't increase the hitbox

    Fully restores all red heart containers

    Counts as 1 of 3 mushroom items needed towards the Fun Guy transformation

    Counts as 1 of 3 size-increasing items needed towards the Stompy transformation

      Type: Passive

      Item Pool: Item Room, Mushrooms

    * boss room pool, boss room item, item room, treasure room, item room pool, red, spots, spotted, amanita muscaria

  • The Virus

    ItemID: 13

    "Poison touch"

    Quality: 0

    Enemies touching you take 12 damage, then a poison effect is applied for 6-7 ticks, dealing damage equal to the amount of red hearts you have (up to 30.8 at 12 full red hearts)

    +0.2 Speed Up

    Has a chance to drop from the Lust miniboss fight

    Counts as 1 of 3 syringe items needed towards the Spun transformation

    REPENTANCE - +0.2 Speed Up (Used to be -0.1 Speed before Repentance). No longer drops black hearts like it used to. Damage scales with total heart containers.

      Type: Passive

      Item Pool: Item Room, Demon Beggar, Lust Miniboss

    * demon beggar pool, demon judgement pool, devil beggar pool, item room, treasure room, item room pool, syringe, needle, injection, the lost item pool, red

  • Roid Rage

    ItemID: 14

    "Speed and range up"

    Quality: 2

    +0.3 Speed Up

    +5.25 Range Up

    +0.5 Shot Height

    Counts as 1 of 3 syringe items needed towards the Spun transformation

      Type: Passive

      Item Pool: Item Room, Boss Room, Demon Beggar

    * demon beggar pool, demon judgement pool, devil beggar pool, boss room pool, boss room item, item room, treasure room, item room pool, syringe, needle, injection, green

  • <3

    ItemID: 15

    "HP up"

    Quality: 2

    +1 HP Up

    Fully restores all red heart containers

    Has a chance to drop from the Gluttony miniboss fight

      Type: Passive

      Item Pool: Item Room, Gluttony Miniboss

    * boss room pool, boss room item, item room, treasure room, item room pool, red heart, ballchinnian, ball sack, full heal, gluttony, the lost item pool

  • Raw Liver

    ItemID: 16

    "HP up"

    Quality: 2

    +2 Health Up

    Full red heart heal

      Type: Passive

      Item Pool: Secret Room

    * secret room pool, the lost item pool, brown, poop, turd

  • Skeleton Key

    ItemID: 17

    "99 keys"

    Quality: 3

    Gives Isaac 99 Keys

      Type: Passive

      Item Pool: Item Room, Secret Room

    * secret room pool, silver, grey, gray, skull

  • A Dollar

    ItemID: 18

    "$$$"

    Quality: 2

    Gives Isaac 99 coins

    Can drop from an exploding slot machine while playing it

      Type: Passive

      Item Pool: None (Arcade machine only)

    * slot machine, arcade machine, money, bill, cash, green

  • Boom!

    ItemID: 19

    "10 bombs"

    Quality: 0

    +10 Bombs

      Type: Passive

      Item Pool: Item Room

    * boss rush pool, boss rush room, item room, treasure room, item room pool, grey, gray, x10

  • Transcendence

    ItemID: 20

    "We all float down here..."

    Quality: 3

    Gives Isaac the ability to fly

    UNLOCK: Unlock this item by beating Mom's Heart 3 times

      Type: Passive

      Item Pool: Secret Room

    * secret room pool, the lost item pool, brown, noose, hang

  • The Compass

    ItemID: 21

    "The end is near"

    Quality: 2

    Shows most icons on the map (Shops, Item Rooms, Boss Rooms etc.)

    Does not show the layout of the map

    Doesn't show the location of Secret or Super Secret rooms

    Room icons will not show if a Curse of the Lost is in effect on the current floor

      Type: Passive

      Item Pool: Shop, Beggar

    * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, pink, red

  • Lunch

    ItemID: 22

    "HP up"

    Quality: 1

    +1 HP Up

    Heals one red heart container when picked up

      Type: Passive

      Item Pool: Boss Room, Challenge Room, Beggar

    * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, brown, bowl, grey, gray, poop, fly

  • Dinner

    ItemID: 23

    "HP up"

    Quality: 1

    +1 HP Up

    Heals one red heart container when picked up

      Type: Passive

      Item Pool: Boss Room, Beggar, Challenge Room

    * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, can, tin, brown

  • Dessert

    ItemID: 24

    "HP up"

    Quality: 1

    +1 HP Up

    Heals one red heart container when picked up

      Type: Passive

      Item Pool: Boss Room, Beggar, Challenge Room

    * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, brown, sack, bag, fly

  • Breakfast

    ItemID: 25

    "HP up"

    Quality: 1

    +1 HP Up

    Heals one red heart container when picked up

      Type: Passive

      Item Pool: Boss Room, Challenge Room, Beggar

    * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, carton, fly, flies, milk

  • Rotten Meat

    ItemID: 26

    "HP up"

    Quality: 1

    +1 HP Up

    Heals one red heart container when picked up

      Type: Passive

      Item Pool: Boss Room, Beggar, Challenge Room

    * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, green, bone, lump, yellow

  • Wooden Spoon

    ItemID: 27

    "Speed up"

    Quality: 1

    +0.3 Speed Up

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, brown

  • The Belt

    ItemID: 28

    "Speed up"

    Quality: 2

    +0.3 Speed Up

    REPENTANCE - Added back to the Gold Chest pool

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    * boss room pool, boss room item, brown, leather, bag, sack, golden chest pool, gold chest pool,

  • Mom's Underwear

    ItemID: 29

    "Range Up"

    Quality: 1

    +1.5 Range Up

    Gives 3-6 blue attack flies when picked up

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Passive

      Item Pool: Boss Room, Challenge Room, Gold/Stone Chest

    * dungeon room, blood challenge room, arena pool, boss room pool, boss room item, panties, pants, under wear, pink, knickers, moms underwear, mom underwear

  • Mom's Heels

    ItemID: 30

    "Range up"

    Quality: 1

    +1.5 Range Up

    Counts as 1 of 3 mom items needed towards the Mom transformation

    REPENTANCE - Touching enemies deals 12 damage to them

      Type: Passive

      Item Pool: Boss Room, Challenge Room

    * dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, high, shoe, moms heels, mom heels

  • Mom's Lipstick

    ItemID: 31

    "Range up"

    Quality: 1

    +2.25 Range Up

    Drops a random heart on the floor when picked up

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Passive

      Item Pool: Boss Room, Challenge Room

    * moms lipstick, mom lipstick, dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, grey, gray

  • Wire Coat Hanger

    ItemID: 32

    "Tears up"

    Quality: 3

    +0.7 Tears Up

    UNLOCK: Unlock this item by beating Mom's Heart 4 times

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    * boss room pool, boss room item, black

  • The Bible

    ItemID: 33

    "Temporary flight"

    Quality: 1

    Gives Isaac angel wings for the current room, allowing him to fly

    Instantly kills the Mom's Foot, Mom's Heart and It Lives boss fights

    If used during the Satan fight, The Bible will instantly kill Isaac

    Counts as 1 of 3 angel items needed towards the Seraphim transformation

    Counts as 1 of 3 book items needed towards the Bookworm transformation

    REPENTANCE - Reduced to 4 room recharge time

      Type: Active

      Recharge Time: 4 rooms

      Item Pool: Shop, Library, Angel Room

    * library pool, library room, book room pool, angel room pool, god room pool, angel room item, shop room pool, shop item pool, cross, brown

  • The Book of Belial

    ItemID: 34

    "Temporary DMG up"

    Quality: 3

    Upon use, gives +2 damage up which lasts for the current room

    x1.5 times Damage Multiplier if you also have Blood of the Martyr (Does not stack with Magic Mushroom or Cricket's Head multipliers)

    Increases your chances of getting a devil/angel room by +12.5%

    Judas starts with this item

    Counts as 1 of 3 book items needed towards the Bookworm transformation

    REPENTANCE - The effect stacks if used multiple times

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Library, Devil Room

    * library pool, library room, book room pool, devil pool, devil room pool, devil deal, starting grey, gray, pentagram

  • The Necronomicon

    ItemID: 35

    "Mass room damage"

    Quality: 1

    Deals 40 damage to everything in the room when used

    Counts as 1 of 3 book items needed towards the Bookworm transformation

    REPENTANCE - Reduced to 3 room recharge time

    UNLOCK: Unlock this item by using 4 XIII - Death cards

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Library, Secret Room, Devil Room

    * library pool, library room, book room pool, secret room pool, devil pool, devil room pool, devil deal, pink, brown, face, spots

  • The Poop

    ItemID: 36

    "Plop!"

    Quality: 0

    Drops a poop on the floor

    Blue Baby starts with this item

    Can be placed next to a pit and exploded to make a bridge

    Can be placed over a broken red poop to overwrite it, causing it to no longer regenerate

    Counts as 1 of 3 poop items needed towards the Oh Crap transformation

      Type: Active

      Recharge Time: 1 room

      Item Pool: Item Room

    * item room, treasure room, item room pool, starting, turd, brown

  • Mr. Boom

    ItemID: 37

    "Reusable bomb buddy"

    Quality: 1

    Drops a large bomb below the player which does 185 damage

    Compatible with bomb modifiers, such as Glitter Bombs, Sticky Bombs etc

    Has a chance to drop from the Wrath miniboss fight

    REPENTANCE - Damage buffed from 110 to 185

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room, Wrath Miniboss, Bomb Beggar

    * mr boom, boss rush pool, boss rush room, item room, treasure room, item room pool, bomb beggar, face, smile, grey, gray

  • Tammy's Head

    ItemID: 38

    "Reusable tear burst"

    Quality: 3

    Fires 10 tears in a circle around Isaac

    Each tear is equal to your damage stat + 25 flat damage

    The tears spawned from Tammy's Head retain tear effects of Isaac's tears, such as poison or homing

      Type: Active

      Recharge Time: 1 room

      Item Pool: Gold Chest

    * golden chest pool, gold chest pool, dead, cat, white, yellow, tammys head, tammy head

  • Mom's Bra

    ItemID: 39

    "Mass fear"

    Quality: 1

    When used, freezes all enemies in the current room for about 4 seconds

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Item Room, Challenge Room

    * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, white, brown, underwear, moms bra, mom bra

  • Kamikaze

    ItemID: 40

    "Become the bomb!"

    Quality: 0

    Causes an explosion near Isaac which takes away half a heart and does 40 damage all enemies in close proximity

    REPENTANCE - Kamikaze now has increased blast damage and radius. No longer reduces your devil/angel room chances when used

      Type: Active

      Recharge Time: Instant

      Item Pool: Item Room

    * item room, treasure room, item room pool, the lost item pool, bomb, tnt, clock, red

  • Mom's Pad

    ItemID: 41

    "Gross..."

    Quality: 0

    When used, causes all enemies in the current room to run away from Isaac in fear for 5 seconds

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Item Room, Challenge Room

    * item room, treasure room, item room pool, dungeon room, blood challenge room, arena pool, white, grey, gray moms pad, mom pad,

  • Bob's Rotten Head

    ItemID: 42

    "Reusable ranged bomb"

    Quality: 1

    A poison bomb which can be thrown and leaves a poison effect on any enemies within the blast radius. It also leaves a gas cloud at the place where it exploded

    The bomb deals 185 damage + your tear damage on hit and leaves a damage over time poison effect that does 3 times your tear damage per tick

    Synergizes with tear modifying items such as My Reflection or Tiny Planet

    Has a chance to drop from the Sloth miniboss fight

    Counts as 1 of 3 poison items needed towards the Bob transformation

    REPENTANCE - The damage of this item was significantly boosted to 185 (from 50) in Repentance, and given the poison cloud effect. Changed to 2 room recharge

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room, Sloth Miniboss

    * golden chest pool, gold chest pool, item room, treasure room, item room pool, bob sloth, grey, gray, green, mouth, bobs rotten head, bob rotten head

  • Teleport

    ItemID: 44

    "Teleport!"

    Quality: 0

    Teleports Isaac to a random location on the map

    Can't be used to teleport to the I AM ERROR room

    REPENTANCE - Teleport! now allows the player to influence the teleport direction (using the direction Isaac is moving upon activating the item)

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, blue remote, robot

  • Yum Heart

    ItemID: 45

    "Reusable regeneration"

    Quality: 1

    Heals Isaac for one whole red heart

    Maggy starts with this item

    When used as the Keeper, one coin HP is restored

    Has a chance to drop from the Super Lust miniboss fight

      Type: Active

      Recharge Time: 4 rooms

      Item Pool: Item Room, Super Lust Miniboss

    * item room, treasure room, item room pool, the lost item pool, maggy, starting, red, pink, broken

  • Lucky Foot

    ItemID: 46

    "Luck up"

    Quality: 2

    +1.0 Luck Up

    Better chance to win while gambling at the Shell Game and Fortune Telling Machine

    Higher chance to get a random drop after clearing a room

    REPENTANCE - Lucky Foot now guarantees positive pill effects

      Type: Passive

      Item Pool: Item Room, Beggar

    * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, treasure room, item room pool, starting, pink, white, yellow

  • Doctor's Remote

    ItemID: 47

    "Reusable air strike"

    Quality: 1

    A target is placed on the floor which can be controlled. After a few seconds a huge missile hits the target and deals 20x your tear damage to anything nearby

    Essentially a one-time use of the Epic Fetus item

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, grey, gray, robot

  • Cupid's Arrow

    ItemID: 48

    "Piercing shots"

    Quality: 3

    Isaac's tears now have a piercing effect which allows them to travel through enemies instead of breaking on hit

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, arrow, penetrative, penetrating shots, grey, gray, red, bolt, cupid arrow, cupids arrow

  • Shoop Da Whoop!

    ItemID: 49

    "BLLLARRRRGGG!"

    Quality: 1

    When used, fires a high damage laser in a straight line across the room in a similar way to Brimstone

    The laser deals damage equal to double your tear damage. The laser hits up to 13 times if an enemy stays inside it for the duration

    Has a chance to drop from the Envy and Super Envy miniboss fights

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room, Envy Miniboss, Super Envy Miniboss

    * item room, treasure room, item room pool, red, lips, white, eyes

  • Steven

    ItemID: 50

    "DMG up"

    Quality: 3

    +1 Damage Up

    Can only be dropped by the Steven boss

    UNLOCK: Unlock this item by beating the Basement 40 times and defeating the Steven boss

      Type: Passive

      Item Pool: Steven Boss

    *, black, white, face, eyes, mouth, golden chest pool

  • Pentagram

    ItemID: 51

    "DMG up"

    Quality: 3

    +1.0 Damage Up

    +10% chance of a devil/angel room opening while held

    A second Pentagram will give an extra +5% chance

    Counts as 1 of 3 evil items needed towards the Leviathan transformation

      Type: Passive

      Item Pool: Boss Room, Curse Room, Devil Room, Demon Beggar, Crane Game

    * curse room pool, devil pool, devil room pool, devil deal, boss room pool, boss room item, satanic, star, red, black

  • Dr. Fetus

    ItemID: 52

    "???"

    Quality: 4

    Instead of tears, Isaac now shoots bombs from his eyes, which explode dealing damage to anything nearby

    Bomb damage = damage * 10

    Tears Down (Tear delay * 2.5)

    Bombs will also synergize with other bomb items and tear modifiers, including Sad Bombs, Mr. Mega and many more

    REPENTANCE - Dr. Fetus bombs now scale with the player's tear size and are now immune to knockback from their own explosions. The damage formula of the bombs has changed from damage * 5 + 30 to damage * 10

    UNLOCK: Unlock this item by beating Mom's Heart 9 times

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, baby, fetus, foetus, jar, white, pink, bug, dr fetus

  • Magneto

    ItemID: 53

    "Item snatcher"

    Quality: 1

    Causes pickups on the floor move towards the player

    Works across pits, but not through Key blocks

    REPENTANCE - Magneto is now capable of opening chests from a small distance. Does not apply to locked chests

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, red, horse shoe

  • Treasure Map

    ItemID: 54

    "Full visible map"

    Quality: 2

    Reveals the entire map for every floor except the secret room locations

    Does not show the icons for any unexplored rooms

    Can still help you to guess which direction the boss room is in, due to the fact that the Boss Room is usually in the room furthest away from the first room

      Type: Passive

      Item Pool: Shop, Beggar

    * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, brown, x, cross, paper

  • Mom's Eye

    ItemID: 55

    "Eye in the back of your head"

    Quality: 1

    Isaac has a random chance to fire another tear out the back of his head

    The chance to fire the second tear can improve based on your luck stat and will always activate at +2 Luck

    Synergizes very well with a lot of items. If used with Brimstone you have a 100% chance to fire a laser out the back of your head

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Passive, Tear Modifier

      Item Pool: Item Room, Challenge Room

    * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, white, red, moms eye, mom eye

  • Lemon Mishap

    ItemID: 56

    "Oops..."

    Quality: 1

    When used, drops a pool of 'lemonade' on the floor which damages any enemies that come into contact with it for 8 damage per tick

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, yellow

  • Distant Admiration

    ItemID: 57

    "Attack fly"

    Quality: 2

    Gives Isaac an orbiting fly which deals 5 contact damage to enemies per tick

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive, Orbital

      Item Pool: Item Room, Key Beggar

    * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, grey, gray

  • Book of Shadows

    ItemID: 58

    "Temporary invincibility"

    Quality: 2

    Gives the player an invulnerability effect which lasts for a 10 seconds

    Can be used to get free hits on the Blood Donation machines and Devil Beggars

    Counts as 1 of 3 book items needed towards the Bookworm transformation

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Item Room, Library

    * library pool, library room, book room pool, item room, treasure room, item room pool, white, pink

  • The Ladder

    ItemID: 60

    "Building bridges"

    Quality: 1

    Allows Isaac to walk over gaps with a width of one tile

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, the lost item pool, brown, wooden

  • Charm of the Vampire

    ItemID: 62

    "Kills heal"

    Quality: 0

    Heals half a heart after every 13 enemies killed

    Works with the Keeper for restoring coin HP

    REPENTANCE - Also gives +0.3 Damage Up

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, the lost item pool, black, grey, gray, bat

  • The Battery

    ItemID: 63

    "Stores energy"

    Quality: 2

    All spacebar items can now be 'overcharged', allowing them to be charged up twice instead of once

    The extra charges appear in yellow on top of the normal green bars

    This item works with self-recharging items

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, pink, purple

  • Steam Sale

    ItemID: 64

    "50% off"

    Quality: 2

    Items in the shop are now -50% off

    15c items are reduced to 7c. 5c pickups become 3c. 3c pickups become 2c

    Taking more than 1 steam sale reduces the price of all items even further

    This item is called Steamy Sale on PS4, PS Vita, Xbox One and Switch versions, probably due to copyright reasons

      Type: Passive

      Item Pool: Shop, Greed Miniboss, Shopkeeper

    * shop room pool, shop item pool, red, pink, white, paper

  • Anarchist Cookbook

    ItemID: 65

    "Summon bombs"

    Quality: 1

    Spawns 6 troll bombs at random locations around the room

    Bombs are effected by other passive bomb items

    Has a chance to drop from the Pride miniboss fight

    Counts as 1 of 3 book items needed towards the Bookworm transformation

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Item Room, Library, Pride Miniboss

    * Anarchist's Cookbook, Anarchists Cookbook library pool, library room, book room pool, item room, treasure room, item room pool, white, red, pink

  • The Hourglass

    ItemID: 66

    "Temporary enemy slowdown"

    Quality: 1

    When used, slows down all enemies in the current room and their projectiles for about 8 seconds

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, hour glass, hourglass, egg timer, sandbrown, glass

  • Sister Maggy

    ItemID: 67

    "Friends 'till the end"

    Quality: 0

    A familiar which follows Isaac around and shoots blood tears that deal 5 damage

    The tears appear red but have no additional damage

    Sister Maggy fires tears at a rate of 1 tear per second

    Counts as 1 of 3 familiar items needed towards the Conjoined transformation

    REPENTANCE - Sister Maggy's tear damage has been increased to 5 (from 3.5), to match its original Flash damage

      Type: Passive, Familiar

      Item Pool: Item Room, Devil Room

    * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, red, dead, baby

  • Technology

    ItemID: 68

    "Laser tears"

    Quality: 3

    Isaac's tears are replaced with a laser that has unlimited range and can only fire at right angles

    Lasers travel through enemies but not obstacles in the room

    Synergizes with most items that affect how many tears you fire (20/20, Mutant Spider etc.) or the path they take (My Reflection, Tiny Planet etc.)

    REPENTANCE - The hit detection has been improved - Technology fires in a straight line

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, red, wire, white, eye

  • Chocolate Milk

    ItemID: 69

    "Charge shots"

    Quality: 3

    Isaac can now charge shots for more damage by holding down the fire button

    At full charge, your tears do 4 times more damage

    Tears fired at the minimum possible charge do roughly 1/3 of your normal damage

    You can spam the fire button to rapid fire, however the overall damage per second will be low

    Tears down: Delay * 2.5

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, brown, glass, beaker, white

  • Growth Hormones

    ItemID: 70

    "DMG up + speed up"

    Quality: 3

    +1.0 Damage Up

    +0.2 Speed Up

    Counts as 1 of 3 syringe items needed towards the Spun transformation

      Type: Passive

      Item Pool: Boss Room, Demon Beggar

    * demon beggar pool, demon judgement pool, devil beggar pool, boss room pool, boss room item, syringe, needle, injection, purple, grey, gray

  • Mini Mush

    ItemID: 71

    "Speed + range up"

    Quality: 2

    +0.3 Speed Up

    Decreases range stat by -4.25 but increases your tear height by 1.5, increasing your actual tear range

    Causes Isaac to shrink in size (including hitbox slightly)

    Can be dropped when exploding mushrooms in the environment that are usually found in the Caves/Catacombs and in secret rooms

    Counts as 1 of 3 mushroom items needed towards the Fun Guy transformation

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, mushroom, blue, spotted

  • Rosary

    ItemID: 72

    "Faith up"

    Quality: 1

    +3 Soul Hearts

    +0.5 Tears Up

    Adds several instances of The Bible item into all item pools

    Counts as 1 of 3 angel items needed towards the Seraphim transformation

      Type: Passive

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, the lost item pool, red, beads, grey, gray, cross

  • Cube of Meat

    ItemID: 73

    "Gotta meat em all"

    Quality: 2

    An orbital which blocks shots and damages enemies it comes into contact with for 7 damage per tick

    Exclusively drops from one of the horsemen bosses

    2 cubes of meat transform the orbital into a meat head which fires blood tears which deal 3.5 damage each

    3 cubes of meat transform it into a meat boy familiar that walks around and deals 3.5 contact damage per tick to enemies

    4 cubes of meat cause the meat boy familiar to grow in size and do 5.5 damage per tick instead

    Any further cubes of meat past 4 will start the cycle again

    UNLOCK: Unlock this item by beating Mom for the first time

      Type: Passive

      Item Pool: None (Horsemen boss only)

    * red, box, square

  • A Quarter

    ItemID: 74

    "+25 coins"

    Quality: 2

    +25 Coins

    Has a very small chance to drop after destroying one of the pots that appear in the Basement and Cellar floors

    Has a chance to drop from the Super Greed miniboss fight

    UNLOCK: Unlock this item by beating Mom's Heart 8 times

      Type: Passive

      Item Pool: Devil Room, Gold Chest, Super Greed Miniboss

    * secret room pool, item room, treasure room, item room pool, 25, grey, gray, silver, devil pool, devil room pool, devil deal,

  • PhD

    ItemID: 75

    "Better pills"

    Quality: 2

    Converts most negative pills into their positive counterparts, e.g. Stat Down becomes Stat Up. Bad Trip becomes Balls of Steel. Amnesia becomes I Can See Forever etc

    Pills are identified before using them

    Drops one pill on pickup

    Heals for 2 full red hearts

    Adds 0-2 coins to the payout when you use a Blood Donation machine or IV Bag

      Type: Passive

      Item Pool: Item Room, Shop

    * shop room pool, shop item pool, item room, treasure room, item room pool, pink, yellow, paper

  • X-Ray Vision

    ItemID: 76

    "I've seen everything"

    Quality: 2

    Reveals the entrance to secret rooms and automatically opens the hole, removing the need for bombs to enter

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, xray vision, xray glasses, pink, white, black

  • My Little Unicorn

    ItemID: 77

    "Temporary badass"

    Quality: 1

    Gives Isaac invincibility and +0.28 Speed for 6 seconds

    While active you cannot fire tears, but running into enemies will deal 40 contact damage per second

    Allows free hits on the Blood Donation machines and devil beggars

      Type: Active

      Recharge Time: 4 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, white, horn

  • Book of Revelations

    ItemID: 78

    "Reusable soul protection"

    Quality: 3

    Upon use, gives Isaac an extra Soul heart

    Using this item gives you a higher chance of finding a horsemen boss at the end of the floor

    +17.5% chance of a Devil Deal opening after the boss fight

    Counts as 1 of 3 book items needed towards the Bookworm transformation

    UNLOCK: Unlock this item by beating one of the horsemen bosses for the first time

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Item Room, Library

    * library pool, library room, book room pool, item room, treasure room, item room pool, the lost item pool, purple, cross

  • The Mark

    ItemID: 79

    "DMG up"

    Quality: 3

    +1.0 Damage Up

    +0.2 Speed Up

    +1 Soul Heart

    Counts as 1 of 3 evil items needed towards the Leviathan transformation

      Type: Passive

      Item Pool: Curse Room, Devil Room, Demon Beggar

    * curse room pool, devil pool, devil room pool, devil deal, red, 666

  • The Pact

    ItemID: 80

    "DMG + tears up"

    Quality: 3

    +0.5 Damage Up

    +0.7 Tears Up

    +2 Black Hearts

    Counts as 1 of 3 evil items needed towards the Leviathan transformation

      Type: Passive

      Item Pool: Devil Room, Curse Room, Demon Beggar

    * curse room pool, devil pool, devil room pool, devil deal, piece of paper, bloody paper, contract, red, drip

  • Dead Cat

    ItemID: 81

    "9 lives"

    Quality: 3

    Isaac's health is set to 1 and he also gains 9 extra lives

    Each time Isaac dies, he will respawn with 1 Health

    Has a chance to drop from the Super Pride mini boss

    The floating Dead Cat head that follows you will disappear when you are on your last life (Very useful for The Lost)

    Counts as 1 of 3 cat items needed towards the Guppy transformation

      Type: Passive

      Item Pool: Devil Room, Curse Room, Red Chest, Super Pride Miniboss

    * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal

  • Lord of the Pit

    ItemID: 82

    "Demon wings"

    Quality: 3

    Gives Isaac demon wings and the ability to fly

    +0.3 Speed Up

      Type: Passive

      Item Pool: Devil Room, Demon Beggar

    * devil pool, devil room pool, devil deal, the lost item pool, cross, upside down, red, black

  • The Nail

    ItemID: 83

    "Temporary demon form"

    Quality: 3

    Each use of this item gives +0.7 Damage Up, -0.18 Speed Down and the ability to destroy most obstacles for the current room.

    Each use also gives +0.5 Black Hearts, however this is stays between rooms unlike the other effects

    Allows Isaac to deal 40 contact damage to enemies for the current room. Does not prevent Isaac from taking contact damage

    All the above effects are only active when the item is used for the current room

    Counts as 1 of 3 evil items needed towards the Leviathan transformation

    REPENTANCE - The Nail's temporary damage bonus has been increased, and is now able to stack with itself. Now grants a half black heart upon use instead of a full soul heart.

    UNLOCK: Unlock this item by beating the Boss Rush with Azazel

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Devil Room, Demon Beggar

    * devil pool, devil room pool, devil deal, grey, gray, bloody

  • We Need To Go Deeper

    ItemID: 84

    "Reusable level skip"

    Quality: 0

    Spawns a trapdoor at Isaac's feet which allows him to travel to the next floor

    The trapdoor has a 10% chance to become a Crawl Space or Black Market

    In Sheol, Cathedral, Chest and Dark Room this item either opens a Crawl Space, or does nothing

    Cannot spawn a trapdoor directly infront of a secret room entrance

    Can destroy rocks if used when Isaac is flying over a rock

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Secret Room, Devil Room

    * secret room pool, devil pool, devil room pool, devil deal, silver, grey, gray, dig, spade, shovel

  • Deck of Cards

    ItemID: 85

    "Reusable card generator"

    Quality: 1

    Gives Isaac a random tarot card on use

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Item Room, Shop

    * shop room pool, shop item pool, item room, treasure room, item room pool, brown, pink

  • Monstro's Tooth

    ItemID: 86

    "Summon monstro"

    Quality: 1

    When used, spawns a Monstro which will jump on a random enemy in the room, dealing 120 damage and destroying nearby obstacles

    UNLOCK: Unlock this item by beating the Basement II for the first time

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, white, grey, gray, bloody, monstros tooth, monstro tooth

  • Loki's Horns

    ItemID: 87

    "Cross tears"

    Quality: 1

    Everytime you fire a tear, there is a chance that you will also fire three more tears in all cardinal directions

    The chance to fire 4-way tears is affected by your luck stat and at +7 Luck it will activate every time

    UNLOCK: Unlock this item by beating Lokii for the first time

      Type: Passive, Tear Modifier

      Item Pool: Item Room, Demon Beggar

    * item room, treasure room, item room pool, grey, gray, devil, lokis horns loki horns

  • Little Chubby

    ItemID: 88

    "Attack buddy"

    Quality: 1

    A familiar that follows Isaac and charges forwards, dealing 3.5 damage per tick to any enemies it comes into contact with

    REPENTANCE - The damage tick rate on Little Chubby has been increased

    UNLOCK: Unlock this item by beating the Caves II for the first time

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, yellow, smile, face, bug

  • Spider Bite

    ItemID: 89

    "Slow effect"

    Quality: 2

    Tears now have a chance of slowing enemies and their projectiles for 2.5 seconds

    The chance to slow enemies is affected by your luck stat and at +15 Luck it will activate every time

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, black, grey, gray, red, bug

  • The Small Rock

    ItemID: 90

    "DMG up"

    Quality: 3

    +1.0 Damage Up

    +0.2 Tears Up

    -0.2 Speed Down

    Has a chance to drop when exploding a tinted rock

    UNLOCK: Unlock this item by destroying 100 tinted rocks

      Type: Passive

      Item Pool: None (Tinted rock only)

    * tinted rock, marked rock, grey, gray, lump, white

  • Spelunker Hat

    ItemID: 91

    "See-through doors"

    Quality: 2

    Reveals adjacent room types, this includes revealing if you're next to a Secret Room or Super Secret Rooms

    Gives Isaac a slight glow when Curse of Darkness is active

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, spelunky, miner, mining, helpmet, light, purple, olmec yama grey, gray, lamp

  • Super Bandage

    ItemID: 92

    "+2 hearts"

    Quality: 2

    +1 HP Up

    +2 Soul Hearts

    Heals one red heart container when picked up

    UNLOCK: Unlock this item by making a Super Bandage Girl

      Type: Passive

      Item Pool: Item Room, Boss Room, pink, plaster, sticker

    * boss room pool, boss room item, item room, treasure room, item room pool, the lost item pool

  • The Gamekid

    ItemID: 93

    "Temporary Man-Pac"

    Quality: 2

    When used Isaac transforms into pacman, which makes him invincible for 6 seconds and does 40 contact damage to enemies per chomp

    Everytime you 'eat' 2 enemies, you regain 1/2 heart of red health

    You can't shoot tears while the effect is active

    UNLOCK: Unlock this item by visiting 10 arcades

      Type: Active

      Recharge Time: 4 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, gameboy, grey, gray, white

  • Sack of Pennies

    ItemID: 94

    "Gives money"

    Quality: 1

    A bag that floats around following Isaac and drops a random coin every 2 rooms

    UNLOCK: Unlock this item by beating Isaac with Cain

      Type: Passive, Familiar

      Item Pool: Item Room

    * secret room pool, item room, treasure room, item room pool, bag, purple, pouch

  • Robo-Baby

    ItemID: 95

    "Friends till the bzzzttt"

    Quality: 1

    A familiar which follows Isaac and shoots lasers, similar to the Technology item

    Robo-Baby's laser is spectral and piercing (It will pass through rocks and objects in the environment)

    Robo-Baby's lasers deal 3.5 damage per hit

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, robo baby, robot baby, white, grey, gray, silver, red

  • Little C.H.A.D

    ItemID: 96

    "Gives kisses"

    Quality: 2

    A familiar which follows Isaac and drops half a red heart every 3 rooms

    UNLOCK: Unlock this item by beating the Caves 30 times and defeating C.H.A.D

      Type: Passive, Familiar

      Item Pool: Item Room, C.H.A.D. Boss

    * lil chad, little chad, item room, treasure room, item room pool, the lost item pool, red, smile, face, bug

  • The Book of Sin

    ItemID: 97

    "Reusable item generator"

    Quality: 2

    Spawns a random pickup on the floor

    Any pickups are possible from this item, including Bombs, hearts, keys, coins, pills, batteries, tarot cards, runes etc

    Counts as 1 of 3 book items needed towards the Bookworm transformation

    UNLOCK: Unlock this item by beating each of the Seven Sins once

      Type: Active

      Recharge Time: 4 rooms

      Item Pool: Item Room, Library, Devil Room

    * library pool, library room, book room pool, devil pool, devil room pool, devil deal, item room, treasure room, item room pool, red 7 book, grey, gray, black

  • The Relic

    ItemID: 98

    "Soul generator"

    Quality: 4

    A blue cross that follows Isaac and drops a soul heart every 7-8 rooms

    REPENTANCE - The Relic now generates soul hearts less frequently

    UNLOCK: Unlock this item by beating the Isaac boss with Maggy

      Type: Passive, Familiar

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, the lost item pool

  • Little Gish

    ItemID: 99

    "Sticky friend"

    Quality: 2

    A familiar that follows Isaac and fires black tar tears, which slow enemy movement and projectile speed for a few seconds

    Little Gish's tears do 3.5 damage

    Little Gish fires tears at a rate of 1 tear per second

    A Guaranteed drop from the Gish boss fight

    UNLOCK: Unlock this item by beating the Depths 20 times and killing the Gish boss

      Type: Passive, Familiar

      Item Pool: Item Room, Gish Boss

    * item room, treasure room, item room pool, grey, gray, yellow, eyes, face

  • Little Steven

    ItemID: 100

    "Psychic friend"

    Quality: 1

    A familiar that follows Isaac and fires homing tears that deal 3.5 damage each

    Has a high chance to drop from the Steven boss fight

    Little Steven fires tears at a rate of 1 tear per second with a slightly longer range than other familiars

    Counts as 1 of 3 familiar items needed towards the Conjoined transformation

    UNLOCK: Unlock this item by killing the Steven boss for the first time

      Type: Passive, Familiar

      Item Pool: Item Room, Steven Boss

    * boss room pool, boss room item, item room, treasure room, item room pool, black, baby, white, eyes

  • The Halo

    ItemID: 101

    "All stats up"

    Quality: 2

    +1 HP Up

    +0.3 Damage Up

    +0.2 Tears Up

    +0.25 Range Up

    +0.3 Speed Up

    +0.5 Tear Height

    Heals one red heart container when picked up

    Counts as 1 of 3 angel items needed towards the Seraphim transformation

    UNLOCK: Unlock this item by killing Mom (Mom's Foot or Mom's Heart) using The Bible

      Type: Passive

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, boss room pool, boss room item, item room, treasure room, item room pool, yellow, golden, ring, circle

  • Mom's Bottle of Pills

    ItemID: 102

    "Reusable pill generator"

    Quality: 1

    When used, gives Isaac a random pill

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Item Room, Shop, Challenge Room, Beggar, Demon Beggar

    * dungeon room, blood challenge room, arena pool, demon beggar pool, demon judgement pool, devil beggar pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, item room, treasure room, item room pool, yellow, red, blue, medicine, jar, drug, moms bottle of pills

  • The Common Cold

    ItemID: 103

    "Poison damage"

    Quality: 1

    Tears now have a random chance to apply a poison effect, causing double your tear damage per tick to enemies over time

    The chance to fire poison shots is affected by your luck stat and at +12 Luck it will activate every time

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, green, snot, booger, ball, slime

  • The Parasite

    ItemID: 104

    "Split shot"

    Quality: 2

    Isaac's tears now split into two upon contact with enemies or the environment

    Tears that split off from the main tear do less damage (tear damage * 0.5)

    Tears can keep splitting if they still have range and damage above 1

    UNLOCK: Unlock this item by collecting two of the following items: Bob's Rotten Head, Dead Cat, Cricket's Head, Tammy's Head

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, pink, slug, bug, face

  • The D6

    ItemID: 105

    "Reroll your destiny"

    Quality: 4

    When used, replaces all pedestal items in the current room with another random item. Re-rolled items pick from the current room's item pool

    Isaac starts with this item after it is unlocked

    UNLOCK: Unlock this item by defeating the Isaac boss with Blue Baby

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, dice pip, starting, pink, red, cube

  • Mr. Mega

    ItemID: 106

    "Blast damage"

    Quality: 2

    +5 Bombs

    Bombs now do 185 damage (up from 100) and have a larger blast radius

    Can be found in the secret room

    Has a chance to drop from the Super Wrath miniboss fight

    REPENTANCE - Mr. Mega bombs buffed from 110 to 185 each

    UNLOCK: Unlock this item by destroying 10 tinted rocks

      Type: Passive

      Item Pool: Item Room, Bomb Beggar, Super Wrath Miniboss

    * boss rush pool, boss rush room, secret room pool, item room, treasure room, item room pool, dungeon room, blood challenge room, arena pool, slackaholicus, grey, gray, face

  • Pinking Shears

    ItemID: 107

    "Cut and run"

    Quality: 3

    Cuts Isaac's head from his body for the current room, allowing him to fly and leaving the decapitated body to run around attacking enemies for 5.5 damage per tick

      Type: Active

      Recharge Time: 4 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, scissors, cutters, snip, scissors, silver, grey, gray

  • The Wafer

    ItemID: 108

    "Damage resistance"

    Quality: 4

    All damage taken is reduced to half a heart

    Damaged reduction is reduced from every source in the game except Devil Deals and health down pills

    Does not prevent death (i.e. Suicide King or using The Bible on Isaac, ??? or Satan)

    The Wafer becomes most effective in the Womb and beyond where enemies all deal a whole heart of damage

    The Wafer causes the Sharp Plug item to only cost 1/2 a heart per use

    Has no effect with the Keeper - there's no such thing as half a coin health point

      Type: Passive

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, communion, the lost item pool, circle, cross, white, yellow

  • Money = Power

    ItemID: 109

    "$$$ = DMG"

    Quality: 3

    +0.04 Damage Up for every coin you currently have

    At 99 coins this item gives +3.96 Damage Up

    +0.04 per coin is the amount added before the damage formula is calculated, as this is the only way to show a consistent amount of damage given. You may see more or less than this on the Found HUD overlay, however this number varies based on your other damage increasing items

      Type: Passive

      Item Pool: Item Room, Devil Room

    * item room, treasure room, item room pool, money is power, dollar, red, grey, gray,

  • Mom's Contacts

    ItemID: 110

    "Freeze effect"

    Quality: 3

    Tears now have a random chance to freeze enemies in place

    The chance to freeze enemies is affected by your luck stat

    +0.25 Range Up

    +0.5 Tear Height

    Chance to activate increases with luck, up to around 50% chance at +20 luck

    Counts as 1 of 3 mom items needed towards the Mom transformation

    UNLOCK: Unlock this item by collecting 3 'Mom' items in one playthrough

      Type: Passive

      Item Pool: Item Room, Challenge Room

    * item room, treasure room, item room pool, dungeon room, blood challenge room, arena pool, pink, red, eye, glow moms contacts mom contact

  • The Bean

    ItemID: 111

    "Toot on command"

    Quality: 0

    Upon use, this item causes Isaac to fart and poison any enemies in close proximity

    The Bean deals 5 damage, then poisons enemies for 6 total ticks of damage

    The poison deals your current tear damage per tick

      Type: Active

      Recharge Time: 1 room

      Item Pool: Item Room, Beggar

    * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, treasure room, item room pool, team bean, #teambean, brown, kidney

  • Guardian Angel

    ItemID: 112

    "Extra protection"

    Quality: 2

    An orbital which does 7 contact damage per tick, blocks shots and increases the speed of all other orbitals

    Counts as 1 of 3 angel items needed towards the Seraphim transformation

    UNLOCK: Unlock this item by beating Satan with Maggy

      Type: Passive, Orbital

      Item Pool: Angel Room

    * angel room pool, god room pool, angel room item, baby, wings

  • Demon Baby

    ItemID: 113

    "Auto-turret friend"

    Quality: 2

    A familiar which follows Isaac and automatically fires tears that deal 3 damage each at any enemies in close range

    UNLOCK: Unlock this item by beating the Dark Room with Azazel

      Type: Passive, Familiar

      Item Pool: Item Room, Devil Room

    * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, dead, black, grey, gray, horns

  • Mom's Knife

    ItemID: 114

    "Stab stab stab"

    Quality: 4

    Tears are replaced with a knife which can be charged and thrown in a boomerang style action

    The knife can also do damage without being thrown as a close range melee weapon

    When used as a melee weapon, Mom's Knife deals your tear damage * 2 per tick

    At the furthest point from Isaac the knife deals your tear damage * 6

    Counts as 1 of 3 mom items needed towards the Mom transformation

    UNLOCK: Unlock this item by beating Satan with Isaac

      Type: Passive, Tear Modifier

      Item Pool: Item Room, Devil Room, Challenge Room

    * dungeon room, blood challenge room, arena pool, devil pool, devil room pool, devil deal, item room, treasure room, item room pool, grey, gray, silver

  • Ouija Board

    ItemID: 115

    "Spectral tears"

    Quality: 2

    Gives Isaac spectral tears which allows them to travel through objects in the environment (i.e. rocks)

      Type: Passive

      Item Pool: Item Room, Devil Room

    * item room, treasure room, item room pool, luigi board, weeja board, paper, grown

  • 9 Volt

    ItemID: 116

    "Quicker charge"

    Quality: 2

    Automatically gives you 1 bar of charge after using your spacebar item

    Fully recharges your current spacebar item when picked up

    Causes the Sharp Plug item to become useless for 2+ room recharge items, due to the fact that you can never have 0 charge on your spacebar item

    Any items which are normally a 1 room recharge are now timed instead

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, battery, black, brown

  • Dead Bird

    ItemID: 117

    "Protective buddy"

    Quality: 0

    When Isaac takes damage, the dead bird will spawn and attack nearby enemies in the current room for 2 damage per tick

    Eve starts with this item

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, the lost item pool, starting, grey, gray

  • Brimstone

    ItemID: 118

    "Blood laser barrage"

    Quality: 4

    Tears are replaced with the ability to charge and fire a powerful laser that travels in a straight line across the room, dealing a lot of damage (damage * 9) to any enemies it comes into contact with

    Does not directly affect your Damage stat but hits enemies 9 times per charge, spawning Guppy flies with every hit

    Synergizes very well with a lot of items including Tammy's Head, Tiny Planet, Inner Eye (Triple Shot), Mutant Spider (Quad Shot) and many others

    Counts as 1 of 3 evil items needed towards the Leviathan transformation

    REPENTANCE - If you somehow manage to get a second Brimstone, the laser becomes massive and deals double damage

    REPENTANCE - Each laser only hits 9 times, down from 13

      Type: Passive, Tear Modifier

      Item Pool: Devil Room

    * devil pool, devil room pool, devil deal, infinity, red, black

  • Blood Bag

    ItemID: 119

    "HP up"

    Quality: 2

    +1 HP Up

    +0.3 Speed Up

    Heals for 5 full red hearts

    Has a chance to drop while playing any Blood Donation machine

    UNLOCK: Unlock this item by playing the Blood Donation machine 30 times

      Type: Passive

      Item Pool: None (Blood Donation machine only)

    * , the lost item pool, red, white

  • Odd Mushroom (Thin)

    ItemID: 120

    "Fire rate up"

    Quality: 3

    Gives you a high rate of fire in exchange for a damage down

    +1.7 Tears Up

    +0.3 Speed Up

    Damage Down (damage * 0.9 - 0.4)

    Counts as 1 of 3 mushroom items needed towards the Fun Guy transformation

      Type: Passive

      Item Pool: Item Room, Secret Room, brown, purple, grey, gray

    * secret room pool, item room, treasure room, item room pool

  • Odd Mushroom (Large)

    ItemID: 121

    "DMG up"

    Quality: 2

    +1 HP Up

    +1.0 Damage Up

    +0.25 Range Up

    -0.2 Speed Down

    +0.5 Tear Height

    Heals one red heart container when picked up

    Counts as 1 of 3 mushroom items needed towards the Fun Guy transformation

    REPENTANCE - Odd Mushroom (thick) is now a larger damage increase (equal to that of Steven/Pentagram), but now also a larger speed downgrade (from -0.1 to -0.2)

      Type: Passive

      Item Pool: Item Room, Secret Room

    * secret room pool, item room, treasure room, item room pool, purple, pink, brown, thick odd mushroom thick

  • Whore of Babylon

    ItemID: 122

    "Curse up"

    Quality: 2

    When you only have half a red heart remaining or less, you enter a curse state which adds +1.5 damage and +0.3 speed

    When playing as Eve, this item activates with one FULL heart remaining or less AND also removes her 0.75 damage multiplier, raising it up to 1.0

    The effect is permanently active for characters with no red hearts (e.g. Blue Baby, The Lost)

    One of Eve's starting items

      Type: Passive

      Item Pool: Devil Room, Demon Beggar

    * devil pool, devil room pool, devil deal, red, black, star, moon

  • Monster Manual

    ItemID: 123

    "Temporary buddy generator"

    Quality: 0

    When used, gives a random familiar for the rest of the room

    It can spawn familiars you haven't unlocked yet!

    REPENTANCE - Monster Manual familiars now persist for the entire floor. Charge time has been increased to 6 (from 3).

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Item Room, Devil Room, Library

    * item room, treasure room, item room pool, devil pool, devil room pool, devil deal, book, brown, blue, monster manuel, manaul

  • Dead Sea Scrolls

    ItemID: 124

    "It's a mystery"

    Quality: 1

    Upon use, the dead sea scrolls gives a random spacebar item effect

    An item that can be found in the Angel room

    REPENTANCE - Dead Sea Scrolls now displays the name of the given effect, and can no longer give Kamikaze.

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, paper, roll, white

  • Bobby - Bomb

    ItemID: 125

    "Friends till the end"

    Quality: 2

    +5 Bombs

    All of Isaac's bombs now having a homing effect when placed on the floor

      Type: Passive

      Item Pool: Item Room, Bomb Beggar

    * boss rush pool, boss rush room, item room, treasure room, item room pool, bomb beggar, dead, grey, gray, feet bobby bomb

  • Razor Blade

    ItemID: 126

    "Feel my pain"

    Quality: 0

    When used, deals damage to Isaac in exchange for +1.2 damage up which lasts for the current room

    Eve starts with this item after donating 439 coins to the Greed Donation Machine.

    UNLOCK: Unlock this item by beating Satan with Eve

      Type: Active

      Recharge Time: Instant

      Item Pool: Devil Room, Demon Beggar

    * devil pool, devil room pool, devil deal, the lost item pool, starting, silver, grey, gray

  • Forget Me Now

    ItemID: 127

    "I don't remember..."

    Quality: 3

    Upon use, this item refreshes the current floor with brand new rooms, monsters and items, as if you had entered a new floor

    UNLOCK: Unlock this item by beating Satan with Blue Baby

      Type: Active

      Recharge Time: Instant (One time use)

      Item Pool: Item Room, Secret Room, Devil Room, Demon Beggar

    * secret room pool, item room, treasure room, item room pool, pill, tablet, drug, white, purple

  • Forever Alone

    ItemID: 128

    "Attack fly"

    Quality: 1

    An orbiting fly which deals 2 contact damage per tick to enemies

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive, Orbital

      Item Pool: Item Room

    * item room, treasure room, item room pool, blue

  • Bucket of Lard

    ItemID: 129

    "HP up"

    Quality: 1

    +2 Health Up

    -0.2 Speed Down

    Has a chance to drop from the Super Gluttony miniboss fight

      Type: Passive

      Item Pool: Item Room, Super Gluttony Miniboss

    * item room, treasure room, item room pool, the lost item pool, white, grey, gray, tub

  • A Pony

    ItemID: 130

    "Flight + dash attack"

    Quality: 2

    Allows Isaac to fly while the Pony is held

    Sets your speed stat to 1.5 if it isn't already that high

    When the active attack is used, Isaac will dash across the screen dealing scaling contact damage to anything he hits

    Drops from the Headless Horseman boss fight

    REPENTANCE - A Pony's charge time has been reduced to 2 (from 4). Ram damage formula has changed to damage * 4 + 28 (previously dealt a static 40 damage). The charge direction now allows for a minor amount of control

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: None (Headless horseman only)

    * headless horseman, headless horsemen, red, grey, gray

  • Bomb Bag

    ItemID: 131

    "Gives bombs"

    Quality: 2

    A bag of bombs that will drop a bomb pickup every 2 rooms

    UNLOCK: Unlock this item by beating Satan with Cain

      Type: Passive, Familiar

      Item Pool: Item Room

    * boss rush pool, boss rush room, secret room pool, item room, treasure room, item room pool, sack, pouch, blue, purple

  • A Lump of Coal

    ItemID: 132

    "My Xmas present"

    Quality: 3

    Tears gain a damage up and increase in size based on the distance they travel

    The length of a normal room roughly gives +6 damage, but this can be higher with double rooms or Tiny Planet

    This item synergises with beam items such as Brimstone and Tech, allowing them to do more damage the further away the enemy is

      Type: Passive

      Item Pool: None (Krampus only)

    * krampus, grey, gray

  • Guppy's Paw

    ItemID: 133

    "Soul converter"

    Quality: 3

    When used, removes one heart container and gives you 3 soul hearts

    Bone hearts cannot be converted

    Counts as 1 of 3 cat items needed towards the Guppy transformation

      Type: Active

      Recharge Time: Instant

      Item Pool: Devil Room, Curse Room, Red Chest

    * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, the lost item pool, cat, bone, pink, grey, gray, guppys paw, guppy paw

  • Guppy's Tail

    ItemID: 134

    "Cursed?"

    Quality: 2

    Gives a 1/3 chance for room clear rewards to become a normal or locked chest, and a 1/3 chance to reward nothing at all

    Doesn't affect coins dropped after waves in Greed Mode

    Counts as 1 of 3 cat items needed towards the Guppy transformation

      Type: Passive

      Item Pool: Devil Room, Curse Room, Red Chest

    * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, black, white, gray, grey, guppys tail, guppy tail

  • IV Bag

    ItemID: 135

    "Portable blood bank"

    Quality: 1

    Upon use, the IV Bag takes half a red heart and spawns 1-3 coins (the same effect as a blood donation machine)

    Can drop from a blood donation machine after playing it

    In the Womb and beyond this deals 1 full heart of damage

    If no red hearts exist, other types of hearts are consumed instead

    With the Keeper this is changed to spawning 0-1 coins per use instead

      Type: Active

      Recharge Time: Instant

      Item Pool: None (Blood donation machine only)

    * , the lost item pool, red, white

  • Best Friend

    ItemID: 136

    "Friends 'till the end"

    Quality: 1

    Places a decoy on the floor which attracts enemies and explodes after a period of time

    When it explodes, it deals 185 damage to everything in radius (Same damage as Mr Mega bombs)

    REPENTANCE - Damage buffed from 110 to 185

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, worst friend, dead, baby, pink

  • Remote Detonator

    ItemID: 137

    "Remote bomb detonation"

    Quality: 1

    +5 Bombs

    Bombs no longer automatically explode and will only do so when you activate the remote detonator

    Can be used to detonate Dr. Fetus bombs early

      Type: Active

      Recharge Time: Instant

      Item Pool: Item Room, Shop, Bomb Beggar

    * boss rush pool, boss rush room, shop room pool, shop item pool, item room, treasure room, item room pool, red, boom, tnt

  • Stigmata

    ItemID: 138

    "DMG + HP up"

    Quality: 2

    +1 HP Up

    +0.3 Damage Up

    Heals one red heart container when picked up

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, wooden, cross, brown

  • Mom's Purse

    ItemID: 139

    "More trinket room"

    Quality: 3

    Isaac can now hold two trinkets at the same time

    Drops a random trinket on the floor when picked up

    Allows you to pick up more trinkets while also holding The Tick

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, purple, pink, bag

  • Bob's Curse

    ItemID: 140

    "Poison bombs"

    Quality: 1

    All of Isaac's bombs now leave a poison effect on any enemies within the blast radius

    +5 Bombs

    As well as dealing the standard 60 damage for a bomb, it will apply a Damage over Time effect that does 4 or 6 damage per tick

    Has a chance to drop from the Super Sloth miniboss fight

    Counts as 1 of 3 poison items needed towards the Bob transformation

    REPENTANCE - Bob's Curse bombs now leave behind a gas cloud that poisons enemies that move through it.

      Type: Passive

      Item Pool: Item Room, Super Sloth Miniboss, Bomb Beggar

    * boss rush pool, boss rush room, item room, treasure room, item room pool, bob sloth, bomb beggar, green, dead, face

  • Pageant Boy

    ItemID: 141

    "Ultimate grand supreme"

    Quality: 0

    Spawns 7 random coins around Isaac on the floor

    Isaac wears a pink crown on his head

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, dtQt, dtphase, crown, nocrown, yescrown, diana, princezzxdiana, pink, purple, hat

  • Scapular

    ItemID: 142

    "You have been blessed"

    Quality: 2

    Once per room when you are damaged down to your final half a heart, you gain 1 soul heart

    Re-entering a room allows this effect to be triggered again

    REPENTANCE - Scapular won't grant its soul heart if the player is attempting to proc it with certain heart donation mechanics (such as IV Bag)

      Type: Passive

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, the lost item pool, brown, white, cross

  • Speed Ball

    ItemID: 143

    "Speed + shot speed up"

    Quality: 2

    +0.3 Speed Up

    +0.2 Shot Speed Up

    Counts as 1 of 3 syringe items needed towards the Spun transformation

      Type: Passive

      Item Pool: Item Room, Boss Room, Demon Beggar

    * demon beggar pool, demon judgement pool, devil beggar pool, boss room pool, boss room item, item room, treasure room, item room pool, syringe, needle, injection, white

  • Bum Friend

    ItemID: 144

    "He's Greedy"

    Quality: 0

    A beggar who follows Isaac around and automatically picks up nearby coins

    After picking up 6 coins he will drop a random pickup, e.g. hearts, keys, bombs, coins, pills, cards, trinkets etc

    After the first drop, he has a 67% chance to drop a pickup after 3 coins and a 33% chance to drop a pickup after 4 coins

    Counts as 1 of 3 bum items needed towards the Super Bum transformation

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, baby, pink

  • Guppy's Head

    ItemID: 145

    "Reusable fly hive"

    Quality: 3

    When used, spawns between 2-4 blue flies

    Blue Flies do double your tear damage

    Counts as 1 of 3 cat items needed towards the Guppy transformation

      Type: Active

      Recharge Time: 1 room

      Item Pool: Devil Room, Curse Room, Red Chest, Gold/Stone Chest

    * curse room pool, red chest pool, red chest item pool, golden chest pool, gold chest pool, devil pool, devil room pool, devil deal, dead, cat, grey, gray, guppy head, guppys head

  • Prayer Card

    ItemID: 146

    "Reusable eternity"

    Quality: 3

    Gives Isaac an eternal heart when used

    Taking an eternal heart to the next floor or collecting two on the same floor gives you an extra heart container

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, the lost item pool, white, yellow, blue

  • Notched Axe

    ItemID: 147

    "Rocks didn't stand a chance"

    Quality: 0

    When activated, Isaac takes out the axe and gives you the ability to break rocks and damage enemies with it

    It has a limited amount of uses per floor, decreasing with every hit that connects with a rock/enemy

    Cannot break the stone blocks which appear in the environment

      Type: Active

      Recharge Time: At the start of each new floor

      Item Pool: Shop, Crane Game

    * item room, treasure room, item room pool, minecraft, brown, grey, gray, silver

  • Infestation

    ItemID: 148

    "They grow inside"

    Quality: 0

    When Isaac gets hit, 2-6 blue flies will randomly spawn

    Blue Flies do double your tear damage

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

    REPENTANCE - Buffed, it used to spawn 1-3 flies each time

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, the lost item pool, bug, yellow, face

  • Ipecac

    ItemID: 149

    "Explosive shots"

    Quality: 4

    Isaac's tears are replaced with explosive poison bombs, which will arc upwards and explode on contact with the floor, dealing huge damage and leaving a poison effect on enemies in range

    Ipecac shots are given a flat +40 Damage on top of the normal 3.5 base damage

    Tears Down (Tear delay * 2 + 10)

    +13.0 Tear Height

    Shots will damage Isaac if he is in the blast radius when they explode

    Counts as 1 of 3 poison items needed towards the Bob transformation

    REPENTANCE - Ipecac explosion size now scales with tear size

    UNLOCK: Unlock this item by beating Mom's Heart 6 times

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, jar, bottle, purple, label

  • Tough Love

    ItemID: 150

    "Tooth shot"

    Quality: 3

    Isaac has a random chance to fire a tooth shot instead of a tear sometimes

    Teeth shots deal damage equal to your tear damage * 3.2

    The chance to fire a tooth is affected by your luck stat and at +9 Luck it will activate every time

    Synergizes well with some tear modifiers such as Ipecac, which causes it to do massive damage

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, knuckle, dusters, four, silver, grey, gray, brass knuckles

  • The Mulligan

    ItemID: 151

    "They grow inside"

    Quality: 3

    Isaac has a 1/6 chance to spawn a blue fly when one of his tears hits an enemy

    Blue Flies do double your tear damage

    The chance to activate this effect is not changed with your Luck stat

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, heart

  • Technology 2

    ItemID: 152

    "Laser"

    Quality: 2

    Isaac now also has a laser with unlimited range which fires continuously. Tears continue to fire from your left eye

    The laser deals damage equal to 1/7th of your tear damage, but very rapidly

    The laser can apply status effects (e.g. Poison) rapidly due to how often it hits

    REPENTANCE - The -65% Damage down has been removed! Also the hit detection has been improved - Technology fires in a straight line

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, silver, gray, grey, red, machine

  • Mutant Spider

    ItemID: 153

    "Quad Shot"

    Quality: 3

    Tears now shoot 4 at a time (Quad Shot)

    Tears Down significantly (Tear delay * 2.1 + 3)

    Synergizes well with a lot of tear effects - e.g. with Brimstone you get 4 lasers

    Counts as 1 of 3 spider items needed towards the Spider Baby transformation

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, green, black

  • Chemical Peel

    ItemID: 154

    "DMG up"

    Quality: 1

    +2 Damage Up for tears fired from Isaac's left eye

    If playing as Cain or you have an item which modifies which eye you fire tears from, each shot has a 50% chance to do +2 Damage

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, poison, green, brown, bottle, jar, danger

  • The Peeper

    ItemID: 155

    "Plop!"

    Quality: 0

    Gives Isaac an eye companion that floats around the room and deals 8 damage per tick on contact with enemies

    Damage from Isaac's left eye deal roughly +35% damage

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, red, white

  • Habit

    ItemID: 156

    "Item martyr"

    Quality: 3

    When you take damage, this item recharges one room's worth of charge to your spacebar item

    For example, with the D6 you would need to take damage 6 times to fully recharge it

      Type: Passive

      Item Pool: Shop, Angel Room

    * angel room pool, god room pool, angel room item, shop room pool, shop item pool, the lost item pool, white, black

  • Bloody Lust

    ItemID: 157

    "RAGE!"

    Quality: 3

    Each time you take damage, you gain a damage up which lasts for the rest of the floor and turn a darker red colour each time

    After taking 6 hits Bloody Lust doesn't give you any further damage increases

    Damage given for each hit increases as follows: +0.5, +0.7, +0.9, +1.1, +1.3, +1.5

    Samson starts with this item

    REPENTANCE - The damage increments have changed slightly

    UNLOCK: Unlock this item by beating the Isaac boss with Samson

      Type: Passive

      Item Pool: Item Room, Devil Room

    * item room, treasure room, item room pool, the lost item pool, starting, red, blood, drop

  • Crystal Ball

    ItemID: 158

    "I see my future"

    Quality: 2

    Upon use, reveals the map and gives the player a random tarot card, mystic rune or soul heart

    Does not reveal the location of Secret or Super Secret rooms

    Has a chance to drop from playing a fortune machine

    Guarantees a Planetarium if an item room has been skipped, otherwise +15% chance for Planetariums to spawn while held. After entering a Planetarium the chance goes back to 1%. The floor generation can fail and cause the guaranteed Planetarium to not spawn sometimes.

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: None (Fortune machine only)

    * item room, treasure room, item room pool, white, purple

  • Spirit of the Night

    ItemID: 159

    "Scary"

    Quality: 3

    Gives Isaac the ability to fly and spectral tears

    Counts as 1 of 3 evil items needed towards the Leviathan transformation

      Type: Passive

      Item Pool: Devil Room, Demon Beggar

    * devil pool, devil room pool, devil deal, red, crescent, moon, drop, black

  • Crack The Sky

    ItemID: 160

    "Holy white death"

    Quality: 2

    Creates 5 beams of light from the sky that deal damage equal to your tear damage + 20 to any enemies which come into contact with them

    The beams have a high chance to spawn on top of enemies where possible

      Type: Active

      Recharge Time: 4 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, feather, white, arrow

  • Ankh

    ItemID: 161

    "Eternal life?"

    Quality: 2

    Upon death, the player respawns as Blue Baby with three Soul hearts

    This is a one time use item and all new heart containers will be soul hearts

    Can be used to unlock some of Blue Baby's secrets before having the character available

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, black, grey, gray, extra life, egypt, grey, gray

  • Celtic Cross

    ItemID: 162

    "You feel blessed"

    Quality: 1

    Upon taking damage, you have a 20% chance to gain an invulnerability shield for 7 seconds

    The chance to gain a shield is affected by your luck stat and at +27 Luck it will activate every time

    UNLOCK: Unlock this item by beating the Chest with Maggy

      Type: Passive

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, the lost item pool, grey, gray

  • Ghost Baby

    ItemID: 163

    "Spectral buddy"

    Quality: 1

    A familiar which follows Isaac and shoots spectral tears that deal 3.5 damage

    Ghost Baby fires tears at a rate of 1 tear per second

    Can drop while destroying skulls in the Depths and Necropolis floors

      Type: Passive, Familiar

      Item Pool: Item Room, Devil Room

    * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, white, spoopy

  • The Candle

    ItemID: 164

    "Reusable flame"

    Quality: 2

    A spacebar item which allows Isaac to fire a blue flame that damages anything in its path for 23 damage per tick

    Can cause up to a total of 276 potential damage

    The flame destroys enemy shots, making it useful for bullet hell bosses

    UNLOCK: Unlock this item by donating 900 coins to the Shop

      Type: Active

      Recharge Time: Timed (A few seconds)

      Item Pool: Shop

    * shop room pool, shop item pool, blue candle, grey, gray, silver, lamp, lantern

  • Cat-O-Nine-Tails

    ItemID: 165

    "Shot speed up + DMG up"

    Quality: 3

    +1.0 Damage Up

    +0.23 Shot Speed Up

    An item only found in the Boss room pool

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, grey, gray, whip, cat o nine tails catonine tails

  • D20

    ItemID: 166

    "Reroll the basics"

    Quality: 2

    Upon use, re-rolls all pickup consumables in the current room into another random kind of pickup

    This includes all types of pickup such as hearts, bombs, keys, coins, pills, tarot cards, chests, trinkets etc

    UNLOCK: Unlock this item by beating the Chest with Isaac

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, dice pip, red

  • Harlequin Baby

    ItemID: 167

    "Double shot buddy"

    Quality: 1

    A familiar which follows Isaac and shoots two normal tears at once in a V-shaped pattern

    Each of Harlequin Baby's tears deal 4 damage

    Harlequin Baby fires tears at a rate of 1 tear per second

    Counts as 1 of 3 familiar items needed towards the Conjoined transformation

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, bug, eyes, pink, red

  • Epic Fetus

    ItemID: 168

    "On-demand air strike"

    Quality: 4

    Tears now become missiles which deal huge damage to anything nearby

    Missiles damage = damage * 20

    This item places a controllable red target on the ground which will cause a missile to fall from the sky and hit it after a short period of time

    UNLOCK: Unlock this item by beating Challenge #19 (The Family Man)

      Type: Passive, Tear Modifier

      Item Pool: Secret Room

    * item room, treasure room, item room pool, fetus in a jar, bug, white, hat, pink

  • Polyphemus

    ItemID: 169

    "Mega tears"

    Quality: 4

    High Damage Up - (damage + 4) * 2

    Tears Down significantly (Tear delay * 2.1 + 3)

    If a tear kills an enemy, it continues to travel forward with the leftover damage

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, large eye, cyclops, one eye, blue, white

  • Daddy Longlegs

    ItemID: 170

    "Daddy's love"

    Quality: 3

    A shadow follows Isaac and stomps on enemies randomly, dealing 40 damage per stomp (2 damage ticks at 20 damage each)

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, white, yarn, wool, spider

  • Spider Butt

    ItemID: 171

    "Mass enemy slowdown + damage"

    Quality: 1

    Upon use, does 10 damage to all enemies in the room and gives them a slowing effect for 4 seconds

    Counts as 1 of 3 spider items needed towards the Spider Baby transformation

    REPENTANCE - Enemies killed by Spider Butt will now spawn friendly blue spiders

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, brown, red, web

  • Sacrificial Dagger

    ItemID: 172

    "My fate protects me"

    Quality: 3

    Gives Isaac an orbital knife that blocks shots and deals 15 damage per tick on contact with enemies

    The highest damage orbital in the game, dealing 225 damage per second

    Synergises very well with invulnerability items such as Book of Shadows

    UNLOCK: Unlock this item by beating the Chest with Eve

      Type: Passive, Orbital

      Item Pool: Item Room, Devil Room

    * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, bloody, knife, red, silver

  • Mitre

    ItemID: 173

    "You feel blessed"

    Quality: 3

    Gives a 33% chance of converting red heart drops into soul hearts

    Counts as 1 of 3 angel items needed towards the Seraphim transformation

    REPENTANCE - Mitre now only has a 33% chance to convert red heart drops into soul hearts (down from 50%).

      Type: Passive

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, the lost item pool, gold, orange, yellow, cross, pope, hat

  • Rainbow Baby

    ItemID: 174

    "Random buddy"

    Quality: 1

    A familiar the follows Isaac and fires random tears

    Rainbow Baby's tears can choose from any of the other familiars, such as homing, spectral, tar shots etc

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, purple

  • Dad's Key

    ItemID: 175

    "Opens all doors..."

    Quality: 1

    Upon use, opens all closed doors in the current room, including the ones which require a key to enter and secret room doors

    Can be used to open the golden door that appears in the Dark Room or the Chest

    Cannot be used to escape the Mom's Foot boss, open angel/devil rooms, or open the door to the Blue Womb floor

    UNLOCK: Unlock this item by collecting both Key Pieces #1 & #2 for the first time

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room, Key Beggar

    * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, brown, brass, copper, dads key, dad key

  • Stem Cells

    ItemID: 176

    "HP up"

    Quality: 1

    +1 HP Up

    +0.16 Shot Speed Up

    Heals one red heart container when picked up

    REPENTANCE - Stem Cell now heals Isaac's red heart containers to 50% each floor. If Isaac already has 50% health or more, it does the previous effect of healing half of a heart

      Type: Passive

      Item Pool: Item Room, Boss Room

    * boss room pool, boss room item, item room, treasure room, item room pool, lumpy, red, balls

  • Portable Slot

    ItemID: 177

    "Gamble 24/7"

    Quality: 0

    Using the portable slot takes a coin and has a chance to give a pickup - similar to how the normal slot machines work

    REPENTANCE - The delay between uses was removed, allowing you to spam-use it

      Type: Active

      Recharge Time: Instant

      Item Pool: Shop, Beggar

    * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool,red, robot, head, cube

  • Holy Water

    ItemID: 178

    "Splash!"

    Quality: 0

    REPENTANCE - This item has been reworked. While firing tears the water will be fired as a projectile across the room. If it touches an enemy it breaks and leave a pool on the floor which freezes enemies and deals 8 damage per tick

      Type: Passive, Familiar

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, the lost item pool, white, blue, cross, jar

  • Fate

    ItemID: 179

    "Flight eternal"

    Quality: 3

    Gives Isaac an eternal heart and the ability to fly

    Taking an eternal heart to the next floor or collecting two on the same floor gives you an extra heart container

    UNLOCK: Unlock this item by beating the Chest with Blue Baby

      Type: Passive

      Item Pool:

    * golden chest pool, gold chest pool, blue head, the lost item pool, dead, ball

  • The Black Bean

    ItemID: 180

    "Toot on touch"

    Quality: 0

    Upon taking damage, Isaac will fart, causing all enemies in close proximity to become poisoned

    Black Bean deals your tear damage for 6 ticks

      Type: Passive

      Item Pool: Item Room, Beggar

    * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, treasure room, item room pool, the lost item pool, kidney, grey, gray

  • White Pony

    ItemID: 181

    "Flight + holy death"

    Quality: 2

    Allows Isaac to fly while the White Pony is held

    While held, sets your speed stat to 1.5 if it isn't already that high. If your speed stat is already higher then that value is still used

    Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies while also casting the effect of Crack The Sky

    Drops from the Conquest boss fight

    REPENTANCE - White Pony's charge time has been reduced to 2 (from 6). The beams of light now trail behind Isaac when charging with it (damage formula of the beams is damage * 4 + 10).

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: None (Conquest boss only)

    *, red, horse, head

  • Sacred Heart

    ItemID: 182

    "Homing shots + DMG up"

    Quality: 4

    Tears are now white, do a lot more damage and move slower across the screen with a homing effect

    Health Up

    Damage Up (damage * 2.3 + 1)

    -0.4 Tears Down

    -0.25 Shot Speed Down

    +4.125 Range Up

    +0.75 Tear Height

    Full red heart heal

    REPENTANCE - Homing tears now target enemies much more reliably

      Type: Passive, Tear Modifier

      Item Pool: Angel Room

    * angel room pool, god room pool, angel room item, red, fire, flame, orange, cross

  • Toothpicks

    ItemID: 183

    "Tears + shot speed up"

    Quality: 3

    +0.7 Tears Up

    +0.16 Shot Speed Up

    Does not increase your damage, simply makes your tears red

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, sticks, brown, yellow

  • Holy Grail

    ItemID: 184

    "Flight + HP up"

    Quality: 3

    +1 HP Up

    Gives Isaac the ability to fly

    Heals one red heart container when picked up

    Counts as 1 of 3 angel items needed towards the Seraphim transformation

      Type: Passive

      Item Pool: Angel Room

    * angel room pool, god room pool, angel room item, the lost item pool, cup, wooden, gold, chalice, indiana jones

  • Dead Dove

    ItemID: 185

    "Flight + spectral tears"

    Quality: 3

    Gives Isaac the ability to fly and spectral tears

    An item only found in the Angel room

    Counts as 1 of 3 angel items needed towards the Seraphim transformation

      Type: Passive

      Item Pool: Angel Room

    * angel room pool, god room pool, angel room item, bird, white

  • Blood Rights

    ItemID: 186

    "Mass enemy damage at a cost"

    Quality: 0

    Upon use, takes away one full heart and deals 40 damage to the entire room

    With the Isaac's Heart item, you can use Blood Rights without taking damage

    UNLOCK: Unlock this item by beating Satan with Samson

      Type: Active

      Recharge Time: Instant

      Item Pool: Item Room

    * item room, treasure room, item room pool, razor, straight, edge, barber, bloody, brown, silver

  • Guppy's Hairball

    ItemID: 187

    "Swing it"

    Quality: 1

    Follows behind Isaac and can be swung back and forth, dealing 5 contact damage per tick to anything it hits

    Every time the hairball kills an enemy, it grows in size allowing it to deal more damage

    This is one of the items which allows you to transform into Guppy

    Moving to a new floor decreases the size of the hairball

    Counts as 1 of 3 cat items needed towards the Guppy transformation

      Type: Passive, Familiar

      Item Pool: Devil Room

    * devil pool, devil room pool, devil deal, grey, brown, pile, guppys hairball, guppy hairball

  • Abel

    ItemID: 188

    "Mirrored buddy"

    Quality: 0

    A familiar that mirrors the player's movements and shoots tears directly at Isaac

    Abel's tears do 3.5 damage, unless playing as Cain in which case they do 5

    REPENTANCE - Abel now has an increased rate of fire, and will mirror to the other side of the room, even if it's off screen. If picked up by Cain, it shoots blood tears and the damage becomes increased to 5 (instead of the usual 3.5)

    UNLOCK: Unlock this item by beating the Dark Room with Cain

      Type: Passive, Familiar

      Item Pool: Item Room

    * golden chest pool, gold chest pool, item room, treasure room, item room pool, follower, everyone knows it's abel, brown, grey, gray, dead, head, grey, green cain and abel cain & abel

  • SMB Super Fan

    ItemID: 189

    "All stats up"

    Quality: 3

    Isaac turns red like Meatboy

    +1 HP Up

    +0.3 Damage Up

    +0.2 Tears Up

    +0.5 Range Up

    +0.2 Speed Up

    +1.0 Tear Height

    Full red heart heal

    UNLOCK: Unlock this item by beating Challenge #14 (It's in the Cards)

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, bloody, silver, grey, gray, sharp

  • Pyro

    ItemID: 190

    "99 bombs"

    Quality: 3

    Gives Isaac 99 bombs

      Type: Passive

      Item Pool: Item Room, Secret Room, Bomb Beggar

    * secret room pool, item room, treasure room, item room pool, smile, face, grinning, doitfgt

  • 3 Dollar Bill

    ItemID: 191

    "Rainbow tears"

    Quality: 2

    Grants Isaac random tear effects

    The tear type changes every few seconds

    REPENTANCE - The list of possible tear effects was updated in Repentance, to include all missing and new ones

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, pink note, money, cash, three dollar bill, cash money

  • Telepathy for Dummies

    ItemID: 192

    "Temporary psychic shot"

    Quality: 0

    When used, Isaac gains homing shots for the current room

    Counts as 1 of 3 book items needed towards the Bookworm transormation

    REPENTANCE - Homing tears now target enemies much more reliably and gives a +3.0 Range Up on use

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room, Library

    * library pool, library room, book room pool, item room, treasure room, item room pool, yellow book how to

  • MEAT!

    ItemID: 193

    "DMG + HP up"

    Quality: 2

    +1 HP Up

    +0.3 Damage Up

    Heals one red heart container when picked up

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, bone, red, brown

  • Magic 8 Ball

    ItemID: 194

    "Shot speed up"

    Quality: 1

    +0.16 Shot Speed Up

    Gives Isaac a random tarot card when picked up

    +15% chance for Planetariums to spawn

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    * boss room pool, boss room item, eight, grey, gray

  • Mom's Coin Purse

    ItemID: 195

    "What's all this...?"

    Quality: 1

    Drops 4 random pills on the floor around Isaac

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Passive

      Item Pool: Shop, Boss Room, Challenge Room, Beggar, Demon Beggar

    * dungeon room, blood challenge room, arena pool, demon beggar pool, demon judgement pool, devil beggar pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, shop room pool, shop item pool, bag, pouch, moms coin purse, mom coin purse

  • Squeezy

    ItemID: 196

    "Tears up"

    Quality: 3

    +2 Soul Hearts

    +0.4 Tears Up

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    * boss room pool, boss room item, mr. squeezy, mr squeezy, cobaltstreak, white, brown, red, bow,

  • Jesus Juice

    ItemID: 197

    "Damage + range up"

    Quality: 2

    +0.5 Damage Up

    +0.25 Range Up

    +0.5 Tear Height

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, purple, carton, grape drank

  • Box

    ItemID: 198

    "Stuff"

    Quality: 1

    When picked up, spawns 1 red heart, 1 key, 1 bomb, 1 coin, 1 card/rune, 1 pill and 1 trinket

      Type: Passive

      Item Pool: Boss Room, Challenge Room

    * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, brown, orange, cardboard

  • Mom's Key

    ItemID: 199

    "Better chest loot +2 keys"

    Quality: 3

    +2 Keys

    Doubles the yield of hearts, coins, bombs and keys that spawn from non-red chests

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Passive

      Item Pool: Shop, Challenge Room, Key Beggar

    * key master pool, key beggar pool, key judgement pool, , dungeon room, blood challenge room, arena pool, shop room pool, shop item pool, golden, horns, moms key, mom key

  • Mom's Eyeshadow

    ItemID: 200

    "Charm tears"

    Quality: 1

    Tears have a random chance to charm enemies

    Charmed enemies will prioritize attacking other enemies in the room, otherwise they will still attack Isaac

    The chance to charm enemies is affected by your luck stat and at +27 Luck it will activate every time

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Passive

      Item Pool: Item Room, Challenge Room

    * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, grey, gray, blue, moms eyeshadow

  • Iron Bar

    ItemID: 201

    "Concussive tears"

    Quality: 3

    +0.3 Damage Up

    Tears now have a chance to concuss enemies, causing them to walk around dazed and confused for a short period of time

    The chance to concuss enemies is affected by your luck stat and at +27 Luck it will activate every time

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, grey, gray, silver, ingot

  • Midas Touch

    ItemID: 202

    "Golden touch"

    Quality: 2

    Isaac's touch now petrifies enemies, turning them to gold for a few seconds.

    If an enemy is killed while it is golden, it will drop between 1-4 coins

    Contact damage is also dealt to enemies equal to the amount of coins Isaac is currently holding

    Has a synergy with The Poop item, which gives it a high chance to spawn golden poops

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, gold, ingot, bar, orange

  • Humbleing Bundle

    ItemID: 203

    "1+1free 4evar!"

    Quality: 3

    All future pennies, keys, bombs and hearts have a chance to drop in pairs

    Does not work for other pickups, such as soul hearts, nickels, dimes, cards, pills etc

    REPENTANCE - No longer guarantees all pickups to be doubled (is now chance-based), and doesn't change existing pickups that already dropped

      Type: Passive

      Item Pool: Shop

    * Humbling bundle shop room pool, shop item pool, paper, purple, brown

  • Fanny pack

    ItemID: 204

    "Filled with goodies"

    Quality: 1

    When you take damage, there is a 50% chance to drop a random heart, key, bomb or coin

      Type: Passive

      Item Pool: Shop, Beggar

    * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, bag, satchel, backpack, purse, satchel, brown

  • Sharp plug

    ItemID: 205

    "Charge with blood"

    Quality: 1

    When your spacebar item is not fully charged, you can press spacebar to recharge it at the cost half of a heart per charge

    Can be used on partially charged items

    Will not kill you if used - it stops a half a heart left

    Red hearts are taken before other kinds

    The Sharp Plug will take health from Soul/Black hearts (if any) before taking red hearts

    REPENTANCE - This item has been reworked, see above. No longer ruins your devil/angel chance if used on red hearts

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, the lost item pool, white,

  • The Guillotine

    ItemID: 206

    "An out-of-body experience"

    Quality: 3

    +1.0 Damage Up

    -1 Tear Delay (Tears Up)

    Causes Isaac's head to detach and orbit his body, blocking shots and dealing 7 contact damage per tick

    BFFs will cause the Guillotine head to do double damage (14 damage per tick)

    Tears are still fired from Isaac's head but the hitbox remains around his body

    UNLOCK: Unlock this item by beating the Isaac boss with Judas

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, chop, head, silver, metal

  • Ball of Bandages

    ItemID: 207

    "Gotta lick em all"

    Quality: 2

    Gives Isaac an orbital ball of bandages that deals 7 contact damage per tick and blocks enemy shots

    Collecting a second Ball of Bandages in the run turns the orbital into a pink head that shoots tears that deal 7 damage each and have a chance to charm enemies

    Getting a third Ball of Bandages will transform the head into bandage girl which will chase enemies dealing 3.5 contact damage per tick while firing charm tears

    A fourth Ball of Bandages will make the Bandage Girl bigger and stronger, making her deal 5.5 damage per tick instead

    Any further Ball of Bandages will repeat the cycle

    Charmed enemies will prioritize attacking other enemies in the room, otherwise they will still attack Isaac

      Type: Passive, Orbital

      Item Pool: None (Horsemen boss only)

    * super meat boy, pink, plasters

  • Champion Belt

    ItemID: 208

    "DMG + Challenge up"

    Quality: 3

    +1.0 Damage Up

    Increases the chance of champion enemies appearing by 15%

    Doesn't affect the chance for champion bosses to spawn

    An item only found in the Shop room pool

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, red, croissant, crescent

  • Butt Bombs

    ItemID: 209

    "Toxic blast +5 bombs"

    Quality: 2

    +5 bombs

    Bombs now become poop bombs, which deal 10 damage to all enemies in the room and daze them for a short period of time

    Butt Bombs heal the poop bosses (Dingle, Dangle, Brownie) by 25% of their max HP

      Type: Passive

      Item Pool: Item Room, Bomb Beggar

    * boss rush pool, boss rush room, item room, treasure room, item room pool, poop, face, brown

  • Gnawed Leaf

    ItemID: 210

    "Unbreakable"

    Quality: 1

    If Isaac stands still and stops shooting for a second, he turns to stone, making him invincible until he moves/shoots again

    Using bombs or your active item will remove the invicibility as well

    This item is a reference to the Tanuki suit in Super Mario 3

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, raccoon, green

  • Spiderbaby

    ItemID: 211

    "Spider revenge"

    Quality: 1

    Spawns 2-5 friendly attack spiders every time you take damage

    Counts as 1 of 3 spider items needed towards the Spider Baby transformation

    REPENTANCE - Buffed, used to spawn 1-2 spiders

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, the lost item pool, purple, blue, heart, cute spider baby

  • Guppy's Collar

    ItemID: 212

    "Eternal life?"

    Quality: 2

    When Isaac dies, he has a 50% chance to resurrect with 1/2 a heart

    Counts as 1 of 3 cat items needed towards the Guppy transformation

      Type: Passive

      Item Pool: Devil Room, Curse Room, Red Chest

    * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, purple, pink, circle, guppys collar

  • Lost Contact

    ItemID: 213

    "Shielded tears"

    Quality: 2

    All of Isaac's tears now have a shield, allowing them to block an enemy projectile

    If a tear blocks something, both Isaac's and the enemies tears are destroyed

    -0.16 Shot Speed Down

      Type: Passive

      Item Pool: Item Room, Secret Room

    * secret room pool, item room, treasure room, item room pool, white, lump, oval

  • Anemic

    ItemID: 214

    "Toxic blood"

    Quality: 0

    +5 Range Up

    When Isaac takes damage, he will start to leave a trail of blood creep behind him as he walks for the current room. The creep deals 2 damage per tick while enemies stand in it

    Lazarus' revived form (Lazarus II) respawns with this item

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, blood drop, red blood, drip

  • Goat Head

    ItemID: 215

    "He accepts your offering"

    Quality: 3

    Gives Isaac a guaranteed devil or angel room on every floor that they can appear, even if you have already beaten the boss and it didn't show up originally

    Taking the Goat Head (or any other item) in a Devil Deal bars you from encountering Angel Rooms naturally. After which, the only way to access an Angel Room is via the Sacrifice Room

      Type: Passive

      Item Pool: Devil Room, Curse Room

    * curse room pool, red chest pool, red chest item pool, golden chest pool, gold chest pool, devil pool, devil room pool, devil deal, brown, horns

  • Ceremonial Robes

    ItemID: 216

    "Sin up"

    Quality: 3

    +3 Black Hearts

    +1 Damage Up

    When depleted, Black Hearts deal 40 damage to the entire room, in a Necronomicon style effect

      Type: Passive

      Item Pool: Devil Room, Curse Room, Demon Beggar

    * curse room pool, demon beggar pool, demon judgement pool, devil beggar pool, devil pool, devil room pool, devil deal, grey, gray, hood

  • Mom's Wig

    ItemID: 217

    "You feel itchy"

    Quality: 3

    Isaac now has a small chance to create friendly attack spiders everytime he fires a tear

    Can create up to a maximum of 5 spiders in the room at one time

    The Hive Mind item allows Mom's Wig to spawn a maximum of 10 spiders at once, and increases their damage

    The chance to create a spider is affected by your luck stat and at +10 Luck it will activate every time

    Heals you for 1 red heart when picked up

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Passive

      Item Pool: Item Room, Challenge Room

    * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, orange, moms wig

  • Placenta

    ItemID: 218

    "HP up + regen"

    Quality: 2

    +1 HP Up

    Gives a chance to heal 1/2 a red heart every 60 seconds

    Heals one red heart container when picked up

    There are no restrictions on when the regeneration effect happens as long as the game is not paused, so you can simply afk and heal over time

    Works in crawl spaces

    It's possible to find this item by blowing up Polyps (the weird red rocks found in the Womb floors)

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, the lost item pool, purple, red, lump

  • Old Bandage

    ItemID: 219

    "HP up"

    Quality: 2

    +1 HP Up

    The given heart container is empty

    When you get hit, you will sometimes cause hearts to drop on the floor

    The chance to drop hearts is affected by your luck stat and at +29 Luck it will activate 50% of the time

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, the lost item pool, plasters, white

  • Sad Bombs

    ItemID: 220

    "Tear blast +5 bombs"

    Quality: 3

    +5 Bombs

    Everytime a bomb explodes, it will release a circle of 10 tears outwards, much like the Tammy's Head effect

    The tears from each bomb deal a flat 25 damage and are affected by any tear modifiers Isaac has

    The tears caused by Sad Bombs are much larger and do a lot more damage than Isaac's normal tears

      Type: Passive

      Item Pool: Item Room, Bomb Beggar

    * boss rush pool, boss rush room, item room, treasure room, item room pool, crying, face

  • Rubber Cement

    ItemID: 221

    "Bouncing tears"

    Quality: 3

    Isaac's tears now bounce off walls and objects in the environment, such as rocks and pots

    Allows tears to hit the same enemy multiple times

    If you also have Lost Contact, tears will bounce off enemy projectiles instead of being destroyed

    UNLOCK: Unlock this item by beating Mom's heart 2 times

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    * item room, treasure room, item room pool, orange, brown, bottle, jar

  • Anti-Gravity

    ItemID: 222

    "Antigravity tears + tears up"

    Quality: 3

    -2 Tear Delay (Tears Up)

    As you hold down the fire button, shots will float in the same place until you release the fire key again

    Allows you to store up a lot of tears in the air and release them all at once

    When the tears are released, they will fire off in the direction that Isaac was originally facing when it was created

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * anti gravity, item room, treasure room, item room pool, anti gravity, atom, nucleus

  • Pyromaniac

    ItemID: 223

    "Hurts so good +5 bombs"

    Quality: 4

    +5 Bombs

    All explosions now heal Isaac for 0.5 red hearts instead of hurting him

    REPENTANCE - Pyromaniac now grants Isaac immunity to fire, but no longer protects against stomps or shockwaves. Explosions now only heal Isaac for half of a heart (previously healed a full heart)

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, fire, heart, orange, burning, stannis

  • Cricket's Body

    ItemID: 224

    "Splash damage + tears up"

    Quality: 3

    -1 Tear Delay (Tears Up)

    -10.0 Range Down

    x1.2 Tear Size

    Makes tears break into 4 smaller tears on impact with anything, which deal half of your damage

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, brown, orange, headless, crickets body

  • Gimpy

    ItemID: 225

    "Sweet suffering"

    Quality: 2

    When getting hit, this item has a chance to drop a soul heart or black heart

    The chance to spawn a heart is affected by your luck stat and at +22 Luck it will activate 50% of the time

    Enemies have a chance to drop half a red heart when killed

      Type: Passive

      Item Pool: Item Room, Devil Room, Curse Room, Demon Beggar

    * curse room pool, demon beggar pool, demon judgement pool, devil beggar pool devil pool, devil room pool, devil deal, item room, treasure room, item room pool, gimp mask, the lost item pool, grey, gray, black

  • Black Lotus

    ItemID: 226

    "HP up x3"

    Quality: 2

    +1 HP Up

    +1 Soul Heart

    +1 Black Heart

    Heals one red heart container when picked up

    When depleted, Black Hearts deal 40 damage to the entire room, in a Necronomicon style effect

    An item only found in the secret room pool

      Type: Passive

      Item Pool: Secret Room

    * secret room pool, , the lost item pool, purple, black, grey, gray, flower, mtg magic the gathering, vintage

  • Piggy Bank

    ItemID: 227

    "My life savings"

    Quality: 1

    +3 Coins when picked up

    When you take damage, 1-2 coins will drop on the floor

    When playing as the Keeper, this item drops 0-1 coins instead

      Type: Passive

      Item Pool: Item Room, Shop

    * shop room pool, shop item pool, item room, treasure room, item room pool, pink, oink

  • Mom's Perfume

    ItemID: 228

    "Fear shot"

    Quality: 2

    -1 Tear Delay (Tears Up)

    Isaac's tears have a 15% chance of causing a fear effect

    Feared enemies will run away from Isaac temporarily

    The chance to fear enemies is affected by your luck stat and at +85 Luck it will activate every time

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Passive

      Item Pool: Item Room, Challenge Room

    * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, spray, brown, white, yellow, moms purfume

  • Monstro's Lung

    ItemID: 229

    "Charged attack"

    Quality: 2

    Tears can now be charged and released in a shotgun style effect, much like Monstro's main attack

    Tears down (Tear delay * 4.3)

    Partial charging does nothing - must be fully charged to use

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, pink, body part, monstros lung

  • Abaddon

    ItemID: 230

    "Evil up + DMG up + fear shot"

    Quality: 4

    On pickup Abaddon converts all your heart containers to black hearts, then gives you +2 more black hearts

    +1.5 Damage Up

    +0.2 Speed Up

    Tears now have a chance to induce the fear effect, causing enemies to run away from Isaac for a short period

    The chance to fear enemies is affected by your luck stat and at +85 Luck it will activate every time

    When depleted, Black Hearts deal 40 damage to the entire room, in a Necronomicon style effect

    Counts as 1 of 3 evil items needed towards the Leviathan transformation

    REPENTANCE - No longer kills Keeper when picked up, just reduces coin health to 1

    UNLOCK: Unlock this item by beating the Chest with Azazel

      Type: Passive

      Item Pool: Devil Room, Demon Beggar

    * devil pool, devil room pool, devil deal, red devil sign, abandon, abadon, pentagram

  • Ball of Tar

    ItemID: 231

    "Sticky feet..."

    Quality: 2

    Isaac leaves a trail of tar behind him which will slow down enemies that walk over it

    Tears have a chance to slow enemies and their projectiles for a short period of time

    The chance to slow enemies can improve based on your luck stat and will always slow enemies at +18 Luck

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, black, grey, gray

  • Stop Watch

    ItemID: 232

    "Let's slow this down a bit"

    Quality: 4

    +0.3 Speed Up

    The Stop Watch applies a permanent but slight slowing effect to all enemies and their projectiles

    The slowing effect has a reduced effect against Brimstone lasers fired by enemies

    REPENTANCE - Stop Watch now slows down all enemies in the game once again, but the slow effect is much less drastic. No longer has an "on hit" effect

    UNLOCK: Unlock this item by donating 999 pennies to the Shop

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, stopwatch, blue, pocket, clock

  • Tiny Planet

    ItemID: 233

    "Orbiting tears + range up"

    Quality: 0

    +7.0 Tear Height

    Range greatly increased

    Tears now revolve around Isaac's Body at a fixed distance until they hit the ground

    Aiming in the opposite direction is often better due to how the tears circle around Isaac

    Causes a lot of great synergies with items such as Lump of Coal, Brimstone, Rubber Cement, Technology and most of the worm trinkets

    REPENTANCE - Tiny Planet's orbit now more tightly follows Isaac. To help with range, the orbit is now also offset based on the current direction Isaac is shooting

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, grey, gray, asteroid, silver, ball

  • Infestation 2

    ItemID: 234

    "Infestation shot"

    Quality: 4

    Creates a friendly blue spider when you kill an enemy

    Spiders are spawned at the location where the enemy died

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, pink, smile

  • E. Coli

    ItemID: 236

    "Turdy Touch"

    Quality: 1

    E. Coli turns normal enemies into poop if they touch you

    Enemies can turn into poop even if they do not do contact damage, allowing you to apply the effect without taking damage

    Can be combined with Midas Touch to turn enemies into Golden Poop

    This does not work on mini-bosses and bosses

    Counts as 1 of 3 poop items needed towards the Oh Crap transformation

      Type: Passive

      Item Pool: Item Room

    * e coli, item room, treasure room, item room pool, tampon, bloody, red, white

  • Death's Touch

    ItemID: 237

    "Penetrative shots + DMG up"

    Quality: 3

    +1.5 Damage Up

    -0.3 Tears Down

    x2 Tear Size

    Isaac's tears turn into large scythes that pierce through enemies (Similar to how Death's scythes look)

    UNLOCK: Unlock this item by beating Challenge #17 (Waka Waka)

      Type: Passive, Tear Modifier

      Item Pool: Item Room, Devil Room

    * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, axe, silver, grey, gray, deaths touch, death touch

  • Key Piece #1

    ItemID: 238

    "???"

    Quality: 0

    Increases your chances to find an Angel Room instead of a Devil Room. See the dedicated Devil room page for more details

    First half of the key required to enter the door to the Mega Satan boss

    Drops from one of the angels which appear by bombing the statue in an angel room

      Type: Passive, Familiar

      Item Pool: None (Angel statue only)

    * angel room, angels, broken, yellow, gold, circle

  • Key Piece #2

    ItemID: 239

    "???"

    Quality: 0

    Increases your chances to find an Angel Room instead of a Devil Room. See the dedicated Devil room page for more details

    Second half of the key required to enter the door to the Mega Satan boss

    Drops from one of the angels which appear by bombing the statue in an angel room

      Type: Passive, Familiar

      Item Pool: None (Angel statue only)

    *, yellow, gold, broken

  • Experimental Treatment

    ItemID: 240

    "Some stats up, some stats down"

    Quality: 1

    Randomly increases 4 of your stats, and decreases 2 of them

    Possible stat changes are fixed values: ±1 health, ±1 damage, ±0.2 speed, ±0.5 range, ±0.5 tears, ±0.2 shot speed, ±1 luck

    Counts as 1 of 3 syringe items needed towards the Spun transformation

    UNLOCK: Unlock this item by beating Mom's Heart 7 times

      Type: Passive

      Item Pool: Item Room, Boss Room, Demon Beggar

    * demon beggar pool, demon judgement pool, devil beggar pool, boss room pool, boss room item, item room, treasure room, item room pool, yellow syringe, needle, injection

  • Contract From Below

    ItemID: 241

    "Wealth, but at what cost?"

    Quality: 3

    Doubles pickups and chests from clearing a room

    Also gives a 30% chance for room clear rewards to not spawn

    Doesn't affect coins spawned in Greed Mode

      Type: Passive

      Item Pool: Devil Room, Curse Room, Demon Beggar

    * curse room pool, demon beggar pool, demon judgement pool, devil beggar pool, devil pool, devil room pool, devil deal, paper, pink, brown, isaac

  • Infamy

    ItemID: 242

    "Damage reduction"

    Quality: 2

    Gives a 50% chance to not take damage from projectiles

      Type: Passive

      Item Pool: Item Room, Secret Room

    * golden chest pool, gold chest pool, secret room pool, item room, treasure room, item room pool, purple, pink, mask, face

  • Trinity Shield

    ItemID: 243

    "You feel guarded"

    Quality: 3

    Puts a shield in front of Isaac which blocks projectiles

    The shield will rotate based on the direction in which Isaac is firing tears

      Type: Passive

      Item Pool: Angel Room

    * angel room pool, god room pool, angel room item, blue, silver, metal

  • Tech.5

    ItemID: 244

    "It's still being tested"

    Quality: 3

    Gives Isaac a laser that will fire at random intervals in addition to your normal tears

    Each laser does damage equal to your current tear damage

    The laser will occasionally fire with one of these effects: Hook Worm, Spoon Bender, Tiny Planet, Mysterious Liquid, Rubber Cement

    Luck has no effect on the rate at which Tech.5 fires and does not scale with items that increase your tears stat

    UNLOCK: Unlock this item by beating Challenge #18 (The Host)

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * technology.5, tech 5, item room, treasure room, item room pool, white, red, eye, robot

  • 20/20

    ItemID: 245

    "Double shot"

    Quality: 4

    Isaac now shoots two tears at once

    Unlike the Inner Eye and Mutant Spider items, this double shot item does not give a tears down

    REPENTANCE - Reduces damage done by 25%; hitting both tears is still effectively a 1.5x damage boost

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * 20 20, 2020, item room, treasure room, item room pool, black glasses, spectacles

  • Blue Map

    ItemID: 246

    "Secrets"

    Quality: 2

    Reveals the locations of the secret and super secret room for the current floor and all future floors

    UNLOCK: Unlock this item by donating 10 pennies to the Shop

      Type: Passive

      Item Pool: Shop, Beggar, Key Beggar

    * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, x, paper

  • BFFS!

    ItemID: 247

    "Your friends rule!"

    Quality: 2

    Makes all of Isaac's familiars stronger and bigger

    Causes most familiars to deal double damage

    Has no effect on most familiars that scale with Isaac's tear damage

      Type: Passive

      Item Pool: Shop, Key Beggar

    * key master pool, key beggar pool, key judgement pool, shop room pool, shop item pool, red, heart, arrow

  • Hive Mind

    ItemID: 248

    "Giant spiders and flies"

    Quality: 2

    Causes your friendly blue spiders and flies to become bigger and do x2 more damage

    Allows Mom's Wig to spawn a maximum of 10 spiders at once instead of 5

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, blue, fat

  • There's Options

    ItemID: 249

    "More options"

    Quality: 3

    Two items now spawn after beating a boss fight and the boss rush, however only one can be taken

    The additional item will pick from the Boss Item Pool

    Does nothing after the Krampus fight

    Unlocked by donating to the donation machine in the shop

    UNLOCK: Unlock this item by donating 50 pennies to the Shop

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, white, question mark, square, theres options

  • Bogo Bombs

    ItemID: 250

    "1+1 bombs"

    Quality: 1

    All bomb pickups are now 1+1 bombs

    An item only found in the Shop item pool

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, purple, paper, ticket

  • Starter Deck

    ItemID: 251

    "Extra card room"

    Quality: 2

    Spawns a random card

    Isaac can now hold 2 cards or runes at once. Tap the drop button to cycle between each one

    All future pill drops will now instead become cards

    An item only available in the Shop room

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, packet, deck, brown, orange

  • Little Baggy

    ItemID: 252

    "Extra pill room"

    Quality: 1

    Allows for 2 pills to be held. Tap the drop button to cycle between each one

    Drops a pill on the floor when picked up

    Changes all card and rune drops into pills. Any Tarot card or rune on the floor or current held when picking this item up will change into a pill

    Dice Shard counts as a card and will be converted

    UNLOCK: Unlock this item by picking up 2 of the following items: Roid Rage, The Virus, Growth Hormones, Experimental Treatment or Speed Ball

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, brown, purple

  • Magic Scab

    ItemID: 253

    "HP + luck up"

    Quality: 2

    +1 HP Up

    +1.0 Luck Up

    Heals one red heart container when picked up

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, red, wedge, purple, triangle

  • Blood Clot

    ItemID: 254

    "DMG + range up"

    Quality: 2

    +1.0 Damage Up (Left eye only)

    +5 Range Up (Left eye only)

    The above stats only apply to tears fired from Isaac's left eye or with a 50% chance if you have an item which causes you to fire from a single source only

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, red, blob, circle, spot

  • Screw

    ItemID: 255

    "Tears + shot speed up"

    Quality: 3

    +0.5 Tears Up

    +0.2 Shot Speed Up

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    * boss room pool, boss room item, grey, gray

  • Hot Bombs

    ItemID: 256

    "Burning blast +5 bombs"

    Quality: 1

    +5 Bombs

    Grants immunity to fire

    Enemies touching placed bombs take 16 damage

    Gives all bombs a burning effect when they explode, leaving fire on the floor which deals 22 damage to enemies

    REPENTANCE - Hot Bombs now have greatly increased contact damage (increased from 1 to 16), and passively grants Isaac immunity to fire

      Type: Passive

      Item Pool: Item Room, Bomb Beggar

    * item room, treasure room, item room pool, fire, orange, flame, face

  • Fire Mind

    ItemID: 257

    "Flaming tears"

    Quality: 2

    Isaac's tears now set enemies on fire, leaving a damage over time effect that does 4 or 6 damage per tick

    There is a chance that tears that hit enemies will explode, leaving a small fire on the floor that damages enemies

    Exploding tears deal damage * 2 + 22 per tick

    The chance for tears to explode is affected by your luck stat and at +13 Luck it will activate every time

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, fire, flame, orange, back, ball, burning

  • Missing No

    ItemID: 258

    "Syntax error"

    Quality: 2

    When picked up, and at the start of each floor this rerolls all your current items, giving you a new item to replace each of the ones you had

    Also rerolls all your stats at the same time, giving a random flat modifier that changes each time

    Doesn't affect important items such as Polaroid, Negative and Key Pieces

    UNLOCK: Unlock this item by beating Boss Rush with Lazarus

      Type: Passive

      Item Pool: Secret Room

    * secret room pool, mondrian, painting, yellow, blue, red, white

  • Dark Matter

    ItemID: 259

    "Fear shot"

    Quality: 3

    +1.0 Damage Up

    Tears now have a chance to apply the fear effect to enemies, which causes them to run away from Isaac

    The chance to fear enemies is affected by your luck stat and at +20 Luck it will activate every time

    An item only found in the devil room pool (Note: The Fallen boss pulls items from the Devil Room Pool)

      Type: Passive

      Item Pool: Devil Room, Demon Beggar

    * devil pool, devil room pool, devil deal, grey, gray, fist, glow

  • Black Candle

    ItemID: 260

    "Curse of immunity + evil up"

    Quality: 3

    +1 Black Heart

    Immunity to all floor curses (e.g. Curse of the Lost)

    Black Candle removes the teleportation effect of Cursed Eye

    +15% chance of a devil or angel room opening after the boss fight

    UNLOCK: Unlock this item by donating 150 pennies to the Shop

      Type: Passive

      Item Pool: Shop, Curse Room

    * curse room pool, shop room pool, shop item pool, grey, gray

  • Proptosis

    ItemID: 261

    "Short range mega tears"

    Quality: 4

    Gives Isaac high damage tears with a short range

    Tear size and damage falls off very fast with this item, the further the tear travels the less damage it does

    Tear damage starts at triple (300%) and decreases over range to eventually be 0%

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, red, bloody, eyeball

  • Missing Page 2

    ItemID: 262

    "Evil up + your enemies will pay"

    Quality: 0

    +1 Black Heart

    If the total sum of all your health is at one heart after taking damage, the necronomicon effect will activate, dealing 40 damage to the entire room

    REPENTANCE - Missing Page 2 now doubles all black heart and Necronomicon damage (to 80 instead of the usual 40)

      Type: Passive

      Item Pool: Devil Room, Demon Beggar, Secret Room

    * demon beggar pool, demon judgement pool, devil beggar pool, secret room pool, devil pool, devil room pool, devil deal, the lost item pool, red, bloody, purple, paper

  • Smart Fly

    ItemID: 264

    "Revenge fly"

    Quality: 3

    A yellow orbital fly that will block shots and when Isaac gets hit, will seek out the nearest enemy and attack it

    If the fly is in its attacking state and there are no longer any enemies in range, it will return to Isaac and go back to being a defensive orbital

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive, Familiar

      Item Pool: Item Room, Key Beggar

    * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, golden, yellow, glow

  • Dry Baby

    ItemID: 265

    "Immortal friend"

    Quality: 3

    A familiar that follows Isaac and blocks any shots that hit it

    If a projectile is blocked by Dry Baby, he has a 10% chance to activate the Necronomicon effect, dealing 40 damage to the entire room

    The chance to activate the effect is not changed by your Luck stat

    Can drop while destroying skulls in the Depths and Necropolis floors

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, dry baby is best baby, northernlion, fat skeleton, white, grey, gray

  • Juicy Sack

    ItemID: 266

    "Sticky babies"

    Quality: 2

    A familiar that follows isaac around dropping white creep which slows down enemies that walk over it

    Spawns 1-2 familiar blue spiders after every room

    Blue Spiders do x2 of Isaac's damage

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, white, ball, dripping

  • Robo-Baby 2.0

    ItemID: 267

    "We worked out all the kinks"

    Quality: 0

    A familiar that is controlled via the arrow keys and will automatically fire a laser if anything is in its line of sight

    Robo-Baby 2.0's lasers deal 3.5 damage per hit

    UNLOCK: Unlock this item by beating Challenge #16 (Computer Savvy)

      Type: Passive, Familiar

      Item Pool: Item Room

    * robo baby 2.0, item room, treasure room, item room pool, red, eyes, grey, gray, robot

  • Rotten Baby

    ItemID: 268

    "Infested friend"

    Quality: 3

    A familiar which follows Isaac and spawns a blue flies as you're firing tears

    Rotten Baby can only create one fly at a time, meaning if he has created a fly he cannot make another until it is used

    Blue Flies do double your tear damage

    Counts as 1 of 3 familiar items needed towards the Conjoined transformation

      Type: Passive, Familiar

      Item Pool: Item Room, Devil Room

    * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, dead, baby, green, red, bloody

  • Headless Baby

    ItemID: 269

    "Bloody friend"

    Quality: 1

    A familiar that follows Isaac and leaves blood creep on the floor as it floats, hurting enemies that walk over it for 2 damage per tick

    Counts as 1 of 3 familiar items needed towards the Conjoined transformation

      Type: Passive, Familiar

      Item Pool: Item Room, Devil Room

    * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, bloody, red, pink, purple

  • Leech

    ItemID: 270

    "Blood sucker"

    Quality: 1

    Spawns a familiar leech on the ground that hunts down enemies and heals you for half a heart each time it eats one

    The Leech deals 1.5 contact damage per tick

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, grey, gray, worm

  • Mystery Sack

    ItemID: 271

    "?"

    Quality: 2

    A bag that follows Isaac and drops a random heart, coin, bomb or key every 5-6 rooms (alternating, 5 rooms then 6, then repeats)

    Can drop any kind of heart, coin, bomb or key

    UNLOCK: Unlock this item by beating the Dark Room with Eden

      Type: Passive, Familiar

      Item Pool: Item Room, Beggar, Secret Room

    * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, secret room pool, item room, treasure room, item room pool, mysterious sack, multiple sacks, bag, pouch, purple, question mark

  • BBF

    ItemID: 272

    "Big beautiful fly"

    Quality: 1

    A large familiar black fly that bounces around the room, exploding on contact with enemies dealing 70 damage

    Does not explode if it hits Isaac, however if it explodes on an enemy while Isaac is in range, he will take damage

    Respawns after 10 seconds or by moving to another room

    Picking up this item as well as 2 other fly-type items will allow you to transform into Lord of the Flies

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, heart, smile

  • Bob's Brain

    ItemID: 273

    "Explosive thoughts"

    Quality: 1

    A green brain that launches in the direction you are firing your tears and will explode on contact with enemies, dealing damage and poisoning anything in the blast radius

    Bob's Brain deals 100 damage and applies a poison damage over time effect, which deals double your tear damage per tick

    Regenerates over time

    Will hurt Isaac if he is in the blast radius

    Counts as 1 of 3 poison items needed towards the Bob transformation

    REPENTANCE - Bob's Brain now has an increased delay before becoming available when entering rooms. Explosion damage has increased to 100 (from 60).

      Type: Passive, Familiar

      Item Pool: Item Room, Rotten Beggar

    * golden chest pool, gold chest pool, item room, treasure room, item room pool, green, ball, bad damage, bobs brain

  • Best Bud

    ItemID: 274

    "Sworn protector"

    Quality: 0

    When Isaac takes damage, a white attack fly will spawn that orbits him at a similar distance to the Distant Admiration fly

    The fly orbits a lot faster than Distant Admiration or Forever Alone and deals 10 damage per tick

    Picking up this item as well as 2 other fly-type items will allow you to transform into Lord of the Flies

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

    REPENTANCE - Best Bud's contact damage has been increased to 10 (from 5)

      Type: Passive, Orbital

      Item Pool: Item Room, Key Beggar

    * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, the lost item pool, white

  • Lil Brimstone

    ItemID: 275

    "Evil friend"

    Quality: 3

    A familiar that follows Isaac and can fire up and charge brimstone shots, exactly how the normal Brimstone item works but with less damage

    Each laser deals 2.5 damage per tick, up to 8 times for a total of 31.5 damage

    A familiar found in the devil room

    REPENTANCE - Lil Brimstone is now unable to start charging until he is finished attacking. Beam damage has been decreased to 2.5 over 8 ticks (from 3.5 over 9 ticks)

      Type: Passive, Familiar

      Item Pool: Item Room, Devil Room

    * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, horns, baby, smile, lil' brimstone

  • Isaac's Heart

    ItemID: 276

    "Protect it"

    Quality: 0

    Prevents Isaac from taking any damage, but instead summons a familiar heart that follows you around. If the heart is hit, Isaac will take damage

    Most enemies will target the heart over Isaac himself

    Blood donation machines and devil beggars can be used for free. Spikes and Curse Rooms no longer deal damage

    Sharp Plug becomes useless with this item, due to how damage is prevented on Isaac's body

    REPENTANCE - Isaac's Heart has a charge attack, which pushes enemies away and fires blood tears in all directions. It will attempt to hide behind you when shooting. It also no longer prevents damage from self-harming mechanics e.g. Blood Donation machines

    UNLOCK: Unlock this item by beating the Isaac boss with The Lost

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, red, isaacs heart

  • Lil Haunt

    ItemID: 277

    "Fear him"

    Quality: 1

    A familiar ghost that follows Isaac around and chases enemies close-by, damaging them for 2 contact damage and causing a fear effect

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, white, lil' haunt

  • Dark Bum

    ItemID: 278

    "He wants to take your life"

    Quality: 4

    A familiar beggar similar to Bum Friend that follows Isaac and collects red hearts, giving Isaac black hearts, pills, cards, runes or spiders in return

    For every 1.5 red hearts he takes, he will give a reward

    Counts as 1 of 3 bum items needed towards the Super Bum transformation

    REPENTANCE - Dark Bum now has a chance to drop pills, cards, or runes. If he drops a heart, it will always be a black heart

      Type: Passive, Familiar

      Item Pool: Item Room, Devil Room, Demon Beggar

    * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, celebrate good times come on, the lost item pool, qt 3.14, dark bum, otp, damn it reddit, horns, grey, gray, smile

  • Big Fan

    ItemID: 279

    "Fat protector"

    Quality: 2

    A very large orbital that moves around Isaac very slowly, blocking shots and dealing 2 contact damage per tick

    Affects the speed of all other orbitals, slowing them down a lot (NOTE: This effect does not happen until you get a new orbital after Big Fan)

    Does not count as one of your three standard orbital slots

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive, Orbital

      Item Pool: Item Room

    * item room, treasure room, item room pool, fat, brown

  • Sissy Long Legs

    ItemID: 280

    "She loves you"

    Quality: 1

    An adorable friendly blue spider that walks around the room laying other blue spiders which attack enemies

    Blue Spiders do x2 of Isaac's damage

    She can only spawn a maximum of up to 5 spiders at a time and will only do so while there are enemies in the room

    REPENTANCE - Sissy Longlegs now charms enemies upon contact

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, qt 3.14, dark bum, otp, damn it reddit, blue, derpface

  • Punching Bag

    ItemID: 281

    "Scape goat"

    Quality: 1

    Spawns a friendly Mulligan that walks around the room. Mulligan can be hit by enemy projectiles, making him a good shield

    Enemies will sometimes target the Mulligan if he is closer

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, sad, baby, lumpy, brown, pink

  • How To Jump

    ItemID: 282

    "It's time you learned how"

    Quality: 1

    When used, makes Isaac leap in the air, similar to the leaper enemies

    Maintains momentum if you are already moving in the same direction

    If you already have an item which gives you flying, this item becomes a dash effect instead

    Can be used in the Isaac boss fight to jump over the beams of light he spawns

      Type: Active

      Recharge Time: Instant

      Item Pool: Item Room, Library

    * library pool, library room, book room pool, item room, treasure room, item room pool, mario, cartridge, nes, grey, gray, orange

  • D100

    ItemID: 283

    "REEROLLLLL!"

    Quality: 3

    When used, rerolls each item you currently own into another item room pool item and any pedestal items and pickups in the room

    Has the combined uses of the D4, D6 and D20

    REPENTANCE - Full run reroll effects (such as D4) are now able to remove heart containers and transformations if losing the respective items during the reroll

    UNLOCK: Unlock this item by beating Boss Rush with The Lost

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, deathstar, death star, dice pip, white, circle, sphere

  • D4

    ItemID: 284

    "Reroll into something else"

    Quality: 3

    When used, the D4 re-rolls each item you currently have into another random item from the same item pool

    If you have an item with no room pool (e.g. Blood Bag) it will be rerolled into a random Item Room item

    Cannot remove Azazel's Brimstone laser, or The Lost's Holy Mantle

    REPENTANCE - Full run reroll effects (such as D4) are now able to remove heart containers and transformations if losing the respective items during the reroll

    UNLOCK: Unlock this item by blowing up 30 slot machines

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, dice pip, starting, pyramid, green, triange

  • D10

    ItemID: 285

    "Rerolls enemies"

    Quality: 0

    When used, rerolls all enemies in the room which are currently alive into another random type of enemy

    Dangerous to use in early floors, it could replace a basement enemy with something usually found on later floors

    Cannot reroll mini-bosses or bosses

    REPENTANCE - D10 now attempts to reroll enemies into enemies of similar health

      Type: Active

      Recharge Time: 1 room

      Item Pool: Item Room

    * item room, treasure room, item room pool, DIO, dice pip, orange, brown, turban

  • Blank Card

    ItemID: 286

    "Card Mimic"

    Quality: 2

    When used, copies the effect of the card you are currently holding without consuming it

    The charge time of this item depends on the quality of the card you're holding

    Using this with the ? card will teleport you to the I AM ERROR room

    REPENTANCE - Blank Card now only works with cards. Charge time is now dependent on the held card, and will update with each activation

    UNLOCK: Unlock this item by beating the Isaac boss with Eden

      Type: Active

      Recharge Time: Varies

      Item Pool: Shop, Secret Room

    * secret room pool, shop room pool, shop item pool, item room, treasure room, item room pool, white, square

  • Book of Secrets

    ItemID: 287

    "??????"

    Quality: 0

    When used, you have a chance of getting one of the three following effects: Treasure Map (floor layout), Compass (map icons) or Blue Map (secret room locations)

    Counts as 1 of 3 book items needed towards the Bookworm transformation

    REPENTANCE - Book of Secrets now avoids giving mapping effects that the player already has. If the player has all mapping effects, it grants the "I can see forever!" effect for the floor

    UNLOCK: Unlock this item by beating Satan with Eden

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Item Room, Library, Secret Room

    * library pool, library room, book room pool, secret room pool, item room, treasure room, item room pool, question mark book, white

  • Box of Spiders

    ItemID: 288

    "It's a box of spiders"

    Quality: 1

    When used, spawns 4-8 friendly blue spiders on the floor

    Blue Spiders do x2 of Isaac's damage

    Counts as 1 of 3 spider items needed towards the Spider Baby transformation

    REPENTANCE - Used to give 1-4 spiders per use

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room

    * item room, treasure room, item room poolgrey, gray

  • Red Candle

    ItemID: 289

    "Flame on"

    Quality: 2

    Allows you to fire a red flame infront of you, similar to the Blue Candle item, however the flame will stay 10 seconds

    Each flame deals 125 total damage before it disappears

    The flame will shrink in size when deals damage to something and eventually disappear

    REPENTANCE - Red Candle flames now time out after ten seconds and automatically extinguish. They also no longer block player attacks or get extinguished by them

    UNLOCK: Unlock this item by donating 400 pennies to the Shop

      Type: Active

      Recharge Time: Timed (A few seconds)

      Item Pool: Shop

    * shop room pool, shop item pool

  • The Jar

    ItemID: 290

    "Save your life"

    Quality: 0

    Isaac can now pick up hearts while at full health, which will be stored in the Jar and can be spawned again using the spacebar

    Up to 4 hearts can be stored in The Jar

    Soul hearts and black hearts cannot be stored

    If used in a Black heart or Eternal heart super secret room, it will spawn the relevant heart

      Type: Active

      Recharge Time: Instant

      Item Pool: Shop

    * shop room pool, shop item pool, the lost item pool, glass

  • FLUSH!

    ItemID: 291

    "..."

    Quality: 1

    When used, turns every normal enemy in the room into poop!

    Does not work on mini-bosses and bosses

    Kills poop bosses when used - Dingle, Dangle and Brownie

    Counts as 1 of 3 poop items needed towards the Oh Crap transformation

      Type: Active

      Recharge Time: 4 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, silver spoon handle, grey, gray, white, toilet

  • Satanic Bible

    ItemID: 292

    "Reusable evil... but at what cost?"

    Quality: 4

    When used, gives Isaac +1 Black Heart

    When depleted, Black Hearts deal 40 damage to the entire room, in a Necronomicon style effect

    Counts as 1 of 3 book items needed towards the Bookworm transformation

    REPENTANCE - Using this book once before the boss dies, causes the boss item on the current floor to become a devil deal instead, where it will cost heart containers to pick up. Taking this item does not affect your devil/angel room chances.

    UNLOCK: Unlock this item by beating the Isaac boss with Azazel

      Type: Active

      Recharge Time: 4 rooms

      Item Pool: Item Room, Library, Devil Room

    * the satanic bible library pool, library room, book room pool, devil pool, devil room pool, devil deal, item room, treasure room, item room pool, the lost item pool, pentagram, star, grey, gray, red

  • Head of Krampus

    ItemID: 293

    "Krampus rage"

    Quality: 2

    When used, fires a 4 way brimstone laser in all cardinal directions, dealing a lot of damage to any enemies

    Laser damage does not scale with your damage stat

    Has a chance to drop after you beat Krampus

    If you get close enough to an enemy that has a large hitbox, you can hit it with 2 of the laser beams, allowing you to deal more damage

    REPENTANCE - Head of Krampus now deals 10 damage over 19 ticks (from 22 damage over 20 ticks). Charge time has been reduced to 3 (from 6)

    UNLOCK: Unlock this item by beating Krampus (Krampus is unlocked by taking 20 devil deal items)

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: None (Krampus only)

    *, horns, grey, gray, white, red, dead, tongue, krampus head

  • Butter Bean

    ItemID: 294

    "Reusable knockback"

    Quality: 0

    When used, farts on nearby enemies and knocks them backwards away from Isaac

    Allows you to reflect projectiles away from Isaac

    REPENTANCE - Butter Bean now knocks back enemies and projectiles with significantly more force. If a pushed enemy hits a rock or wall forcefully enough, they take 10 damage

    UNLOCK: Unlock this item by destroying 100 poops

      Type: Active

      Recharge Time: Timed (A few seconds)

      Item Pool: Item Room, Beggar

    * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, treasure room, item room pool, white

  • Magic Fingers

    ItemID: 295

    "Pay to play"

    Quality: 1

    Upon use, consumes a coin and deals damage to everything in the room

    Damage dealt is equal to your tear damage * 2 + 10

    REPENTANCE - Damage buffed, previously it was damage * 2. Magic Fingers ignores the +40 flat damage with Ipecac, removing the synergy between these two

      Type: Active

      Recharge Time: Instant

      Item Pool: Item Room, Shop

    * shop room pool, shop item pool, item room, treasure room, item room pool, tissue, box, yellow, grey

  • Converter

    ItemID: 296

    "Convert your soul"

    Quality: 1

    When used, converts 1 soul/black heart into 1 red heart container

    This item will take from your soul hearts first

    REPENTANCE - Converter now only costs one soul heart to use (previously costed two)

      Type: Active

      Recharge Time: Instant

      Item Pool: Shop

    * shop room pool, shop item pool, the lost item pool, blue, gray, grey, yellow, sprocket

  • Pandora's Box

    ItemID: 297

    "? ?"

    Quality: 2

    When used, this item will spawn a set of items or consumables based on which chapter you are currently on

    Basement 1: 2 Soul hearts. Basement 2: 2 Bombs + 2 Keys

    Caves 1: 1 Boss Item. Caves 2: 1 Boss Item + 2 Soul Hearts

    Depths 1: 4 Soul hearts. Depths 2: 20 coins

    Womb 1: 2 Boss Items. Womb 2: Bible

    Blue Womb: Nothing!. The Void: Nothing!

    Sheol: 1 Devil Room Item + 1 Black Heart. Cathedral: 1 Angel Room Item + 1 Eternal Heart

    Chest: 1 coin. Dark Room: Nothing!

    Home: Gives Red Key.

    Pandora's Box considers XL floors to always be the first floor of a chapter

    Alternative floors drop the same stuff e.g. Corpse II drops same as Womb II

    UNLOCK: Unlock this item by beating the Dark Room with Lazarus

      Type: Active

      Recharge Time: One time use

      Item Pool: Shop, Red Chest

    * red chest pool, red chest item pool, shop room pool, shop item pool, blue box, pandoras box

  • Unicorn Stump

    ItemID: 298

    "You feel stumped"

    Quality: 1

    When used, turns Isaac invincible and gains +0.28 speed for a 5 seconds

    You cannot fire tears while the stump is active

    Very similar to the My Little Unicorn item but does not deal contact damage

    When used with Mom's Knife, you can still deal contact damage but will be unable to change the way the knife faces while the effect is active

      Type: Active

      Recharge Time: 1 room

      Item Pool: Item Room

    * item room, treasure room, item room pool, white, lump, grey, gray, blob

  • Taurus

    ItemID: 299

    "Speed down + rage is building"

    Quality: 1

    -0.3 Speed Down

    While in a hostile room your speed raises at a rate of +0.065 per game tick

    When you hit a speed stat of 2.0, Isaac will gain an invincibility effect for 5 seconds, increasing speed and allowing him to run into enemies to deal 40 contact damage per hit

    The time it takes for the effect to activate becomes shorter with a higher base Speed stat

    One of the twelve zodiac items available in the game

      Type: Passive

      Item Pool: Item Room

    * astrology, astronomy, item room, treasure room, item room pool, blue, glow, circle, horns

  • Aries

    ItemID: 300

    "Ramming speed"

    Quality: 1

    +0.25 Speed up

    Gives huge horns which stick out, allowing you to deal 18 contact damage if you hit something with enough speed

    Will not deal contact damage unless you are moving fast enough (at least 0.8 speed)

    One of the twelve zodiac items available in the game

    REPENTANCE - Aries now prevents receiving contact damage if ramming and killing enemies at full speed

      Type: Passive

      Item Pool: Item Room

    * astrology, astronomy, item room, treasure room, item room pool, black, blue, cyan, glow

  • Cancer

    ItemID: 301

    "HP up + you feel protected"

    Quality: 3

    +3 Soul Hearts

    After getting hit once, you gain a damage reduction for the rest of the room similar to The Wafer item (-50% damage taken)

    One of the twelve zodiac items available in the game

      Type: Passive

      Item Pool: Item Room

    * astrology, astronomy, item room, treasure room, item room pool, cyan, black, the lost item pool, blue, glow, 69

  • Leo

    ItemID: 302

    "Stompy"

    Quality: 1

    Isaac increases in size, gets a lion's mane and now has the ability to crush rocks by walking over them

    Crushed rocks and poop can fill holes if you walk in their direction

    Allows you to crush Red Poops and sometimes not take damage. However, If you also have flying you will always take damage

    One of the twelve zodiac items available in the game

    Counts as 1 of 3 size-increasing items needed towards the Stompy transformation

      Type: Passive

      Item Pool: Item Room

    * astrology, astronomy, item room, treasure room, item room pool, blue, glow, circle, bomb

  • Virgo

    ItemID: 303

    "You feel refreshed and protected"

    Quality: 2

    A random chance when you take damage to get an invincibility shield for 7 seconds

    The chance to get an invincibility shield is affected by your luck stat and at +10 Luck it will activate every time you get hit

    Converts all negative pills into their positive counterparts e.g. Stat Down becomes Stat Up, 'Bad Trip' turns into 'Balls of Steel' and 'Amnesia' turns into 'I can see forever'

    One of the twelve zodiac items available in the game

      Type: Passive

      Item Pool: Item Room

    * astrology, astronomy, item room, treasure room, item room pool, blue glow, m

  • Libra

    ItemID: 304

    "You feel balanced"

    Quality: 1

    Gives you 6 keys, 6 bombs and 6 coins

    Balances out your main stats to bring the high and low stats closer to an average value

    All future stat upgrading items will now instead spread out across all other stats. For example, an item which usually gives +1 Damage would instead give a small 'all stats up'

    Stats effected by this item are: Damage, Tears, Range, Speed

    When taken with another item which gives an extreme value in a certain stat (e.g. Soy Milk) can lead to interesting synergies

    One of the twelve zodiac items available in the game

      Type: Passive

      Item Pool: Item Room

    * astrology, astronomy, item room, treasure room, item room pool, ohm, blue, glow

  • Scorpio

    ItemID: 305

    "Poison tears"

    Quality: 2

    Isaac's tears turn bright green and always apply a poison effect to enemies which deals a total of double your tear damage

    This is essentially a superior version of The Common Cold item

    One of the twelve zodiac items available in the game

      Type: Passive

      Item Pool: Item Room

    * astrology, astronomy, item room, treasure room, item room pool, m, tail, blue, glow

  • Sagittarius

    ItemID: 306

    "Penetrative shot + speed up"

    Quality: 3

    +0.2 Speed Up

    Grants piercing tears

    Tears do not travel through rocks with this item

    One of the twelve zodiac items available in the game

      Type: Passive

      Item Pool: Item Room

    *astrology, astronomy, item room, treasure room, item room pool, nys, notyoursagittarius, blue, glow, arrow, cross

  • Capricorn

    ItemID: 307

    "All stats up"

    Quality: 3

    +1 HP Up

    +0.5 Damage Up

    -1 Tear Delay (Tears Up)

    +0.1 Speed Up

    +1.5 Range Up

    +1 Key, +1 Bomb, +1 Coin

    Heals one red heart container when picked up

    One of the twelve zodiac items available in the game

      Type: Passive

      Item Pool: Item Room

    * astrology, astronomy, item room, treasure room, item room pool, cyan, black, blue, glow, n, tail

  • Aquarius

    ItemID: 308

    "A trail of tears"

    Quality: 0

    Leaves a trail of tears on the floor behind Isaac which damages enemies that walk over it for 2 damage per tick

    One of the twelve zodiac items available in the game

    REPENTANCE - Aquarius now synergizes with tear effects

      Type: Passive

      Item Pool: Item Room

    * astrology, astronomy, item room, treasure room, item room pool, black, blue, cyan, blue, glow, lightning, bolt, hot garbage

  • Pisces

    ItemID: 309

    "Tears up + knockback shot"

    Quality: 2

    -1 Tear Delay (Tears Up)

    x1.25 Tear Size Up

    Tears now have a bigger knockback effect, which pushes enemies backwards

    One of the twelve zodiac items available in the game

      Type: Passive

      Item Pool: Item Room

    * astrology, astronomy, item room, treasure room, item room pool, h, blue, glow

  • Eve's Mascara

    ItemID: 310

    "Shot speed down + DMG up"

    Quality: 1

    x2 Damage Multiplier

    Tears Down by exactly half (Tear delay * 2)

    -0.5 Shot Speed Down

    The tears down from this item is a x2.0 multiplier after the formula, meaning it will always halve your tear rate (Unless you have Monstro's Lung or Soy Milk)

    UNLOCK: Unlock this item by beating Boss Rush with Eve

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, makeup, make up, black, grey, gray, square, eves mascara

  • Judas' Shadow

    ItemID: 311

    "Sweet revenge"

    Quality: 4

    When you die with this item, you respawn in the previous room as Dark Judas with 2 black hearts for health

    Dark Judas has a damage multiplier of 2.00 (double Isaac's damage) and an additional +0.1 Speed

    Dark Judas is considered a separate character by the game, however he can be used to unlock Judas' secrets/achievements

    REPENTANCE - Dark Judas can no longer gain red heart containers, HP upgrades give soul hearts instead

    UNLOCK: Unlock this item by beating Boss Rush with Judas

      Type: Passive

      Item Pool: Devil Room

    * devil pool, devil room pool, devil deal, item room, treasure room, item room pool judas shadow

  • Maggy's Bow

    ItemID: 312

    "HP up + you feel healthy"

    Quality: 2

    +1 HP Up

    Heals one red heart container when picked up

    All future red hearts now heal for double. Half hearts heal a whole heart and full hearts heal 2 red hearts

    UNLOCK: Unlock this item by beating Boss Rush with Maggy

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, the lost item pool, pink, purple, candy

  • Holy Mantle

    ItemID: 313

    "Holy shield"

    Quality: 4

    Each time you enter a new room, damage is negated for the first time you get hit

    Can be used to go in and out of a Curse Room without taking damage

    Counts as 1 of 3 angel items needed towards the Seraphim transformation

    The Lost starts with this item after donating 879 coins to the Greed Donation Machine.

    REPENTANCE - The Lost's Holy Mantle can no longer be re-rolled using an item like D4. The invulnerability frames are way less when playing as The Lost

      Type: Passive

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, starting, blue, white, glow, cross

  • Thunder Thighs

    ItemID: 314

    "HP + speed down + you feel strong"

    Quality: 1

    +1 HP Up

    -0.4 Speed Down

    You can now break obstacles by walking over them

    Heals one red heart container when picked up

    Holes in the ground can be filled by crushing adjacent rocks, similar to how this can be done with bombs

    Allows you to crush Red Poops and sometimes not take damage. However, If you also have flying you will always take damage

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, cheetos, cheese, grey, gray, orange, jar

  • Strange Attractor

    ItemID: 315

    "Magnetic tears"

    Quality: 0

    Enemies and pickups (keys, bombs etc.) are now magnetically attracted to Isaac's tears

    Can cause some enemies to have unpredictable movement

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, grey, gray, magnet

  • Cursed Eye

    ItemID: 316

    "Cursed charged shot"

    Quality: 0

    Tears are now charged up and fired rapidly in a burst of up to 5 shots at once

    The amount of tears fired in the charge depends on how long you charge for

    The eye has three states, white (not firing), black (first second of charging) and blinking between black and white. If you get hit while Cursed eye is a solid black colour you are guaranteed to be teleported to another random room on the floor. If you get hit in either of the other 2 states you will not be teleported

    The Black Candle item will remove the Cursed Eye's teleportation effect

    REPENTANCE - Burst now has 5 shots instead of 4

      Type: Passive, Tear Modifier

      Item Pool: Item Room, Secret Room

    * secret room pool, item room, treasure room, item room pool, white, circle, pearl

  • Mysterious Liquid

    ItemID: 317

    "Toxic splash damage"

    Quality: 1

    When Isaac's tears hit anything, they leave a green toxic creep on the floor that damages enemies for 1 damage per tick

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, mystery liquid, grey, gray, green

  • Gemini

    ItemID: 318

    "Conjoined friend"

    Quality: 1

    A familar that is attached to Isaac, which will seek out and damage any enemies close by for 3 contact damage

    One of the twelve zodiac items available in the game

      Type: Passive, Familiar

      Item Pool: Item Room

    * astrology, astronomy, item room, treasure room, item room pool, blue, glow

  • Cain's Other Eye

    ItemID: 319

    "Near sighted friend"

    Quality: 0

    A familiar eye that bounces around the room slowly and fires tears in the same direction as Isaac

    Cain's Other Eye deals scaling damage equal to Isaac's tear damage

    UNLOCK: Unlock this item by beating Boss Rush with Cain

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, eyeball, white, circle, cataract, cains other eye

  • ???'s Only Friend

    ItemID: 320

    "Controlled friend"

    Quality: 2

    A familiar fly that can be moved around via use of the arrow keys dealing 2.5 contact damage per tick, similar to the Ludovico Technique's mechanic

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

    UNLOCK: Unlock this item by beating Boss Rush with Blue Baby

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, blue fly, big fly, blue baby's only friend, fat, dead, ???s only friend

  • Samson's Chains

    ItemID: 321

    "The ol' ball and chain"

    Quality: 1

    An iron ball and chain attached to Isaac, similar to Guppy's Hairball that you can fling around to deal 5 damage per tick

    The ball will block enemy shots and can also destroy environmental objects such as rocks, mushrooms and skulls

    Does not decrease your movement speed stat at all however the ball has to be dragged around causing Isaac to slow down slightly when the chain is fully extended

    UNLOCK: Unlock this item by beating Boss Rush with Samson

      Type: Passive, Familiar

      Item Pool: Item Room, Secret Room

    * secret room pool, item room, treasure room, item room pool, grey, gray, shackle

  • Mongo Baby

    ItemID: 322

    "Mongo friend"

    Quality: 2

    A familiar that will follow Isaac and copy the effect of one of your other familiars

    If you don't have any other familiars, he will just shoot normal tears

    Counts as 1 of 3 familiar items needed towards the Conjoined transformation

    REPENTANCE - Removed the double damage multiplier on Mongo Baby's attacks

      Type: Passive, Familiar

      Item Pool: Item Room

    * item room, treasure room, item room pool, pink, blue, grey, gray

  • Isaac's Tears

    ItemID: 323

    "Collected tears"

    Quality: 0

    A spacebar item that fires 8 of Isaac's tears in a circle around him

    Tears spawned from this item keep most effect that Isaac currently has applied to his tears

    UNLOCK: Unlock this item by beating the Isaac boss with Isaac

      Type: Active

      Recharge Time: 1 bar per tear fired

      Item Pool: Item Room

    * item room, treasure room, item room pool, glass, blue, water, isaacs tears

  • Undefined

    ItemID: 324

    "Undefined"

    Quality: 2

    Upon use, teleports you to one of the following rooms at random: Item room, Secret room, Super secret room, the I AM ERROR room or the Black Market (very low chance)

    There are no I AM ERROR rooms on the final floors, preventing looping with this item

    UNLOCK: Unlock this item by beating Boss Rush with Eden

      Type: Active

      Recharge Time: 6 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, pink, purple, red, broken

  • Scissors

    ItemID: 325

    "Lose your head"

    Quality: 0

    When used will cut your head from your body. Isaac's head will remain stationary and fire tears. His body can be controlled and spews blood nearby

    Tears fired by the head do a flat 3.5 damage and don't scale

    REPENTANCE - Scissors has been redesigned. The stationary head is now affected by Isaac's stats and attack modifiers, and the body will spew a controllable fountain of blood shots. Charge time increased to 4 (from 2)

    UNLOCK: Unlock this item by dying 100 times

      Type: Active

      Recharge Time: 4 rooms

      Item Pool: Item Room

    * item room, treasure room, item room pool, grey, gray

  • Breath of Life

    ItemID: 326

    "Invincibility at a cost"

    Quality: 0

    While you hold the spacebar down with this item, it will empty the charge bar gradually. When the charge bar gets to zero it will grant you a brief period of invincibility

    If the spacebar is held for too long (about 1 second) when it has no charge, you will take damage

    The invincibility effect is shown via a rapid flashing animation

      Type: Active

      Recharge Time: Timed (1 bar per second)

      Item Pool: Angel Room

    * angel room pool, god room pool, angel room item, white, blue, ball, circle

  • The Polaroid

    ItemID: 327

    "Fate chosen"

    Quality: 2

    After taking damage, if you have half a red heart or less, The Polaroid will give you an invincibility shield for 5 seconds

    Grants access to the Chest floor

    Allows you to open the door at the beginning of Depths II that leads to the Mausoluem

    When unlocked, is guaranteed to drop after the Mom's Foot boss fight

    UNLOCK: Unlock this item by beating Isaac in the Cathedral 5 times

      Type: Passive

      Item Pool: None (Mom's foot boss only)

    *, photo, family, kodak

  • The Negative

    ItemID: 328

    "Fate chosen"

    Quality: 1

    After taking damage, if you have half a red heart or less, The Negative will deal 40 damage to all enemies in the room

    Gives you access to the Dark Room floor

    Allows you to open the door at the beginning of Depths II that leads to the Mausoluem

    When unlocked, is guaranteed to drop after the Mom's Foot boss fight

    REPENTANCE - This item gives a +1.0 Damage Up now

    UNLOCK: Unlock this item by beating Satan in Sheol 5 times

      Type: Passive

      Item Pool: None (Mom's foot boss only)

    * mom's foot, mom fight, mom boss, dark room, photo, family, kodak, inverted

  • The Ludovico Technique

    ItemID: 329

    "Controlled tears"

    Quality: 3

    You no longer shoot tears and instead now control a single large tear with the arrow keys

    Items which increase your tears stat will cause the tear to deal damage at a faster rate

    Items which increase your shot speed cause the tear to travel faster across the screen

    Ludo and Brimstone create a large controllable red ring of death that does massive damage to anything in its path

    Taking this with Mom's Knife allows you to remote control the knife around the room, dealing huge damage

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, eye, pink, grey, gray, robot

  • Soy Milk

    ItemID: 330

    "DMG down + tears way up"

    Quality: 2

    Very high Tears Up: (delay / 4) - 2

    -80% Damage Down

    x0.5 Tear Size

    REPENTANCE - Soy Milk tears now cause drastically less knockback

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    * item room, treasure room, item room pool, white, glass, square

  • GodHead

    ItemID: 331

    "God tears"

    Quality: 4

    Isaac's tears become homing and have a large aura around them, which will deal damage to anything inside its radius

    +0.5 Damage Up

    +1.2 Range Up

    -0.3 Tears Down

    -0.3 Shot Speed Down

    +0.8 Tear Height

    UNLOCK: Unlock this item by beating all bosses and completing all post-it note marks in hard mode with The Lost character

      Type: Passive, Tear Modifier

      Item Pool: Angel Room

    * angel room pool, god room pool, angel room item, yellow, blue, red, triangle, all seeing eye

  • Lazarus' Rags

    ItemID: 332

    "Eternal life?"

    Quality: 1

    Gives Isaac an extra life on death, exactly the same as Lazarus' default respawn effect

    When you die with this item, you respawn in the same room with 1 heart and the Anemic item

    The game considers you to be a different character (Lazarus II) when this effect activates

    UNLOCK: Unlock this item by beating the Isaac boss with Lazarus

      Type: Passive

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, starting, bloody, white, bandages, lazarus rags

  • The Mind

    ItemID: 333

    "I know all"

    Quality: 3

    Gives Isaac a full mapping effect, revealing the entire floor and locations of all secret rooms

    UNLOCK: Unlock this item by beating Satan with The Lost

      Type: Passive

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, yellow, white, triangle

  • The Body

    ItemID: 334

    "I feel all"

    Quality: 3

    +3 Health Up

    The three heart containers are pre-filled with red hearts

    UNLOCK: Unlock this item by beating the Chest with The Lost

      Type: Passive

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, real platinum god, the lost item pool

  • The Soul

    ItemID: 335

    "I am all"

    Quality: 3

    +2 Soul Hearts

    Enemy projectiles will now slowly curve away from Isaac and avoid hitting him

    UNLOCK: Unlock this item by beating Dark Room with The Lost

      Type: Passive

      Item Pool: Item Room, Angel Room

    * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, blue, white, triangle

  • Dead Onion

    ItemID: 336

    "Toxic aura tears"

    Quality: 3

    Isaac's tears become large, brown and will penetrate all objects and enemies (piercing + spectral)

    -0.25 Range Down

    -0.4 Shot Speed Down

    -0.5 Tear Height

    x1.5 Tear Size

    Despite the increase in tear size, Dead Onion does NOT increase your damage stat. It also doesn't do poison damage despite having the tagline 'toxic aura tears'

      Type: Passive

      Item Pool: Item Room

    * item room, treasure room, item room pool, brown, pink, purple, plant

  • Broken Watch

    ItemID: 337

    "I think its broken"

    Quality: 1

    Upon entering every 4th unexplored room, the Broken Watch will either slow down or speed up all enemies in the room

    The slow effect is much more common than the speed up

    An item only found in the Shop item pool

      Type: Passive

      Item Pool: Shop

    * shop room pool, shop item pool, blue, grey, gray, smashed, clock, broken stop watch, broken stopwatch

  • Boomerang

    ItemID: 338

    "It will never leave you"

    Quality: 1

    A blue boomerang which can be thrown in a similar fashion to Mom's Knife, to stun any enemies it hits and deal damage

    The damage dealt by the Boomerang is equal to double your tear damage

    The boomerang can also be used to grab pickups and consumables from a distance, similar to the legend of zelda boomerang

    The range of the boomerang is affected by range, with number one the distance is very short and makes the item a lot less effective

    The Boomerang can be used to kill shopkeeper corpses, allowing you to farm their drops for coins, items, Steam Sale etc

    REPENTANCE - Boomerang is now piercing, and has far less downtime between throwing it and being able to fire tears again

      Type: Active

      Recharge Time: Timed (A few seconds)

      Item Pool: Shop

    * shop room pool, shop item pool, crescent, moon, blue, grey, gray

  • Safety Pin

    ItemID: 339

    "Evil up + range + shot speed"

    Quality: 1

    +5.25 Range Up

    +0.16 Shot Speed Up

    +1 Black Heart

    +0.5 Tear Height

    When depleted, Black Hearts deal 40 damage to the entire room, in a Necronomicon style effect

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, grey, gray, punk

  • Caffeine Pill

    ItemID: 340

    "Speed up + size down"

    Quality: 1

    +0.3 Speed Up

    Decreases the size of Isaac, and your player hitbox, making you less likely to be hit

    Gives you a random pill when picked up

    An item only found in the boss room pool

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, pro plus, tablet, medicine, white

  • Torn Photo

    ItemID: 341

    "Tears + shot speed up"

    Quality: 3

    +0.7 Tears Up

    +0.16 Shot Speed Up

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    * boss room pool, boss room item, grey, orange, family, picture

  • Blue Cap

    ItemID: 342

    "HP + tears + shot speed down"

    Quality: 3

    +1 HP Up

    +0.7 Tears Up

    -0.16 Shot Speed Down

    Heals one red heart container when picked up

    An item only found in the Boss Room pool

    Counts as 1 of 3 mushroom items needed towards the Fun Guy transformation

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, mushroom, fungi, fungus

  • Latch Key

    ItemID: 343

    "Luck up"

    Quality: 2

    +1 Luck Up

    +1 Soul Heart

    Spawns 2 keys on the ground

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest, Key Beggar

    * boss room pool, boss room item, brass, bronze, brown, gold

  • Match Book

    ItemID: 344

    "Evil up"

    Quality: 1

    +1 Black Heart

    +3 Bombs

    When depleted, Black Hearts deal 40 damage to the entire room, in a Necronomicon style effect

    REPENTANCE - Also drops the Match Stick trinket

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    * boss room pool, boss room item, white, red

  • Synthoil

    ItemID: 345

    "DMG up + range"

    Quality: 3

    +1.0 Damage Up

    +5.25 Range Up

    +0.5 Tear Height

    Counts as 1 of 3 syringe items needed towards the Spun transformation

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, syringe, needle, grey, purple, pink

  • A Snack

    ItemID: 346

    "HP up"

    Quality: 1

    +1 HP Up

    Heals one red heart container when picked up

      Type: Passive

      Item Pool: Boss Room

    * boss room pool, boss room item, the lost item pool, dog, biscuit, brown, orange

  • Afterbirth Items (95)

  • Diplopia

    ItemID: 347

    "Double item vision"

    Quality: 3

    A one-time use item which when used, will duplicate any pedestal items or consumables in the current room

    If used in a shop, the duplicated items can be taken for free

    If used on a trinket, another random trinket will spawn instead of a duplicate

    If used in the Boss Rush, all the duplicates can be taken for free as well as one of the original items

    If used in a Devil Room or Black Market, the duplicates can be taken for free

      Type: Active

      Recharge Time: Instant (One time use)

      Item Pool: Shop

    *, white, button, eye

  • Placebo

    ItemID: 348

    "Pill mimic"

    Quality: 2

    When used, copies the effect of the pill you are currently holding without consuming it

    The charge time of this item depends on the quality of the pill you're holding

    Does not copy effects of Cards or Runes

    REPENTANCE - Placebo's charge time is now dependent on the held pill, and will update with each activation

      Type: Active

      Recharge Time: Varies

      Item Pool: Shop, Greed Mode Shop

    *, grey, gray, white, medicine, tablet

  • Wooden Nickel

    ItemID: 349

    "Flip a coin"

    Quality: 1

    When used, has a 50% chance to drop one random type of coin (penny, nickel or dime)

    UNLOCK: Unlock this item by donating 33 coins to the Greed Donation Machine

    UNLOCK: Keeper starts with this item after beating Isaac with Keeper

      Type: Active

      Recharge Time: 1 room

      Item Pool: Shop, Greed Mode Item Room

    * starting, brown, orange, cent,

  • Toxic Shock

    ItemID: 350

    "Mass poison"

    Quality: 3

    With this item, at the start of every room you will deal double your tear damage to the entire room in a poison effect

    Enemies killed now also leave a pool of creep on the ground where they died. This deals 1 damage per tick

    High tear damage will cause this item to become very powerful for rooms with a lot of enemies, since they can die instantly and render the room harmless

    Enemies which spawn after the first few seconds of each room are not affected by this item, e.g. Flies spawned from a Mulligan dying

      Type: Passive

      Item Pool: Item Room

    *, green, glow, biohazard

  • Mega Bean

    ItemID: 351

    "Giga fart!"

    Quality: 1

    When used, the Mega Bean will freeze all enemies in the current room for a couple of seconds, deal 5 damage and poison any enemies in close proximity and send a wave of spikes across the room in the direction you are facing

    The enemies in close range will take 5 damage then have a poison over time effect which deals your tear damage 4 or 6 times

    The spike wave will deal 10 damage to any enemies in contact with it

    Can be used to open secret rooms

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Item Room, Greed Mode Item Room

    *, pink, kidney

  • Glass Cannon

    ItemID: 352

    "Be gentle..."

    Quality: 1

    Glass Cannon allows you to fire one huge spectral tear that deals a lot of damage.

    When taking damage, the cannon will break and remain broken until recharged (Recharge time: 4 rooms)

    When you take damage and the cannon breaks, you take an additional 2 full hearts of damage and gain the Anemic effect for the room.

    The damage done by Glass Cannon is calculated as follows: dmg = (dmg * 10) + 10 (i.e. at base damage of 3.5, that's 45 damage)

    REPENTANCE - This item has been reworked, see above for new effect.

      Type: Active

      Recharge Time: 5 seconds

      Item Pool: Item Room, Greed Mode Item Room

    *, silver

  • Bomber Boy

    ItemID: 353

    "Explosive blast!"

    Quality: 2

    +5 bombs

    Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide)

    This also affects troll bombs

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room, Bomb Beggar

    *, man, face, white

  • Crack Jacks

    ItemID: 354

    "Don't swallow the prize!"

    Quality: 2

    +1 HP Up

    Spawns a random trinket on the floor

    REPENTANCE - Added to the Gold Chest pool

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    *, brown, red, tup, carton, box, golden chest pool, gold chest pool,

  • Mom's Pearls

    ItemID: 355

    "Range + luck up"

    Quality: 2

    +0.38 Range Up

    +1 Luck Up

    +1 Soul Heart

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    *, white, necklace, grey, gray, moms pearls, mom pearls

  • Car Battery

    ItemID: 356

    "Double charge!"

    Quality: 3

    The Car Battery causes your spacebar item to activate twice on each use

    For example, with Yum Heart you would heal 2 full red hearts instead of 1

      Type: Passive

      Item Pool: Shop, Greed Mode Shop

    *, black, box, cube

  • Box of Friends

    ItemID: 357

    "Double your friends"

    Quality: 1

    Upon use, gives you a duplicate of each familiar you have for the current room

    It will not 'double' your familiars as the tagline suggests - if you have 2 of one kind, it will only give you an extra one

    If the familiar only appears when taking damage (i.e. Dead Bird) then Box of Friends will cause it to spawn but won't create duplicates

    This can be used multiple times in the same room to generate more familiars, meaning you can get a level 4 meatboy or bandage girl by using this item 3 times in the same room

    If used when you have no familiars, it will give you a Demon Baby temporarily

    UNLOCK: Unlock this item by beating Greed Mode with Lilith

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Shop, Greed Mode Item Room

    *, gold, black

  • The Wiz

    ItemID: 358

    "Double wiz shot!"

    Quality: 1

    Isaac wears a dunce hat and fires 2 tears at once diagonally, similar to the R U A WIZARD pill tear pattern

    Gives Isaac spectral tears which allows them to travel through objects in the environment (i.e. rocks)

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    * Item Room, Greed Mode Item Room, dunce cap, white, hat, cone

  • 8 Inch Nails

    ItemID: 359

    "Stick it to 'em!"

    Quality: 3

    +1.5 Damage Up

    Replaces Isaac's tears with nails, which have increased knockback

    The increased knockback will also affect Brimstone, which usually has no knockback at all

      Type: Passive, Tear Modifier

      Item Pool: Item Room, Greed Mode Item Room

    *, silver, grey, gray

  • Incubus

    ItemID: 360

    "Dark friend"

    Quality: 4

    Gives you a familiar demon incubus that follows you and shoots tears exactly the same as Isaac's in terms of damage, stats and also effects.

    It will mimic any tear effects you currently have and also copy your current stats, meaning it will fire with the same damage, fire rate and range

    Incubus' tear damage will scale with any future damage ups and stat upgrades you take

    Lilith starts with this item

    REPENTANCE - Incubus deals 25% less damage when used on characters other than Lilith

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with Lilith

      Type: Passive, Familiar

      Item Pool: Devil Room, Greed Mode Devil Room

    * starting, black, red, eyes, wings, bat

  • Fate's Reward

    ItemID: 361

    "Your fate beside you"

    Quality: 2

    A familiar blue head that will follow Isaac and fire tears copying his tear damage

    This familiar is very similar to Incubus, however it only copies damage and is not affected by tears or range upgrades

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with ??? (Blue baby)

      Type: Passive, Familiar

      Item Pool: Item Room

    *, dead, blue, face, fates reward, fate reward

  • Lil Chest

    ItemID: 362

    "What's in the box?"

    Quality: 2

    A familiar chest that follows Isaac and has a 25% chance to drop a pickup after clearing a room

    Possible drops include hearts, coins, bombs, key, pills, card, runes, batteries, trinket

    There's a 10% chance to spawn a trinket

    UNLOCK: Unlock this item by beating Greed Mode with Isaac

      Type: Passive, Familiar

      Item Pool: Item Room, Greed Mode Item Room, Beggar

    * lil' chest, brown, orange, wooden

  • Sworn Protector

    ItemID: 363

    "Protective friend"

    Quality: 3

    An orbital angel which does 7 contact damage per tick and blocks shots

    The angel will attract bullets towards it and block them

    Sworn Protector will drop an eternal heart if it blocks 10 shots in one room. Can only happen once per room

    Visually this is almost identical to the Guardian Angel item, but without a face

    Counts as 1 of 3 angel items needed towards the Seraphim transformation

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with The Lost

      Type: Passive, Familiar

      Item Pool: Angel Room, Greed Mode Angel Room

    *, angel, wings, pink, white

  • Friend Zone

    ItemID: 364

    "Friendly fly"

    Quality: 1

    A white orbiting fly which deals 3 contact damage per tick to enemies

    This familiar orbits Isaac at a middle length distance somewhere between Distant Admiration and Forever Alone

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive, Familiar

      Item Pool: Item Room, Greed Mode Item Room, Key Beggar

    *, white, wings, grey, gray

  • Lost Fly

    ItemID: 365

    "Lost protector"

    Quality: 0

    A familiar fly that moves in a straight line and attaches itself to the first obstacle or wall it comes into contact with in each room.

    If any enemies walk into its path, it will deal 7 contact damage per tick

    If the obstacle it is attached to is destroyed then it will continue rolling in the direction it was previously travelling until it meets another wall or obstacle

      Type: Passive, Familiar

      Item Pool: Item Room, Greed Mode Item Room, Key Beggar

    *, white, wings, grey, gray

  • Scatter Bombs

    ItemID: 366

    "We put bombs in your bombs!"

    Quality: 1

    +5 bombs

    Causes your bombs to explode into 2-4 tiny bombs

    The smaller bombs deal half damage and have a smaller explosion area. They also retain most of your bomb synergizing items

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room, Bomb Beggar

    *, clear, transparent

  • Sticky Bombs

    ItemID: 367

    "Egg sack bombs!"

    Quality: 1

    +5 Bombs

    This item causes your bombs to stick to enemies

    When one of your bombs kills an enemy, a bunch of blue spiders are spawned to fight by your side, which deal x2 your current damage

      Type: Passive, Bomb Modifier

      Item Pool: Item Room, Greed Mode Item Room, Bomb Beggar, Bomb Beggar

    *, white, cobweb, web

  • Epiphora

    ItemID: 368

    "Intensifying tears"

    Quality: 1

    Shooting in one direction increases your fire rate until a cap is reached

    The maximum effect is to halve your delay, which takes roughly 10 seconds to achieve

    The accuracy of your tears is also reduced as your fire rate increases

    As soon as you change firing direction, your fire rate is reset to its normal amount

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, blue, drops, three, water

  • Continuum

    ItemID: 369

    "Transcendent tears"

    Quality: 2

    +3 Range Up

    +1.5 Tear Height

    Tears will now travel through walls and appear out of the opposite wall, similar to a portal-type mechanic

    Your tears can now also travel over rocks and objects in the environment

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, infinity, pink, purple, oo

  • Mr. Dolly

    ItemID: 370

    "Range + tears up"

    Quality: 3

    +0.7 Tears Up

    +5.25 Range Up

    +0.5 Tear Height

    Spawns 3 random types of hearts on the floor

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    *, pink, blonde, yellow, red, bow, baby mr dolly

  • Curse of The Tower

    ItemID: 371

    "You feel cursed..."

    Quality: 1

    Causes Isaac to spawn 6 troll bombs on the floor every time he gets hit, similar to the Anarchist Cookbook mechanic

      Type: Passive

      Item Pool: Item Room, Red Chest, Curse Room, Greed Mode Item Room

    *, blue, orange, poster, torn, paper, page, ripped

  • Charged Baby

    ItemID: 372

    "Bbbzzzzzt!"

    Quality: 3

    A familiar baby that has a random chance to drop a battery pickup or freeze all enemies in the room for a short while

    Charged Baby also has a chance to add one charge to your spacebar item

    These effects can only occur while in a hostile room with enemies

      Type: Passive, Familiar

      Item Pool: Shop, Greed Mode Shop

    *, yellow, grey, gray, power

  • Dead Eye

    ItemID: 373

    "Accuracy brings power!"

    Quality: 3

    Gives Isaac a +25% damage up for every tear that successfully hits an enemy

    The bonus from Dead Eye maxes out at double your damage (+100%)

    If a tear misses an enemy, there is a chance for the multiplier to be reset back to 1. It's a 20% chance on first miss, 33% for a second miss and 50% for anything beyond that

    Piercing shots work with this item and multiple hits with a single tear will each give a damage bonus

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, bullseye, target, grey, gray, black, red, circle

  • Holy Light!

    ItemID: 374

    "Holy shot!"

    Quality: 3

    Isaac has a random chance to fire a Holy tear, which when it hits an enemy, will spawn a light beam on the same enemy, dealing damage

    The beams from this item deal damage equal to 400% of your tear damage (4x damage multiplier for the beams only)

    The chance to fire a Holy tear is affected by your luck stat, maxing out at a 50% chance

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room, Angel Room

    *, glow, blue, white, black, ball

  • Host Hat

    ItemID: 375

    "Nice hat!"

    Quality: 3

    A familiar host that sits on Isaac's head and has a 20% chance to block enemy shots

    When a shot is blocked, Host Hat will fire 3 bullets back at the enemy

    Causes you to become immune to explosions.

    REPENTANCE - Host Hat no longer protects against stomps or shockwaves

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, skull, bone, grey, gray, zoidberg

  • Restock

    ItemID: 376

    "Never ending stores!"

    Quality: 3

    Causes your shops to instantly restock their items when you buy them

    REPENTANCE - Restock now exponentially increases the asking price with every shop purchase, and no longer spawns random pickups when the item is obtained

      Type: Passive

      Item Pool: Shop, Beggar

    *, recycle, green, arrows

  • Bursting Sack

    ItemID: 377

    "Spider love"

    Quality: 1

    Most spider enemies no longer target or deal contact damage to Isaac

    This is very similar to a Skatole for spiders instead of flies

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, egg, burst, pop, white, black

  • No. 2

    ItemID: 378

    "Uh oh..."

    Quality: 2

    Continuously firing or charging tears for 3 seconds causes Isaac to drop a Butt Bomb

    Only 1 Butt Bomb can be dropped per charge, so you'll need to stop firing then start again to drop another one

    Butt Bombs explode for 50 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time

    REPENTANCE - Added a visual fart cloud effect when spawning a No. 2 bomb

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, yfront, y-front, underpants, underwear, white, grey, gray, no 2, number two, number 2, no two

  • Pupula Duplex

    ItemID: 379

    "Wide shot"

    Quality: 2

    Transforms Isaac's tears into a wide arc shape which doubles their size and hitbox

    Gives Isaac spectral tears which allows them to travel through objects in the environment (i.e. rocks)

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, flat, white, grey, gray, blue, drip, water, eyes

  • Pay To Play

    ItemID: 380

    "Money talks"

    Quality: 2

    +5 coins

    This item turns all doors that require a key into doors which need a coin to enter instead

    This affects shops, item rooms, libraries and other key doors

      Type: Passive

      Item Pool: Shop, Greed Mode Item Room, Greed Mode Shop

    *, grey, gray, metal, slot, rectangle, silver

  • Eden's Blessing

    ItemID: 381

    "Your future shines brighter"

    Quality: 3

    +0.7 Tears Up

    Gives you a random item at the start of your next run (You need to start a fresh run to receive the item)

    Important progression items such as Key Pieces or the Mom's Shovel pieces cannot be given by Eden's Blessing

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with Eden

      Type: Passive

      Item Pool: Item Room

    *, white, rose, flower, petal

  • Friendly Ball

    ItemID: 382

    "Gotta fetch 'em all!"

    Quality: 1

    When used, can be thrown at enemies to capture them (similar to a Poké Ball)

    After capturing an enemy, the next use of the Friendly Ball will re-spawn the same enemy as a friendly companion which will attack other enemies

    The companion will persist between rooms and floors until it dies by taking enough damage

    REPENTANCE - Friendly Ball's charge time has been reduced to 2 (from 3). Walking over the thrown ball after capturing an enemy will immediately recharge it

      Type: Active

      Recharge Time: 2 rooms

      Item Pool: Item Room, Greed Mode Item Room

    *, pokemon, grey, gray, blue, deathstar, circle

  • Tear Detonator

    ItemID: 383

    "Remote tear detonation"

    Quality: 1

    When used, will detonate any tears currently on the screen and cause each one to split into 6 more tears which will fire in a circle, similar to Tammy's Head

    Luck-based items such as Holy Light are applied to each tear individually

    REPENTANCE - Tear Detonator is now a timed recharge (previously 1 room charge)

      Type: Active

      Recharge Time: 15 seconds

      Item Pool: Shop, Greed Mode Item Room

    *, blue, tnt, boom

  • Lil Gurdy

    ItemID: 384

    "A gurd of your own!"

    Quality: 1

    Gives Isaac a familiar Gurdy that will charge around the room dealing contact damage to enemies

    The Gurdy is charged by holding down the fire button and letting go. The longer the button is held the faster Gurdy will fling itself across the screen

    Lil Gurdy can glide over the top of objects and obstacles in the room

    At full charge Lil Gurdy deals 6 damage per tick while in contact with an enemy

    REPENTANCE - Lil Gurdy can deal significantly more damage (dependent on charge), and now bounces off of enemies and obstacles.

      Type: Passive, Familiar

      Item Pool: Item Room, Greed Mode Item Room

    *, pink, brown, circle, eye

  • Bumbo

    ItemID: 385

    "Bumbo want coin!"

    Quality: 1

    A beggar head which floats around the room and picks up any nearby coins. Every 6 coins Bumbo will evolve to a new form except for level 4 which takes 12 coins

    Level 2: Bumbo gains a body and crawls around the room, sometimes dropping random pickups

    Level 3: It now fires tears in the same direction Isaac does

    Level 4: Bumbo no longer fires tears but instead will chase enemies slowly and deal contact damage. It will also sometimes randomly drop bombs

    After reaching level 4 (and at a much lower chance before level 4), Bumbo will also continue to collect coins and drop random pickups, similar to the Bum Friend item, but can also drop pedestal items very rarely.

      Type: Passive, Familiar

      Item Pool: Item Room, Beggar

    *, pink, face, round, smile, :D

  • D12

    ItemID: 386

    "Rerolls rocks"

    Quality: 0

    When used, the D12 re-rolls any rocks into another random type of object (e.g. poop, pots, TNT, red poop, stone blocks etc.)

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with Cain

      Type: Active

      Recharge Time: 3 rooms

      Item Pool: Item Room, Greed Mode Shop

    * die, dice, pip, blue, 12, circle

  • Censer

    ItemID: 387

    "Peace be with you"

    Quality: 3

    Gives Isaac a familiar golden Censer which creates a huge aura of light that slows down any enemies inside it

    UNLOCK: Unlock this item by beating Greed Mode with Maggy

      Type: Passive, Familiar

      Item Pool: Angel Room, Greed Mode Angel Room

    *, gold, vase, cross

  • Key Bum

    ItemID: 388

    "He wants your keys!"

    Quality: 0

    A familiar beggar similar to Bum Friend that follows Isaac and collects keys, giving random chests in return

    Doesn't pick up golden keys

    Counts as 1 of 3 bum items needed towards the Super Bum transformation

    UNLOCK: Unlock this item by beating Greed Mode with Lazarus

      Type: Passive, Familiar

      Item Pool: Item Room, Secret Room, Key Beggar

    *, grey, gray, black, face, stone, rock, baby

  • Rune Bag

    ItemID: 389

    "Rune generator"

    Quality: 3

    A bag that follows Isaac and drops a random Rune or Soul Stone every 8 rooms

    REPENTANCE - Rune Bag now generates runes less frequently

    UNLOCK: Unlock this item by beating the Isaac boss with Lilith

      Type: Passive, Familiar

      Item Pool: Item Room, Secret Room

    *, purple, sack, pouch, pink

  • Seraphim

    ItemID: 390

    "Sworn friend"

    Quality: 3

    A familiar angel which follows Isaac and fires Sacred Heart tears which deal 10 damage at -25% shot speed and a reduced fire rate

      Type: Passive, Familiar

      Item Pool: Item Room, Angel Room, Greed Mode Angel Room

    *, angel, halo, wings, blue, white, baby

  • Betrayal

    ItemID: 391

    "Turn your enemy"

    Quality: 0

    Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac

    The effect will not trigger if there are less than 2 enemies in the room

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with Judas

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room, Devil Room, Greed Mode Devil Room

    *, red, silver, dagger, knife, bloody

  • Zodiac

    ItemID: 392

    "The heavens will change you"

    Quality: 1

    Zodiac will give you a random zodiac item effect that changes after every floor

    Possible item effects include: Taurus, Aries, Cancer, Leo, Virgo, Libra, Scorpio, Sagittarius, Capricorn, Aquarius, Gemini or Pisces

    UNLOCK: Unlock this item by beating Greed Mode with The Lost

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, cross, white, circle

  • Serpent's Kiss

    ItemID: 393

    "The kiss of death"

    Quality: 4

    Tears now have a random chance to apply a poison effect, dealing damage equal to your tears each tick, for 2 ticks

    Isaac now deals poison damage on contact with enemies similar to The Virus item (Damage over time 4 or 6 per tick)

    Enemies that were poisoned by contact damage have a 20% chance to drop a black sin heart when killed

    REPENTANCE - Serpent's Kiss no longer generates black hearts from the poison tears (the contact effect still can).

    UNLOCK: Unlock this item by beating Satan with Lilith

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, green, lips, kiss, drip, drop, serpents kiss, serpent kiss

  • Marked

    ItemID: 394

    "Directed tears"

    Quality: 0

    Isaac will now fire tears automatically directed at a red target on the ground which is controlled by the player

    This allows for a full 360 degree tear firing radius

    Can be overridden by other tear modifiers such as Mom's Knife or Brimstone

    +0.7 Tears Up

    +0.3 Tear Height

    +3.15 Range Up

    Has no effect with Lilith's Incubus

    REPENTANCE - Slight behaviour change, every time you leave the room this effect turns off until you press a shoot button again

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, red, cross, circle

  • Tech X

    ItemID: 395

    "Laser ring tears"

    Quality: 4

    Tears are replaced with the ability to charge and fire a laser ring that travels across the room

    The size of the ring will depend on how long you charge it

    The laser ring does damage equal to your normal tears rapidly to any enemies inside the ring

    Rings have infinite range and travel until they hit a wall

    REPENTANCE - Tech X damage now scales based on charge, from 25% at minimum to 100% at max

      Type: Passive, Tear modifier

      Item Pool: Item Room, Greed Mode Item Room

    * tech 10, tech ten, donut laser rings, vr, headset, visor

  • Ventricle Razor

    ItemID: 396

    "Short cutter"

    Quality: 1

    Allows you to create one brown tunnel and one blue tunnel in the floor, that can be used to teleport between wherever you placed each one

    This item will let you port out of the devil room but not back into it

    Very useful in the boss rush and challenge rooms

      Type: Active

      Recharge Time: Instant

      Item Pool: Shop

    *, scalpel, red, silver, white, grey, gray, metal, knife, cut

  • Tractor Beam

    ItemID: 397

    "Controlled tears"

    Quality: 2

    Isaac's tears now travel directly forwards following a beam of light, but will also move sideways based on your player movement

    +0.5 Tears Up

    +5.25 Range Up

    +0.16 Shot Speed Up

    +0.5 Tear Height

    Allows for more accurate correction when firing tears, as their direction can be controlled even after they have been fired

    If you switch the direction in which you are firing tears, the beam of light and all your tears will also be transported to the new direction

      Type: Passive, Tear Modifier

      Item Pool: Item Room, Greed Mode Item Room

    *, blue, glow, silver, grey, gray, light

  • God's Flesh

    ItemID: 398

    "Shrink shot!"

    Quality: 1

    Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size for 5 seconds and also run away from Isaac

    Shrunk enemies can be crushed and killed by walking over them

    Counts as 1 of 3 mushroom items needed towards the Fun Guy transformation

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, mushroom, pink, gods flesh, god flesh

  • Maw of The Void

    ItemID: 399

    "Consume thy enemy!"

    Quality: 4

    After firing tears for 3 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring which deals a lot of damage to any enemies inside it

    The ring deals damage equal to your tear damage rapidly to any enemies in contact with it, for a total of 30 ticks of damage

    You have to keep the fire button held down for the full 3 seconds to cause this effect

    Counts as 1 of 3 evil items needed towards the Leviathan transformation

    REPENTANCE - The damage up and black heart spawning mechanic was removed

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with Azazel

      Type: Passive

      Item Pool: Devil Room, Greed Mode Devil Room

    *, red, circle, blood, paint

  • Spear of Destiny

    ItemID: 400

    "Your destiny"

    Quality: 1

    In addition to tears, Isaac now holds a spear infront of him which deals damage equal to 2 times your tear damage

    The spear occasionally inflicts fear on enemies it damages.

    The spear cannot be thrown like Mom's Knife but deals damage while it is in contact with an enemy

      Type: Passive

      Item Pool: Angel Room, Greed Mode Angel Room

    *, grey, silver, sword, dagger, blade, knife

  • Explosivo

    ItemID: 401

    "Sticky bomb shot!"

    Quality: 1

    Tears now have a random chance to become sticky bombs, which will attach to enemies and explode after a few seconds

    The bomb explosion deals your tear damage + 60

    REPENTANCE - Explosivo tears now deal damage upon impact

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, orange, black, ball, circle, explode

  • Chaos

    ItemID: 402

    "!!!"

    Quality: 3

    When picked up, drops between 1-6 random pickups on the floor

    Causes all item pedestals to be chosen from a random item pool instead of the pre-defined ones which normally exist

    Fixed item drops won't be replaced - e.g. Cube of Meat after defeating a Horseman

    REPENTANCE - It is now possible to see items again that have been rerolled away, preventing emptying the item pool and 'Breakfasting'

    REPENTANCE - Chaos now assigns a "weight" to item pools based on how many items are in the pool. The more items in a pool, the more likely that pool will be picked

      Type: Passive

      Item Pool: Shop, Secret Room

    *, red, cross

  • Spider Mod

    ItemID: 403

    "Mod buddy!"

    Quality: 1

    A familiar grey spider that wanders around and allows you to see your tear damage and the health bars of all enemies

    The spider will inflict a random status effect on any enemies it comes into contact with (e.g. slow, shrink, fear)

    Spider Mod will also randomly drop battery consumables or blue spiders when a room is completed

    For the sake of simplicity for players, all damage values displayed are multiplied by 10 and rounded to the nearest number

    This item is a reference to Spider853, creator of Spidermod for the original game and one of the lead developers that worked on Rebirth and its DLCs

      Type: Passive

      Item Pool: Shop, Greed Mode Shop

    *, robot, red, grey, gray, silver, metal, antenna

  • Farting Baby

    ItemID: 404

    "He farts!"

    Quality: 1

    A familiar that follows Isaac and blocks tears

    If a tear hits Farting Baby, there is a 10% chance for it to fart, with 3 possible effects: Charm, Poison or Knock back

    Charm deals 5 damage. Poison deals 5 damage initially and then 3.5

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with Isaac

      Type: Passive, Familiar

      Item Pool: Item Room

    * fart baby, green, fat

  • GB Bug

    ItemID: 405

    "Game breaking bug, right away!"

    Quality: 0

    REPENTANCE - GB Bug is now a thrown projectile, activated by double tapping an attack button. It rerolls enemies and pickups it comes into contact with, then despawns. It returns after a room has been cleared

    UNLOCK: Unlock this item by beating Greed Mode with Eden

      Type: Passive

      Item Pool: Item Room, Secret Room, Greed Mode Shop

    *, red, yellow, green, white, square, rectangle

  • D8

    ItemID: 406

    "Reroll stats"

    Quality: 2

    When used, the D8 rerolls all of your stats

    Will only effect your damage, tears, range and speed stats

    Each stat is given a multiplier that applies after all other adjustments

    UNLOCK: Unlock this item by beating Challenge #28 (Pride Day)

      Type: Active

      Recharge Time: 4 Rooms

      Item Pool: Item Room, Greed Mode Shop

    * dice, pip, die, black, grey, gray, pyramid, triangle

  • Purity

    ItemID: 407

    "Aura stat boost"

    Quality: 2

    Purity will boost one of Isaac's stats depending on the colour of the aura around him

    When you take damage, the aura will be removed and replaced with another random one when you enter the next room

    Colour code is as follows:

    Red = +4.0 Damage

    Blue = -4 Tear Delay

    Yellow = +0.5 Speed Up

    Orange = +7.5 Range Up, +1.0 Tear Height

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with Maggy

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room, Greed Mode Angel Room

    *, white, flower, lotus, petal, rose

  • Athame

    ItemID: 408

    "Call to the void"

    Quality: 2

    Now when you take damage, a black ring will appear around Isaac that damages any enemies in contact with it

    The ring damage scales with your tear damage

    REPENTANCE - No longer has a chance to drop black hearts

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with Eve

      Type: Passive

      Item Pool: Devil Room, Curse Room, Greed Mode Devil Room

    *, grey, gray, silver, metal grabber, hand, robot

  • Empty Vessel

    ItemID: 409

    "I reward an empty vessel"

    Quality: 2

    +2 Black Hearts

    When Isaac has no red hearts, this item gives Isaac the ability to fly. Every 40 seconds spent in the same room since last activating, when the timer displays 00, 20 or 40 seconds, a shield triggers, nullifying all types of damage for 10 seconds

    As soon as Isaac has half a red heart or more, this item deactivates

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with Lazarus

      Type: Passive

      Item Pool: Devil Room, Demon Beggar

    *, red, grey, gray, black, bomb

  • Evil Eye

    ItemID: 410

    "Eye shot!"

    Quality: 2

    While firing tears this item gives you a chance to fire an eye across the screen with a very slow shot speed, which will fire tears of its own in the same direction as Isaac

    The evil eye shots will be destroyed if they come into contact with enemies or obstacles

    UNLOCK: Unlock this item by beating Greed Mode with Cain

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, blue, glow, circle

  • Lusty Blood

    ItemID: 411

    "Their blood brings rage!"

    Quality: 3

    Each time Isaac kills an enemy, you get a temporary +0.5 damage up which lasts for the current room

    Each subsequent kill will stack further damage up to a maximum of +5 Damage Up after 10 kills

    This item is the same principle as the Bloody Lust item from the original flash game

    REPENTANCE - Added to the Devil Room pool

    UNLOCK: Unlock this item by beating Greed Mode with Samson

      Type: Passive

      Item Pool: Item Room, Devil Room, Greed Mode Item Room

    *, red, heart, bleed, bloody

  • Cambion Conception

    ItemID: 412

    "Feed them hate"

    Quality: 2

    After taking enough damage you will gain a permanent demon familiar

    Possible familiars include: Dark Bum, Demon Baby, Leech, Lil' Brimstone, Succubus, Incubus

    The effect is shown visually in 3 stages with the character's belly getting larger each time until it finally gives birth to a familiar.

    The first and second familiars spawn after 15 hits, then 30 hits for the third and fourth

    Cambion Conception cannot grant more than 4 familiars in total

    Lilith starts with this item

    UNLOCK: Unlock this item by beating ??? with Lilith

      Type: Passive

      Item Pool: Devil Room, Greed Mode Devil Room

    *, red, organ, lung, starting

  • Immaculate Conception

    ItemID: 413

    "Feed them love"

    Quality: 1

    After picking up 15 hearts, Isaac gains a permanent angelic familiar and a soul heart drops

    Possible familiars include: Holy Water, Guardian Angel, Sworn Protector, The Relic and Seraphim

    It is possible to get multiple followers by continuing to pick up hearts, at intervals of 15 hearts each

    After all 5 familiars have spawned, it will just drop a soul heart every 15 hearts collected

    UNLOCK: Unlock this item by beating Boss Rush with Lilith

      Type: Passive

      Item Pool: Angel Room, Greed Mode Angel Room

    *, white, halo

  • More Options

    ItemID: 414

    "There are even more options!"

    Quality: 3

    Two items now spawn in each of your item rooms, however only one can be taken and the other will disappear

    Doesn't work for half-sized item rooms

      Type: Passive

      Item Pool: Shop

    *, orange, question, mark, gold, ?

  • Crown of Light

    ItemID: 415

    "The untainted gain power"

    Quality: 4

    +2 Soul Hearts

    A crown that replaces normal tears with blue diamond tears while you don't have any empty red heart containers or bone hearts

    While the effect is active, tears do double damage, +5.25 Range Up, +0.5 Tear Height and -0.30 Shot Speed

    The crown will glow blue while active, if inactive it will appear grey

    The effect will also deactivate for the rest of the current room when you take damage, regardless of your health

      Type: Passive

      Item Pool: Angel Room, Greed Mode Angel Room

    *, blue, glow

  • Deep Pockets

    ItemID: 416

    "More stuff to carry!"

    Quality: 2

    Increases your money cap to 999

    When a room clear would otherwise yield no rewards, it now spawns 1-3 pennies

    REPENTANCE - Deep Pockets no longer adds a pill/card slot, instead increases money cap to 999

    UNLOCK: Unlock this item by beating The Chest floor with Keeper

      Type: Passive

      Item Pool: Shop, Greed Mode Item Room, Greed Mode Shop

    *, grey, gray, bag, stone, rock

  • Succubus

    ItemID: 417

    "Damage booster"

    Quality: 3

    A flying familiar that bounces around the room with a damaging aura, dealing rapid damage to any enemies inside it and boosting Isaac's tear damage

    While standing in the black aura, Isaac has a temporary 1.5x damage multiplier (this will stack if you have more than one Succubus)

    The aura deals 30% of your tear damage to enemies per tick

    UNLOCK: Unlock this item by beating The Lamb with Lilith

      Type: Passive, Familiar

      Item Pool: Devil Room, Demon Beggar

    *, black, red, wings, grey, gray

  • Fruit Cake

    ItemID: 418

    "Rainbow effects!"

    Quality: 2

    Gives you a different tear effect with every tear that you fire

    Tear effects include: Anti-Gravity, GodHead, Proptosis, Tiny Planet, Holy Light, Soy Milk, Cricket's Body, Explosivo, Continuum, My Reflection, Ring Worm, Hook Worm, Wiggle Worm, Flat Worm

    With Dr. Fetus, this item will also cycle through random Bomb Modifiers (e.g. Butt Bombs, Hot Bombs)

      Type: Passive, Tear Modifier

      Item Pool: Item Room

    *, brown, red, green, orange, pile, dirt

  • Teleport 2.0

    ItemID: 419

    "I-teleport!"

    Quality: 2

    When used will teleport you to another random room that has not been explored yet

    After all the normal rooms have been explored, the hierarchy of rooms chosen is: Super Secret Room, Shop, Item Room, Sacrifice Room, Dice Room, Library, Curse Room, Miniboss, Challenge Room, Bedroom, Arcade, Vault, Secret Room, Devil/Angel Room, I AM ERROR

    This ordering means a Devil and I Am Error room can both be forced if all others have been visited

    If used in a normal room with enemies it will teleport you out and back into the exact same room

      Type: Active

      Recharge Time: 4 rooms

      Item Pool: Item Room

    *, golden, yellow, robot, antenna, black, teleport two, teleport 20

  • Black Powder

    ItemID: 420

    "Spin the black circle!"

    Quality: 1

    Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it

    The trail of black powder left on the floor will quickly disappear, meaning you are limited on the size of the pentagram symbol you can create

    REPENTANCE - Black Powder's pentagram can now damage flying enemies

      Type: Passive

      Item Pool: Devil Room, Demon Beggar

    *, black, grey, gray, bag, sack, pouch

  • Kidney Bean

    ItemID: 421

    "Love toots!"

    Quality: 0

    When used, applies the charm effect to any enemies in close range and deals 5 damage

    Charmed enemies will prioritize attacking other enemies in the room, otherwise they will still attack Isaac

    REPENTANCE - Kidney Bean now has a bigger effect radius, no longer deals damage to the enemies it's charming, and charge time has been reduced to 1 (from 2).

      Type: Active

      Recharge time: 1 Rooms

      Item Pool: Item Room, Greed Mode Item Room

    *, red

  • Glowing Hour Glass

    ItemID: 422

    "Turn back time"

    Quality: 1

    When used, this item will rewind time and put you back in the previous room, in the same state you were in at that moment

    This means any damage taken or consumables used in the current room will be reset back to the previous state

    Can be used to check the contents of an Item Room without affecting Planetarium spawn chances

      Type: Active

      Recharge time: 3 rooms

      Item Pool: Item Room, Shop

    * hourglass, hour glass, egg, timer, blue, brown Glowing Hourglass

  • Circle of Protection

    ItemID: 423

    "Protect me from myself"

    Quality: 1

    Gives Isaac a large white halo around him, that deals a bit of damage to any enemies in contact with the ring

    Every time an enemy bullet enters the ring, there is a chance it will reflect a homing tear back at the enemy

      Type: Passive

      Item Pool: Angel Room, Greed Mode Angel Room

    *, white, bandana, circle, bandage

  • Sack Head

    ItemID: 424

    "More sacks!"

    Quality: 3

    Coins have a 10% chance to be replaced with Sack. Bombs, keys, cards, runes and batteries have a 20% chance

    Spawns a sack when picked up

    Can lead to game-breaking combinations with the D20 due to the amount of consumables and batteries spawned by the item sacks

    REPENTANCE - Added to the Secret Room pool

      Type: Passive

      Item Pool: Shop, Secret Room

    *, bag, grey, cry, blue, tear, shia paper bag sackhead

  • Night Light

    ItemID: 425

    "Scared of the dark?"

    Quality: 2

    Gives Isaac a cone of light infront of him that slows any enemies inside it and their tears

    The light faces the direction that you are facing, not the direction you are firing

    Removes Curse of Darkness for the current floor, if picked up on a floor where the curse is active

      Type: Passive

      Item Pool: Shop, Greed Mode Item Room

    * Shop, Greed Mode Item Room, white, blue, inhaler

  • Obsessed Fan

    ItemID: 426

    "Follows my every move...""

    Quality: 0

    A purple familiar fly that follows your exact movement on a 1 second delay and deals 2 contact damage to enemies

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive, Familiar

      Item Pool: Item Room, Key Beggar

    *, purple, fly

  • Mine Crafter

    ItemID: 427

    "Booom!"

    Quality: 1

    When used, places an explosive TNT barrel next to you

    The TNT barrel can be pushed and used to explode rocks or damage enemies

    If used a second time in the same room while the last TNT barrel is still there, it will remotely explode the first TNT and not spawn another

      Type: Active

      Recharge time: 1 room

      Item Pool: Item Room

    *, orange, brown

  • PJs

    ItemID: 428

    "You feel cozy"

    Quality: 2

    +4 Soul Hearts

    Fully restores your red health

    REPENTANCE - Added to the Gold Chest Pool

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    *, blue, baby, grow, headless, golden chest pool, gold chest pool,

  • Head of the Keeper

    ItemID: 429

    "Penny tears!"

    Quality: 2

    Isaac's tears become coins and now have a 5% chance to drop pennies on the floor upon successfully hitting an enemy

    Has a chance to drop when exploding a dead shopkeeper

      Type: Passive

      Item Pool: Dead shopkeeper

    *, gold, eyes, grey, gray

  • Papa Fly

    ItemID: 430

    "Turret follower"

    Quality: 1

    A familiar blue fly that will follow Isaac's movement pattern but delayed by 1 second

    Papa Fly will fire tears at nearby enemies that deal damage equal to Isaac's tear damage

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Passive, Familiar

      Item Pool: Item Room, Key Beggar

    *, blue

  • Multidimensional Baby

    ItemID: 431

    "ydduB Buddy"

    Quality: 1

    A familiar baby that will follow your movement pattern on a 2 second delay

    Tears that pass through the baby will double up and gain x1.33 speed boost, +4.0 tear height

      Type: Passive, Familiar

      Item Pool: Item Room, Greed Mode Item Room, Devil Room, Greed Mode Devil Room

    *, grey, gray, black, ghost

  • Glitter Bombs

    ItemID: 432

    "Prize bombs!"

    Quality: 2

    +5 bombs

    Isaac's normal bombs become pink and causes them to drop random pickups when they explode (e.g. keys, coins, bombs, trinkets)

    Bombs have a chance to charm enemies

      Type: Passive, Bomb Modifier

      Item Pool: Item Room, Bomb Beggar

    *, pink, sparkle

  • My Shadow

    ItemID: 433

    "Me! And my shaaaadow!"

    Quality: 0

    Each time you take damage, My Shadow will apply a fear effect to all enemies in the room and spawn a familiar black charger that will attack for you

    The charger deals 5 damage, and will be killed if it is hurt too much

    UNLOCK: Unlock this item by beating Greed Mode with Judas

      Type: Passive

      Item Pool: Devil Room, Greed Mode Devil Room

    *, black, outline, upside, down

  • Jar of Flies

    ItemID: 434

    "Gotta catch 'em all?"

    Quality: 2

    Every time you kill an enemy a fly will be added to the Jar, allowing you to stack up to 20

    Using the Jar of Flies will release all the flies that are currently in the jar as friendly flies that will damage enemies

    Counts as 1 of 3 fly items needed towards the Beelzebub transformation

      Type: Active

      Recharge time: Instant

      Item Pool: Shop, Greed Mode Item Room, Greed Mode Shop

    *, glass, bottle

  • Lil Loki

    ItemID: 435

    "4-way buddy!"

    Quality: 1

    A Loki familiar that follows Isaac and shoots tears 4 tears in a cross pattern, dealing a flat 3.5 damage each

      Type: Passive

      Item Pool: Item Room

    *, red, devil, baby, face

  • Milk!

    ItemID: 436

    "Dont cry over it..."

    Quality: 1

    Gives Isaac a familiar glass of milk that follows him and spills on the floor upon taking damage

    After being spilt, the milk gives you a -2 Tear Delay (Tears up) for the rest of the room

      Type: Passive, Familiar

      Item Pool: Item Room, Greed Mode Item Room

    *, glass, white, cup

  • D7

    ItemID: 437

    "Reroll rewards!"

    Quality: 1

    When used, the D7 will restart the current room and bring back all enemies once again, enabling you to farm rewards that spawn at the end after beating the room

    Can be used to generate infinite consumable combinations, gaining as many coins/keys/bombs as you need

    Will teleport you to out of the room if used in a Boss Room or Devil Room

    If used in a greed fight it can be used to reroll the room into a Shop

      Type: Active

      Recharge time: 3 rooms

      Item Pool: Item Room

    * dice, pip, die, turban, white, grey, gray

  • Binky

    ItemID: 438

    "Memories..."

    Quality: 3

    +1 Soul heart

    +0.75 Tears Up

    Isaac size down

    Makes Isaac very small like a baby, reducing his hitbox size

      Type: Passive

      Item Pool: Boss Room, Gold/Stone Chest

    * pacifier, dummy, baby, blue, white

  • Mom's Box

    ItemID: 439

    "What's inside?"

    Quality: 3

    When used, Mom's Box will drop a random trinket on the ground

    +1 Luck while held

    While held, doubles the effect of trinkets which make sense to be doubled (e.g. +4 damage from Curved Horn instead of 2, -4 Tear Delay from Cancer instead of 2)

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Shop, Greed Mode Shop

    *, black, purple, mom box, moms box

  • Kidney Stone

    ItemID: 440

    "Matt's kidney stone"

    Quality: 1

    Randomly while firing tears, Isaac will stop firing and turn red, where he will charge and release a lot of 'tears' in one go. In the burst of tears is a kidney stone which deals a lot of damage

    -17 Range Down

    +2.0 Tear height

    REPENTANCE - Kidney Stone is no longer a speed downgrade

    UNLOCK: Unlock this item by beating Challenge #29 (Onan's Streak)

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, bloody, brown, hair, wig, scalp

  • Mega Blast

    ItemID: 441

    "Laser breath"

    Quality: 4

    Upon use, fires a huge Mega Satan laser for 15 seconds, dealing your tear damage * 5 per tick to anything in its path and pushing Isaac back by the force

    The laser persists for the entire 15 seconds even between rooms and floors

    This item appears in the Devil Room but is weighted to be about 5 times rarer than all other devil room items

    UNLOCK: Unlock this item by beating Mega Satan with every character

      Type: Active

      Recharge time: 12 rooms

      Item Pool: Devil Room, Greed Mode Devil Room

    *, red, grey, gray, brown, black, red, eyes

  • Afterbirth Plus Items (110)

  • Dark Prince's Crown

    ItemID: 442

    "Loss is power"

    Quality: 1

    A crown appears above your head and while at exactly 1 full red heart of health, you gain a +1.5 Range Up, +2.0 Tears Up and +0.20 Shot Speed Up

    Any time your health changes to be not exactly 1 red heart you lose the effect

    This item does nothing with The Lost

    REPENTANCE - Dark Prince's Crown now grants more of an increase in rate of fire, and the bonus now breaks the soft tears cap.

    UNLOCK: Unlock this item by defeating Delirium as Azazel

      Type: Passive

      Item Pool: Devil Room, Curse Room

    *, red, glow, Dark Prince's Crown, dark princes crown, dark prince crown

  • Apple!

    ItemID: 443

    "Trick or treat?"

    Quality: 3

    Gives you a 6.66% chance to fire a razor blade which deals x4 damage

    +0.3 Tears Up

    This item also turns your tears red, but does not change your actual damage stat or the damage your normal tears do

    The chance to fire a razor blade depends on your luck stat, and at +14 luck you will fire a razor blade every time

      Type: Passive

      Item Pool: Item Room

    *, red,

  • Lead Pencil

    ItemID: 444

    "Hes a bleeder!"

    Quality: 3

    With every 15 tears fired, Isaac will fire a cluster of 12 tears instead of your normal tear

    Causes your normal tears to fire out of one eye, which means tears will fire in a near-perfect line instead of slightly off-center

    REPENTANCE - Lead Pencil's tear barrage no longer deals double damage

      Type: Passive

      Item Pool: Item Room, Gold/Stone Chest

    *, yellow, pen

  • Dog Tooth

    ItemID: 445

    "Bark at the moon!"

    Quality: 1

    +0.3 Damage Up

    +0.1 Speed Up

    When entering a room connected to a Secret Room or Super Secret Room, a howling sound will play

    When entering a room with a crawl space trapdoor in it, a barking sound will play

      Type: Passive

      Item Pool: Item Room

    *, white, silver

  • Dead Tooth

    ItemID: 446

    "Halitosis"

    Quality: 1

    While firing, you gain a green aura that poisons any enemies which touch it. The poison deals your tear damage per tick, for 2 ticks

    Has no effect on Lilith, as she cannot fire tears

      Type: Passive

      Item Pool: Item Room

    *, grey, gray, brown, face, rabbit

  • Linger Bean

    ItemID: 447

    "Crying makes me toot"

    Quality: 0

    While firing tears constantly for 7.5 seconds, you spawn a poop cloud, which deals periodic damage to any enemies which come near it

    The cloud deals damage equal to your base tear damage per tick, roughly 5 times per second

    Clouds last 15 seconds before disappearing

    The cloud can be pushed slightly by firing tears at it

      Type: Passive

      Item Pool: Item Room, Beggar

    *, pink

  • Shard of Glass

    ItemID: 448

    "Blood and guts!"

    Quality: 0

    Upon taking damage, Isaac starts to bleed, leaving a trail of blood andspraying blood tears everywhere which deal damage to nearby enemies

    While bleeding, Isaac takes damage every 30 seconds

    The blood sprays in the direction you are current firing, or just randomly near Isaac if not shooting your tears

    The blood spray scales with your current tear damage and any future damage increases

    This effect lasts until you pick up a red heart

    Upon taking damage, this item gives a 25% chance to drop a full red heart

    REPENTANCE - This entire item has been reworked

      Type: Passive

      Item Pool: Item Room

    *, blue, triangle, pyramid

  • Metal Plate

    ItemID: 449

    "It itches..."

    Quality: 1

    +1 Soul Heart

    Enemy bullets have a 25% chance to be deflected back at the enemy, which will hurt them and apply the concussive status effect, causing it to be stunned for a few seconds

      Type: Passive

      Item Pool: Item Room

    *, silver, metal, grey, gray

  • Eye of Greed

    ItemID: 450

    "Gold tears!"

    Quality: 2

    Every 20th tear fired will also fire a golden coin tear at the same time. This tear turns enemies to gold for a few seconds and causes them to drop 1-4 coins if killed while golden (similar to the Midas' Touch item)

    When the Midas Touch tear effect triggers, it will remove 1 coin from your current total

    The golden tear deals double your tear damage

    The effect can still trigger even if you have no held coins

    UNLOCK: Unlock this item by defeating Greedier Mode with Keeper

      Type: Passive

      Item Pool: Secret Room

    *, cent, coin, silver, metal, grey, gray

  • Tarot Cloth

    ItemID: 451

    "I see the future"

    Quality: 3

    Drops a random card on pickup

    Doubles the effect of most tarot cards

    For some cards this does not double the effect (e.g. Stars card only teleports you once). In general if a card has a number of things, that thing is doubled

    REPENTANCE - Now only works with cards, not Runes. Added a slow pulsing outline HUD effect for cards that would be buffed by Tarot Cloth

      Type: Passive

      Item Pool: Shop, Curse Room

    *, purple, grey, bag

  • Varicose Veins

    ItemID: 452

    "I'm leaking..."

    Quality: 2

    Every time you take damage, 10 high damage tears are fired in a circle around you (similar to the Tammy's Head effect)

    Tear damage is equal to Isaac's tear damage + 25 flat damage

    Additionally, has a chance to activate the Anemic effect when taking damage for 2 seconds

    Similar to Tammy's Head, this item synergizes with a lot of items (i.e. with Brimstone it fires 10 lasers)

      Type: Passive

      Item Pool: Item Room

    *, red, tube

  • Compound Fracture

    ItemID: 453

    "Bone tears!"

    Quality: 2

    Turns your tears into bones, which shatter into 1-3 smaller bone shards upon hitting any object or enemy

    The smaller bone shards deal damage equal to half your normal tear damage

    +1.5 Range Up

    +1.0 Tear Height

    UNLOCK: Unlock this item by defeating Delirium in The Void floor with Lazarus

      Type: Passive

      Item Pool: Item Room

    *, bone, broken, snapped, white, bloody

  • Polydactyly

    ItemID: 454

    "Hold me!"

    Quality: 2

    Allows Isaac to carry two cards, runes or pills (or any combination of these) at the same time

    Drops a random card, pill or rune on pickup

      Type: Passive

      Item Pool: Item Room

    *, pink

  • Dad's Lost Coin

    ItemID: 455

    "I remember this..."

    Quality: 2

    +1.5 Range Up

    Drops a lucky penny

    UNLOCK: Unlock this item by beating Greedier Mode with The Lost

      Type: Passive

      Item Pool: Boss Room, Beggar, Gold/Stone Chest

    *, silver, metal, grey, gray, omega, dads lost coin, dad lost coin, dad coin

  • Midnight Snack

    ItemID: 456

    "HP up"

    Quality: 1

    +1 HP Up

    REPENTANCE - This was renamed from Moldy Bread

      Type: Passive

      Item Pool: Boss Room, Beggar, Gold/Stone Chest

    *, sandwich, toast, brown, green, bite, bitten

  • Cone Head

    ItemID: 457

    "Hard headed!"

    Quality: 2

    +1 Soul Heart

    Each time you take damage from any source, Cone Head has a 20% chance to prevent it from reducing your health

    Isaac flashes blue very briefly when damage is negated by this item

      Type: Passive

      Item Pool: Item Room

    * northernlion, nl, northern lion, ryan letourneau, egg, egg father, egg daddy, dad, BALD, northernlion's head resembles an egg much like this item, isn't that hilarious?, pink

  • Belly Button

    ItemID: 458

    "Whats in there?"

    Quality: 3

    Drops one random trinket on pickup

    Gives you an extra trinket slot

      Type: Passive

      Item Pool: Item Room

    *, pink, circle, cross

  • Sinus Infection

    ItemID: 459

    "Booger tears!"

    Quality: 3

    Isaac's tears have a random chance to be a booger instead, which stick on to enemies and deal periodic poison damage until they die

    Each tick of poison damage is equal to your normal tear damage

    Each booger persists until the enemy is dead or 60 seconds has passed

      Type: Passive

      Item Pool: Item Room

    * bogey, boger, green, drop, drip, boogey,

  • Glaucoma

    ItemID: 460

    "Blind tears!"

    Quality: 2

    Adds a chance to shoot a concussive tear, which will cause enemies to walk around dazed in confusion

    The daze effect is effectively permanent for normal enemies, and has a much longer duration for bosses compared to other status effects

    Makes all rooms slightly darker

    The visual effect of a Glaucoma tear is hard to notice, however it is slightly lighter than normal tears and is not a perfect circle shape

      Type: Passive

      Item Pool: Item Room

    *, white, circle, eye, circle

  • Parasitoid

    ItemID: 461

    "Egg tears!"

    Quality: 3

    This item gives you a chance that instead of firing tears you will fire an egg sack, which slows enemies on hit and drops a pool of white slowing creep below them

    If a parasitoid shot successfully hits an enemy, a blue friendly fly or spider is spawned

      Type: Passive

      Item Pool: Item Room

    *, blue, fly

  • Eye of Belial

    ItemID: 462

    "Possessed tears!"

    Quality: 3

    Causes your tears to become piercing, allowing them to travel through enemies

    After hitting its first enemy, each tear will double in damage and gain a homing effect

    +1.5 Range Up

    +1.0 Tear Height

    UNLOCK: Unlock this item by defeating Greedier Mode with Judas

      Type: Passive

      Item Pool: Devil Room

    *, red, circle

  • Sulfuric Acid

    ItemID: 463

    "Acid tears!"

    Quality: 2

    +0.3 Damage Up

    Each tear has a chance to become acidic, allowing it to break rocks, pots and other breakable objects

    Acidic tears can also be used to open secret rooms

      Type: Passive

      Item Pool: Item Room

    *, orange, yellow, bottle, X

  • Glyph of Balance

    ItemID: 464

    "A gift from above"

    Quality: 1

    +2 Soul Hearts

    This item will modify drops from room clearing and champion enemies based on your current player state. The priority list of what will drop from champion enemies in order is as follows:

    Soul Hearts - When you have no red heart containers and less than 2 soul hearts

    Red Hearts (Full hearts) - While at 0.5 red hearts

    Keys - When you have no keys

    Bombs - When you have no Bombs

    Red Hearts (Full hearts) - When you have at least half a red heart container empty

    Coins - While at less than 15 cents

    Keys - When you have less than 5 keys

    Bombs - When you have less than 5 bombs

    Trinkets - If you have no trinkets and there are no trinkets on the ground in the room

    Soul Hearts - When you have less than 6 total heart containers of any kind

    If none of the above conditions are true, champions will resume dropping their regular pickups

    REPENTANCE - Glyph of Balance now also modifies room clear rewards

    UNLOCK: Unlock this item by defeating Greedier mode with Maggy

      Type: Passive

      Item Pool: Angel Room

    *, blue, triangle

  • Analog Stick

    ItemID: 465

    "360 tears!"

    Quality: 2

    +0.35 Tears Up

    Allows you to fire tears diagonally by holding down two of the fire buttons at once

    If you are using a gamepad, this item allows you to fire in any direction

      Type: Passive

      Item Pool: Item Room

    *, grey, gray, mushroom

  • Contagion

    ItemID: 466

    "Outbreak!"

    Quality: 2

    The first enemy you kill in each new room will now explode and poison all nearby enemies, causing them to take periodic damage until they also die and explode

    If you have lots of enemies near each other this can cause a chain reaction, killing lots of enemies in one go

      Type: Passive

      Item Pool: Item Room

    *, red, glow, biological, danger

  • Finger!

    ItemID: 467

    "Watch where you point that!"

    Quality: 1

    Gives Isaac a finger which floats infront of him and points in the same direction he is facing or firing. The finger deals 10% of your normal damage to all enemies in the same direction that the finger is pointing

    The finger will also deal damage to entities such as fires and poops

    Applies on-hit status effects such as the burning debuff from Fire Mind

    Spawns guppy flies if you have the Guppy transformation

      Type: Passive, Familiar

      Item Pool: Item Room

    *, thumb, toe, pink, bone

  • Shade

    ItemID: 468

    "It follows"

    Quality: 0

    Isaac gains a shadow familiar that will follow Isaac's movement pattern delayed by 1 second and deal 2 contact damage to enemies per tick

    Shade is absorbed by Isaac after dealing 600 damage. This spawns friendly charger enemies and causes Isaac to deal 2 contact damage (same as the shade did). This effect stacks with multiple shades, scaling the contact damage each time

    UNLOCK: Unlock this item by defeating Delirium in The Void floor with Judas

      Type: Passive, Familiar

      Item Pool: Devil Room, Curse Room

    *, blue, white, eyes

  • Depression

    ItemID: 469

    ":("

    Quality: 1

    Isaac gains a cloud familiar that follows him and leaves a trail of tears on the floor which damages enemies for 2 damage per tick

    Enemies touching the cloud have a chance to activate the Crack the Sky effect, which spawns a light beam that deals damage equal to your tear damage + 20

      Type: Passive, Familiar

      Item Pool: Item Room

    *, pink, purple, cloud, smoke

  • Hushy

    ItemID: 470

    "Lil hush!"

    Quality: 0

    Gives Isaac a small Hush familiar that bounces diagonally around the room dealing 2 contact damage per tick

    While you're firing tears Hushy will stop moving, which allows you to keep it in one place

    Hushy will block enemy tears and projectiles

    UNLOCK: Unlock this item by beating Hush with Apollyon

      Type: Passive, Familiar

      Item Pool: Item Room

    *, blue, pacman, ghost, face

  • Lil Monstro

    ItemID: 471

    "Ain't he cute?"

    Quality: 2

    Gives Isaac a small Monstro familar, who's tears can be charged and released in a shotgun style effect, much like Monstro's main attack

    Lil Mosntro's tears each deal base damage (3.5) and does not scale with damage upgrades

      Type: Passive, Familiar

      Item Pool: Item Room

    *, head, cleft, lip, palate, hairlip, tooth

  • King Baby

    ItemID: 472

    "Lord of the dead!"

    Quality: 0

    A baby familiar that follows you and causes other familiars to follow it. It stops moving while Isaac is firing tears and upon releasing the fire button, King Baby will teleport back to your location

    King Baby will always appear first in the queue of familiars

    REPENTANCE - Familiars now automatically aim at enemies when being commanded by King Baby

    UNLOCK: Unlock this item by beating Delirium on The Void floor with ???

      Type: Passive, Familiar

      Item Pool: Shop

    *, blue, crown, gold, yellow

  • Big Chubby

    ItemID: 473

    "Chub chub"

    Quality: 1

    A familiar that follows Isaac and charges forwards very slowly, dealing 2.7 damage per tick to any enemies it comes into contact with

    Almost identical to the Little Chubby familiar, but this one moves much more slowly and deals less damage

    REPENTANCE - The damage tick rate on Big Chubby has been increased

      Type: Passive, Familiar

      Item Pool: Item Room

    *, face, yellow, brown

  • Plan C

    ItemID: 475

    "Use with caution"

    Quality: 0

    Upon use, this item deals 9,999,999 damage to all enemies in the room and then kills you 3 seconds later

    This is a single use active item, meaning it is destroyed after using it

    Does not kill both phases of multi-phase bosses like Hush or Ultra Greed

    If used to kill a boss, the kill still counts as a victory for post-it note completion marks, but the run will still get a game over

    Delirium's death animation takes longer than 3 seconds, meaning you will die before it can count as a completion mark. One exception to this is if you are playing as Lazarus or have Lazarus' Rags - you will respawn in the same room and get the kill

    Plan C is 5 times rarer than other items in the same item pool, making it less likely to appear

    UNLOCK: Unlock this item by defeating Greedier Mode with Lazarus

      Type: Active

      Recharge time: One time use

      Item Pool: Shop, Devil Room, Curse Room, Red Chest, Demon Beggar

    *, red, pill, medicine, drug

  • D1

    ItemID: 476

    "What will it be?"

    Quality: 2

    When used, the D1 duplicates 1 random pickup in the current room, including cards, runes, chests and trinkets

    If you drop your current card, rune or pill and duplicate it, this item can effectively act similar to the Blank Card and Placebo items

    Jera runes cannot be duplicated using the D1

    Duplicated chests can turn into another kind of chest randomly (e.g. Red chests)

    Can be used in a shop to duplicate pickups which have not yet been purchased, and take the duplicate pickup for free

    UNLOCK: Unlock this item by defeating Greedier Mode with Isaac

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Item Room

    *, white, grey, gray, dice pip, one

  • Void

    ItemID: 477

    "Consume"

    Quality: 4

    When used, Void will consume any pedestal items in the current room

    If an active item is consumed, its effect will be added to Void's effect when used, allowing you to consume multiple items and combine their effects

    If a passive item is consumed, you gain a small stat upgrade to a random stat

    Possible stat changes include: +1.0 flat damage, +0.5 tears, +0.2 speed, +0.2 shot speed, +0.5 range, +1.0 luck

    Void does not work on devil deal or shop items unless they have been bought first

    Using Void to absorb items in Boss Rush or Challenge Rooms counts as taking the items and will cause the encounter to start

    Using Void on one time use items such as Mama Mega or Diplopia will cause their effect to instantly trigger and will not give you further uses through activating Void again

    UNLOCK: Unlock this item by beating Delirium in The Void floor with Apollyon

      Type: Active

      Recharge time: 6 rooms

      Item Pool: Devil Room, Angel Room

    *, purple, swirl, spin, black

  • Pause

    ItemID: 478

    "Stop!"

    Quality: 1

    Upon use, this item freezes all enemies in the room until you press the fire button again or 30 seconds passes (whichever happens first)

    Unlike other active items, bosses are not immune to this effect

    Touching a frozen enemy will still hurt you

    This item doesn not affect troll bombs - they will still explode

      Type: Active

      Recharge time: 2 rooms

      Item Pool: Item Room

    *, green, robot, antenna

  • Smelter

    ItemID: 479

    "Trinket melter!"

    Quality: 3

    Upon use, the Smelter will destroy your currently held trinket and give you the effect permanently, allowing you to stack up lots of different trinket effects

    Holding the Smelter increases the chance for a trinket to drop. (2% chance for the end of room drop to become a trinket)

    If a trinket has been smelted, it won't appear a second time unless the entire trinket pool is exhausted or you restart the run (e.g. by doing a victory lap)

    UNLOCK: Unlock this item by beating Mom's Heart on Hard Mode with Apollyon

      Type: Active

      Recharge time: 6 rooms

      Item Pool: Shop

    *, grey, gray, brown, orange, steam, coffee, tea, drink, cup

  • Compost

    ItemID: 480

    "Gain more friends!"

    Quality: 2

    When used, Compost doubles up the current number of blue flies and spiders you have

    When picked up, Compost will also destroy every consumable on the ground in the current room and turn each of them into a blue fly or blue spider

    If you have no pickups on the ground in the current room and no other flies or spiders, Compost will spawn 1 blue fly or blue spider

      Type: Active

      Recharge time: 2 rooms

      Item Pool: Shop

    *, green, brown, grey, gray, ball, lump

  • Dataminer

    ItemID: 481

    "109"

    Quality: 0

    When used, this item will distort all the sprites and music, rotating graphics 90 degrees and translating them diagonally up/left, while leaving the hitbox in the same place. This can make it confusing while navigating the room

    Enemy hitboxes remain the same

    Dataminer will randomly increase or decrease one of your stats by a small amount when used

    Gives you the Fruit Cake effect for the room when used, which will give a random tear effect with every tear fired

    All visual and tear effects reset after leaving the room

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Item Room

    * data miner, red, pickaxe, minecraft, pixel

  • Clicker

    ItemID: 482

    "Change"

    Quality: 0

    When used, this item will randomly change you into another character and remove the last item you picked up

    All stat changes of the new character are applied (e.g. character damage multipliers)

    This item can only reduce your heart containers and will not increase them if you change back into a character with more health. This means if you roll into The Lost, changing back to another character will leave you with only 1/2 of a soul heart

    Cannot turn you into a character that isn't unlocked yet

    Also includes Lazarus II (Lazarus' revived form) and Dark Judas (effect of Judas' Shadow)

    It's also possible that this item will pick the same character, making it seem like nothing happened

      Type: Active

      Recharge time: 6 rooms

      Item Pool: Item Room

    *, grey, gray, black, remote, zapper, changer, building

  • MaMa Mega!

    ItemID: 483

    "BOOOOOOOOOM!"

    Quality: 3

    A one time use item that when used will explode all objects (i.e. rocks, poop) in the room and deal 200 damage to all enemies in the current room, as well as every other room for the remainder of the floor

    Also opens the boss rush door after Mom's Foot, blue womb door after Mom's Heart, secret rooms and super secret rooms

    Like all single-use items, this item cannot be absorbed and used multiple times by the Void item

    Entering a room with an angel statue will destroy it and automatically spawn one of the Angel mini bosses

    REPENTANCE - This now blows up machines, beggars and fireplaces too

      Type: Active

      Recharge time: One time use

      Item Pool: Shop, Bomb Beggar

    *, bomb, face, red, lips

  • Wait What?

    ItemID: 484

    "I can't believe it's not butter bean!"

    Quality: 0

    Upon use, this item will fart, pushing enemies away and causing a wave of rocks to spawn that spread outwards from Isaac in a circle, dealing 10 damage per hit to any enemies caught in it

    Can be used to open secret rooms

    Visually this item is very similar to Butter Bean

    The rock waves can destroy destructible objects, e.g. poop

      Type: Active

      Recharge time: 10 seconds

      Item Pool: Item Room

    *, white, yellow, bean

  • Crooked Penny

    ItemID: 485

    "50/50"

    Quality: 1

    When used, you have a 50% chance to double all items, consumables and chests in the current room

    If the effect fails, all pickups and items are deleted and Crooked Penny spawns 1 coin

    If there are no consumables currently on the floor, Crooked Penny spawns 1 coin

    This item works with items which can be purchased such as shop items, allowing you to spawn a free version if the effect triggers

    If used in a shop and the effect fails, a Restock box can be used to restore the shop items. This mechanic is very useful on Greed and Greedier modes

    UNLOCK: Unlock this item by defeating Delirium in The Void floor with Keeper

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Item Room, Shop, Beggar

    *, orange, brown, yellow, gold, coin, cent

  • Dull Razor

    ItemID: 486

    "I feel numb..."

    Quality: 1

    Upon use this item hurts Isaac without actually taking health away, allowing you to activate any items which trigger when taking damage without losing health

    UNLOCK: Unlock this item by defeating Delirium on The Void floor with Eve

      Type: Active

      Recharge time: 2 rooms

      Item Pool: Shop

    *, blue, pink, purple

  • Potato Peeler

    ItemID: 487

    "A pound of flesh..."

    Quality: 3

    When used, this item permanently removes one of your red heart containers and gives you a flat +0.2 Damage Up, the Anemic effect (+5 Range Up + red creep trail) and a Cube of Meat

    The Anemic effect will only last for the current room, but the Cube of Meat and Damage Up are both permanent

    Only works for red hearts and has no effect when used if you only have soul/black hearts

    Has no recharge time and can be used as often as you like

    It is possible to generate multiple meatboys by stacking more than 4 Cubes of Meat

      Type: Active

      Recharge time: None

      Item Pool: Shop, Demon Beggar

    *, brown, metal, silver, grey, gray

  • Metronome

    ItemID: 488

    "Waggles a finger"

    Quality: 0

    When used, this item gives you the effect of a random item for the rest of the room

    Using this item multiple times in the same room will replace the previous item's effect with a new one

    Certain items can be activated with this item which have unexpected effects and many items will do nothing

    Items do not grant consumable drops which would normally occur when that item is picked up

    Most flight-granting items have cosmetic effects only, and will not allow you to fly

    Items that usually give HP up will not give extra health when gained from Metronome

    UNLOCK: Unlock this item by defeating Greedier Mode with Eden

      Type: Active

      Recharge time: 2 rooms

      Item Pool: Item Room

    *, grey, gray, brown

  • D infinity

    ItemID: 489

    "Reroll forever"

    Quality: 1

    This dice allows you to press the Drop key to cycle between all possible dice effects and pick one to use

    Charge time scales based on the chosen dice, updating every time you use it

    Possible dice include: D4, D6, D8, D10, D12, D20, D100

    REPENTANCE - This item was completely reworked for Repentance and no longer forces a random dice use each time. You can pick which dice you want to use.

    UNLOCK: Unlock this item by defeating Delirium in The Void floor with Isaac

      Type: Active

      Recharge time: Varies

      Item Pool: Secret Room

    *, grey, gray, cube, box, oo, square

  • Eden's Soul

    ItemID: 490

    "..."

    Quality: 3

    A one time use active item that when used, will spawn 2 random item pedestals from the item pool associated with the current room (e.g. in an Angel room, this will spawn 2 Angel room items)

    Starts with 0 charge and requires 12 charges to use

    UNLOCK: Unlock this item by defeating Delirium in The Void floor with Eden

      Type: Active

      Recharge time: 12 rooms (one time use)

      Item Pool: Angel Room

    *, blue, circle, spikes

  • Acid Baby

    ItemID: 491

    "Pills pills pills!"

    Quality: 2

    Every 6-7 rooms Acid Baby will drop a random pill

    The first pill drops after 2 rooms

    Every time you use a pill, Acid Baby will deal 10 damage to all enemies and poison them for 6-7 ticks

    REPENTANCE - Poison effect is stronger, but Acid Baby's pill drop rate has been reduced to every 6-7 rooms (previously every 2-3 rooms)

      Type: Passive, Familiar

      Item Pool: Item Room

    *, brown, yellow, face, red, eyes, ghost

  • YO LISTEN!

    ItemID: 492

    "Yo listen!"

    Quality: 2

    +1 Luck Up

    A familiar fairy that will float around the room and highlight the location of any secret room doors, tinted rocks or trapdoors under rocks

    Upon entering a new room, if there is an undiscovered secret room or tinted rock, it will move directly to the point of interest, otherwise it will just randomly fly around the room

      Type: Passive, Familiar

      Item Pool: Item Room, Key Beggar

    * navi, blue, green, fly

  • Adrenaline

    ItemID: 493

    "Panic - power"

    Quality: 1

    For every empty red heart container, Isaac gains Damage Up and his body increases in size

    Only works on full hearts - damage does not change if Isaac is missing 1/2 of a heart in one container

    Healing empty red heart containers will remove the damage increases

    Has no effect for The Lost and ???, as they cannot gain red heart containers (except for counting towards the Spun transformation)

    Counts as 1 of 3 syringe items needed towards the Spun transformation

    REPENTANCE - Adrenaline now grants an increasingly higher damage bonus the more empty heart containers Isaac has

      Type: Passive

      Item Pool: Item Room, Demon Beggar

    * Adderline, pink, syringe, needle, injection

  • Jacob's Ladder

    ItemID: 494

    "Electric tears"

    Quality: 2

    Isaac gains electric tears, which fire 1-2 sparks of electricty in random directions upon hitting any object or enemy

    The electricty deals half of your normal tear damage

    Tear effects will still apply to your electricty sparks in a lot of cases (e.g. Spoon Bender will give them a homing effect)

    Tears which fall naturally to the floor at max range do not generate sparks

      Type: Passive

      Item Pool: Item Room

    *, silver, metal, grey, gray, blue, jacob ladder, jacobs ladder

  • Ghost Pepper

    ItemID: 495

    "Flame tears"

    Quality: 2

    Each tear now has a small chance to be a fire instead, which deals 23 damage to enemies that come in contact with it

    The fire will remain in place and shrink in size when deals damage to something. After dealing enough damage it will eventually disappear

    REPENTANCE - Ghost Pepper now shoots spectral blue flames that scale with Isaac's damage and luck.

      Type: Passive

      Item Pool: Item Room

    *, white, face

  • Euthanasia

    ItemID: 496

    "Needle shot"

    Quality: 3

    Each tear now has a small chance (3.33%) to be a needle instead, which deals 3 times your tear damage

    If a needle hits a non-boss enemy it will instantly kill it and will explode into a circle of 10 more needles

    The 10 spawned needles will also deal 3 times your tear damage, but won't instantly kill enemies or explode into more needles

    The chance to for each tear to become a needle is affected by your luck stat and at +15 Luck it will activate every time

    Counts as 1 of 3 syringe items needed towards the Spun transformation

    UNLOCK: Unlock this item by defeating Delirium in The Void floor with Lilith

      Type: Passive

      Item Pool: Item Room, Curse Room, Demon Beggar

    *, black, syringe, injection

  • Camo Undies

    ItemID: 497

    "Camo kid"

    Quality: 0

    Upon entering a new room, Isaac will become camouflaged and enemies won't attack until you start firing tears

    Bosses are immune to this effect

      Type: Passive

      Item Pool: Item Room

    *, pink, purple, goggles underwear under wear

  • Duality

    ItemID: 498

    "You feel very balanced"

    Quality: 1

    Any time a devil or angel room door opens after a boss, the other one will also spawn

    The extra door will only spawn if a devil or angel room was randomly chosen to spawn already

    After entering one of the doors, the other will disappear

    If there isn't an available wall for the extra door to spawn on, only one door will spawn (i.e. in a small boss room)

    UNLOCK: Unlock this item by defeating Greedier Mode with Lilith

      Type: Passive

      Item Pool: Devil Room, Angel Room

    *, black, white, circle

  • Eucharist

    ItemID: 499

    "Peace be with you"

    Quality: 3

    Gives you a 100% chance to find an Angel Room on every valid floor after defeating the boss

    Doesn't spawn an angel room on any floor where it is normally not possible to find one (e.g. Basement 1, Cathedral, Sheol etc.)

    Keeps the chance at 100% even after entering and leaving the angel room, meaning the door will not close after visiting

    Makes it impossible to find Devil Rooms again, unless you find a way to remove or reroll this item away, or find the Duality item

    UNLOCK: Unlock this item by defeating Delirium in The Void floor with Maggy

      Type: Passive

      Item Pool: Angel Room

    *, golden, yellow, white, cross

  • Sack of Sacks

    ItemID: 500

    "Gives Sacks!"

    Quality: 3

    A sack familiar that drops a sack every 5 or 6 rooms cleared (alternates between 5 and 6)

    UNLOCK: Unlock this item by defeating Greedier Mode as Cain

      Type: Passive, Familiar

      Item Pool: Secret Room

    * back in black, ac/dc, bag, brown, pouch, pocket, bulge

  • Greed's Gullet

    ItemID: 501

    "Money = Health!"

    Quality: 1

    Gives you an extra heart container for every 25 coins you are currently holding, up to a maximum of 4 extra HP at 99 coins held

    If your coin counter goes below the required amount for a heart container, you will lose it again

    This item works for the Keeper, allowing him to exceed his usual 2 health containers

    However, if Keeper drops to under 2 health coins as a result of Greed's Gullet, he is unable to use a HP Up to increase his health back to 2, and has to regain the lost coins to do so

    UNLOCK: Unlock this item by beating Challenge #35 (Pong)

      Type: Passive

      Item Pool: Secret Room

    *, dollar, cash, sack, bag, pouch, greeds gullet, greed gullet

  • Large Zit

    ItemID: 502

    "Creep shots"

    Quality: 1

    Gives you a random chance while firing tears to also fire a creep shot, which deals double your tear damage and places white creep on the floor infront of you that slows enemies down if they walk through it

    Unlike some similar tear effects, your luck stat does not alter the chance for this effect to activate

    A creep shot is also fired in a random direction after taking damage

      Type: Passive

      Item Pool: Item Room

    *, pink, yellow, toe, nail, tooth

  • Little Horn

    ItemID: 503

    "Science!"

    Quality: 3

    While firing tears you have a 5% chance to fire a void tear, that will instantly kill any non-boss enemy it comes into contact with

    The chance to for each tear to become a void tear is affected by your luck stat and at +15 Luck it will activate 20% of the time

    Isaac also grows a horn on his head, which causes you to deal contact damage to enemies by running into them (this effect deals base damage of 3.5 per tick)

    REPENTANCE - The visual effect was changed on this. Instead of just killing the enemy Big Horn now appears and grabs them, instantly killing them. Tears are no longer piercing

      Type: Passive

      Item Pool: Curse Room, Demon Beggar

    *, black, tooth

  • Brown Nugget

    ItemID: 504

    "Friendly Fly"

    Quality: 0

    When used, will spawn a fly turret that doesn't move and fires tears at nearby enemies

    Only persists for the current room

    The fly's bullets deal 3.5 damage each and do not scale with your own damage stat

    REPENTANCE - Brown Nugget flies now have faster shot speed, and their damage has been increased to 3.5 (from 2).

    UNLOCK: Unlock this item by defeating Ultra Greed as Apollyon

      Type: Active

      Recharge time: 7 seconds

      Item Pool: Item Room

    *, brown, cube, rock, brownie, dirt

  • Poke Go

    ItemID: 505

    "Gotta catch em..."

    Quality: 0

    At the start of each new hostile room, you have a 20% chance to gain a random charmed familiar which will fight for you

    The charmed enemy has its own health bar and will die if it takes enough damage

    Charmed enemies persist between each room and floor for as long as they stay alive

    Allows you to have more than one charmed familiar at a time if you can keep them alive

      Type: Passive

      Item Pool: Shop

    * pokemon, phone, black, green, blue, gps

  • BackStabber

    ItemID: 506

    "Watch your back!"

    Quality: 1

    Every time one of your tears hits an enemy, it has a chance to start bleeding, which will cause it to take damage equal to 10% of its maximum health every 5 seconds

    Damaging enemies from behind gives the bleed effect a 100% chance to apply

    The tear that inflicts the bleed effect also deals double damage

    The bleed effect cannot be applied to immune enemies (e.g. bosses and mini bosses)

      Type: Passive

      Item Pool: Item Room

    *, knife, dagger, red, heart, silver, knife

  • Sharp Straw

    ItemID: 507

    "More blood!"

    Quality: 2

    When used, Sharp Straw will deal damage to all enemies in the room

    The damage dealt is equal to Isaac's current tear damage plus 10% of the enemy's max health

    Every time this item deals damage, it has a 15% chance to drop 1/2 red hearts

    REPENTANCE - Sharp Straw is now only able to generate half red hearts (previously, it generated half soul hearts if the player had no heart containers)

      Type: Active

      Recharge time: 8 seconds

      Item Pool: Item Room

    *, blue, white, stripe

  • Mom's Razor

    ItemID: 508

    "It's sharp!"

    Quality: 1

    A razor blade orbital that deals contact damage and applies the bleeding status effect to enemies, which will cause them to take damage equal to 10% of their total health every 5 seconds

    The contact damage dealt by Mom's Razor is equal to 20% of your current tear damage (scales with damage upgrades)

    Does not block enemy shots

    The bleed effect does not affect bosses

    Its speed is not affected by the Guardian Angel item

    Counts as 1 of 3 mom items needed towards the Mom transformation

      Type: Passive, Familiar

      Item Pool: Item Room, Curse Room

    *, pink, moms razor, mom razor

  • Bloodshot Eye

    ItemID: 509

    "Bloody friend"

    Quality: 1

    An eye orbital that shoots tears that deal 3.5 damage and deals 2 contact damage per tick to enemies

    The damage dealt by this orbital does not scale with damage upgrades

    Its speed is not affected by the Guardian Angel item

    REPENTANCE - Bloodshot Eye now blocks enemy shots, has increased shot speed and rate of fire, and now only shoots when lined up with enemies

      Type: Passive, Familiar

      Item Pool: Item Room

    *, pink, red

  • Delirious

    ItemID: 510

    "Unleash the power!"

    Quality: 1

    When used, spawns a charmed random white delirium version of a boss, that will fight for you and kill other enemies for the rest of the current room

    Possible bosses spawned include most bosses in the game

    Some bosses' effects can harm Isaac. For example if the spawned boss leaves creep, it can damage Isaac

    UNLOCK: Unlock this item by defeating Delirium for the first time on any character

      Type: Active

      Recharge time: 12 rooms

      Item Pool: Angel Room

    *, yellow, eyes, face, round

  • Angry Fly

    ItemID: 511

    "He's violent"

    Quality: 1

    A familiar fly that orbits around a random enemy in the room until that enemy dies, dealing 2 contact damage to other enemies

    Angry Fly will move to the next enemy after the one it is currently orbiting dies, until the room is cleared, at which point it will return to orbiting Isaac

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Custom Phase

    UNLOCK: Unlock this item by transforming into Beelzebub (Achieved by picking up 3 fly related items, see Transformations page for full list)

      Type: Passive, Familiar

      Item Pool: Item Room

    *, red, cube, wings, face

  • Black Hole

    ItemID: 512

    "Nothing can escape"

    Quality: 1

    A throwable active item that places a black hole on the ground where it lands, sucking all enemies into it for 6 seconds

    Enemies stuck inside the black hole take rapid damage over time

    The Black Hole will also suck Isaac into it, but with a much weaker effect than to enemies

    The Black Hole will destroy nearby obstacles such as rocks and pots

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Custom Phase

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Item Room

    *, pink, purple, black, planet

  • Bozo

    ItemID: 513

    "Party time!"

    Quality: 2

    +0.1 Damage Up

    +1 Soul Heart

    Adds a random chance for an enemy in the current room to become charmed or feared briefly

    Adds a random chance to spawn a rainbow poop upon taking damage

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Electoon

    UNLOCK: Unlock this item by breaking 5 rainbow poops

      Type: Passive

      Item Pool: Item Room

    *, red, white, stripe, hat, clown, waldo, wally

  • Broken Modem

    ItemID: 514

    "LAG!"

    Quality: 1

    Causes random enemies to 'lag' at random intervals, causing them to freeze in place for a second

    The lag effect can also apply to tears, projectiles and consumables on the ground

    While held, this trinket has a 25% chance to double up any end of room drops (similar to the Contract from Below effect)

    Isaac's Luck stat affects how often the lag effect occurs

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Freezenification

    UNLOCK: Complete 7 Daily Challenges (30 on console)

      Type: Passive

      Item Pool: Shop

    *, black, cube, red, vcr, vhs

  • Mystery Gift

    ItemID: 515

    "Wrapped up nice for you!"

    Quality: 3

    A one-time use item that spawns a random item from the current room's item pool, with a chance for it to spawn Lump of Coal or The Poop instead

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Mills

      Type: Active

      Recharge time: One time use

      Item Pool: Shop

    *, green, red, present, bow, xmas, christmas

  • Sprinkler

    ItemID: 516

    "Sprinkles."

    Quality: 2

    When used, spawns a Sprinkler that rotates in a circle, spraying tears in all directions

    Will also synergize with some other items, such as Mom's Eye, Brimstone, Dr. Fetus, Tech X or Loki's Horns

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Kieran and Stewartisme

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Item Room

    *, grey, gray, silver, metal, eye, stick

  • Fast Bombs

    ItemID: 517

    "Faster Bomb Drops!"

    Quality: 1

    +7 Bombs

    Allows you to rapidly place bombs on the ground

    Added as part of the Afterbirth+ Booster Pack #1

    REPENTANCE - Bombs no longer knock each other around when the player has Fast Bombs, allowing for a more controlled line of explosions.

    UNLOCK: Unlock this item by defeating Lil Horn 20 times

      Type: Passive

      Item Pool: Item Room

    *, lightning, bolt, yellow, black

  • Buddy in a Box

    ItemID: 518

    "What could it be?!"

    Quality: 2

    When picked up, gives Isaac a random familiar which has a random sprite and tear effect

    The familiar will be fully randomized again upon entering the next floor

    The appearance is chosen from a random co-op baby sprite

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Ashkait and Scayze

      Type: Passive, Familiar

      Item Pool: Shop

    *, brown, orange, snake, mgs, cardboard

  • Lil Delirium

    ItemID: 519

    "He's Delirious"

    Quality: 2

    A familiar that will transform into another random familiar every 10 seconds, copying their behaviour and effect

    Can be any other familiar, including (but not limited to) Lil Brimstone, Bob's Brain, BBF, Meatboy, Rotten Baby

    Familiars appear as a white Delirium version of the original

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Ashkait and Scayze

      Type: Passive, Familiar

      Item Pool: Angel Room, Devil Room

    *, white, yellow, eyes, face, circle

  • Jumper Cables

    ItemID: 520

    "Bloody recharge!"

    Quality: 3

    This item gives you 1 bar of charge on your active item for every 15 enemies you kill

    Added as part of the Afterbirth+ Booster Pack #2 and based on the Steam Workshop mod created by Ashkait and Scayze

    UNLOCK: Unlock this item by picking up any 3 of these items in a single run: 9 Volt, The Battery, Car Battery, AAA Battery, Watch Battery

      Type: Passive

      Item Pool: Greed Mode Item Room, Shop

    *, red, black, metal, crocodile, clips

  • Coupon

    ItemID: 521

    "Allow 6 weeks for delivery"

    Quality: 2

    When used, the coupon causes one random item in the shop to become free

    While held, guarantees a random item or pickup from the shop to be half price

    The effect of this item also works in Devil Rooms, allowing you to take one random item for free

    Added as part of the Afterbirth+ Booster Pack #2 and based on the Steam Workshop mod created by Plumbo

      Type: Active

      Recharge time: 6 rooms

      Item Pool: Item room, Shop, Beggar

    *, paper, square, green, pink, white, barcode, letter, postcard

  • Telekinesis

    ItemID: 522

    "The power of mind!"

    Quality: 1

    An active that causes all enemy tears to be held in place and then thrown back away from Isaac for a period of 3 seconds

    The aura from this item will repel nearby enemies

    Added as part of the Afterbirth+ Booster Pack #2

      Type: Active

      Recharge time: 6 seconds

      Item Pool: Item Room, Greed Mode Item Room

    *, blue, glow, hand

  • Moving Box

    ItemID: 523

    "Pack and unpack"

    Quality: 1

    When used, the box will pick up a maximum of 6 items. Using the box again will put the picked up items back on the floor again, allowing you to move things between rooms

    Can move any of the following: Batteries, Items, Trinkets, Hearts, Keys, Bombs, Coins, Chests and more

    Using Moving Box with Car Battery will trigger 2 interactions at the same time: First it will drop all items currently inside the box and secondly will then pick up the current room's contents

    When used in a room with 2 items you can choose from (e.g. There's Options, Double item room, Boss Rush) the Moving Box will pick only one of the items at random

    Added as part of the Afterbirth+ Booster Pack #2 and based on the Steam Workshop mod created by HurleyFarrill

    UNLOCK: Unlock this item by using Pandora's Box in the Dark Room floor

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Shop

    *, brown, orange, cardboard

  • Technology Zero

    ItemID: 524

    "Static tears!"

    Quality: 3

    Your tears will now be connected together by beams of electricity which deals damage to enemies they hit

    The lasers from this item deal 30% of your current damage stat

    Added as part of the Afterbirth+ Booster Pack #2 and based on the Steam Workshop mod created by Ashkait and Scayze

    REPENTANCE - Technology Zero's lasers now deal 30% of the player's damage stat per tick (from 100%)

    UNLOCK: Unlock this item by having 2 technology items at once

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, black, white, grey, gray, round, circle, eye, key, hole, coin, slot, laser

  • Leprosy

    ItemID: 525

    "You're tearing me apart!"

    Quality: 1

    Taking damage will spawn an orbital that rotates around Isaac, dealing contact damage to enemies and blocking enemy projectiles

    A maximum of 3 Leprocy orbitals can be active at one time

    Using the orbital to deal damage to enemies can cause it to break

    Added as part of the Afterbirth+ Booster Pack #2. Based loosely on the Steam Workshop mod created by Extreme Ninja Home Makeover with changes by Edmund McMillen

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *, lepracy, leprasy, leprosy, pink, red, bloody, lump

  • 7 Seals

    ItemID: 526

    "Lil Harbingers!"

    Quality: 2

    Gives you a random Harbinger familiar that changes every 10 seconds

    Each harbinger behaves differently, based on any of the original 5 horsemen bosses

    REPENTANCE - The harbingers will also randomly spawn their relevant Locust variant. The locust fly will do different things for each harbinger - e.g. poison effect for Pestilence

    Added as part of the Afterbirth+ Booster Pack #3. Based on the Steam Workshop mod created by by Scayze and Ashkait

      Type: Passive

      Item Pool: Devil Room, Angel Room

    *, bloody, paper, script, white, red, toilet paper, seven seals

  • Mr. ME!

    ItemID: 527

    "Caaan Do!"

    Quality: 3

    Upon use, this item summons a ghost near Isaac that will follow him around. Also summons a blue crosshair which can be moved around freely. After a few seconds, the crosshair will disappear, and the Ghost will do certain things based on what you targeted:

    Items, pickups, trinkets: Brings them to Isaac. Works in shops and devil deals as well, allowing you to take them for no cost. Stealing an item has a chance to fail (a buzzer sound will play if it fails)

    Buttons: Presses the button

    Enemies: Attacks the enemy until either the ghost or the enemy dies

    Doors: Opens the door, even if it is locked

    Secret room entrances: Explodes and opens the entrance

    Boss rush door: Will open the Boss Rush door from either side, allowing you get into and escape the Boss Rush

    Slot machines, dead shopkeepers: Charges towards them and explodes them

    Added as part of the Afterbirth+ Booster Pack #3. Based on the Steam Workshop mod created by Jean-Alphonse

    UNLOCK: Unlock this item by opening 20 locked chests

      Type: Active

      Recharge time: 4 rooms

      Item Pool: Shop, Key Beggar

    *, mr me!, Mr Meeseeks, rick and morty, brown, chest, szechuan sauce, mister me

  • Angelic Prism

    ItemID: 528

    "Eclipsed by the moon"

    Quality: 3

    Grants a prism orbital with a large orbital radius

    Isaac's tears that pass through the prism split into four multi-colored tears

    Does not deal contact damage to enemies that it passes over

    Added as part of the Afterbirth+ Booster Pack #3. Based on the Steam Workshop mod created by electoon and Erfly

      Type: Passive, Orbital

      Item Pool: Angel Room

    *, dark side of the moon, rainbow, red, yellow, green, white, triangle, pink floyd, thought

  • Pop!

    ItemID: 529

    "Eyeball tears!"

    Quality: 2

    Replaces Isaac's tears with eyeballs that can bounce off of each other

    Issac's tears are no longer limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle

    Added as part of the Afterbirth+ Booster Pack #3. Based on the Steam Workshop mod created by Scayze and Ashkait

      Type: Passive

      Item Pool: Item Room

    *, eyes, eyeball, bloody, white, red, googly googley, bank shot

  • Death's List

    ItemID: 530

    "Just hope you're not next"

    Quality: 2

    Upon entering a room, a skull appears over a random enemy's head

    Killing the marked enemy will cause the skull to move to a different enemy

    If all enemies in the room are cleared in the order they are marked, Isaac gains a random reward from one of the following: Soul heart, Key, Pill, Bomb, Nickel, +0.2 Speed, +0.5 Range, +0.5 Tears, +1 Flat damage or +1 luck

    Killing enemies in the wrong order will end the streak and deny you any extra rewards

    Added as part of the Afterbirth+ Booster Pack #4. Based on the Steam Workshop mod created by Merlo

      Type: Passive

      Item Pool: Devil Room

    *, parchment, quill, script, pact, feather, scroll, death list, deaths list

  • Haemolacria

    ItemID: 531

    "I'm seeing red..."

    Quality: 2

    With Haemolacria, Isaac's tears become bloody and now fire by in the air in an arc

    Upon hitting the floor, an obstacle or enemy, the bloody tear will burst and fire lots of smaller tears at random directions around the impact point

    Tears Down - (Tear delay * 2) + 10

    Your damage stat is unaffected by this item, however the large bloody tear does +31% of your tear damage and the smaller scattering tears deal 50-80% of your tear damage

    Added as part of the Afterbirth+ Booster Pack #4. Based on the Steam Workshop mod (originally called Water Balloon) created by HiHowAreYou

    UNLOCK: Unlock this item by picking up the Blood Clot item 10 times

      Type: Passive

      Item Pool: Item Room

    *, water balloon, blood, heamolacria

  • Lachryphagy

    ItemID: 532

    "Feed them!"

    Quality: 2

    Isaac's tears slow down over time while moving across the room, and upon stopping completely or hitting an object will burst into 8 smaller tears which fire in all directions

    This item will also allow you to 'feed' a tear with other tears. Doing so will cause it to increase in size, and also increase their damage and the damage of the burst tears

    Once a tear is fed 5 times, it will immediately burst

    Tears in the burst will deal half the damage the main tear would have

    Tears which hit an enemy do not burst

    Added as part of the Afterbirth+ Booster Pack #4. Based on the Steam Workshop mod (originally called Hungry Tears) created by Echo

      Type: Passive

      Item Pool: Item Room

    *,

  • Trisagion

    ItemID: 533

    "Smite thy enemy"

    Quality: 2

    Isaac's tears are replaced with piercing holy flashes of light, which travel across the room in a similar speed to regular tears

    Trisagion tears deal roughly 33% of your usual tear damage, however due to the size of the holy flash it is likely to hit enemies multiple times

    Trisagion tears cause no knockback on enemies and simply travel through them (piercing tears)

    Added as part of the Afterbirth+ Booster Pack #4. Based on the Steam Workshop mod (originally called Lightshot) created by Wyvern and TRPG

      Type: Passive

      Item Pool: Angel Room

    *,

  • Schoolbag

    ItemID: 534

    "Extra active item room"

    Quality: 3

    Gives you an extra active item slot

    Pressing the CTRL key allows you to switch active items

    Functions exactly the same as the Antibirth item with the same name

    Added as part of the Afterbirth+ Booster Pack #4

    UNLOCK: Unlock this item by entering every Shop from the first floor up to Mom's Heart (Depths 2)

      Type: Passive

      Item Pool: Shop, Gold/Stone Chest

    *, backpack back pack school bag

  • Blanket

    ItemID: 535

    "You feel safe"

    Quality: 1

    +1 Soul Heart

    Heals 1 red heart when picked up

    Grants you a shield when entering the Boss Room, which prevents damage from 1 hit, then disappears

    Added as part of the Afterbirth+ Booster Pack #5. Based on the Steam Workshop mod created by Ratlah

    UNLOCK: Unlock this item by sleeping in 10 different beds

      Type: Passive

      Item Pool: Shop

    *,

  • Sacrificial Altar

    ItemID: 536

    "He demands a sacrifice"

    Quality: 2

    When used, this item will sacrifice up to 2 of your familiars (chosen at random), and spawn a random Devil Room item for each familar sacrificed this way

    In addition to the familiars, any blue flies or spiders will be converted to 1 coin each

    If Guardian Angel, Sworn Protector, or Seraphim is sacrificed, Satan will be extra happy and reward you with 2 black hearts

    Incubus won't be sacrificed if you're playing as Lilith

    If used while you have no familiar, this item will do nothing and won't consume the item

    Added as part of the Afterbirth+ Booster Pack #5. Based on the Steam Workshop mod created by Niro

      Type: Active

      Recharge time: Single use

      Item Pool: Curse Room

    *, sacraficial, sacrafice

  • Lil Spewer

    ItemID: 537

    "Puking buddy"

    Quality: 1

    A familiar with a charged attack, that spawns a line of creep on the floor which damages enemies that walk over it

    Spawns 1 random pill when picked up

    The familiar and its creep will change randomly when Isaac uses a pill

    Possible creep types include green (deals damage), black (slows enemies), red (deals damage, forms a line with a larger puddle), yellow (deals damage, forms a short-range cone) and white (slows enemies, forms a ring)

    Added as part of the Afterbirth+ Booster Pack #5. Based on the Steam Workshop mod created by Strawrat and Aczom

    UNLOCK: Unlock this item by dying to your own Ipecac explosion

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *,

  • Marbles

    ItemID: 538

    "Choking hazard"

    Quality: 2

    Spawns 3 random trinkets when picked up

    Upon taking damage, you have a random chance to consume one of your currently held trinkets, gaining its effect permanently

    Added as part of the Afterbirth+ Booster Pack #5. Based on the Steam Workshop mod created by Amethyst

    UNLOCK: Unlock this item by using 5 Gulp! pills in one run

      Type: Passive

      Item Pool: Boss Room

    *,

  • Mystery Egg

    ItemID: 539

    "Sacrificial insemination"

    Quality: 1

    A familiar which follows Isaac and, upon taking damage, will spawn a charmed enemy that will fight for you

    When the charmed enemy is spawned the egg will crack, but regenerate in the next room

    Added as part of the Afterbirth+ Booster Pack #5. Based on the Steam Workshop mod created by Strawrat and Aczom

    UNLOCK: Unlock this item by spawning 3 charmed enemies in a single room

      Type: Passive

      Item Pool: Item Room

    *,

  • Flat Stone

    ItemID: 540

    "Skipping tears"

    Quality: 2

    Flat Stone causes your tears to bounce across the room

    Whenever a tear bounces, it deals splash damage to nearby enemies for 25% of your tear damage

    Added as part of the Afterbirth+ Booster Pack #5. Based on the Steam Workshop mod created by Maddogs

    UNLOCK: Unlock this item by picking up Rubber Cement 5 times

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *,

  • Marrow

    ItemID: 541

    "HP up?"

    Quality: 1

    +1 Bone Heart

    Spawns 3 red hearts on the ground when picked up

    Added as part of the Afterbirth+ Booster Pack #5

    UNLOCK: Unlock this item by defeating Mom's Heart on hard mode as The Forgotten

      Type: Passive

      Item Pool: Boss Room

    *,

  • Slipped Rib

    ItemID: 542

    "Projectile shield"

    Quality: 2

    This item gives you an orbital, which will reflect projectiles back at enemies

    Unlike some other orbitals, Slipped Rib doesn't deal contact damage to enemies

    Added as part of the Afterbirth+ Booster Pack #5

    UNLOCK: Unlock this item by defeating the Isaac boss as The Forgotten

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *,

  • Hallowed Ground

    ItemID: 543

    "Portable sanctuary"

    Quality: 1

    A familiar which follows Isaac and spawns a white poop when you take damage

    The white poop gives an aura that cuts your tear delay in half (Tears up) and has a chance to block damage

    The aura disappears if the poop is destroyed

    Added as part of the Afterbirth+ Booster Pack #5

    REPENTANCE - White poop from Hallowed Ground is now more durable, similar to golden poop. While standing in the aura, Isaac's damage is now also increased by 25%, and his tears gain a homing effect

    UNLOCK: Unlock this item by defeating Hush as The Forgotten

      Type: Passive

      Item Pool: Item Room, Angel Room

    *,

  • Pointy Rib

    ItemID: 544

    "Stabbing time"

    Quality: 2

    A familiar that can be aimed with the fire buttons similar to the Finger item, dealing contact damage to enemies equal to your tear damage

    Added as part of the Afterbirth+ Booster Pack #5

    UNLOCK: Unlock this item by defeating Satan as The Forgotten

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *,

  • Book of the Dead

    ItemID: 545

    "Rise from the grave"

    Quality: 2

    When used, this item will spawn a bone orbital or charmed Bony for each enemy killed in the current room

    The orbitals and charmed enemies persist when travelling between rooms

    Bone orbitals break after dealing enough damage or blocking too many shots

    Added as part of the Afterbirth+ Booster Pack #5

    Counts as 1 of 3 book items needed towards the Bookworm transformation.

    UNLOCK: Unlock this item by defeating Delirium in The Void floor as The Forgotten

      Type: Active

      Recharge time: 6 rooms

      Item Pool: Item Room, Library, Devil Room

    *,

  • Dad's Ring

    ItemID: 546

    "Father's blessing"

    Quality: 3

    A passive item that puts a yellow ring around Isaac. Enemies are frozen in place while touching the yellow ring

    Enemies touching the ring will stay permanently frozen until you move away, except for bosses which only get a temporary freeze effect after touching it

    Added as part of the Afterbirth+ Booster Pack #5

    UNLOCK: Unlock this item by defeating Ultra Greedier as The Forgotten

      Type: Passive

      Item Pool: Secret Room

    *, dads ring, dad ring

  • Divorce Papers

    ItemID: 547

    "Tears up + you feel empty"

    Quality: 2

    +1 Bone Heart

    +0.7 Tears Up

    When you pick this item up, the Mysterious Paper trinket is spawned on the ground

    Added as part of the Afterbirth+ Booster Pack #5

    UNLOCK: Unlock this item by defeating Boss Rush as The Forgotten

      Type: Passive

      Item Pool: Boss Room

    *,

  • Jaw Bone

    ItemID: 548

    "Fetch"

    Quality: 1

    A familiar that flies across the room every few seconds while firing and damages enemies (2x your tear damage)

    Can also be used like the Boomerang to pick up consumables on the ground

    Added as part of the Afterbirth+ Booster Pack #5

    UNLOCK: Unlock this item by defeating ??? in The Chest floor as The Forgotten

      Type: Passive

      Item Pool: Item Room, Greed Mode item Room

    *,

  • Brittle Bones

    ItemID: 549

    "Everything hurts"

    Quality: 3

    When picked up, this item replaces all of your red heart containers with 6 Bone Hearts

    Every time you lose a bone heart, lots of bones fire in all directions damaging any enemies hit and you gain a permanent +0.5 Tears Up

    For the Lost and Keeper characters, this item simply gives a permanent Tears Up

    Added as part of the Afterbirth+ Booster Pack #5

    UNLOCK: Unlock this item by defeating The Lamb in the Dark Room floor as The Forgotten

      Type: Passive

      Item Pool: Item Room, Greed Mode Item Room

    *,

  • Broken Shovel

    ItemID: 550

    "It feels cursed"

    Quality: 4

    Obtained by beating the Basement 1 boss within 1 minute, then bombing the large shadow that appears in the middle of the starting room

    While held, Mom's Foot will stomp on you from above twice every few seconds, and she will continue to stomp for as long as you hold this item

    Using the Broken Shovel will stop Mom stomping you for the rest of the current room (or current wave if you're in the boss rush or challenge room)

    Beating the Boss Rush while holding this item will drop the second half of the Broken Shovel, which combine to create Mom's Shovel, which is used to unlock The Forgotten character

    Dropping the Broken Shovel will cause it to disappear if you leave the room

    NOTE: This item will not drop unless you have beaten The Lamb at least once

    Added as part of the Afterbirth+ Booster Pack #5 and used in the quest to unlock The Forgotten character

      Type: Active

      Recharge time: 4 rooms

    *,

  • Broken Shovel

    ItemID: 551

    "Lost but not forgotten"

    Quality: 4

    Drops after beating the Boss Rush while holding the other half of the Broken Shovel (see previous item for more details)

    Combines with the first Broken Shovel piece to create Mom's Shovel (see next item for more details)

    Added as part of the Afterbirth+ Booster Pack #5 and used in the quest to unlock The Forgotten character

      Type: Passive

    *,

  • Mom's Shovel

    ItemID: 552

    "Lost but not forgotten"

    Quality: 4

    When used, spawns a trapdoor that leads to the next floor (has a 10% chance to be a crawl space instead)

    Unlocks The Forgotten character when used on a mound of dirt that appears in a room in The Dark Room floor

    Obtained by combining the two Broken Shovel pieces. The first piece drops by beating the first floor boss within 1 minute then bombing the shadow in the first room. The second piece drops after beating the Boss Rush as long as you are holding the first Broken Shovel piece (see previous 2 items for full details)

    After The Forgotten is unlocked, using it on the mound of dirt again just spawns a random type of chest

    Added as part of the Afterbirth+ Booster Pack #5 and used in the quest to unlock The Forgotten character

      Type: Active

      Recharge time: 4 rooms

    *, moms shovel, mom shovel

  • Rebirth Trinkets

  • Swallowed Penny

    TrinketID: 1

    "Gulp!"

    Each time you get hit, you drop a coin or two

    REPENTANCE - No longer guaranteed to drop coins as The Keeper

    UNLOCK: Unlock this item by beating Challenge #15 (Slow Roll)

    * , the lost item pool, cent, gold, water, wet, blue

  • Petrified Poop

    TrinketID: 2

    "It feels lucky?"

    While held, Isaac has a significantly higher chance to find drops when breaking poops

    *, grey, gray

  • AAA Battery

    TrinketID: 3

    "Trickle charge"

    Lowers your spacebar item charge rate by 1

    Cannot lower the charge of your spacebar item below 1 room

    For example, you will now be able to use a 3 room charge item after 2 rooms instead

    *, bullet, grey, gray, yellow

  • Broken Remote

    TrinketID: 4

    "It's broken"

    Does the teleport effect every time you use your current spacebar item

    Can be used infinitely every room if you have Guppy's Paw and no red heart containers (Can be exploited to get to the boss room without clearing any other rooms)

    *, joystick, grey, gray

  • Purple Heart

    TrinketID: 5

    "Challenge up"

    Higher chance for champion enemies while held

    *

  • Broken Magnet

    TrinketID: 6

    "It kinda works"

    Has a partial Magneto effect and will attract coins, pulling them into Isaac from a distance

    Does not attract other pickups like the full Magneto item does

    *, red

  • Rosary Bead

    TrinketID: 7

    "Faith up"

    Increases your chances to find an Angel Room instead of a Devil Room

    Normally there is a 50%/50% chance of a Angel or Devil room with if a door spawns after the boss. The Rosary Bead changes this to a 75%/25% chance of an angel or devil room (respectively)

    *, red, black, circle

  • Cartridge

    TrinketID: 8

    "I remember these"

    When Isaac takes damage, there is a chance he will gain the Gamekid effect, turning him invincible and dealing contact damage to any enemies he touches

    The chance to activate the invincibility effect is affected by your luck stat and at +38 Luck it will activate every time you get hit

    * , the lost item pool, nes, game, grey, gray

  • Pulse Worm

    TrinketID: 9

    "Wub wub!"

    Tears shrink and grow in size as they go across the room

    Does not appear to affect your damage and only the hitbox size of tears

    *, white, lump

  • Wiggle Worm

    TrinketID: 10

    "Wiggle wiggle!"

    Tears now move in a wave fashion across the room

    Grants spectral tears

    +0.4 Tears up

    *, white, s, snake

  • Ring Worm

    TrinketID: 11

    "Woop woop!"

    While held, tears move in a spiral pattern across the screen at high speed

    Grants spectral tears

    Effectively increases your range due to the tear pattern

    *, white, circle, snake

  • Flat Worm

    TrinketID: 12

    "Blub blub!"

    Tears become flat and disc shaped giving them a larger hitbox

    Higher knockback effect with your tears

    *, grey, gray, eyes

  • Store Credit

    TrinketID: 13

    "YES!"

    While this trinket is held, all items in the Shop cost 0 coins

    After buying any 0 cent item in the Shop, the trinket disappears

    UNLOCK: Unlock this item by beating the Chest with Lazarus

    *, grey, gray, dollar, bill, note, cash, money

  • Callus

    TrinketID: 14

    "Your feet feel stronger"

    Isaac no longer takes damage from walking over spikes and blood creep while this trinket is held

    * , the lost item pool, brown, pink, lump, ball, spot

  • Lucky Rock

    TrinketID: 15

    "There's something inside"

    33% chance to drop a coin for every rock that you destroy

    REPENTANCE - Previously was 100%, now 33%

    UNLOCK: Unlock this item by destroying 100 rocks

    *, grey, gray, stone, square

  • Mom's Toenail

    TrinketID: 16

    "???"

    Mom's Leg will now appear every 60 seconds and stomp down randomly in the room dealing 300 damage to enemies, similar to how Daddy Longlegs works but less frequent

    Be warned though, Mom's leg can also stomp and hurt Isaac too!

    *, mustache, moustache, white, yellow, moms toenail

  • Black Lipstick

    TrinketID: 17

    "Evil up"

    Increases the chance for Black hearts to spawn

    UNLOCK: Unlock this item by beating the Dark Room with Eve

    * , the lost item pool, grey, gray, makeup

  • Bible Tract

    TrinketID: 18

    "Faith up"

    Gives you a higher chance of eternal hearts

    Contrary to popular belief, the Bible Tract doesn't allow Angel Rooms to appear after paying for a Devil Deal

    * , the lost item pool, grey, gray, black, book

  • Paper Clip

    TrinketID: 19

    "Master of lockpicking"

    Allows you to unlock golden chests without needing a key

    Does not work on locked rooms

    Cain starts with this trinket after donating 68 coins to the Greed Donation Machine

    * starting, grey, gray, metal, wire

  • Monkey's Paw

    TrinketID: 20

    "Wish granted"

    When you reach half a heart of life remaining, a black heart will spawn

    After three black hearts have spawned, the trinket dissapears

    * , the lost item pool, hand, brown, monkeys paw

  • Mysterious Paper

    TrinketID: 21

    "???"

    Imitates the behaviours of some of the other 'paper' items/trinkets

    A Missing Page: When taking damage, Isaac has a chance to deal damage to the entire room in a Necronomicon style effect

    Has a chance to trigger the Polaroid or Negative effect every time you take damage with half a red heart or less

    Missing Poster: Dying in a sacrifice room while holding this trinket will reveal a puzzle piece on the death screen. Finding all the puzzle pieces will help you to reveal the final secret, unlocking the hidden character 'The Lost'

    If held when you touch the chest after the Satan or Isaac fight and you don't have the relevant item to go to the next floor (Polaroid or Negative), you have a small chance to be taken there anyway

    UNLOCK: Unlock this item by beating the Chest with Eden

    *, white, grey, gray, page

  • Daemon's Tail

    TrinketID: 22

    "Evil up"

    Every time a heart would spawn, it becomes a key instead.

    Hearts turn into black hearts. This doesn't convert hearts that dropped before picking up this trinket, and doesn't apply to set hearts, i.e. the eternal hearts that drop in angel rooms

    UNLOCK: Unlock this item by beating Satan with Azazel

    *, black, devil, pointy, daemons tail, demons tail, demon tail

  • Missing Poster

    TrinketID: 23

    "???"

    Dying in a sacrifice room while holding this trinket will unlock The Lost character

    After The Lost is unlocked, dying anywhere with this trinket will bring you back to life as The Lost and the trinket will be deleted

    When playing as Tainted Lost, you don't swap to being regular Lost, it simply acts as an extra life

    UNLOCK: Unlock this item by beating Dark Room with Isaac

    *, page, paper, isaac, white, writing

  • Butt Penny

    TrinketID: 24

    "Wealth of gas"

    Everytime you pick up a coin, you fart

    *, brown, orange, flat

  • Mysterious Candy

    TrinketID: 25

    "Uh-oh!"

    Causes Isaac to create poops randomly

    *, chocolate, brown, rectangle

  • Hook Worm

    TrinketID: 26

    "Zip zoop!"

    Tears now move forwards at right angles, shifting left and right across the room

    Grants spectral tears

    Increases your range stat by +10.0 while held but due to the fire pattern, your tears travel a similar distance to normal

    *, white, snake, square

  • Whip Worm

    TrinketID: 27

    "Wooosh!"

    +0.5 Shot Speed Up

    Your tears now whip across the room at a very high shot speed

    Shot speed gives your tears more effective range, but doesn't increase your range stat directly

    *, snake, white

  • Broken Ankh

    TrinketID: 28

    "Eternal life?"

    Has a 22.22% chance to respawn with 3 Soul hearts as Blue Baby when you die

    UNLOCK: Unlock this item by beating Satan with Lazarus

    *, ank, grey, gray

  • Fish Head

    TrinketID: 29

    "It stinks"

    Everytime Isaac takes damage, one blue fly will spawn

    * , the lost item pool, green, red, bloody, dead

  • Pinky Eye

    TrinketID: 30

    "Poison shots"

    Isaac's tears have a chance to poison enemies

    The poison effect leaves a damage over time, which deals 4 or 6 damage per tick

    The chance to poison enemies is affected by your luck stat and at +18 Luck it will activate every time

    *, red

  • Push Pin

    TrinketID: 31

    "Piercing shots"

    Isaac now has a chance to make a spectral and piercing tear

    The chance to fire a piercing tear is affected by your luck stat and at +18 Luck it will activate every time

    *, blue

  • Liberty Cap

    TrinketID: 32

    "Touch fuzzy, get dizzy!"

    While held, this trinket gives a random mushroom effect each room

    Possible mushrooms include: Mini Mush, Odd Mushroom (Thin), Odd Mushroom (Thick), The Compass

    *, ping, pong, paddle, grey, gray, mushroom

  • Umbilical Cord

    TrinketID: 33

    "Fetal protection"

    While at 1/2 a red heart of health, you gain a Little Steve familiar that follows you and shoots homing tears

    REPENTANCE - Umbilical Cord now has a high chance to spawn a Gemini familiar for the room when Isaac takes damage. This effect is stackable

    *, the lost item pool, pink, red, guts, intestine, tube

  • Child's Heart

    TrinketID: 34

    "It calls out to its brothers"

    Gives Isaac a higher chance to find hearts from drops after clearing a room and from chests

    * , the lost item pool, red, purple, childs heart, child heart

  • Curved Horn

    TrinketID: 35

    "DMG up"

    +2 Damage Up

    UNLOCK: Unlock this item by beating the Dark Room with Judas

    *, pink, purple, twisted

  • Rusted Key

    TrinketID: 36

    "It feels lucky?"

    Gives Isaac a higher chance to find keys and chests

    *, brown, wooden, broken

  • Goat Hoof

    TrinketID: 37

    "Speed up"

    +0.15 Speed Up

    * grey, gray, bloody, square

  • Mom's Pearl

    TrinketID: 38

    "It emanates purity"

    Grants a secondary chance of any non-specific heart drop turning into a soul heart

    * , the lost item pool, white, grey, gray, circle, round, moms pearl

  • Cancer

    TrinketID: 39

    "Yay, cancer!"

    -2 Tear Delay (Tears Up)

    The fire rate increase is applied in such a way that the higher your tear stat is, the more effective Cancer is

    Breaks the normal fire rate cap, allowing you to fire faster than the normal maximum

    *, green, brown, red, saddle, tube

  • Red Patch

    TrinketID: 40

    "Your rage grows"

    You have a chance when taking damage to gain +1.8 Damage Up for the rest of the room

    *, the lost item pool

  • Match Stick

    TrinketID: 41

    "Tastes like burning"

    Gives Isaac a higher chance to find bombs

    Picking up the Match Stick is the only way to remove the Tick trinket

    *, red, white

  • Lucky Toe

    TrinketID: 42

    "Luck up!"

    +1 Luck Up while held

    UNLOCK: Unlock this item by blowing up 20 shop keepers (this includes the ones in the secret room)

    *, finger, thumb, nail, bone

  • Cursed Skull

    TrinketID: 43

    "Cursed?"

    When you take damage while on 1/2 a heart, you are teleported back to the previous room

    * , the lost item pool, head, bone, grey, gray,

  • Safety Cap

    TrinketID: 44

    "Don't swallow it"

    Gives Isaac a higher chance to find pills

    *, white, pill

  • Ace of Spades

    TrinketID: 45

    "Luck of the draw"

    Gives Isaac a higher chance to find Tarot cards after clearing a room or from chests

    *, card

  • Isaac's Fork

    TrinketID: 46

    "Consume thy enemy"

    After clearing a room, you have a chance to heal for half a red heart

    *, the lost item pool, silver, metal, grey, gray, isaacs fork

  • A Missing Page

    TrinketID: 48

    "It glows with power"

    When taking damage, Isaac has a chance to deal damage to the entire room in a Necronomicon style effect

    The chance to damage enemies is affected by your luck stat and at +50 or more Luck it will activate 50% of the time

    * , the lost item pool, pink, purple, paper, red

  • Bloody Penny

    TrinketID: 49

    "Wealth of health"

    Everytime you pick up a penny, you have a chance to spawn a red heart on the floor

    UNLOCK: Unlock this item by beating the Chest with Samson

    * , the lost item pool, red, coin, cent, money

  • Burnt Penny

    TrinketID: 50

    "Wealth of chaos"

    Everytime you pick up a coin, you have a 25% chance to spawn a bomb on the floor

    UNLOCK: Unlock this item by beating Challenge #13 (Beans!)

    *, money, silver, grey, gray, steam, smoke, cent

  • Flat Penny

    TrinketID: 51

    "Wealth of answers"

    Everytime you pick up a coin, you have a 25% chance to spawn a key

    *, white, grey, gray, coin, cent, money, cash

  • Counterfeit Penny

    TrinketID: 52

    "Wealth of wealth"

    When picking up a coin, you have a chance to automatically gain one more coin

    UNLOCK: Unlock this item by playing the shell game in the arcade 100 times

    *, yellow, golden, coin, cent, money, cash, sparkle

  • Tick

    TrinketID: 53

    "Well, that's not coming off"

    When you enter a boss room, immediately remove 15% health from the boss and restore 1 red heart

    This trinket can only be removed by using the Smelter item or picking up the Match Stick trinket, meaning you are otherwise unable to take any more trinkets unless you get another item which allows you to hold a second trinket (e.g. Mom's Purse).

    *, insect, bug, spider, beetle, grey, gray, brown

  • Isaac's Head

    TrinketID: 54

    "Dead friend"

    While held, this trinket gives Isaac a familiar that shoots piercing tears that deal 3.5 damage

    UNLOCK: Unlock this item by beating the Boss Rush with Isaac

    *, dead, crying, isaacs head

  • Maggy's Faith

    TrinketID: 55

    "Faith's reward"

    At the start of a new floor, you get an eternal heart

    UNLOCK: Unlock this item by beating the Dark Room with Maggy

    * , the lost item pool, cross, yellow, golden, glow, maggys faith

  • Judas' Tongue

    TrinketID: 56

    "Payment received"

    Items which cost 2 heart containers in a deal with the devil are reduced to only cost 1 heart

    UNLOCK: Unlock this item by beating Satan with Judas

    * , the lost item pool, tong, red, bloody, lips, judas tongue

  • ???'s Soul

    TrinketID: 57

    "Imaginary friend"

    Creates a familiar which moves around the room in a similar fashion to The Peeper, shooting tears in the same direction as Isaac

    UNLOCK: Unlock this item by beating the Dark Room with Blue Baby

    *, dead, baby, blue, ???s soul, blue baby's soul, blue babys soul

  • Samson's Lock

    TrinketID: 58

    "Your rage grows"

    When you kill an enemy, you have a chance to get +0.5 damage up for the current room

    UNLOCK: Unlock this item by beating the Dark Room with Samson

    *, hair, pony, tail, brown, red, samsons lock

  • Cain's Eye

    TrinketID: 59

    "May you see your destination

    Gives a 25% chance to reveal map icons at the start of a new floor (The same effect as the Compass)

    UNLOCK: Unlock this item by beating the Chest with Cain

    *, circle, white, black

  • Eve's Bird Foot

    TrinketID: 60

    "Revenge from beyond"

    When you kill an enemy, you have a chance to spawn a transparent Dead Bird familiar

    The Dead Bird familiar deals 2 damage per tick to enemies while in contact with them

    UNLOCK: Unlock this item by beating the Isaac boss with Eve

    *, grey, gray, black, striped, eves bird foot

  • The Left Hand

    TrinketID: 61

    "The left hand path reaps dark rewards"

    Replaces chest spawns with red chests

    REPENTANCE - No longer replaces chests that have already spawned

    UNLOCK: Unlock this item by beating Ultra Pride

    * northernlion, drop the left hand, paw, bloody, bleeding, grey, gray

  • Afterbirth Trinkets (29)

  • Shiny Rock

    TrinketID: 62

    "It shines for it's brothers"

    While held, tinted rocks and rocks with a crawlspace below them will flash white every 10 seconds

    *, grey, gray, silver, lump, metal, stone

  • Safety Scissors

    TrinketID: 63

    "Fuse cutter"

    Turns all troll bombs into bombs which you can pick up and use

    Super Troll bombs turn into 1+1 free double bomb pickups

    *, blue, metal, sissors

  • Rainbow Worm

    TrinketID: 64

    "Bleep bloop blop"

    Gives your tears a random worm effect every few seconds

    The possible tear effects include: Whip Worm, Ring Worm, Wiggle Worm, Flat Worm, Hook Worm, Pulse Worm, Tape Worm and Lazy Worm

    *, lgbt, circle, snake, red, green, blue

  • Tape Worm

    TrinketID: 65

    "Floooooooooop!"

    While held, Tape Worm doubles your range stat and halves your tear height stat

    *, intestine, white, snake

  • Lazy Worm

    TrinketID: 66

    "Pft"

    -0.4 Shot Speed Down

    +4.0 Range Up

    +2.0 Tear Height

    *, circle, button, eyes, white

  • Cracked Dice

    TrinketID: 67

    "You feel cursed... kinda."

    Every time you get hit, you have a chance to activate the D6, D20, D8 or D12 effect

    UNLOCK: Unlock this item by beating Greed Mode with ???

    *, stone, rock, grey, gray, white, dice, pip, broken, die

  • Super Magnet

    TrinketID: 68

    "It pulls"

    While held this trinket causes all pickups and enemies to move slowly towards you

    Will also attract the Mom's Foot and Ultra Greed door entities

    *, white, grey, gray, pill, medicine, drug

  • Faded Polaroid

    TrinketID: 69

    "You feel faded"

    Randomly Isaac will gain a camouflage for a few seconds and all enemies in the current room will have a confused status effect applied to them

    This trinket can be used to open the door to Mausoleum in Depths II

    *, photo, family, old

  • Louse

    TrinketID: 70

    "Itchy, tasty..."

    Gives a small chance to spawn a friendly attack spider while in a hostile room with enemies

    *, bug, insect, pink, legs

  • Bob's Bladder

    TrinketID: 71

    "Creepy bombs"

    Leaves a pool of green creep under all bombs you place, which damages enemies that walk over it

    *, green, bogey, snot, ocarina, bobs bladder, bob bladder

  • Watch Battery

    TrinketID: 72

    "Lil charge"

    Gives a +6.66% chance of a getting a small battery after clearing a room

    Gives a +2.0% chance for pickups to be small batteries

    Gives a +5.0% chance to add an extra charge to your active item after clearing a room

    *, metal, grey, gray, silver, pill, cross

  • Blasting Cap

    TrinketID: 73

    "Pop! Pop!"

    Exploding bombs now have a chance to drop another bomb that you can pick up

    *, orange, red, circle

  • Stud Finder

    TrinketID: 74

    "The ground below feels hollow..."

    Higher chance to find crawl spaces when exploding rocks

    UNLOCK: Unlock this trinket by beating Challenge #27 (Brains)

    *, toe, finger, thumb, grey, gray, black, red, yellow

  • Error

    TrinketID: 75

    "Effect not found?"

    Gives a different trinket effect per room, randomly choosing between any of the other available trinkets in the game

    Each room is locked to a specific trinket effect, meaning if you exit and re-enter a room, that specific room will always have the same effect.

    *, 404, red

  • Poker Chip

    TrinketID: 76

    "It's double down time!"

    Chests now have a 50/50 chance to either pay out with extra consumables or nothing/an enemy

    UNLOCK: Unlock this trinket by beating Challenge #26 (I Rule)

    *, red, white, circle, pill, bow

  • Blister

    TrinketID: 77

    "Bounce back!"

    Tears have a stronger knockback effect while this trinket is held

    *, white, lump, circle, hairy

  • Second Hand

    TrinketID: 78

    "Extended stat effect time"

    Increases the time that status effects stay on enemies. e.g. With poison effects, the damage over time poison will last for much longer.

    *, red, stick, dynamite, tnt, rod

  • Endless Nameless

    TrinketID: 79

    "I'm stuck in a loop..."

    While held there is a small chance when using a tarot card or pill that a copy of it will be dropped on the floor next to you

    *, grey, gray, black, infinity, oo

  • Black Feather

    TrinketID: 80

    "With darkness comes power"

    +0.2 Damage Up for each 'evil' item you have

    Items classed as evil in this case are Black Candle, Ceremonial Robes, Abaddon, Goat Head, Match Book, Missing Page 2, Safety Pin

    UNLOCK: Unlock this item by beating Greed Mode with Eve

    *, grey, gray, leaf

  • Blind Rage

    TrinketID: 81

    "Blind to damage"

    Invincibility lasts longer after getting hit (Increased i-frames)

    This makes it possible to use the Blood Donation machine twice from one hit of damage

    UNLOCK: Unlock this item by beating Blue Womb (Hush) with Samson

    *, bandana, sling, white, knot, blindfold

  • Golden Horse Shoe

    TrinketID: 82

    "Feel lucky?"

    +15% chance to get a double item room to spawn on the next floor

    If the effect activates, two items spawn in your item room, however only one can be taken (Same effect as the More Options item)

    The chance doubles to +30% with the effect from Mom's Box

    *, yellow, u, magnet

  • Store Key

    TrinketID: 83

    "Stores are open"

    Automatically opens all shop room doors for free

    UNLOCK: Unlock this trinket by donating 666 coins to the Greed Donation Machine

    UNLOCK: Keeper starts with this trinket after beating Satan with Keeper

    * starting, grey, gray, metal

  • Rib of Greed

    TrinketID: 84

    "Feels greedy"

    Forces the Greed and Super Greed mini bosses to no longer appear in shops or secret rooms

    Holding Rib of Greed increase your chance to receive coin drops

    UNLOCK: Unlock this trinket by beating Ultra Greed with Keeper

    *, white, trunk, bent

  • Karma

    TrinketID: 85

    "Karma up"

    Donating to a Donation Machine has a chance to heal Isaac for a full red heart or spawn a Beggar

    UNLOCK: Unlock this item by beating The Lamb boss with Keeper

    *, black, three, spiral

  • Lil Larva

    TrinketID: 86

    "the poop is moving..."

    Destroying poops now gives you a blue fly

    *, white, grey, gray, bent

  • Mom's Locket

    TrinketID: 87

    "you feel her love"

    While held, you heal for half a red heart every time you use a key to open a door or golden chest

    Changes all half red hearts into full hearts

    *, red, brown, grey, gray, necklace, moms locket, mom locket

  • NO!

    TrinketID: 88

    "Never again!"

    While this trinket is held you have a significantly lower chance to find spacebar/active items

    It will cause passive items to spawn except when the game cannot generate any more passive items and will then instead choose spacebar/active items

    Some hard coded spacebar items from bosses and mini-bosses (i.e. Krampus Head) can still spawn

    Bible drops caused by the Rosary item are not prevented by this trinket

    *, stop, red, circle, line, cross, entry, warning

  • Child Leash

    TrinketID: 89

    "Keep your friends close..."

    Causes your familiars to stay closer to each other

    *, ribbon, green, blue

  • Brown Cap

    TrinketID: 90

    "Fartoom!"

    Poop in the environment will now explode when destroyed

    *, circle, rectangle

  • Afterbirth Plus Trinkets (38)

  • Meconium

    TrinketID: 91

    "Eww"

    While held you have an increased chance for Black Poops to spawn, which deal damage to all enemies in the room when destroyed

    Gives The Poop active item a chance to spawn a Black Poop too

    UNLOCK: Unlock this trinket by defeating Greedier Mode with ???

    *, black, grey, gray, poop

  • Cracked Crown

    TrinketID: 92

    "Boost Stats"

    Gives you extra stat upgrades based on the items you've already collected that have stat increases, at +20% of the item's original increase

    REPENTANCE - Reduced Cracked Crown's stat bonuses to +20% (from +33%) and removed the flat independent tears upgrade from it

    *, broken, damaged, yellow, golden

  • Used Diaper

    TrinketID: 93

    "You Stink"

    While held, gives the Skatole effect only in certain rooms, which will turn hostile flies to neutral and stop others from shooting

    Attack, Dart and Ring Flies turn into neutral Black Flies and Pooters and Fat Flies will no longer fire at you

    *, circle, white, fly, brown, poop

  • Fish Tail

    TrinketID: 94

    "It also stinks!"

    Items and trinkets which generate blue flies and spiders will have double the effect, causing twice as many to spawn

    *, grey, gray, green, arrow, flower, plant

  • Black Tooth

    TrinketID: 95

    "It looks dead"

    Some tears will randomly become a black tooth, that deal double your normal tear damage and can poison enemies

    *, grey, gray, horn

  • Ouroboros Worm

    TrinketID: 96

    "Foop foop!"

    Tears become spectral and travel in a large spiral pattern

    +4.0 Range Up

    *, grey, gray, brown, circle, snake

  • Tonsil

    TrinketID: 97

    "Sick..."

    Every time you take damage you have a very small chance to gain a Tonsil familiar, which follows you and blocks enemy projectiles

    This effect can happen twice before the Tonsil trinket is destroyed

    Does not deal contact damage to enemies

    *, pink, bloody, brain

  • Nose Goblin

    TrinketID: 98

    "Seems magic..."

    Your tears have a random chance to become booger tears

    Booger tears stick on to enemies and deal periodic poison damage until they die or 60 seconds passes. Each tick of poison damage is equal to your normal tear damage

    The boogers will have a homing effect

    *, green, snot, booger, bogey, slime

  • Super Ball

    TrinketID: 99

    "Boing!"

    Some random tears will gain the Rubber Cement effect and become bouncy

    *, yellow, orange, red, circle, stripe

  • Vibrant Bulb

    TrinketID: 100

    "It needs power"

    Grants +0.25 Speed, +0.75 Range, +0.1 Shot Speed, +0.2 Tears, +0.5 Damage and +1 Luck when Isaac's active item is fully charged

    Infinite use items such as Potato Peeler count as charged and provide the bonus from this trinket

    *, yellow, light

  • Dim Bulb

    TrinketID: 101

    "I think it's broken"

    Grants +0.5 Speed, +1.5 Range, +0.3 Shot Speed, +0.4 Tears, +1.5 Damage when Isaac's active item is completely uncharged

    One-time use items such as Mama Mega count as uncharged and provide the bonus from this trinket

    *, grey, gray, light

  • Fragmented Card

    TrinketID: 102

    "Double moon"

    Gives you another secret room on each new floor while held

    Does not spawn more than one super secret room, only the normal secret room

    *, purple, torn, ripped, paper, page, poster

  • Equality!

    TrinketID: 103

    "="

    When you have the same amount of coins, bombs and keys, half consumables turn into their doubled version

    This effect works for any number of consumables, including 0 and 99, as long as the count for coins/keys/bombs is equal

    *, red, lines, redpill

  • Wish Bone

    TrinketID: 104

    "Make a wish"

    Every time you take damage you have a very small chance to spawn a random pedestal item

    When the effect triggers, the trinket is destroyed

    *, grey, gray, claw, rib

  • Bag Lunch

    TrinketID: 105

    "I wonder what it is"

    Every time you take damage you have a very small chance to spawn the Lunch item, which gives +1 HP up

    When the effect triggers, this trinket is destroyed

    *, brown, sack, hoof

  • Lost Cork

    TrinketID: 106

    "Uncorked"

    Increases the radius of any creep you produce

    *, brown, yellow, orange, black

  • Crow Heart

    TrinketID: 107

    "Drain me"

    While held, any damage taken will ignore soul hearts and black hearts, causing your red heart containers to be depleted first

    While at 1/2 of a red heart, it will begin to remove your soul hearts and black hearts on damage again

    UNLOCK: Unlock this item by beating Greedier mode with Eve

    * crow's, purple, blue, bloody

  • Walnut

    TrinketID: 108

    "Thats a hard nut to crack!"

    The Walnut has a chance to break when taking damage from an explosion. If it does, it will drop a random trinket, coin, heart and key

    The Walnut trinket is destroyed once the effect activates

    *, brown, brain, stone, rock

  • Duct Tape

    TrinketID: 109

    "Stuck!"

    Causes any orbitals you have to stop moving while held

    Stops shooting familiars from moving (including Lilith's Incubus)

    Some familiars with irregular movement are not affected by Duct Tape, such as Abel, BBF, Bumbo, Guppy's Hair Ball, Lil Gurdy, Punching Bag, Robo-Baby 2.0, Succubus

    *, grey, gray, tp, toilet, paper, roll, silver

  • Silver Dollar

    TrinketID: 110

    "Feels lucky..."

    While held, shops will now appear on the womb floors (The Womb, Utero and Scarred Womb)

    UNLOCK: Unlock this item by defeating Delirium in The Void floor with Cain

    *, coin, money, cash, cent

  • Bloody Crown

    TrinketID: 111

    "Drips with blood..."

    While held, item rooms now appear on the womb floors (The Womb, Utero and Scarred Womb)

    REPENTANCE - Causes item rooms to appear on Corpse floors

    UNLOCK: Unlock this item by defeating Delirium in The Void floor with Samson

    *, red, dripping

  • Pay To Win

    TrinketID: 112

    "..."

    While held, restock boxes will always spawn in item rooms

    *, cent, money, cash, coin, pixel, blue, green, p2w

  • Locust of War

    TrinketID: 113

    "I Bring Wrath"

    Upon entering a room with enemies, spawns a Red Locust which detonates upon impact with enemies, dealing double tear damage for the impact of the Locust and 60 damage for the explosion

    Can be dangerous as the fly will target the nearest enemy, which can be close enough to catch Isaac in its blast radius

    UNLOCK: Unlock this trinket by defeating Isaac in the Cathedral as Apollyon

    *, red, wings, fly, locust of wrath

  • Locust of Pestilence

    TrinketID: 114

    "I Bring Pestilence"

    At the start of each new hostile room you spawn a green attack fly, which will target a nearby enemy, deal double your tear damage and then poison them

    UNLOCK: Unlock this item by beating Satan with Apollyon

    *, green, wings, fly

  • Locust of Famine

    TrinketID: 115

    "I bring Famine"

    At the start of each new hostile room you spawn a yellow attack fly, which will target a nearby enemy, deal double your tear damage and apply a slowing effect to it

    UNLOCK: Unlock this trinket by defeating ??? in The Chest as Apollyon

    *, brown, wings, fly

  • Locust of Death

    TrinketID: 116

    "I bring Death"

    Upon entering a room with enemies, spawns a Black Locust that deals quadruple Isaac's damage, applied as two hits of double damage

    UNLOCK: Unlock this trinket by defeating The Lamb as Apollyon

    *, grey, gray, black, wings, fly

  • Locust of Conquest

    TrinketID: 117

    "I Bring Conquest"

    At the start of each new hostile room you spawn 2-5 white attack flies, which will target a nearby enemy and deal double your tear damage to it

    UNLOCK: Unlock this trinket by defeating Boss Rush as Apollyon

    *, white, wings, fly

  • Bat Wing

    TrinketID: 118

    "They Are Growing..."

    When killing an enemy, you have a very small chance to gain the ability to fly for the rest of the room

    UNLOCK: Unlock this trinket by defeating Greedier Mode with Azazel

    *, black, grey, gray

  • Stem Cell

    TrinketID: 119

    "Regen!"

    Heals you for 1/2 a red heart after travelling down to the next floor

    UNLOCK: Unlock this trinket by defeating Greedier Mode with Samson

    *, red, pink, orange, eye, circle

  • Hairpin

    TrinketID: 120

    "Poke that power outlet! Bosses charge you"

    Fully recharges your active item at the start of each boss fight

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Zaratus

    *, yellow, whip, glow, black

  • Wooden Cross

    TrinketID: 121

    "My faith protects me"

    Gives you the Holy Mantle shield effect at the start of every new floor, which protects you from the next hit of damage you take

    Does not recharge until the start of the next floor

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Ep and Mills

    *, brown, crucifix

  • Butter!

    TrinketID: 122

    "Can't hold it!"

    Using your active item while holding this trinket will drop it back on a pedestal on the ground

    Also after taking damage, you have a very small chance to drop one of your passive items

    One-time use active items will be consumed and not dropped

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by MarkusLeben and iguesti

    *, yellow, golden, box, block, square, cube

  • Filigree Feather

    TrinketID: 123

    "Angelic spoils!"

    Holding this trinket will cause the Angel mini bosses to drop normal items instead of Key Pieces

    Added as part of the Afterbirth+ Booster Pack #2, designed by Edmund McMillen

    *, silver, grey, gray, white, quill

  • Door Stop

    TrinketID: 124

    "Hold the door!"

    While held, the last door Isaac went through stays open, allowing him to leave the room even if enemies are in it

    This trinket works on boss rooms (except Ultra Greed) and devil rooms containing Krampus, allowing you to exit out mid-fight

    *, door, stop, wedge, cheese, wood, brown, hodor, game of thrones, Wylis

  • Extension Cord

    TrinketID: 125

    "Charged friends"

    After being picked up, a yellow laser chain now flows through Isaac's familiars

    Added as part of the Afterbirth+ Booster Pack #4 and based on the Steam Workshop mod created by Strawrat and Aczom

    *,

  • Rotten Penny

    TrinketID: 126

    "Wealth of flies"

    While held, spawns +1 friendly blue fly every time you pick up a coin

    Added as part of the Afterbirth+ Booster Pack #5. Based on the Steam Workshop mod created by Eufuu

    UNLOCK: Unlock this trinket by having a lot of blue flies at once

    *,

  • Baby-Bender

    TrinketID: 127

    "Feed them magic!"

    While held this trinket gives your familiars homing shots

    Added as part of the Afterbirth+ Booster Pack #5. Based on the Steam Workshop mod created by Ink Tears

    UNLOCK: Unlock this item by having two items or effects that grant homing shots at once (e.g. Spoon Bender, Telepathy for Dummies, I - The Magician)

    *, baby bender babybender

  • Finger Bone

    TrinketID: 128

    "It looks brittle"

    While held, gives you a small chance to gain a bone heart everytime you take damage

    Added as part of the Afterbirth+ Booster Pack #5

    REPENTANCE - Finger Bone's chance to grant a bone heart has been increased to 5% per hit taken (from 2%)

    UNLOCK: Unlock this trinket by defeating Ultra Greed as The Forgotten

    *,

  • Consumables + Misc.

  • O - The Fool

    "Where your journey begins"

    Teleports the player to the first room of the current floor

    There is a guaranteed Fool card in the Depths 2, if you bomb the skull with an X on it. This is intended give you a guaranteed way to teleport out of the Mom's Foot fight, for accessing the path to the Mausoleum floor

    *, tarot, card, green

  • I - The Magician

    "May you never miss your goal"

    For the current room, tears now have the Spoon Bender effect, which allows them to curve towards enemies and gives them a purрle appearance.

    *, tarot, card, yellow

  • II - The High Priestess

    "Mother is watching you"

    Summons Mom's foot which will stomp on a random enemy in the current room, dealing 300 damage

    If no enemies are in the current room, the foot will target Isaac (and do damage if it hits), however it can be used to break rocks

    *, tarot, card, red

  • III - The Empress

    "May your rage bring power"

    Gives the player the Whore of Babylon effect for the current room, increasing damage and speed

    * speed up, tarot, card, blue, red

  • IV - The Emperor

    "Challenge me!"

    Teleports the player to the Boss room on the current floor

    *, tarot, card, yellow

  • V - The Hierophant

    "Two prayers for the lost"

    Spawns 2 Soul hearts on the floor

    *, the lost item pool, tarot, card, blue, red

  • VI - The Lovers

    "May you prosper and be in good health"

    Spawns 2 red hearts on the floor

    * , the lost item pool, tarot, card, red

  • VII - The Chariot

    "May nothing stand before you"

    Grants the same effect as 'My Little Unicorn', which makes Isaac invincible and deal 40 contact damage to enemies per hit

    *, tarot, card, yellow

  • VIII - Justice

    "May your future become balanced"

    Spawns 1 bomb, 1 key, 1 coin, 1 heart, which can be random variants of each

    *, tarot, card, red

  • IX - The Hermit

    "May you see what life has to offer"

    Teleports the player to the Shop

    On or below the Womb, this acts as a random teleport, since there are no shops on those floors

    *, tarot, card, blue

  • X - Wheel of Fortune

    "Spin the wheel of destiny"

    Spawns a Slot Machine or a Fortune Machine

    *, tarot, card, pink

  • XI - Strength

    "May your power bring rage"

    Gives the player the Magic Mushroom effect, which increasing size and all stats by 1 for the current room

    If you use the Strength card with 12 heart containers, it will take you down to 11 when you leave the room

    *, tarot, card, pink

  • XII - The Hanged Man

    "May you find enlightenment"

    Gives the player the flying effect for the current room, allowing the player to fly over obstacles in the room

    This card is useless if you have any item which allows you to permanently fly

    * , the lost item pool, tarot, card, grey, gray

  • XIII - Death

    "Lay waste to all that oppose you"

    Deals 40 damage to all enemies in the room in a similar style to the Necronomicon

    *, tarot, card, grey, gray

  • XIV - Temperance

    "May you be pure in heart"

    Spawns a Blood Donation Machine

    * , the lost item pool, tarot, card, red, blue

  • XV - The Devil

    "Revel in the power of your darkness"

    Gives the Book of Belial effect for the current room, increasing damage

    * damage up, tarot, card, red

  • XVI - The Tower

    "Destruction brings creation"

    Spawns some troll bombs at random locations in the current room

    Each bomb deals 60 damage (normal bomb damage

    *, tarot, card, purple

  • XVII - The Stars

    "May you find what you desire"

    Teleports the player to the Item Room

    On or below the Womb, this acts as a random teleport, since there are no item rooms on those floors

    *, tarot, card, blue

  • XVIII - The Moon

    "May you find all you have lost"

    Teleports the player to the Secret Room

    *, tarot, card, blue

  • XIX - The Sun

    "May the light heal and enlighten you"

    A card with three uses: A full heal, deals 100 damage to all enemies in the current room and reveals the entire map for the current floor (Treasure Map + The Compass)

    *, tarot, card, yellow

  • XX - Judgement

    "Judge lest ye be judged"

    Spawns a beggar

    Has a chance to be a demon beggar

    Killing a Devil Beggar, Key Master, or Shell Game Beggar gives you an increased chance of finding Angel rooms instead of Devil rooms. See the dedicated Devil room page for more details

    *, tarot, card, blue

  • XXI - The World

    "Open your eyes and see"

    Reveals the entire map and shows the icons for every room which has one

    This is completely useless if you currently have both the Treasure Map and The Compass

    *, tarot, card, pink

  • 2 of Spades

    "Item multiplier"

    Doubles the number of keys you have

    If you have no keys, it gives you two

    *, playing, card, white, black

  • 2 of Clubs

    "Item multiplier"

    Doubles the number of Bombs you have

    If you have no bombs, it gives you two

    *, playing, card, white, black

  • 2 of Hearts

    "Item multiplier"

    Doubles your current red hearts up to full health

    This card is useless for the Bluе Baby

    * , the lost item pool, playing, card, white, red

  • 2 of Diamonds

    "Item multiplier"

    Doubles the number of coins you have

    If you have no coins, it gives you two

    *, playing, card, white, red

  • The Joker

    "???"

    Teleports you to the Devil Deal Room on the current floor

    *, playing, card, white, black

  • Chaos Card

    "???"

    A card which can be thrown as a projectile directly infront of Isaac, instantly killing anything it hits, including most bosses

    If thrown at a multi-phase boss with multiple forms such Satan, Mega Satan or Hush it will only kill that particular phase of the boss

    If thrown at a multi-phase boss that works from a single health bar such as Isaac, ??? or The Lamb, it will die instantly

    Will not kill Delirium of The Beast

    Will destroy rocks and poop in its path

    Can also be thrown against a door to open it (Doesn't work against Mega Satan's door)

    UNLOCK: Unlock this card by beating Challenge #9 (Demo Man)

    *, mtg, card, magic, gathering, brown

  • Credit Card

    "Charge it!"

    When used, removes the price tag from all items in the current shop or devil deal, making everything free

    The effect of the Credit Card only lasts for the current room

    UNLOCK: Unlock this card by beating Challenge #10 (Cursed!)

    *, blue, green

  • Rules Card

    "???"

    Displays a random cryptic message on the screen similar to the fortune machine ones. One of the following messages may show:

    "Rooms may yield more than you expect"

    "Some doors require a blessing. Carry them with you"

    "The walls will harden over time. Time is the essence"

    "Sleeping gatekeepers will need to be awoken with a loud sound"

    "A piece of paper is your guide"

    "Deny his gifts to attain your reward"

    "A dark market lies under your feet

    "Chub dislikes smoke!

    UNLOCK: Unlock this card by beating Challenge #11 (Glass Cannon)

    *, white, black, writing

  • Card Against Humanity

    "Something stinks..."

    When used, fills the entire room with poop!

    UNLOCK: Unlock this card by beating Challenge #12 (When Life Gives You Lemons)

    *, black, white, writing

  • Suicide King

    "A true ending?"

    When used, instantly kills you and spawns 10 pickup on the floor

    Each of the 10 things spawned can be any type of consumable or sometimes a pedestal item (up to a maximum of 3 pedestal items)

    Any pedestal item created by Suicide King will be related to the room where it was used, meaning that using it in the Angel room will spawn Angel room items

    UNLOCK: Unlock this card by beating Challenge #7 (Suicide King)

    *, white, blue, red

  • Rune of Algiz

    "Resistance"

    When used, gives you an invincibility effect which lasts for 20 seconds

    UNLOCK: Unlock this card by beating Challenge #8 (Cat Got Your Tongue)

    *, purple, glow

  • Rune of Ansuz

    "Vision"

    When used, reveals the entire map including all the secret room locations and other icon rooms

    UNLOCK: Unlock this card by beating Challenge #5 (The Tank)

    *, purple, glow

  • Rune of Berkano

    "Companionship"

    Summons 3 blue friendly spiders and 3 blue flies

    UNLOCK: Unlock this card by beating Challenge #20 (Purist)

    *, purple, glow

  • Rune of Dagaz

    "Purity"

    Removes the curse which is in effect on the current floor (except Curse of the Labyrinth)

    Can also cure the effect of the Amnesia pill

    +1 Soul Heart

    UNLOCK: Unlock this card by beating Challenge #4 (Darkness Falls)

    *, purple, glow

  • Rune of Ehwaz

    "Passage"

    Creates a trapdoor on the floor

    Has a 8% chance to spawn a door to a Crawl Space instead

    UNLOCK: Unlock this card by beating Challenge #3 (Head Trauma)

    *, purple, glow

  • Rune of Hagalaz

    "Destruction"

    When used, this rune will destroy all breakable objects in the current room, such as poop, rocks, secret room entrances

    This includes Key Blocks

    UNLOCK: Unlock this card by beating Challenge #1 (Pitch Black)

    *, purple, glow

  • Rune of Jera

    "Abundance"

    When used this rune will double all pickups on the floor in the room

    Creates copies of pickups in the Shop which can be taken for free, even if you haven't purchased them yet

    Can be used to double the number of item chests in the first room of the final Chest / Dark Room floors

    Cloned chests have the same types of items as the first one

    Cannot be used to clone trinkets or other Jera runes

    UNLOCK: Unlock this card by beating Challenge #2 (High Brow)

    *, purple, glow

  • Rune of Perthro

    "Change"

    Rerolls all pedestal items in the current room (One time use of the D6)

    UNLOCK: Unlock this card by beating Challenge #6 (Solar System)

    *, purple, glow

  • Dice Rooms

    1 Dot - Rerolls all of your items. (Does not change your trinkets, pills or cards)

    2 Dot - Rerolls all pickups in the room. (D20 effect)

    3 Dot - Rerolls all pickups on the entire floor

    4 Dot - Rerolls all pedestal items on the floor. (Does not roll your devil deal items)

    5 Dot - Reroll and restart the current floor (Forget Me Now effect)

    6 Dot - Reroll all of your items and all the pickups on the entire floor (Combined 1 + 3 + 4 rooms)

    * pip

  • Blank Rune

    "???"

    When used, gives a random Mystic rune effect

    Possible effects include: Algiz, Ansuz, Berkano, Dagaz, Ehwaz, Hagalaz, Jera, Perthro

    Also has a 25% chance to spawn another Blank Rune upon use

    UNLOCK: Unlock this card by beating Challenge #30 (Guardian)

    *

  • Dice Shard

    Gives a one-time use of the D6 and D20 effects at the same time

    *, purple, broken, pip

  • Get Out Of Jail Free Card

    "Open sesame"

    When used, will open all doors in the current room, similar to a one-time use of Dad's Key

    UNLOCK: Unlock this card by beating Challenge #22 (Speed)

    *, brown, orange

  • ? Card

    "Double active"

    When used this card will activate a use of your spacebar item for free

    *, black, white, question, mark

  • Emergency Contact

    "Help from above"

    When used will cause two of Mom's Hand to come down and grab a random enemy

    *, mom, brown, paper, shop room pool

  • Gold Key

    Once picked up, you gain unlimited key use for the rest of the floor

    *, yellow, skull

  • Gold Heart

    Once picked up, the gold heart will drop money on the floor the next time Isaac loses a heart

    UNLOCK: Unlock this item by beating challenge #21 (XXXXXXXXL)

    *, yellow heart, golden heart

  • Bone Heart

    Takes three hits to deplete and can be refilled with red hearts, but disappears forever when depleted

    UNLOCK: Unlock this item by unlocking the Forgotten character. See the Broken Shovel / Mom's Shovel items for more information on how to unlock

    *, bone heart, white heart

  • Gold Bomb

    Once picked up, you gain unlimited bomb use for the rest of the floor

    UNLOCK: Unlock this item by beating challenge #23 (Blue Bomber)

    *, yellow

  • Ace of Hearts

    "Convert all"

    When used, turns all pickups, chests and non-boss enemies in the room into Hearts

    UNLOCK: Unlock this item by defeating any floor after Basement I with only half a heart of health (works as The Lost)

    *, playing, card, white, red

  • Ace of Spades

    "Convert all"

    When used, turns all pickups, chests and non-boss enemies in the room into Keys

    UNLOCK: Unlock this item by defeating The Lamb without taking hearts, coins and bombs

    *, playing, card, white, black

  • Ace of Clubs

    "Convert all"

    When used, turns all pickups, chests and non-boss enemies in the room into Bombs

    UNLOCK: Unlock this item by getting a 3 win streak

    *, playing, card, white, black

  • Ace of Diamonds

    "Convert all"

    When used, turns all pickups, chests and non-boss enemies in the room into Coins

    UNLOCK: Unlock this item by defeating The Lamb in under 20 minutes

    *, playing, card, white, red

  • Holy Card

    "You feel protected"

    Grants the Holy Mantle effect for, which will negate your next hit of damage

    The effect persist between rooms/floors

    Tainted Lost starts with this card, and while playing as this character all cards and runes have a 10% chance to turn into a Holy Card

    UNLOCK: Unlock this item by defeating Delirium in The Void floor with The Lost

    *, playing, card, white, cross, blue

  • Black Rune

    "Void"

    When used, this rune deals 40 damage to all enemies in the room and consumes all pedestal items in the room, giving you a random stat increase for each item consumed

    Also consumes all pickups in the room and turns them into blue flies and spiders

    UNLOCK: Unlock this item by beating Greedier mode as Apollyon

    *, rock, black

  • Huge Growth

    "Become immense!"

    Temporarily makes Isaac huge, giving him +7 Damage Up and +30 Range Up for the rest of the current room

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Coper140

    UNLOCK: Unlock this item by getting 5 items or consumables that increase your size, e.g. 'One Makes you Larger' pills, Magic Mushroom etc

    *, mtg, card, magic, gathering, green, brown, giant growth

  • Ancient Recall

    "Draw 3 cards"

    Spawns 3 random cards on the floor when used

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Coper140

    *, mtg, card, magic, gathering, blue

  • Era Walk

    "Savor the moment"

    When used, this card will slow down enemies, Isaac's tears by -1 Shot Speed, but speed up Isaac's movement speed by +0.50 for the rest of the current room

    Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Coper140

    UNLOCK: Unlock this item by getting both the Broken Watch and the Stop Watch in your collection

    *, mtg, card, magic, gathering, blue

  • Rebirth Pills A - L (Page 1 of 2)

    48 Hour Energy - Fully recharges your active item and drops 1-2 battery pickups. Can be used with Placebo to generate infinite batteries

    Amnesia - Hides the floor map for the rest of the current floor (same as curse of the lost). Can be negated with Black Candle

    Bad Gas - Isaac farts, poisoning enemies around him

    Bad Trip - Deals damage to yourself

    Balls of Steel - +2 Soul Hearts

    Bombs are key - Switches number of bombs and keys

    Explosive Diarrhea - Spawns five live troll bombs behind Isaac, one per second

    Full Health - Restores all your empty red heart containers

    Health Down - -1 HP. If you have 1 or less heart containers, this pill becomes Health Up

    Health Up - +1 HP

    Hematemesis - Empties all but one red heart container and spawns 1-4 red hearts on the floor. Spawns coins as The Keeper

    I can see forever - Opens secret room and super secret room entrances on the current floor

    I found pills - Changes the appearance of Isaac's face for the current room (Cosmetic change only)

    Lemon Party - Spawns a large yellow pool on the floor around you, damaging enemies which walk in it

    Luck Down - Reduces your luck stat by -1

    Luck Up - Increases your luck stat by +1

    *

  • Rebirth Pills P - Z (Page 2 of 2)

    Paralysis - Prevents you from moving for a short while

    Pheromones - Applies the charm effect to all enemies in the room for a short while

    Puberty - Causes Isaac to grow hair for the rest of the run. Cosmetic change only. In Afterbirth+, taking 3 of this pill gives the Adult transformation

    Pretty Fly - Gives Isaac +1 fly orbital, which blocks enemy projectiles and damages fly-type enemies on touch

    Range Down - Reduces your range stat by -2

    Range Up - Increases your range stat by +2.5

    R U a wizard? - Tears will shoot diagonally for about 60 seconds. Effect persists between rooms while the time period is active

    Speed Down - Reduces your speed stat by -0.12

    Speed Up - Increases your speed stat by +0.15

    Tears Down - Reduces your tears stat by -0.28

    Tears Up - Increases your tears stat by 0.35

    Telepills - Teleports you to a random room when used. Has a small chance to take you to the I AM ERROR room, and a smaller chance to teleport to a Black Market

    *

  • Afterbirth Pills

    Addicted - Causes you to take a full heart of damage for all sources for the current room. Unlocked from Challenge #24 - PAY TO PLAY

    Friends till the end - Spawns three friendly blue attack flies

    Infested! - Destroys all poops in the room and spawns a blue attack spider on every destroyed poop

    Infested? - Spawns one blue attack spider for every enemy in the room. If there are no enemies this pill spawns 1-3 blue spiders instead

    One makes you smaller - Reduces Isaac's size and hitbox size

    One makes you larger - Increases Isaac's size, but does not affect the size of his hitbox

    Percs - Causes Isaac to only take half a heart of damage from all sources for the current room (The Wafer effect). Unlocked from Challenge #24 - PAY TO PLAY

    Power Pill - Gives you invulnerability and the ability to damage enemies for a short while (similar to The Gamekid effect)

    Re-Lax - Causes Isaac to spawn poops behind him while he walks for a few seconds. Similar to Explosive Diarrhea but with poop

    Retro Vision - Pixelates the screen for a few seconds, obscuring your vision. Happens a total of 3 times over 30 seconds

    ??? - Gives the curse of the maze effect for the current floor. Unlocked from Challenge #25 - Have a Heart

    *

  • Afterbirth+ Pills

    Feels like I'm walking on sunshine! - Turns Isaac invincible for a few seconds (similar to Unicorn Stump). Unlocked from the 'Sin Collector' achievement (collect every Bestiary entry)

    Gulp! - When used will consume your current trinket, destroying it and giving you its effect permanently. Unlocked from the 'Once more with the feeling!' achievement (complete a victory lap, defeating the lamb boss)

    Horf! - When used, shoots an Ipecac explosive shot. Unlocked from the 'Dedication' achievement (participate in 31 dailies in a row)

    I'm Drowsy... - Slows all enemies for the rest of the current room

    I'm excited!!! - Speeds up all enemies for the rest of the room. The effect triggers again 30 seconds after use and again 60 seconds after use

    Something's wrong... - Spawns a pool of black creep beneath Isaac

    Vurp! - Spawns the last pill you used. Spawns another Vurp! pill if no other pills were used yet. Unlocked from the 'U broke it!' achievement (collect 50 items in a single run)

    X-Lax - Spawns a pool of slippery brown creep beneath Isaac

    *

  • O - The Fool?

    "Let go and move on"

    Drops all hearts on the floor leaving you at half a red heart. Dropped hearts may become other pickups like bombs/keys, or even pickup-related items like A Quarter or Boom!

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Lost

    *, tarot, card, green

  • I - The Magician?

    "May no harm come to you"

    Gives you a blue aura that repels enemy projectiles, causing them to slowly curve away from Isaac and avoid hitting him

    Lasts for 60 seconds

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Judas

    *, tarot, card, yellow

  • II - The High Priestess?

    "Run"

    Causes Mom's Foot to keep stomping down randomly for 60 seconds where Isaac is standing

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Lilith

    *, tarot, card, red

  • III - The Empress?

    "May your love bring protection"

    Gives 2 HP Up and +1.5 Tears Up for 60 seconds

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Eve

    * speed up, tarot, card, blue, red

  • IV - The Emperor?

    "May you find a worthy opponent"

    Teleports you to an extra boss room, that drops a Boss room item as normal. This room isn't part of the actual floor, and leaving it returns you to where you teleported from

    The boss isn't necessarily from the current floor - e.g. you could find a caves boss in the basement

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted ???

    *, tarot, card, yellow

  • V - The Hierophant?

    "Two prayers for the forgotten"

    Spawns 2 Bone hearts on the floor

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Bethany

    *, the lost item pool, tarot, card, blue, red

  • VI - The Lovers?

    "May your heart shatter to pieces"

    Spawns a random pedestal item from the current room's item pool

    In exchange, turns one heart container into a broken heart. Broken hearts permanently subtract from your total possible health containers

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Magdalene

    * , the lost item pool, tarot, card, red

  • VII - The Chariot?

    "May nothing walk past you"

    Isaac turns to stone and can't move for 10 seconds, but your tear rate goes up significantly for the duration

    UNLOCK: Unlock this card by defeating challenge #42 (Hot Potato)

    *, tarot, card, yellow

  • VIII - Justice?

    "May your sins come back to torment you"

    Spawns 2-4 locked gold chests

    UNLOCK: Unlock this card by defeating challenge #43 (Cantripped)

    *, tarot, card, red

  • IX - The Hermit?

    "May you see the value of all things in life"

    When used, all items and pickups in the current room are turned into money. Everything is sold for its shop price, e.g. Items for 15c, hearts for 3c

    UNLOCK: Unlock this card by defeating challenge #44 (Red Redemption)

    *, tarot, card, blue

  • X - Wheel of Fortune?

    "Throw the dice of fate"

    Activates a random effect from a Dice room

    See the dice icon above for each possible effect

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Cain

    *, tarot, card, pink

  • XI - Strength?

    "May you break their resolve"

    All enemies in the current room are slowed and take double damage

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Samson

    *, tarot, card, pink

  • XII - The Hanged Man?

    "May your greed know no bounds"

    You turn into the Keeper, gaining triple shot, -0.1 Speed Down for 30 seconds

    Enemies drop random coins while this effect is active

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Keeper

    * , the lost item pool, tarot, card, grey, gray

  • XIII - Death?

    "May life spring forth from the fallen"

    Activates the Book of the Dead effect, spawning a bone orbital or charmed Bony for each enemy killed in the current room

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Forgotten

    *, tarot, card, grey, gray

  • XIV - Temperance?

    "May your hunger be satiated"

    When used, this card activates 5 random pill effects one after the other

    UNLOCK: Unlock this card by defeating challenge #45 (DELETE THIS)

    * , the lost item pool, tarot, card, red, blue

  • XV - The Devil?

    "Bask in the light of your mercy"

    Activates The Bible effect (granting flight) and gives a Seraphim familiar for 30 seconds

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Azazel

    * damage up, tarot, card, red

  • XVI - The Tower?

    "Creation brings destruction"

    Fills the room with random rocks, pots and other objects, creating a maze between the doors

    It won't block any doors that exist

    Rocks have a pretty good chance to become tinted rocks

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Apollyon

    *, tarot, card, purple

  • XVII - The Stars?

    "May your loss bring fortune"

    Removes your oldest passive item and spawns 2 pedestal items from the current room's pool

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Isaac

    *, tarot, card, blue

  • XVIII - The Moon?

    "May you remember lost memories"

    Teleports you to the ultra secret room on the floor

    The ultra secret room is a red room containing an item from the angel room item pool. Can only be accessed via the Red Key, Crystal Key or Cracked Key. Using this card will also open a pathway of red rooms back to the regular floor

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Jacob

    *, tarot, card, blue

  • XIX - The Sun?

    "May the darkness swallow all around you"

    When used, grants +1.5 Damage Up, turns your hearts to Bone hearts and the Spirit of the Night effect (Spectral tears and the ability to fly) for the current floor

    Also gives the Curse of Darkness effect that can't be removed for the current floor

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Jacob

    *, tarot, card, yellow

  • XX - Judgement?

    "May you redeem those found wanting"

    Spawns a beggar

    Spawns a Restock machine

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Lazarus

    *, tarot, card, blue

  • XXI - The World?

    "Step into the abyss"

    Creates a trapdoor to a guaranteed crawl space

    UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Eden

    *, tarot, card, pink

  • Rune Shard

    "It still glows faintly"

    Activates a random rune effect. The effect is weaker than normal runes.

    These only appear if not all runes have been unlocked yet.

    *, shart

  • Cracked Key

    "???"

    This is a one-time use of the Red Key item.

    The main purpose of the Cracked Key is to unlock Tainted character in the Home floor without needing to find the Red Key. You can force spawn a cracked key by droping any trinket in a Boss Room or Item room, on any floor on your way down to Depths II. When you take the reverse path back up to Home, the trinket will turn into Cracked Key in the same floor/room you dropped it before.

    UNLOCK: Unlock this card by opening Mom's Box on the Home floor.

    *, Red Key Shard

  • Queen of Hearts

    "<3"

    Drops 1-12 full red hearts on the floor

    UNLOCK: Unlock this card by defeating Mega Satan as Tainted Magdalene

    *,

  • Wild Card

    "Again"

    When used, this copies the effect of the card, pill, rune, soul stone or active item you used most recently

    UNLOCK: Unlock this card by defeating Mega Satan as Tainted Eden

    *, Uno Card

  • Soul of Isaac

    "Reroll... or not"

    Turns all pedestal items in the current room into rotating items, which cycle between the old item and a random new item every second

    This allows you to effectively reroll items like with The D6, but choose the old item as well if you want

    Tainted Isaac has this effect passively for all items

    If you use more than one in the same room, each pedestal item will cycle through +1 random item

    Items are chosen from the item pool related to the current item

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Isaac

    * Soul Stone

  • Soul of Magdalene

    "Give me your love!"

    When used, all enemies in the current room drop half a red heart that will disappear after 2 seconds if not picked up

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Magdalene

    * Soul Stone

  • Soul of Cain

    "Opens the unopenable"

    When used, this Soul Stone creates Red rooms for every possible exit in the current room

    Red outlines of doors appear where this Soul Stone will create exits for

    See the Red Key item description for more information about these Red rooms behave

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Cain

    * Soul Stone

  • Soul of Judas

    "Right behind you"

    Activates the Dark Arts item effect, which turns Isaac into a ghost for a few seconds. While in this form you can walk over enemies to mark them for death. After a few seconds, he will quickly attack each target, chaining higher damage for each enemy it hits

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Judas

    * Soul Stone

  • Soul of ???

    "Chemical warfare"

    When used this will cause 8 poison farts that leave a brown creep behind, and then drop 7 Butt Bombs very quickly

    Standing in the creep gives you +1 Damage Up and +1.35 Tears Up

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Blue Baby

    * Soul of Blue Baby

  • Soul of Eve

    "Your very own murder"

    For the current room, 14 Dead Birds fly in from off the screen and attack all enemies, dealing low but frequent damage

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Eve

    * Soul Stone

  • Soul of Samson

    "Slay a thousand"

    Isaac gains the Berserk! effect for 10 seconds. This gives Isaac a bone sword and he goes on a killing rampage, gaining +0.4 Speed, +3 Flat Damage Up

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Samson

    * Soul Stone

  • Soul of Azazel

    "Demon rage!"

    Activates the Mega Blast item effect, which gives you a giant laser that deals x5 your tear damage per tick to anything in its path and pushing Isaac back by the force

    The effect lasts for 8 seconds but does persist between rooms

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Azazel

    * Soul Stone

  • Soul of Lazarus

    "Life after death"

    When used this kills Isaac and revives him with 1/2 a red heart. You get a couple of seconds of invincibility to move away after

    The main benefit of this Soul Stone is that it automatically activates if you die, meaning it is effectively an extra passive life while held

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Lazarus

    * Soul Stone

  • Soul of Eden

    "Embrace chaos"

    Activates the D6 and D20 effects, rerolling all items and pickups in the room. Unlike the regular D6, rerolled items can pick from any item pool

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Eden

    * Soul Stone

  • Soul of the Lost

    "Leave your body behind"

    When used, Isaac dies and becomes The Lost for the current room. This gives you his ability to fly, and the Holy Mantle effect. However if you take damage a second time you die like the Lost does

    Same effect as touching a white fire, but only lasts one room

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Lost

    * Soul Stone

  • Soul of Lilith

    "Motherhood"

    Gives you 1 random permanent familiar

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Lilith

    * Soul Stone

  • Soul of the Keeper

    "$$$"

    Spawns up to 25 random coins on the floor

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Keeper

    * Soul Stone

  • Soul of Apollyon

    "Bringer of calamity"

    Creates 15 random Locusts

    Locusts are variants of blue flies, except they have special effects based on the color

    War (Red) - Explodes when touching the enemy. The actual explosion deals flat 60 damage

    Pestilence (Green) - Poisons the enemy it attacks

    Famine (Brown) - Applies a slowing effect

    Death (Black) - Deals x4 damage instead of x2

    Conquest (White) - Spawns 2-5 at once

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Apollyon

    * Soul Stone

  • Soul of the Forgotten

    "Skeletal protector"

    Gives you The Forgotten as a temporary familiar, with 2 Bone hearts and his bone weapon. He behaves the same as how Esau works with Jacob, following your exact movements

    Disappears after the current room or if he takes enough damage and dies

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Forgotten

    * Soul Stone

  • Soul of Bethany

    "Friends from beyond"

    Creates 6 wisps, similar to the Book of Virtues effect

    Mosts wisps will be the standard blue ones, but have a chance to have random special properties

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Bethany

    * Soul Stone

  • Soul of Jacob and Esau

    "Bound by blood"

    Spawns Esau as a temporary familiar, who copies your exact movements the same as how the Jacob & Esau character works

    Disappears after the current room or if he takes enough damage and dies

    UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Jacob

    * Soul Stone